David Grieve

Kerrigan, L., Edgar, K., Russell-Hallinan, A., Cappa, O., Glezeva, N., Galan-Arriola, C., Oliver, E., Ibanez, B., Baugh, J., Collier, P., Ledwidge, M., McDonald, K., Simpson, D., Das, S., Grieve, D. J. & Watson, C. J., 05 Sept 2024, (Early online date) In: ESC Heart Failure. 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

20 Downloads (Pure)

Methanolic extract of phoenix dactylifera confers protection against experimental diabetic cardiomyopathy through modulation of glucolipid metabolism and cardiac remodeling

Nawaz, L., Grieve, D. J., Muzaffar, H., Iftikhar, A. & Anwar, H., 15 Jul 2024, In: Cells. 13, 14, 20 p., 1196.

Research output: Contribution to journal › Article › peer-review

Open Access

File

8 Downloads (Pure)

NOX4 NADPH oxidase signalling is a key determinant of angiogenic function of cord-blood endothelial colony-forming cells in hypoxia

Pun, S. H., O'Neill, K. M., Naderi-Meshkin, H., Malla, S., Botezatu, B., King, W., Dunne, P. D., Brazil, D. P., Watson, C. J. & Grieve, D. J., 26 Aug 2024, In: Medical Sciences Forum. 27, 1 (2), 1 p., 1.2.

Research output: Contribution to journal › Meeting abstract › peer-review

Progression of diabetic cardiomyopathy exhibits alterations in cardiac function andstructure and macrophages composition

Karuna, N., Kerrigan, L., Edgar, K., Grieve, D. & Watson, C., 28 Aug 2024, In: Medical Sciences Forum. 27, 1 (3), 1 p., 1.2.

Research output: Contribution to journal › Meeting abstract › peer-review

Protection with LCZ696 (sacubitril/valsartan) against diastolic dysfunction and cardiac fibrosis in high-fat diet/streptozotocin mouse model

Karuna, N., Kerrigan, L., Edgar, K., Ledwidge, M., McDonald, K., Grieve, D. & Watson, C., 26 Aug 2024, In: Medical Sciences Forum. 27, 1 (2), 1 p., 1.4.

Research output: Contribution to journal › Meeting abstract › peer-review

SGLT2 inhibition in heart failure: clues to cardiac effects?

Savage, P., Dixon, L., Grieve, D. & Watson, C., 08 Jan 2024, (Early online date) In: Cardiology in Review. 8 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

File

89 Downloads (Pure)

Unveiling impaired vascular function and cellular heterogeneity in diabetic donor-derived vascular organoids

Naderi-Meshkin, H., Setyaningsih, W. A. W., Yacoub, A., Carney, G., Cornelius, V. A., Nelson, C.-A., Kelaini, S., Donaghy, C., Dunne, P. D., Amirkhah, R., Zampetaki, A., Zeng, L., Stitt, A. W., Lois, N., Grieve, D. J. & Margariti, A., Sept 2024, In: Stem Cells. 42, 9, p. 791-808 18 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2 Citations (Scopus)

15 Downloads (Pure)

2023

Blood vessel organoids derived from diabetic patients revealed impaired function based on a subpopulation of endothelial cells

Naderi-Meshkin, H., Eleftheriadou, M., Carney, G., Cornelius, V. A., Nelson, C.-A., Kelaini, S., Yacoub, A., Dunne, P. D., Amirkhah, R., Zampetaki, A., Zeng, L., Stitt, A. W., Lois, N., Grieve, D. J. & Margariti, A., 02 Jun 2023, In: Heart. 109, Suppl 3, 1 p., BS16.

Research output: Contribution to journal › Meeting abstract › peer-review

Open Access

Cardiac organoids: a model to investigate the effect of diabetes on cardiac development and function

Eleftheriadou, M., Naderi-Meshkin, H., Potel, K. N., Setyaningsih, W. A. W., Yacoub, A., Stitt, A. W., Grieve, D. J. & Margariti, A., 02 Jun 2023, In: Heart. 109, Suppl 3

Research output: Contribution to journal › Meeting abstract › peer-review

Oxidative stress and inflammation in COVID-19: potential application OF GLP-1 receptor agonists

