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David Jones

Professor

  • Room 01.032 - Lanyon Building

    United Kingdom

Accepting PhD Students

PhD projects

Biocompatible implants for improved pain control post-surgery Mucoadhesive platforms for enhanced drug delivery to the oral cavity Production methods for mucoadhesive microspheres based on fluid dynamics

1990 …2020

Research output per year

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Research Output

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Article
2020

The design and development of high drug loading amorphous solid dispersion for hot-melt extrusion platform

Tian, Y., Jacobs, E., Jones, D. S., McCoy, C. P., Wu, H. & Andrews, G. P., 14 Jun 2020, In : International Journal of Pharmaceutics. 586, 119545.

Research output: Contribution to journal › Article

The development and validation of a quality by design based process analytical tool for the inline quantification of Ramipril during hot-melt extrusion

Dadou, S., Senta Loys, Z., Almajaan, A., Li, S., Jones, D., Healy, A. M., Tian, J. & Andrews, G., 30 Jun 2020, In : International Journal of Pharmaceutics. 584

Research output: Contribution to journal › Article

2 Citations (Scopus)
2019

A statistical determination of the contribution of viscoelasticity of aqueous carbohydrate polymer networks to drug release

Jones, D. S., Yu, T. & Andrews, G. P., 15 Feb 2019, In : Carbohydrate Polymers. 206, p. 511-519 9 p.

Research output: Contribution to journal › Article

A validated size exclusion chromatography method coupled with fluorescence detection for rapid quantification of bevacizumab in ophthalmic formulations

Jirjees, F., Soliman, K., Wang, Y., Sonawane, R., Sheshala, R., Jones, D. & Singh, T. R. R., 22 May 2019, In : Journal of Pharmaceutical and Biomedical Analysis.

Research output: Contribution to journal › Article

Open Access
File
17 Downloads (Pure)

Comparative In Vitro Assessment of a Range of Commercial Feed Additives with Multiple Mycotoxin Binding Claims

Kolawole, O., Meneely, J., Greer, B., Chevallier, O., Jones, D. S., Connolly, L. & Elliott, C., 12 Nov 2019, In : Toxins. 11, 11, 14 p., 659.

Research output: Contribution to journal › Article

Open Access
File
3 Citations (Scopus)
65 Downloads (Pure)

Fixed Dose Combination Formulations: Multi-Layered Platforms Designed for the Management of Cardiovascular Disease

Andrews, G. P., Li, S., Almajaan, A., Yu, T., Martini, L., Healy, A. M. & Jones, D. S., 06 May 2019, In : Molecular Pharmaceutics. 16, 5, p. 1827-1838 12 p.

Research output: Contribution to journal › Article

Open Access
File
2 Citations (Scopus)
59 Downloads (Pure)

Metformin Hydrochloride and Sitagliptin Phosphate Fixed Dose Combination Product Prepared Using Melt Granulation Continuous Processing Technology

Kelleher, J., Madi, A., Gilvary, G. C., Tian, J., Li, S., Almajaan, A., Senta Loys, Z., Jones, D., Andrews, G. & Healy, A. M., 12 Dec 2019, In : AAPS PharmSciTech. 21, 1, 14 p.

Research output: Contribution to journal › Article

Poloxamer-based in situ gelling thermoresponsive systems for ocular drug delivery applications

Soliman, K., Jones, D. & Thakur, R., 06 Jun 2019, In : Drug Discovery Today.

Research output: Contribution to journal › Article

Open Access
File
10 Citations (Scopus)
24 Downloads (Pure)

The development of an inline Raman spectroscopic analysis method as a quality control tool for hot melt extruded ramipril fixed-dose combination products

Andrews, G. P., Jones, D. S., Senta-Loys, Z., Almajaan, A., Li, S., Chevallier, O., Elliott, C., Healy, A-M., Kelleher, J., Madi, A., Gilvary, G. C. & Tian, Y., 20 Jul 2019, In : International Journal of Pharmaceutics. 566, p. 476-487 12 p.

Research output: Contribution to journal › Article

Open Access
File
2 Citations (Scopus)
21 Downloads (Pure)

The investigation of Flory-Huggins interaction parameters for amorphous solid dispersion across the entire temperature and composition range

Tian, Y., Qian, K., Jacobs, E., Amstad, E., Jones, D. S., Stella, L. & Andrews, G. P., 19 Aug 2019, In : Pharmaceutics. 11, 25 p., 420.

