David Woolfson

Professor

1986 …2016

Research output per year

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Personal profile

Interests

Professor David Woolfson holds the Chair in Pharmaceutics (Drug Delivery). He is a graduate in Pharmacy from Queen's and is a registered pharmacist. Prof. Woolfson founded the McClay Research Centre for Pharmaceutical Sciences, from initial concept through to raising of the necessary funding. Starting as a lecturer in pharmaceutical analysis, he was appointed Reader in Pharmaceutical Sciences in 1991 and to the Chair in Pharmaceutics in 1995. He is Head of the School of Pharmacy at Queen's.

Prof. Woolfson became a member of the British Pharmacopoeia Commission (BPC) in 1997 and was appointed as Chair of the BPC in 2006. The Commission is responsible under the UK Medicines Act for the annual publication of the British Pharmacopoeia., which sets legally enforceable quality standards for medicinal chemicals, drugs and formulated products. He has extensive experience of work in the European Pharmacopoeia Commission (EPC) as leader of the UK delegation and formerly UK Expert on Formulated Medicinal Products. He is a member of the Editorial Advisory Board of CRC Books Inc. and formerly of the Scientific Advisory Board of the International Partnership for Microbicides. He has published 3 books, approximately 300 scientific publications, holds several patents on drug delivery systems and biomaterials and has given numerous invited conference presentations.

Research Statement

Prof. Woolfson's research interests are in polymeric drug delivery systems for transdermal and intravaginal applications, bioadhesion and biomaterials. The emphasis is on facilitated controlled drug delivery through challenging polymeric systems, where physicochemical aspects (drug molecular size, solubility or stability, polymer system tortuosity and relative hydrophobicity) present difficulties to efficient drug release. The current focus is on novel polymeric systems for transdermal delivery, vaginal delivery of HIV microbicides and the development of vaginally deliveryed HIV mucosal vaccines. Key achievements include the invention of the marketed percutaneous local anaesthetic product Ametop, and contributions to the development of several other pharmaceuticals, including the vaginal ring HRT product Femring. The research programmes are funded from a range of sources including UK Research Councils, major charities such as the Bill and Melinda Gates Foundation and the Wellcome Trust, the International Partnership for Microbicides and other charities for the prevention of HIV, and the Pharmaceutical Industry. Prof. Woolfson's career research grants to date total £17M.

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Projects

Research Output

A facile system to evaluate in vitro drug release from dissolving microneedle arrays

Larrañeta, E., Stewart, S., Fallows, S. J., Birkhäuer, L. L., McCrudden, M. T. C., Woolfson, A. D. & Donnelly, R. F., 30 Jan 2016, In : International Journal of Pharmaceutics. 497, 1-2, p. 62-69 8 p.

Research output: Contribution to journalArticle

Open Access
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  • 18 Citations (Scopus)
    406 Downloads (Pure)
    Open Access
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  • 143 Citations (Scopus)
    1132 Downloads (Pure)
    Open Access
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  • 32 Citations (Scopus)
    733 Downloads (Pure)

    Considerations in the sterile manufacture of polymeric microneedle arrays

    McCrudden, M. T. C., Zaid Alkilani, A., Courtenay, A., McCrudden, C. M., McCloskey, B., Walker, C., Alshraiedeh, N., Lutton, R. E. M., Gilmore, B. F., Woolfson, A. D. & Donnelly, R. F., Feb 2015, In : Drug Delivery and Translational Research. 5, 1, p. 3-14 12 p.

    Research output: Contribution to journalArticle

  • 39 Citations (Scopus)
    Open Access
    File
  • 27 Citations (Scopus)
    1529 Downloads (Pure)

    Prizes

    Elected Fellow

    David Woolfson (Recipient), 1989

    Prize: Election to learned society

    Elected Fellow of the Pharmaceutical Society NI

    David Woolfson (Recipient), 2009

    Prize: Fellowship awarded competitively

    Activities

    CRC Press (External organisation)

    David Woolfson (Member)
    20102012

    Activity: Membership typesMembership of peer review panel or committee

    Pharmaceutical Society of Northern Ireland (External organisation)

    David Woolfson (Member)
    20102012

    Activity: Membership typesMembership of peer review panel or committee

    China Medical University

    David Woolfson (Visitor)
    2010 → …

    Activity: Visiting an external institution typesResearch and Teaching at External Organisation

    Pharmaceutical Society of Northern Ireland (External organisation)

    David Woolfson (Member)
    20092012

    Activity: Membership typesMembership of external research organisation

    Council of University Heads of Pharmacy Schools (External organisation)

    David Woolfson (Member)
    2009 → …

    Activity: Membership typesMembership of external research organisation

    Impact

    Protecting Women from HIV AIDS: Dapivirine Vaginal Ring HIV Microbicide

    David Woolfson (Participant), Karl Malcolm (Participant), Stephen McCullagh (Participant), Martin Catney (Participant)

    Impact: Health Impact