Abudalo, R. A., Alqudah, A. M., Roarty, C., Athamneh, R. Y. & Grieve, D. J., 01 Jul 2023, In: European Review for Medical and Pharmacological Sciences. 27, 13, p. 6459-6471 13 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

File

4 Citations (Scopus)

66 Downloads (Pure)

PLAC8-mediated activation of NOX4 signalling restores angiogenic function of endothelial colony-forming cells in experimental hypoxia

Pun, S. H., O’Neill, K. M., Edgar, K. S., Gill, E. K., Moez, A., Naderi-Meshkin, H., Malla, S. B., Hookham, M. B., Alsaggaf, M., Madishetti, V. V., Botezatu, B., King, W., Brunssen, C., Morawietz, H., Dunne, P. D., Brazil, D. P., Medina, R. J., Watson, C. J. & Grieve, D. J., 06 Sept 2023, In: Cells. 12, 18, 19 p., 2220.

Research output: Contribution to journal › Article › peer-review

Open Access

File

1 Citation (Scopus)

68 Downloads (Pure)

Single-nuclei sequencing of diabetic cardiomyopathy mousereveals extent of immune activation and modulated by sacubitril/valsartan

Karuna, N., Kerrigan, L., Ledwidge, M. & Grieve, D., 23 May 2023.

Research output: Contribution to conference › Poster › peer-review

Spatial gene expression changes in the mouse heart after base-targeted irradiation

Walls, G. M., Ghita, M., Queen, R., Edgar, K. S., Gill, E. K., Kuburas, R., Grieve, D. J., Watson, C. J., McWilliam, A., Van Herk, M., Williams, K. J., Cole, A. J., Jain, S. & Butterworth, K. T., 01 Feb 2023, In: International Journal of Radiation Oncology - Biology - Physics. 115, 2, p. 453-463 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

10 Citations (Scopus)

192 Downloads (Pure)

Targeted mobilisation of endogenous endothelial progenitor cells - an alternate approach to allogeneic therapy for ischaemic cardiovasular disease?

O'Neill, K. M. & Grieve, D. J., 03 May 2023, (Early online date) In: Cardiovascular Drugs and Therapy.

Research output: Contribution to journal › Editorial › peer-review

Who should be the corresponding author, what are their responsibilities, and what email address should they provide?

Birnbaum, Y., Kitakaze, M., Grieve, D. & Uretsky, B. F., Dec 2023, In: Cardiovascular Drugs and Therapy. 37, 6, p. 1039–1040 2 p.

Research output: Contribution to journal › Editorial › peer-review

2022

Loss of TRPV2-mediated blood flow autoregulation recapitulates diabetic retinopathy in rats

O'Hare, M., Esquiva, G., McGahon, M. K., Hombrebueno, J. M. R., Augustine, J., Canning, P., Edgar, K. S., Barabas, P., Friedel, T., Cincolà, P., Henry, J., Mayne, K., Ferrin, H., Stitt, A. W., Lyons, T. J., Brazil, D. P., Grieve, D. J., McGeown, J. G. & Curtis, T. M., 22 Sept 2022, In: JCI insight. 7, 18, 18 p., e155128.

Research output: Contribution to journal › Article › peer-review

Open Access

File

12 Citations (Scopus)

60 Downloads (Pure)

The study of diabetic cardiomyopathy progression in a mouse model using high-fat diet and high-dose of streptozotocin

Karuna, N., Kerrigan, L., Edgar, K., Grieve, D. J. & Watson, C. J., 05 Feb 2022.

Research output: Contribution to conference › Paper › peer-review

2021

ECSIT is a critical limiting factor for cardiac function

Xu, L., Humphries, F., Delagic, N., Wang, B., Holland, A., Edgar, K. S., Hombrebueno, J. R., Stolz, D. B., Oleszycka, E., Rodgers, A. M., Glezeva, N., McDonald, K., Watson, C. J., Ledwidge, M. T., Ingram, R. J., Grieve, D. J. & Moynagh, P. N., 22 Jun 2021, (Early online date) In: JCI insight. 6, 12, e142801.

