David Jones

2020

Effect of carrier type and surfactant concentration on the silymarin release

Mohylyuk, V., Pauly, T., Dobrovolnyi, O., Scott, N., Jones, D. & Andrews, G., 06 Feb 2020, (Accepted). 2 p.

Research output: Contribution to conference › Abstract

Formulation of sustained release lipid-based matrix system for vaginal delivery using the twin-screw hot-melt extrusion method

Mohylyuk, V., Hutton, T., Dadou, S., Tian, J., Li, S., Jones, D. & Andrews, G., 06 Feb 2020, (Accepted). 2 p.

Research output: Contribution to conference › Abstract

The development and validation of a quality by design based process analytical tool for the inline quantification of Ramipril during hot-melt extrusion

Dadou, S., Senta Loys, Z., Almajaan, A., Li, S., Jones, D., Healy, A. M., Tian, J. & Andrews, G., 25 Apr 2020, (Accepted) In : International Journal of Pharmaceutics. 584

Research output: Contribution to journal › Article

2019

A statistical determination of the contribution of viscoelasticity of aqueous carbohydrate polymer networks to drug release

Jones, D. S., Yu, T. & Andrews, G. P., 15 Feb 2019, In : Carbohydrate Polymers. 206, p. 511-519 9 p.

Research output: Contribution to journal › Article

A validated size exclusion chromatography method coupled with fluorescence detection for rapid quantification of bevacizumab in ophthalmic formulations

Jirjees, F., Soliman, K., Wang, Y., Sonawane, R., Sheshala, R., Jones, D. & Singh, T. R. R., 22 May 2019, In : Journal of Pharmaceutical and Biomedical Analysis.

Research output: Contribution to journal › Article

Open Access

File

4 Downloads (Pure)

Co-extruded Fixed Dose Combination Products with Enabled Properties for the Treatment of Cardiovascular Diseases

Almajaan, A., Li, S., Gilvary, G. C., Senta Loys, Z., Tian, Y., Kelleher, J., Healy, A-M., Jones, D. & Andrews, G., 03 Apr 2019.

Research output: Contribution to conference › Paper

Open Access

Comparative In Vitro Assessment of a Range of Commercial Feed Additives with Multiple Mycotoxin Binding Claims

Kolawole, O., Meneely, J., Greer, B., Chevallier, O., Jones, D. S., Connolly, L. & Elliott, C., 12 Nov 2019, In : Toxins. 11, 11, 14 p., 659.

Research output: Contribution to journal › Article

Open Access

File

1 Citation (Scopus)

56 Downloads (Pure)

Fixed Dose Combination Formulations: Multi-Layered Platforms Designed for the Management of Cardiovascular Disease

Andrews, G. P., Li, S., Almajaan, A., Yu, T., Martini, L., Healy, A. M. & Jones, D. S., 06 May 2019, In : Molecular Pharmaceutics. 16, 5, p. 1827-1838 12 p.

Research output: Contribution to journal › Article

Open Access

File

1 Citation (Scopus)

47 Downloads (Pure)

In situ forming photocrosslinked biodegradable implants for sustained delivery of proteins

Thakur, R., Wang, Y., Soliman, K., Sonawane, R. & Jones, D., Apr 2019.

Research output: Contribution to conference › Poster

Mechanochemical synthesis of a multicomponent complex containing albendazole and maleic acid for improved physiochemical properties

Culkin, A., Jones, D., Andrews, G. & Li, S., Nov 2019.

Research output: Contribution to conference › Poster

Metformin Hydrochloride and Sitagliptin Phosphate Fixed Dose Combination Product Prepared Using Melt Granulation Continuous Processing Technology

Kelleher, J., Madi, A., Gilvary, G. C., Tian, J., Li, S., Almajaan, A., Senta Loys, Z., Jones, D., Andrews, G. & Healy, A. M., 12 Dec 2019, In : AAPS PharmSciTech. 21, 1, 14 p.

Research output: Contribution to journal › Article

Novel biodegradable photocrosslinked implants for sustained ocular delivery of triamcinolone acetonide

Thakur, R., Wang, Y., Sonawane, R., Soliman, K. & Jones, D., Apr 2019.

