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David Hirst

Professor

20002016
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Fingerprint Dive into the research topics where David Hirst is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 9 Similar Profiles
Bradykinin Chemical Compounds
Anura Medicine & Life Sciences
Nanoparticles Medicine & Life Sciences
Gold Medicine & Life Sciences
Skin Chemical Compounds
Peptides Chemical Compounds
Neoplasms Medicine & Life Sciences
Genetic Therapy Medicine & Life Sciences

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Research Output 2000 2016

56 Citations (Scopus)
211 Downloads (Pure)

Imaging and radiation effects of gold nanoparticles in tumour cells

McQuaid, H. N., Muir, M. F., Taggart, L. E., McMahon, S. J., Coulter, J. A., Hyland, W. B., Jain, S., Butterworth, K. T., Schettino, G., Prise, K. M., Hirst, D., Botchway, S. W. & Currell, F., 20 Jan 2016, In : Scientific Reports. 6, 10 p., 19442.

Research output: Contribution to journalArticle

Open Access
File
Radiation Effects
Gold
Nanoparticles
DNA Damage
Neoplasms
9 Citations (Scopus)
153 Downloads (Pure)

Vasoactivity of Rucaparib, a PARP-1 Inhibitor, is a Complex Process that Involves Myosin Light Chain Kinase, P2 Receptors, and PARP Itself

McCrudden, C. M., O'Rourke, M. G., Cherry, K. E., Yuen, H-F., O'Rourke, D., Babur, M., Telfer, B. A., Thomas, H. D., Keane, P., Nambirajan, T., Hagan, C., O'Sullivan, J. M., Shaw, C., Williams, K. J., Curtin, N. J., Hirst, D. G. & Robson, T., 17 Feb 2015, In : PloS one. 10, 2, 16 p., e0118187.

Research output: Contribution to journalArticle

Open Access
File
myosin light chain kinase
Myosin-Light-Chain Kinase
NAD ADP-ribosyltransferase
Poly(ADP-ribose) Polymerases
vasodilation
46 Citations (Scopus)

Gold nanoparticle cellular uptake, toxicity and radiosensitisation in hypoxic conditions

Jain, S., Coulter, J. A., Butterworth, K. T., Hounsell, A. R., McMahon, S. J., Hyland, W. B., Muir, M. F., Dickson, G. R., Prise, K. M., Currell, F. J., Hirst, D. G. & O'Sullivan, J. M., Feb 2014, In : Radiotherapy and Oncology. 110, 2, p. 342-347 6 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
212 Downloads (Pure)

The Anti-Migratory Effects of FKBPL and Its Peptide Derivative, AD-01: Regulation of CD44 and the Cytoskeletal Pathway

Yakkundi, A., McCallum, L., O'Kane, A., Dyer, H., Worthington, J., McKeen, H. D., McClements, L., Elliott, C., McCarthy, H. O., Hirst, D. G. & Robson, T., 15 Feb 2013, In : PLoS ONE. 8, 2, 11 p., e55075.

Research output: Contribution to journalArticle

Open Access
File
Tacrolimus Binding Proteins
binding proteins
chemical derivatives
peptides
Derivatives
11 Citations (Scopus)
151 Downloads (Pure)

The contribution of N₂O₃ to the cytotoxicity of the nitric oxide donor DETA/NO: an emerging role for S-nitrosylation

Ali, A. A., Coulter, J. A., Ogle, C. H., Migaud, M. M., Hirst, D. G., Robson, T. & McCarthy, H. O., 01 Apr 2013, In : Bioscience Reports. 33, 2, p. 333-349 23 p.

Research output: Contribution to journalArticle

Open Access
File
Nitric Oxide Donors
Cytotoxicity
Reactive Nitrogen Species
1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene
Oxygen