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Personal profile

Research Interests

  • Mesenchymal stem cell therapy for the treatment of chronic lung diseases
  • Molecular charaterisation of liver disease caused by alpha-1-antitrypsin deficiency

Fingerprint Dive into the research topics where Declan Doherty is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 7 Similar Profiles
cathepsin S Medicine & Life Sciences
Calcitriol Receptors Medicine & Life Sciences
Cytochrome P-450 CYP3A Medicine & Life Sciences
Lung Medicine & Life Sciences
Lung Diseases Medicine & Life Sciences
Mesenchymal Stromal Cells Medicine & Life Sciences
Androgens Medicine & Life Sciences
SUMO-1 Protein Medicine & Life Sciences

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Research Output 2011 2019

Lack of IL-1 Receptor Signaling Reduces Spontaneous Airway Eosinophilia in Juvenile Mice with Muco-Obstructive Lung Disease

Brown, R., Paulsen, M., Schmidt, S., Schaterrny, J., Frank, A., Hirtz, S., Delaney, R., Doherty, D., Hagner, M., Taggart, C., Weldon, S. & Mall, M. A., 09 Sep 2019, In : American Journal of Respiratory Cell and Molecular Biology.

Research output: Contribution to journalArticle

Obstructive Lung Diseases
Pulmonary diseases
Interleukin-1 Receptors
3 Citations (Scopus)
212 Downloads (Pure)

Protein Phosphatase 2A Reduces Cigarette Smoke-Induced Cathepsin S and Loss of Lung Function

Doherty, D. F., Nath, S., Poon, J., Foronjy, R. F., Ohlmeyer, M., Dabo, A. J., Salathe, M., Birrell, M., Belvisi, M., Baumlin, N., Kim, M. D., Weldon, S., Taggart, C. & Geraghty, P., 14 Jan 2019, In : American Journal of Respiratory and Critical Care Medicine.

Research output: Contribution to journalArticle

Open Access
cathepsin S
Protein Phosphatase 2
Tobacco Products
Chronic Obstructive Pulmonary Disease
2 Citations (Scopus)

Targeting of Cathepsin S Reduces Cystic Fibrosis-like Lung Disease

Small, D. M., Brown, R. R., Doherty, D. F., Abladey, A., Zhou- Suckow, Z., Delaney, R. J., Kerrigan, L., Dougan, C. M., Borensztajn, K. S., Holsinger, L., Booth, R., Scott, C. J., Lopez Campos, G., Elborn, J. S., Mall, M. A., Weldon, S. & Taggart, C. C., 28 Mar 2019, In : European Respiratory Journal. 53, 3, 1801523.

Research output: Contribution to journalArticle

cathepsin S
Cystic Fibrosis
Lung Diseases
Epithelial Sodium Channels
2 Citations (Scopus)
100 Downloads (Pure)

Characterisation of eppin function: expression and activity in the lung

Scott, A., Glasgow, A., Small, D., Carlile, S., McCrudden, M., McLean, D., Brown, R., Doherty, D., Lundy, F., Hamid, U., O'Kane, C., McAuley, D., Brodlie, M., Tunney, M., Elborn, J., Irwin, C., Timson, D., Taggart, C. & Weldon, S., 13 Jul 2017, In : European Respiratory Journal. 50, 1, 1601937.

Research output: Contribution to journalArticle

Open Access
Myeloid Cells
Chemokine CXCL2
Serine Proteinase Inhibitors
Neutrophil Infiltration
2 Citations (Scopus)
284 Downloads (Pure)

The Role of Whey Acidic Protein Four-Disulfide-Core Proteins in Respiratory Health and Disease

Small, D. M., Doherty, D. F., Dougan, C. M., Weldon, S. & Taggart, C. C., 01 Apr 2017, In : Biological Chemistry. 398, 3, p. 425-440

Research output: Contribution to journalReview article

Open Access
Secretory Leukocyte Peptidase Inhibitor