Research output: Contribution to conference › Poster

Poloxamer-based in situ gelling thermoresponsive systems for ocular drug delivery applications

Soliman, K., Jones, D. & Thakur, R., 06 Jun 2019, In : Drug Discovery Today.

Research output: Contribution to journal › Article

8 Citations (Scopus)

Raman Spectroscopic Analysis as a Process Analytical Technique when Manufacturing Hot Melt Extruded Anti-Hypertension Compatible Monolithic Fixed-Dose Combination Products

Gilvary, G. C., Dadou, S., Tian, J., Li, S., Jones, D. & Andrews, G., Sep 2019.

Research output: Contribution to conference › Poster

Solvent and water free lipid-based nanoparticles and their methods of manufacture

Andrews, G., Jones, D. & Tian, Y., Jan 2019, Patent No. United Kingdom 1900389.6

Research output: Patent

The development of an inline Raman spectroscopic analysis method as a quality control tool for hot melt extruded ramipril fixed-dose combination products

Andrews, G. P., Jones, D. S., Senta-Loys, Z., Almajaan, A., Li, S., Chevallier, O., Elliott, C., Healy, A-M., Kelleher, J., Madi, A., Gilvary, G. C. & Tian, Y., 20 Jul 2019, In : International Journal of Pharmaceutics. 566, p. 476-487 12 p.

Research output: Contribution to journal › Article

Open Access

File

2 Citations (Scopus)

6 Downloads (Pure)

The investigation of Flory-Huggins interaction parameters for amorphous solid dispersion across the entire temperature and composition range

Tian, Y., Qian, K., Jacobs, E., Amstad, E., Jones, D. S., Stella, L. & Andrews, G. P., 19 Aug 2019, In : Pharmaceutics. 11, 25 p., 420.

Research output: Contribution to journal › Article

Open Access

File

76 Downloads (Pure)

Understanding the physicochemical properties and degradation kinetics of nicotinamide riboside, a promising vitamin B3nutritional supplement

Campbell, M. T. D., Jones, D. S., Andrews, G. P. & Li, S., 21 Nov 2019, In : Food & Nutrition Research. 63, 11 p., 3419.

Research output: Contribution to journal › Article

Open Access

File

48 Downloads (Pure)

2018

A Comparative Study between Hot-Melt Extrusion and Spray-Drying for the Manufacture of Anti-Hypertension Compatible Monolithic Fixed-Dose Combination Products

Kelleher, J. F., Gilvary, G. C., Madi, A. M., Jones, D. S., Li, S., Tian, Y., Almajaan, A., Senta Loys, Z., Andrews, G. P. & Healy, A. M., 03 May 2018, In : International Journal of Pharmaceutics.

Research output: Contribution to journal › Article

Open Access

File

13 Citations (Scopus)

196 Downloads (Pure)

Anti-adherent biomaterials for prevention of catheter biofouling

McCoy, C. P., Irwin, N. J., Donnelly, L., Jones, D. S., Hardy, J. G. & Carson, L., 15 Jan 2018, In : International Journal of Pharmaceutics. 535, 1-2, p. 420-427 8 p.

Research output: Contribution to journal › Article

Open Access

File

6 Citations (Scopus)

204 Downloads (Pure)

Comparing human peritoneal fluid and phosphate-buffered saline for drug delivery: Do we need bio-relevant media?

Bhusal, P., Rahiri, J. L., Sua, B., McDonald, J. E., Bansal, M., Hanning, S., Sharma, M., Chandramouli, K., Harrison, J., Procter, G., Andrews, G., Jones, D. S., Hill, A. G. & Svirskis, D., 26 Mar 2018, In : Drug Delivery and Translational Research. 8, 3, p. 708-718 11 p.

Research output: Contribution to journal › Article

3 Citations (Scopus)

Construction of Drug-Lipid Thermodynamic Phase diagrams by Analysis of Melting Point Depression through Application of Flory-Huggins Interaction Theory

Cullen, S., Jones, D., Andrews, G. & Tian, Y., Nov 2018.

Research output: Contribution to conference › Poster

Hot-Melt Co-extrusion Technology as a Manufacturing Platform for Anti-hypertensive Fixed-Dose Combinations

Gilvary, G. C., Almajaan, A., Li, S., Senta Loys, Z., Tian, Y., Kelleher, J., Madi, A., Healy, A. M., Jones, D. & Andrews, G., 07 Nov 2018.