Research output: Contribution to journal › Article

Open Access
File
1 Citation (Scopus)
84 Downloads (Pure)

Understanding the physicochemical properties and degradation kinetics of nicotinamide riboside, a promising vitamin B3nutritional supplement

Campbell, M. T. D., Jones, D. S., Andrews, G. P. & Li, S., 21 Nov 2019, In : Food & Nutrition Research. 63, 11 p., 3419.

Research output: Contribution to journal › Article

Open Access
File
61 Downloads (Pure)
2018

A Comparative Study between Hot-Melt Extrusion and Spray-Drying for the Manufacture of Anti-Hypertension Compatible Monolithic Fixed-Dose Combination Products

Kelleher, J. F., Gilvary, G. C., Madi, A. M., Jones, D. S., Li, S., Tian, Y., Almajaan, A., Senta Loys, Z., Andrews, G. P. & Healy, A. M., 03 May 2018, In : International Journal of Pharmaceutics.

Research output: Contribution to journal › Article

Open Access
File
15 Citations (Scopus)
227 Downloads (Pure)

Anti-adherent biomaterials for prevention of catheter biofouling

McCoy, C. P., Irwin, N. J., Donnelly, L., Jones, D. S., Hardy, J. G. & Carson, L., 15 Jan 2018, In : International Journal of Pharmaceutics. 535, 1-2, p. 420-427 8 p.

Research output: Contribution to journal › Article

Open Access
File
6 Citations (Scopus)
221 Downloads (Pure)

Comparing human peritoneal fluid and phosphate-buffered saline for drug delivery: Do we need bio-relevant media?

Bhusal, P., Rahiri, J. L., Sua, B., McDonald, J. E., Bansal, M., Hanning, S., Sharma, M., Chandramouli, K., Harrison, J., Procter, G., Andrews, G., Jones, D. S., Hill, A. G. & Svirskis, D., 26 Mar 2018, In : Drug Delivery and Translational Research. 8, 3, p. 708-718 11 p.

Research output: Contribution to journal › Article

3 Citations (Scopus)

Metal Nanoparticle-Hydrogel nanocomposites for Biomedical Applications – an Atmospheric Pressure Plasma Synthesis Approach

Nolan, H., Sun, D., Falzon, B., Chakrabarti, S., Babu, D., Maguire, P., Mariotti, D., Yu, T., Jones, D., Andrews, G. & Sun, D., 09 Oct 2018, In : Plasma Processes and Polymers. 15, 11, 10 p., 1800112.

Research output: Contribution to journal › Article

Open Access
File
8 Citations (Scopus)
168 Downloads (Pure)

Synthesis and characterisation of photocrosslinked poly(ethylene glycol) diacrylate
 implants for sustained ocular drug delivery

McAvoy, K., Jones, D. & Thakur, R. R. S., Feb 2018, In : Pharmaceutical Research. 35, 2, 17 p., 36.

Research output: Contribution to journal › Article

Open Access
File
19 Citations (Scopus)
281 Downloads (Pure)
2017

A new method of constructing drug-polymer temperature-composition phase diagram relevant to the hot-melt extrusion platform

Tian, Y., Jones, D., Donnelly, C., Brannigan, T., Li, S. & Andrews, G., 05 Dec 2017, In : Molecular Pharmaceutics. p. 1-39

Research output: Contribution to journal › Article

Open Access
File
6 Citations (Scopus)
264 Downloads (Pure)

Mechanochemical Synthesis of Pharmaceutical Cocrystal Suspensions via Hot Melt Extrusion: Enhancing Cocrystal Yield

Li, S., Yu, T., Tian, Y., Lagan, C., Jones, D. & Andrews, G., 22 Nov 2017, In : Molecular Pharmaceutics. 15, 9, p. 3741-3754

Research output: Contribution to journal › Article

Open Access
File
7 Citations (Scopus)
213 Downloads (Pure)

Minimally invasive microneedles for ocular drug delivery

Thakur, R., Tekko, I., McAvoy, K., Donnelly, R. F., McMillian, H. & Jones, D., Apr 2017, In : Expert Opinion on Drug Delivery. 14, 4, p. 525-537 13 p.

Research output: Contribution to journal › Article

Open Access
File
20 Citations (Scopus)
787 Downloads (Pure)

Photochemically controlled drug dosing from a polymeric scaffold

Donnelly, L., Hardy, J. G., Gorman, S. P., Jones, D. S., Irwin, N. J. & McCoy, C. P., 15 May 2017, In : Molecular Pharmaceutics. 8 p.