Research output: Contribution to journal › Article › peer-review

Open Access

File

12 Citations (Scopus)

67 Downloads (Pure)

Epigenetic regulation of endothelial cell function by nucleic acid methylation in cardiac homeostasis and disease

Russell-Hallinan, A., Watson, C. J., O'Dwyer, D., Grieve, D. J. & O'Neill, K. M., 01 Oct 2021, In: Cardiovascular Drugs and Therapy. 35, p. 1025-1044 20 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

File

11 Citations (Scopus)

178 Downloads (Pure)

FKBPL and SIRT-1 Are Downregulated by Diabetes in Pregnancy Impacting on Angiogenesis and Endothelial Function

Alqudah, A., Eastwood, K.-A., Jerotic, D., Todd, N., Hoch, D., McNally, R., Obradovic, D., Dugalic, S., Hunter, A. J., Holmes, V. A., McCance, D. R., Young, I. S., Watson, C. J., Robson, T., Desoye, G., Grieve, D. J. & McClements, L., 02 Jun 2021, In: Frontiers in Endocrinology. 12, 650328.

Research output: Contribution to journal › Article › peer-review

Open Access

File

24 Citations (Scopus)

75 Downloads (Pure)

GSTM1 Modulates Expression of Endothelial Adhesion Molecules in Uremic Milieu

Jerotic, D., Suvakov, S., Matic, M., Alqudah, A., Grieve, D. J., Pljesa-Ercegovac, M., Savic-Radojevic, A., Damjanovic, T., Dimkovic, N., McClements, L. & Simic, T., 27 Jan 2021, In: Oxidative Medicine and Cellular Longevity. 2021, 6678924.

Research output: Contribution to journal › Article › peer-review

Open Access

File

8 Citations (Scopus)

59 Downloads (Pure)

Induced Pluripotent Stem Cell-Derived Endothelial Cells From Human Diabetic Donors Carry an Imprint of the Diabetic Milieu

Eleftheriadou, M., Naderi-Meshkin, H., Yacoub, A., Morrison, T., Cornelius, V., Yang, C., Vila-Gonzalez, M., Kelaini, S., Carney, G., Lopez Campos, G., Lois, N., Grieve, D., Stitt, A. & Margariti, A., 04 Jun 2021, In: Heart (British Cardiovascular Society). 107, Suppl 1, p. 107

Research output: Contribution to journal › Meeting abstract › peer-review

Open Access

Role of a novel angiogenesis FKBPL-CD44 pathway in preeclampsia risk stratification and mesenchymal stem cell treatment

Todd, N., McNally, R., Alqudah, A., Jerotic, D., Suvakov, S., Obradovic, D., Hoch, D., Hombrebueno, J. R., Campos, G. L., Watson, C. J., Gojnic-Dugalic, M., Simic, T. P., Krasnodembskaya, A., Desoye, G., Eastwood, K.-A., Hunter, A. J., Holmes, V. A., McCance, D. R., Young, I. S. & Grieve, D. J. & 4 others, Kenny, L. C., Garovic, V. D., Robson, T. & McClements, L., 02 Jan 2021, In: The Journal of Clinical Endocrinology & Metabolism. 106, 1, p. 26-41 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

30 Citations (Scopus)

77 Downloads (Pure)

2020

Author Correction: Targeting QKI-7 in vivo restores endothelial cell function in diabetes (Nature Communications, (2020), 11, 1, (3812), 10.1038/s41467-020-17468-y)

Yang, C., Eleftheriadou, M., Kelaini, S., Morrison, T., González, M. V., Caines, R., Edwards, N., Yacoub, A., Edgar, K., Moez, A., Ivetic, A., Zampetaki, A., Zeng, L., Wilkinson, F. L., Lois, N., Stitt, A. W., Grieve, D. J. & Margariti, A., 01 Dec 2020, In: Nature Communications. 11, 1, 1 p., 4770.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

1 Citation (Scopus)

Cardiac sub-volume targeting demonstrates regional radiosensitivity in the mouse heart

Ghita, M., Gill, E., Walls, G., Edgar, K., McMahon, S., Vasquez Osorio, E., Bergom, C., Grieve, D., Watson, C., McWilliam, A., Aznar, M., van herk, M., Williams, K. J. & Butterworth, K., 11 Jul 2020, In: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology. DOI: 10.1016/j.radonc.2020.07.016 .

