Projects per year
Personal profile
Research Statement
My research is centred on using data to better understand the most common causes of vision loss.
Developing Machine Learning pipelines for ophthalmic data
A major strand of my work is a deeper exploration of ophthalmic data from the Northern Ireland Cohort for the Longitudinal study of Ageing (NICOLA) using cutting-edge data science techniques. I am interested in the use of ensemble models to flexibly model tabular data and interpretable Machine Learning techniques to separate signal from noise.
Large scale analysis of Electronic Medical Records
I am analysing two large datasets of anonymised electronic medical records.
The first is a study into the use of machine learning to identify factors associated with long term response to wet AMD treatment, using records of ~4500 patients over a 12 year period.
The second is a multi-centre health technology assessment funded by the National Institute for Health Research, using records from ~13,000 patients to predict risk of conversion from ocular hypertension to glaucoma.
Teaching
Undergraduate
Module Co-ordinator and Lecturer - "The rise of Artificial Intelligence in healthcare" (3rd Year Medicine)
Personal tutor and Portfolio adviser to 12 undergraduate Medical students
Statistics practical classes (Bio-Medical Sciences)
Postgraduate
R programming (Bioinformatics, Research Skills in Experimental Medicine)
Statistics practical classes (Medical Statistics)
PhD Supervision
Benedict Leonard-Hawkhead (1st Supervisor)
Hannah Griffin (2nd Supervisor)
MD Supervision
John Smith (3rd Supervisor)
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Collaborations and top research areas from the last five years
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R2806CPH: A Suite of Studies Exploring the Impact of Vision Care on Achieving the Sustainable Development Goals in Low and Middle-Income Countries
Congdon, N. (PI), Azuara-Blanco, A. (CoI), Chan, V. F. (CoI), Clarke, M. (CoI), Hogg, R. (CoI), Lohfeld, L. (CoI), Murphy, J. (CoI), O'Neill, C. (CoI) & Wright, D. (CoI)
05/08/2021 → …
Project: Research
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R2733CPH: Using data science to determine the best combination of factors for the diagnosis of AMD and to detect clinical change over time
Hogg, R. (PI), Hua, Y. (CoI), Kee, F. (CoI), Lengyel, I. (CoI), McKnight, A. J. (CoI), Sousa, J. (CoI) & Wright, D. (CoI)
03/08/2020 → …
Project: Research
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R1870CPH: Data driven public health approaches for diabetic retinopathy and age-related macular degeneration
Wright, D. (PI), Lawler, M. (CoI) & O'Reilly, D. (CoI)
27/03/2018 → …
Project: Research
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R3195CPH: Algorithms for diagnosis and management of age related macular degeneration. Lay title: Can computers help with making the best decision for diagnosis and treatment of ageing eye disease
Peto, T. (PI) & Wright, D. (CoI)
21/01/2020 → 30/04/2024
Project: Research
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Cost-effectiveness of monitoring ocular hypertension based on a risk prediction tool
Wu, H., Gazzard, G., King, A., Morgan, J., Wright, D., Crabb, D. P., Takwoingi, Y., Azuara-Blanco, A., Watson, V. & Hernández, R., 28 Aug 2024, In: BMJ Open Ophthalmology. 9, 1, e001741.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Downloads (Pure) -
Estimating the distribution of true rates of visual field progression in glaucoma
Montesano, G., Crabb, D. P., Wright, D. M., Rabiolo, A., Ometto, G. & Garway-Heath, D. F., 09 Apr 2024, In: Translational Vision Science & Technology. 13, 4, 19 p., 15.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)12 Downloads (Pure) -
Face-down positioning or posturing after pars plana vitrectomy for macula-involving rhegmatogenous retinal detachments
Fung, T. H., Yim, T. W., Lois, N., Wright, D. M., Liu, S. H. & Williamson, T., 15 Mar 2024, In: Cochrane Database of Systematic Reviews. 2024, 3, 46 p., CD015514.Research output: Contribution to journal › Review article › peer-review
1 Citation (Scopus) -
The double layer sign is highly predictive of progression to exudation in age-related macular degeneration
Csincsik, L., Muldrew, K. A., Bettiol, A., Wright, D. M., Rosenfeld, P. J., Waheed, N. K., Empeslidis, T., De Cock, E., Yamaguchi, T. C. N., Hogg, R. E., Peto, T. & Chakravarthy, U., Mar 2024, In: Opthalmology Retina. 8, 3, p. 234-245 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)33 Downloads (Pure) -
Using deep learning transformer models to genotype/phenotype relationships in age-related macular degeneration (AMD) in NICOLA
Haider, A., Gault, R., Hogg, R., Wright, D., Peto, T. & Wang, H., 23 Sept 2024, (Accepted).Research output: Contribution to conference › Poster › peer-review
File10 Downloads (Pure)
Activities
- 1 Public lecture/debate/seminar
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Stormont Assembly Knowledge Exchange Seminar - Economic Opportunities, Occupational Class Status and Social Mobility in Northern Ireland:
Moriarty, J. (Invited speaker), Wright, D. (Contributor), O'Reilly, D. (Contributor) & Thurston, A. (Contributor)
25 Jan 2017Activity: Talk or presentation types › Public lecture/debate/seminar