Research output: Contribution to journal › Article

Open Access
File
2 Citations (Scopus)
206 Downloads (Pure)

Posterior drug delivery via periocular route: challenges and opportunities

Waite, D., Wang, Y., Jones, D., Stitt, A. & Thakur, R., 01 Jul 2017, In : Therapeutic Delivery. 8, 8, p. 685-699 15 p.

Research output: Contribution to journal › Article

Open Access
File
13 Citations (Scopus)
276 Downloads (Pure)
2016

An infection-responsive approach to reduce bacterial adhesion in urinary biomaterials

McCoy, C. P., Irwin, N. J., Brady, C., Jones, D. S., Carson, L., Andrews, G. P. & Gorman, S. P., 2016, In : Molecular Pharmaceutics. 13, 8, p. 2817–2822 6 p.

Research output: Contribution to journal › Article

Open Access
File
16 Citations (Scopus)
249 Downloads (Pure)

Design of binary polymeric systems containing ɩ-carrageenan and hydroxypropylcellulose for use in cataract surgery.

Jones, D. S., Rafferty, G. P. & Andrews, G. P., 14 Jun 2016, In : Carbohydrate Polymers.

Research output: Contribution to journal › Article

Open Access
File
2 Citations (Scopus)
136 Downloads (Pure)

Mechanochemical Synthesis of Pharmaceutical Cocrystal Suspensions via Hot Melt Extrusion: Feasibility Studies and Physicochemical Characterisation

Li, S., Yu, T., Tian, Y., McCoy, C. P., Jones, D. S. & Andrews, G. P., 2016, In : Molecular Pharmaceutics. 13, 9, p. 3054–3068 15 p.

Research output: Contribution to journal › Article

Open Access
File
43 Citations (Scopus)
837 Downloads (Pure)

Optimising drug solubilisation in amorphous polymer dispersions: rational selection of hot-melt extrusion processing parameters

Li, S., Tian, Y., Jones, D. S. & Andrews, G. P., Feb 2016, In : AAPS PharmSciTech. 17, 1, p. 200-213

Research output: Contribution to journal › Article

14 Citations (Scopus)

Solubility parameter based screening methods for early stage formulation development of itraconazole amorphous solid dispersions

Piccinni, P., Tian, Y., McNaughton, A., Li, S., Fraser, J., Jones, D., Brown, S. & Andrews, G., May 2016, In : Journal of Pharmacy and Pharmacology. 68, 5, p. 705-720

Research output: Contribution to journal › Article

19 Citations (Scopus)

Statistical modelling of the rheological and mucoadhesive properties of aqueous poly(methylvinylether-co-maleic acid) networks: Redefining biomedical applications and the relationship between viscoelasticity and mucoadhesion

Jones, D. S., Lafferty, T. P., Morris, C. & Andrews, G. P., 01 Aug 2016, In : COLLOIDS AND SURFACES B-BIOINTERFACES. 144, p. 125-134 10 p.

Research output: Contribution to journal › Article

Open Access
File
15 Citations (Scopus)
169 Downloads (Pure)

The use of binary polymeric networks in stabilising polyethylene oxide solid dispersions

Jones, D. S., Tian, Y., Li, S., Yu, T., Abu Diak, O. A. & Andrews, G. P., Oct 2016, In : Journal of Pharmaceutical Sciences. 105, 10, p. 3064–3072

Research output: Contribution to journal › Article

Open Access
File
6 Citations (Scopus)
279 Downloads (Pure)
2015

An Investigation into the Role of Polymeric Carriers on Crystal Growth within Amorphous Solid Dispersion Systems

Tian, Y., Jones, D. S. & Andrews, G. P., 2015, In : Molecular Pharmaceutics. 12, 4, p. 1180-1192 13 p.

Research output: Contribution to journal › Article

23 Citations (Scopus)

Antimicrobial Efficacy of an Innovative Emulsion of Medium Chain Triglycerides against Canine and Feline Periodontopathogens

Laverty, G., Gilmore, B. F., Jones, D. S., Coyle, L., Folan, M. & Breathnach, R., Apr 2015, In : Journal of Small Animal Practice. 56, 4, p. 253-263 11 p.

Research output: Contribution to journal › Article

Open Access
File
2 Citations (Scopus)
428 Downloads (Pure)

Characterisation and modelling of the thermorheological properties of pharmaceutical polymers and their blends using capillary rheometry: Implications for hot melt processing of dosage forms.