Research output: Contribution to conference › Poster

Inline Raman monitoring and analysis of carbamazepine polymorphic form transformation using twin screw extrusion (TSE) platform

Lynch, P., Jones, D., Li, S., Andrews, G. & Tian, Y., Nov 2018.

Research output: Contribution to conference › Poster

In-Line Raman Spectroscopy to highlight Ramipril content and its degraded product during HME process.

Senta Loys, Z., Tian, Y., Almajaan, A., Jones, D. & Andrews, G., Mar 2018.

Research output: Contribution to conference › Poster

In-Situ Forming Phase-inversion Injectable Hydrogels for Controlled Drug Release

Thakur, R., McMillan, H., Sheshala, R., Tekko, I., Alshammari, F. & Jones, D., 28 Feb 2018, Hydrogels: Design, Synthesis & Application in Drug Delivery & Regenerative Medicine. Singh, R. R., Laverty, G. & Donnelly, R. (eds.). CRC Press, p. 228 249 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Long-Acting Biodegradable Implants for Ocular Delivery Of Small And Large Molecules

Sonawane, R., Thakur, R., Soliman, K., Wang, Y. & Jones, D., May 2018.

Research output: Contribution to conference › Poster

Manufacture of a Fixed Dose Combination Product for the Treatment of Type II Diabetes by Hot Melt Continuous Granulation

Madi, A., Kelleher, J., Gilvary, G. C., Jones, D., Li, S., Tian, Y., Almajaan, A., Senta Loys, Z., Andrews, G. & Healy, A-M., 07 Nov 2018.

Research output: Contribution to conference › Poster

Metal Nanoparticle-Hydrogel nanocomposites for Biomedical Applications – an Atmospheric Pressure Plasma Synthesis Approach

Nolan, H., Sun, D., Falzon, B., Chakrabarti, S., Babu, D., Maguire, P., Mariotti, D., Yu, T., Jones, D., Andrews, G. & Sun, D., 09 Oct 2018, In : Plasma Processes and Polymers. 15, 11, 10 p., 1800112.

Research output: Contribution to journal › Article

Open Access

File

8 Citations (Scopus)

163 Downloads (Pure)

Ocular Drug Delivery Using Novel Photocrosslinked Implants

Adrianto, M., Soliman, K., Sonawane, R., Thakur, R., Jones, D. & Wang, Y., May 2018.

Research output: Contribution to conference › Poster

Synthesis and characterisation of photocrosslinked poly(ethylene glycol) diacrylate  implants for sustained ocular drug delivery

McAvoy, K., Jones, D. & Thakur, R. R. S., Feb 2018, In : Pharmaceutical Research. 35, 2, 17 p., 36.

Research output: Contribution to journal › Article

Open Access

File

18 Citations (Scopus)

270 Downloads (Pure)

2017

A new method of constructing drug-polymer temperature-composition phase diagram relevant to the hot-melt extrusion platform

Tian, Y., Jones, D., Donnelly, C., Brannigan, T., Li, S. & Andrews, G., 05 Dec 2017, In : Molecular Pharmaceutics. p. 1-39

Research output: Contribution to journal › Article

Open Access

File

5 Citations (Scopus)

243 Downloads (Pure)

Exploitation of biomarkers for triggered drug delivery of therapeutics from infection-responsive coating technology

Irwin, N., McCoy, C., Gorman, S. & Jones, D., 07 Apr 2017.

Research output: Contribution to conference › Paper

GI Site-Specific Drug Release of HME Matrices to Overcome Limitations of Pre-systemic Metabolism Part I: pH Dependent Systems

Li, S., Almajaan, A., Tian, Y., Senta Loys, Z., Gilvary, G., Kelleher, J., Madi, A., Healy, A. M., Jones, D. & Andrews, G., 13 Nov 2017.

Research output: Contribution to conference › Poster

Hot-Melt Co-Extrusion Technology as a Platform for Manufacturing of Fixed-Dose Combinations with Differing Release Behaviour for the Treatment of Hypertension

Gilvary, G. C., Almajaan, A., DePauw, L., Li, S., Tian, Y., Senta Loys, Z., Kelleher, J., Madi, A., Healy, A. M., Jones, D. & Andrews, G., 13 Nov 2017.

Research output: Contribution to conference › Poster