20062021

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https://www.facebook.com/TheFitzgeraldGroup1/

Research Statement

The Fitzgerald lab is a Regenerative NeuroImmunology research group at QUB with a particular focus on Multiple Sclerosis (MS), an immune-mediated, demyelinating disorder of the Central Nervous System (CNS).  The central goal of our research is to identify new strategies to treat MS and other inflammatory and demyelinating disorders.

We are particularly interested in the process of myelin regeneration (remyelination) and aim to identify novel therapeutic targets to promote remyelination in MS. To do this, we are uncovering new knowledge of how the immune system influences tissue regeneration in the Central Nervous System (CNS). We also conduct a research programme on the pathogenesis of autoimmune inflammation. This programme mainly focuses on T cell biology with a view to identifying strategies to reduce disease activity in MS and other immune-mediated diseases. Previous work investigated the fundamental biology of IL-27 and its therapeutic potential in inflammatory/autoimmune disease, with particular focus on Th1- and Th17-mediated inflammatory responses.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

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