Jones, D. S., Margetson, D. N., McAllister, M. S. & Andrews, G. P., 30 Sep 2015, In : International Journal of Pharmaceutics. 493, 1-2, p. 251-259 9 p.

Research output: Contribution to journal › Article

7 Citations (Scopus)

Comparative Study of Different Methods for the Prediction of Drug− Polymer Solubility

Knopp, M. M., Tajber, L., Tian, Y., Olesen, N. E., Jones, D. S., Kozyra, A., Lobmann, K., Paluch, K., Brennan, C. M., Holm, R., Healy, A. M., Andrews, G. P. & Rades, T., 08 Sep 2015, In : Molecular Pharmaceutics. 12, 9, p. 3408-3419 12 p.

Research output: Contribution to journal › Article

53 Citations (Scopus)

Hydrogel antimicrobial capture coatings for endotracheal tubes; a pharmaceutical strategy designed to prevent ventilator-associated pneumonia.

Jones, D. S., McCoy, C. P., Andrews, G. P., McCrory, R. M. & Gorman, S. P., 2015, In : Molecular Pharmaceutics. 12, 8, p. 2928-2936 9 p.

Research output: Contribution to journal › Article

Open Access
File
6 Citations (Scopus)
237 Downloads (Pure)

Hydrogel-Forming Microneedle Arrays Allow Detection of Drugs and Glucose In Vivo: Potential for Use in Diagnosis and Therapeutic Drug Monitoring

Caffarel-Salvador, E., Brady, A. J., Eltayib, E., Meng, T., Alonso-Vicente, A., Gonzalez-Vazquez, P., Torrisi, B. M., Vicente-Perez, E. M., Mooney, K., Jones, D. S., Bell, S. E. J., McCoy, C. P., McCarthy, H. O., McElnay, J. C. & Donnelly, R. F., 30 Dec 2015, In : PloS one. 10, 12, 21 p., e0145644.

Research output: Contribution to journal › Article

Open Access
File
45 Citations (Scopus)
519 Downloads (Pure)

Novel Supercritical Carbon Dioxide Impregnation Technique for the Production of Amorphous Solid Drug Dispersions: A Comparison to Hot Melt Extrusion

Potter, C., Tian, Y., Walker, G., McCoy, C., Hornsby, P., Donnelly, C., Jones, D. S. & Andrews, G. P., 31 Mar 2015, In : Molecular Pharmaceutics. 12, 5, p. 1377-1390 14 p.

Research output: Contribution to journal › Article

29 Citations (Scopus)

Probing The effects of Experimental Conditions on the Character of Drug-Polymer Phase Diagrams Constructed Using Flory-Huggins Theory

Donnelly, C., Tian, Y., Potter, C., Jones, D. S. & Andrews, G. P., Jan 2015, In : Pharmaceutical Research. 32, 1, p. 167-179 23 p.

Research output: Contribution to journal › Article

39 Citations (Scopus)

Punctal plug: a medical device to treat dry eye syndrome and for sustained drug delivery to the eye

Yellepeddi, V. K., Sheshala, R., McMillan, H., Gujral, C., Jones, D. & Singh, T. R. R., Jul 2015, In : Drug Discovery Today. 20, 7, p. 884-889 6 p.

Research output: Contribution to journal › Article

Open Access
File
21 Citations (Scopus)
387 Downloads (Pure)

Quantification of singlet oxygen generation from photodynamic hydrogels

Craig, R. A., McCoy, C. P., De Baroid, A. T., Andrews, G. P., Gorman, S. P. & Jones, D. S., Feb 2015, In : Reactive and Functional Polymers. 87, p. 1-6 6 p.

Research output: Contribution to journal › Article

Open Access
File
12 Citations (Scopus)
746 Downloads (Pure)

Rheological analysis of polymer interactions and ageing of poly(methylvinylether-co-maleic anhydride/poly(vinyl alcohol) binary networks and their effects on mucoadhesion

Jones, D., Laverty, T. & Andrews, G. P., Dec 2015, In : Journal of Pharmaceutical Sciences. 104, 12, p. 4329-4338 10 p.

Research output: Contribution to journal › Article

6 Citations (Scopus)
2014

Efficient Drug Delivery and Induction of Apoptosis in Colorectal Tumors Using a Death Receptor 5-Targeted Nanomedicine

Schmid, D., Fay, F., Small, D. M., Jaworski, J., Riley, J. S., Tegazzini, D., Fenning, C., Jones, D. S., Johnston, P. G., Longley, D. B. & Scott, C. J., Dec 2014, In : Molecular therapy : the journal of the American Society of Gene Therapy. 22, 12, p. 2083-2092 10 p.