Research output: Contribution to journal › Article › peer-review

Open Access

File

28 Citations (Scopus)

218 Downloads (Pure)

Clearance of senescent cells during cardiac ischemia–reperfusion injury improves recovery

Dookun, E., Walaszczyk, A., Redgrave, R., Palmowski, P., Tual-Chalot, S., Suwana, A., Chapman, J., Jirkovsky, E., Donastorg Sosa, L., Gill, E., Yausep, O. E., Santin, Y., Mialet-Perez, J., Andrew Owens, W., Grieve, D., Spyridopoulos, I., Taggart, M., Arthur, H. M., Passos, J. F. & Richardson, G. D., 01 Oct 2020, In: Aging cell. 19, 10, e13249.

Research output: Contribution to journal › Article › peer-review

Open Access

File

99 Citations (Scopus)

65 Downloads (Pure)

Downregulation of PPARα during Experimental Left Ventricular Hypertrophy Is Critically Dependent on Nox2 NADPH Oxidase Signalling

Harvey, A. P., Robinson, E., Edgar, K. S., McMullan, R., O'Neill, K. M., Alderdice, M., Amirkhah, R., Dunne, P. D., McDermott, B. J. & Grieve, D. J., 20 Jun 2020, In: International journal of molecular sciences. 21, 12

Research output: Contribution to journal › Article › peer-review

Open Access

File

12 Citations (Scopus)

78 Downloads (Pure)

Endothelial cells derived from patients with diabetic macular edema recapitulate clinical evaluations of anti-VEGF responsiveness through the Neuronal Pentraxin 2 pathway

Vila-Gonzalez, M., Kelaini, S., Naderi-Meshkin, H., Margariti, A., Stewart, S., Virgili, G., Grieve, D. J., Stitt, A. W., Lois, N. & Margariti, A., 13 Aug 2020, (Early online date) In: Diabetes.

Research output: Contribution to journal › Article › peer-review

Open Access

File

10 Citations (Scopus)

426 Downloads (Pure)

FKBPL and SIRT-1, key angiogenesis proteins, are downregulated by diabetes in pregnancy

Alqudah, A., Eastwood, K. A., Jerotic, D., Todd, N., Hoch, D., McNally, R., Obradovic, D., Dugalic, S., Hunter, A. J., Holmes, V. A., McCance, D. R., Young, I. S., Watson, C. J., Robson, T., Desoye, G., Grieve, D. J. & McClements, L., 08 Oct 2020, medRxiv, (medRxiv).

Research output: Working paper

NOX4 is a major regulator of cord blood-derived endothelial colony-forming cells which promotes postischaemic revascularisation

O'Neill, K. M., Campbell, D. C., Edgar, K. S., Gill, E. K., Moez, A., McLoughlin, K. J., O'Neill, C. L., Dellett, M., Hargey, C. J., Abudalo, R. A., O'Hare, M., Doyle, P., Toh, T., Khoo, J., Wong, J., McCrudden, C. M., Meloni, M., Brunssen, C., Morawietz, H. & Yoder, M. C. & 6 others, McDonald, D. M., Watson, C. J., Stitt, A. W., Margariti, A., Medina, R. J. & Grieve, D. J., 01 Feb 2020, In: Cardiovascular Research. 116, 2, p. 393-405

Research output: Contribution to journal › Article › peer-review

Open Access

File

16 Citations (Scopus)

18254 Downloads (Pure)

Targeting QKI-7 in vivo restores endothelial cell function in diabetes

Yang, C., Eleftheriadou, M., Kelaini, S., Morrison, T., González, M. V., Caines, R., Edwards, N., Yacoub, A., Edgar, K., Moez, A., Ivetic, A., Zampetaki, A., Zeng, L., Wilkinson, F. L., Lois, N., Stitt, A. W., Grieve, D. J. & Margariti, A., 30 Jul 2020, In: Nature Communications. 11, 1, 17 p., 3812.

Research output: Contribution to journal › Article › peer-review

Open Access

File

48 Citations (Scopus)

167 Downloads (Pure)

The British Society for Cardiovascular Research Autumn 2019 Meeting Incorporating the Bernard and Joan Marshall Research Awards

Sinha, S. & Grieve, D. J., 15 Feb 2020, In: Cardiovascular Drugs and Therapy. 34, 2, p. 227-230 4 p.

