• Room 01.063 - CEM

    United Kingdom

Accepting PhD Students

PhD projects

Professor Grieve is open to wide-ranging PhD applications from candidates with a basic science or clinical background. His fields of interest include: - cardiovascular biology - pathophysiology - pharmacology Previous research experience is desirable although not essential.

19992020
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Personal profile

Research Statement

After being awarded a BSc honours degree by the University of Dundee in 1995, I completed a PhD on ‘The role of dietary lipoproteins in the initiation of atherosclerosis’ at The Royal Veterinary College, University of London, in 1998. I then worked as a post-doctoral researcher in the laboratory of Professor Ajay Shah in the Cardiovascular Division at King’s College London for almost 7 years. In 2005, I took up an academic position within the School of Medicine, Dentistry and Biomedical Sciences at Queen's University Belfast where I am now a Professor with an established independent research programme. Notable achievements include receipt of the International Society for Heart Research Young Investigator Award (2003) and a prestigious Medical Research Council UK New Investigator Research Grant (2007), and election to the committee of the British Society for Cardiovascular Research (2008) on which I served as Honorary Secretary from 2014-2019. I am also currently Vice-Chair of  the British Heart Foundation Projects Grants Committee and Associate Editor of Cardiovascular Drugs and Therapy. To date, I have published 57 peer-reviewed papers in the cardiovascular field in high impact journals such as Circulation, Circulation Research, Journal of the American College of Cardiology and Proceedings of the National Academy of Sciences USA, with >3900 citations and an H-index of 27 (according to Scopus) and have been awarded >£4.1M in competitive research grant funding.

Research Interests

My research programme is mainly focussed on investigating mechanisms underlying cardiovascular remodelling and dysfunction, with a particular interest in the role of oxidative stress, novel peptide hormones, endothelial progenitor cells, and the influence of diabetes. My group employs a wide range of laboratory techniques, from in vivo physiology to molecular biology and tissue culture, to investigate mechanisms underlying the adaptive but ultimately detrimental changes that occur in various cardiovascular disease states and how these may be modulated for potential therapeutic benefit.

Dr Grieve's laboratory page

 

Teaching

I make a significant contribution to both undergraduate and postgraduate teaching across a range of modules:

Undergraduate

MED1017 - Physiological Basis of Clinical Practice
MED2013 - Physiological Basis of Clinical Practice
MED3013 - Student-Selected Component

Biomedical Sciences
BMS2027 - Physiological Sciences
BMS3013 - Sports and Exercise Physiology

Postgraduate

Fingerprint Dive into the research topics where David Grieve is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2006 2019

Research Output 1999 2020

The influence of vestibular stimulation on metabolism and body composition

McKeown, J., McGeoch, P. D. & Grieve, D. J., 01 Jan 2020, In : Diabetic Medicine. 37, 1, p. 20-28 9 p.

Research output: Contribution to journalReview article

Body Composition
Hypothalamus
Obesity
Metabolic Diseases
Fats

British Society for Cardiovascular Research (Special Issue): Introduction

Grieve, D. J., 20 Mar 2019, In : Cardiovascular Drugs and Therapy. 33, 201, p. 1

Research output: Contribution to journalEditorial

Open Access
26 Downloads (Pure)

NOX4 is a major regulator of cord blood-derived endothelial colony-forming cells which promotes postischaemic revascularisation

O'Neill, K. M., Campbell, D. C., Edgar, K. S., Gill, E. K., Moez, A., McLoughlin, K. J., O'Neill, C. L., Dellett, M., Hargey, C. J., Abudalo, R. A., O'Hare, M., Doyle, P., Toh, T., Khoo, J., Wong, J., McCrudden, C. M., Meloni, M., Brunssen, C., Morawietz, H., Yoder, M. C. & 6 others, McDonald, D. M., Watson, C. J., Stitt, A. W., Margariti, A., Medina, R. J. & Grieve, D. J., 01 Apr 2019, In : Cardiovascular Research.

Research output: Contribution to journalArticle

Open Access
File
Fetal Blood
Reactive Oxygen Species
Blood Vessels
Acetates
NADPH Oxidase

P347 A survey of cardiovascular disease in UK cystic fibrosis centres

Downey, D. G., Bengoechea, J., Curtis, T., Grieve, D. & Harbinson, M., Jun 2019, In : Journal of Cystic Fibrosis. 18, p. S155-S156

Research output: Contribution to journalMeeting abstract

1 Citation (Scopus)

The RNA-binding protein QKI controls alternative splicing in vascular cells, producing an effective model for therapy

Caines, R., Cochrane, A., Kelaini, S., Gonzalez, M. V., Yang, C., Eleftheriadou, M., Moez, A., Stitt, A. W., Zeng, L., Grieve, D. J. & Margariti, A., 15 Aug 2019, In : Journal of Cell Science.

Research output: Contribution to journalArticle

RNA-Binding Proteins
Alternative Splicing
Vascular Smooth Muscle
Smooth Muscle Myocytes
Blood Vessels

Prizes

Best Poster Prize - 5th Annual REMERGE Meeting

Karla O'Neill (Recipient) & David Grieve (Recipient), 26 Jun 2017

Prize: Prize (including medals and awards)

Best Poster Prize - Irish Association of Pharmacologists Annual Conference

Rawan Abudalo (Recipient) & David Grieve (Recipient), 30 Nov 2018

Prize: Prize (including medals and awards)

British Heart Foundation Heart Heroes Award

David Grieve (Recipient), 05 Oct 2018

Prize: Prize (including medals and awards)

British Heart Foundation Heart Heroes Award

David Grieve (Recipient), 29 Jun 2017

Prize: Prize (including medals and awards)

British Heart Foundation Project Grants Committee

David Grieve (Recipient), 23 Jan 2017

Prize: Appointment

grant

Activities 2001 2020

Cardiovascular Drugs and Therapy (Journal)

David Grieve (Associate editor)
13 Jan 2020 → …

Activity: Publication peer-review and editorial work typesEditorial activity

Invited Speaker at International Society for Heart Research European Section Meeting

David Grieve (Invited speaker)
30 Jun 202003 Jul 2020

Activity: Talk or presentation typesInvited or keynote talk at national or international conference

Theranostics (Journal)

David Grieve (Peer reviewer)
16 Feb 2019 → …

Activity: Publication peer-review and editorial work typesPublication peer-review

Biochemical Journal (Journal)

David Grieve (Peer reviewer)
15 May 2019 → …

Activity: Publication peer-review and editorial work typesPublication peer-review

Northern Ireland Science Festival - Know Your Enemy

David Grieve (Organiser)
16 Feb 2019

Activity: Other activity typesOther

Press / Media

It’s not just heart research that’s important in Northern Ireland…

David Grieve

17/03/2018

1 Media contribution

Press/Media: Public Engagement Activities

Investing in the future

David Grieve

01/10/2017

1 Media contribution

Press/Media: Other

Warning over number of people ignoring heart attack symptoms

David Grieve

12/04/2016

1 Media contribution

Press/Media: Expert Comment

Half of heart attack patients delay seeking medical help

David Grieve

12/04/2016

1 Media contribution

Press/Media: Expert Comment

How mentoring is helping us develop the research stars of the future

David Grieve

01/10/2015

1 Media contribution

Press/Media: Public Engagement Activities