Research output: Contribution to journal › Article

Open Access
File
21 Citations (Scopus)
313 Downloads (Pure)

Gastroretentive Extended-Release Floating Granules Prepared Using a Novel Fluidized Hot Melt Granulation (FHMG) Technique

Zhai, H., Jones, D. S., McCoy, C. P., Madi, A. M., Tian, Y. & Andrews, G. P., Oct 2014, In : Molecular Pharmaceutics. 11, 10, p. 3471-3483 13 p.

Research output: Contribution to journal › Article

9 Citations (Scopus)

Photodynamic antimicrobial polymers for infection control

McCoy, C. P., O'Neil, E. J., Cowley, J. F., Carson, L., De Baróid, A. T., Gdowski, G. T., Gorman, S. P. & Jones, D. S., Sep 2014, In : PloS one. 9, 9, e108500.

Research output: Contribution to journal › Article

Open Access
File
17 Citations (Scopus)
326 Downloads (Pure)

Solvent induced phase inversion-based in situ forming controlled release drug delivery implants

Thakur, R. R. S., McMillan, H. L. & Jones, D. S., 28 Feb 2014, In : Journal of Controlled Release. 176, p. 8-23 16 p.

Research output: Contribution to journal › Article

53 Citations (Scopus)

The rheological characterisation of emulsions as saliva substitutes.

Hanning, S., Yu, T., Kieser, J., Andrews, G., Jones, D. & Medlicott, N., 2014, In : Annual Transactions of the Nordic Rheology Society. 22, p. 87-94

Research output: Contribution to journal › Article

Thermodynamically stable amorphous drug dispersions in amorphous hydrophilic polymers engineered by hot melt extrusion.

Jones, D. S., Margetson, D. N., McAllister, M. S., Yu, T., Shu, L., McCoy, C. P. & Andrews, G. P., Dec 2014, In : Chemical Engineering Research and Design. 92, 12, p. 3046-3054 9 p.

Research output: Contribution to journal › Article

7 Citations (Scopus)

Ultrashort Cationic Naphthalene-Derived Self-Assembled Peptides as Antimicrobial Nanomaterials

Laverty, G., McCloskey, A. P., Gilmore, B. F., Jones, D. S., Zhou, J. & Xu, B., 08 Sep 2014, In : Biomacromolecules. 15, 9, p. 3429 − 3439 11 p.

Research output: Contribution to journal › Article

Open Access
File
47 Citations (Scopus)
462 Downloads (Pure)

Using debate to teach pharmacy students about ethical issues

Hanna, L-A., Barry, J., Donnelly, R., Hughes, F., Jones, D., Laverty, G., Parsons, C. & Ryan, C., 17 Apr 2014, In : American Journal of Pharmaceutical Education. 78, 3, p. 1-8 8 p., 57.

Research output: Contribution to journal › Article

22 Citations (Scopus)

Using Flory-Huggins phase diagrams as a pre-formulation tool for the production of amorphous solid dispersions; a comparison between hot-melt extrusion and spray drying

Tian, Y., Caron, V., Jones, D. S., Healy, A-M. & Andrews, G. P., Feb 2014, In : Journal of Pharmacy and Pharmacology. 66, 2, p. 256-274 19 p.

Research output: Contribution to journal › Article

46 Citations (Scopus)
2013

Construction of Drug–Polymer Thermodynamic Phase Diagrams Using Flory–Huggins Interaction Theory: Identifying the Relevance of Temperature and Drug Weight Fraction to Phase Separation within Solid Dispersions

Tian, Y., Booth, J., Meehan, E., Jones, D. S., Li, S. & Andrews, G. P., 2013, In : Molecular Pharmaceutics. 10, 1, p. 236-248 13 p.

Research output: Contribution to journal › Article

124 Citations (Scopus)

Electrical methods of controlling bacterial adhesion and biofilm on device surfaces.

Freebairn, D., Linton, D., Harkin-Jones, E., Jones, D. S., Gilmore, B. F. & Gorman, S. P., 2013, In : Expert review of medical devices. 10, 1, p. 85-103 19 p.

Research output: Contribution to journal › Article

File
22 Citations (Scopus)
1137 Downloads (Pure)