Research output: Contribution to journal › Editorial › peer-review

1 Citation (Scopus)

The influence of vestibular stimulation on metabolism and body composition

McKeown, J., McGeoch, P. D. & Grieve, D. J., 01 Jan 2020, In: Diabetic Medicine. 37, 1, p. 20-28 9 p.

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

2019

British Society for Cardiovascular Research (Special Issue): Introduction

Grieve, D. J., 20 Mar 2019, In: Cardiovascular Drugs and Therapy. 33, 201, p. 1

Research output: Contribution to journal › Editorial › peer-review

Open Access

Endothelial cell Nox4 is an important regulator of cardiac ROS signalling and adverse remodelling in experimental diabetes

Gill, E., Edgar, K., Hargey, C., Moez, A., Wilson, A. J., Patterson, E., Wong, X. N. J., Curtis, T. & Grieve, D., 03 Jun 2019.

Research output: Contribution to conference › Abstract › peer-review

Induced pluripotent stem cell-derived endothelial cells from human diabetic donors carry an imprint of the diabetic milieu

Eleftheriadou, M., Morrison, T., Vila-Gonzalez, M., Kelaini, S., Flanagan, S., Lopez Campos, G., Grieve, D., Stitt, A. & Margariti, A., 2019.

Research output: Contribution to conference › Abstract › peer-review

P347 A survey of cardiovascular disease in UK cystic fibrosis centres

Downey, D. G., Bengoechea, J., Curtis, T., Grieve, D. & Harbinson, M., Jun 2019, In: Journal of Cystic Fibrosis. 18, p. S155-S156

Research output: Contribution to journal › Meeting abstract › peer-review

The RNA-binding protein QKI controls alternative splicing in vascular cells, producing an effective model for therapy

Caines, R., Cochrane, A., Kelaini, S., Gonzalez, M. V., Yang, C., Eleftheriadou, M., Moez, A., Stitt, A. W., Zeng, L., Grieve, D. J. & Margariti, A., 15 Aug 2019, (Early online date) In: Journal of Cell Science.

Research output: Contribution to journal › Article › peer-review

Open Access

File

26 Citations (Scopus)

129 Downloads (Pure)

2018

Adverse cardiac remodelling in experimental diabetes is regulated by endothelial Nox4 NADPH oxidase-derived reactive oxygen species

Edgar, K., Gill, E., Patterson, E., Hargey, C., Moez, A. & Grieve, D., 16 Jul 2018.

Research output: Contribution to conference › Abstract › peer-review

Biochemical properties and biological actions of obestatin and its relevence in type 2 diabetes

Green, B. D. & Grieve, D. J., 03 Feb 2018, In: Peptides. 100, p. 249-259 11 p.

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Vilà-González, M., Kelaini, S., Magee, C., Caines, R., Campbell, D., Eleftheriadou, M., Cochrane, A., Drehmer, D., Tsifaki, M., O'Neill, K., Pedrini, E., Yang, C., Medina, R., McDonald, D., Simpson, D., Zampetaki, A., Zeng, L., Grieve, D., Lois, N. & Stitt, A. W. & 1 others, Margariti, A., 17 Nov 2018, In: Stem Cells. 37, 2, p. 226

Research output: Contribution to journal › Article › peer-review

Open Access

File

21 Citations (Scopus)

481 Downloads (Pure)

Follistatin-Like 3 Enhances the Function of Endothelial Cells Derived from Pluripotent Stem Cells by Facilitating β-Catenin Nuclear Translocation Through Inhibition of Glycogen Synthase Kinase-3β Activity

Kelaini, S., Vilà-González, M., Caines, R., Campbell, D., Eleftheriadou, M., Tsifaki, M., Magee, C., Cochrane, A., O'Neill, K., Yang, C., Stitt, A. W., Zeng, L., Grieve, D. J. & Margariti, A., 01 Jul 2018, In: Stem Cells. 36, 7, p. 1033-1044

Research output: Contribution to journal › Article › peer-review

Open Access

File

19 Citations (Scopus)

247 Downloads (Pure)

Glucagon-like peptide-1 analogues exert differential in vitro actions on macrophages and cardiac fibroblasts in experimental diabetes

Abudalo, R., Edgar, K., O'Neill, K., Grieve, D. & Green, B., 06 Jun 2018.

Research output: Contribution to conference › Abstract › peer-review

David Grieve

Research output

Search results