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20082019
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Personal profile

Research Statement

Dimitrios A. Lamprou (Ph.D., MBA) is Reader in Pharmaceutical Engineering (May 2018 – Present) and Programme Director at MSc in Industrial Pharmaceutics at School of Pharmacy in Queen's University Belfast (UK), and Visiting Researcher (Sep 2016 – Present) at University of Strathclyde (Glasgow, UK). Prior to his current appointments, Dimitrios was Senior Lecturer in Pharmaceutics & Drug Delivery (Sep 2016 – Apr 2018) at University of Kent (UK), Lecturer B in Pharmaceutical Sciences (Aug 2012 Aug 2016) and Postdoctoral Fellow in Biomaterials and Drug Delivery Systems (Oct 2009 Jul 2012) at Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS) at University of Strathclyde (UK). Dimitrios was also Visiting Scientist at Massachusetts Institute of Technology (MIT Center for Biomedical Engineering; US) in 2010 and at Aristotle University of Thessaloniki (Department of Pharmaceutical Technology; Greece) in 2011. Dimitrios has experience of teaching (including MPharm & MSc accreditations, and preparing 2 de novo Master's degree programmes) in Higher Education (Pharmacy Departments in UK) since Oct 2006, conducting research and securing National (e.g. EPSRC, SULSA) and International (e.g. HORIZON 2020, Commonwealth) Funding (Over £2M) as Co-I or PI, and is currently involved in a variety of industry projects and collaborates with academic partners and clinicians within the UK and internationally. He is Committee Member (Secretary: Sep 2017 – Present) at the United Kingdom and Ireland Controlled Release Society (UKICRS) since Oct 2013, has examined over 20 Ph.D. Thesis in UK and for International Institutions (e.g. in India and Italy), and referees for journals (50+ Pharmaceutical and related; Impact Factor: 3 to 15) and publishers (e.g. Elsevier), and for 10+ research funding bodies internationally (e.g. Hungary) and nationally (e.g. BBSRC, EPSRC, MRC). Dimitrios, since 2008 has authored over 70 articles in high impact multidisciplinary journals, over 200 conference abstracts and over 80 Oral/Invited presentations. Dimitrios has experience of supervising as PI or Co-I Post-Doc's, over 100 Undergraduate and Postgraduate Project students (e.g. Erasmus, MChem, MPharm, MPhil, MRes, MSc) and over 15 Ph.D. students to successful completion (< 4 years), all of whom are now further developing their careers in either Academic or Industrial positions. Dimitrios is Editorial Board Member for 3 Refereed Journals (e.g. Pharmaceutics, Heliyon) and Guest Editor for 7 Special Issues in International Refereed Journals. Dimitrios research and academic leadership has been recognised in a range of awards including the Royal Pharmaceutical Society (RPS) Science Award (2017) and the Scottish Universities Life Sciences Alliance (SULSA) Leaders Scheme Award (2013).

Achievements

Academic / Professional Qualifications: Dimitrios was trained in multi-disciplinary areas and in first class laboratories (e.g. in Greece, UK, USA). He received Bachelor's BEng (Hons) degree in Medical Engineering from the University of Bradford (UK), Master's in Biomedical Engineering from the University of Surrey (UK), working on Tissue Engineered Vascular Grafts, and Ph.D. in Bio-Surface Chemistry (Ph.D. Thesis Viva took place in Nov 2009) in a collaborative project between the University of Portsmouth (UK) and the Defence Science and Technology Laboratory (Dstl) - Porton Down (UK), by working in areas such as biomaterials, bioadhesion and drug delivery. Also holds Certificate in Computing (with experience in chemometrics using PCA/PLS and other multivariate approaches), PgCert in Scientific Research Methods for Laboratory Scientists from the University of Portsmouth (UK), PgDip in Advanced Academic Studies from the University of Strathclyde (UK) and Master of Business Administration (MBA) from Middlesex University (UK). Dimitrios has also participated in numerous workshops, seminars and courses about management, leadership, marketing, teaching, and has gain advance experience in a range of research techniques.

Research Interests

· Our research group focus is towards the successful delivery of therapeutic agents in a controlled and targeted manner and the development of advanced delivery systems for a variety of applications.

· Our ambition is to pursue the most exciting, challenging, up-to-date and hot topics in the area of Pharmaceutical Science & Technology.

· We are applying aspects of Pharmaceutical Technology to a range of areas such as cancer, antimicrobial resistance and nanomedicine development.

· Our research involves both the study of material characteristics as well as the application of such knowledge to the design and manufacture of pharmaceutical products including the implementation of concepts such as Quality by Design (QbD) & Process Analytical Technology (PAT), and the use of state-of-the-art Nanocharacterisation Techniques (e.g. AFM, μCT, ToF-SIMS).

We are applying Nano and Microfabrication Techniques in Pharmaceutical and Medical Device Manufacturing. More specifically, our areas of interest include:

1) Additive Manufacturing (AM): a) Manufacturing of drug delivery systems & medical devices (e.g. catheters, meshes, microneedles, tablets) using innovative 3D printing technologies. Including in-house prepared filaments by hot-melt extrusion (HME) and granules/pellets by Twin Screw Granulation (TSG). b) 3D Bioprinting applications in pharmaceutics and tissue engineering. Including the use of Microelectromechanical Systems (MEMS) devices to control the drug dosage.

2) Electrospinning (melt & solution): Manufacturing of nanofibers for a variety of drug delivery and tissue engineering applications (e.g. films, mesh implants, wound healing).

3) Microfluidics & Microfluidic Devices: a) Engineering of novel drug delivery systems (e.g. Lipid & Polymeric) using microfluidics and comparison with traditional formulation methods for imaging and treatment/targeting using new or currently available anticancer, antidiabetic and anti-infective drugs. b) In-house fabrication of microfluidic chips by 3D printing and soft photolithography.

Our studies include: formulation, physicochemical characterization, computational modelling, and in vitro & in vivo evaluation.

Teaching

• Teaching on the Pharmacy MPharm Degree, on the BSc in Pharmaceutical Sciences, and on the MSc in Industrial Pharmaceutics. Teaching Modules included: Applied Pharmaceutical Analysis, Formulation of Pharmaceutical & Biopharmaceutical Products, Leadership & Project Management, Medicines from Concept to Clinic, Medicinal Substances: Characterisation and Quantification, Pharmaceutical Manufacturing & Emerging Technologies, and Quality Assurance & Regulatory Affairs.

 Supporting the School with teaching in the China Queen's College (CQC), couple of weeks per year. Lecture topics in the areas of Industrial Biotechnology and Quality Assurance & Regulatory Aspects.

Other

· Mentor.

· School of Pharmacy Research Excellence Framework (REF) Reading Group Member.

· Research Committee Member in the School of Pharmacy.

· School of Pharmacy Athena SWAN Self-Assessment Team (SAT) Member.

· Member of the School of Pharmacy Internationalisation Committee.

· Assist the School of Pharmacy in Career Events and Open Days.

· Member of the Material and Advanced Technologies for Healthcare (MATCH) interdisciplinary research initiative.

Fingerprint Dive into the research topics where Dimitrios Lamprou is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Nanoparticles Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
Polymers Chemical Compounds
Atomic force microscopy Chemical Compounds
gemcitabine Medicine & Life Sciences
Hydrogels Chemical Compounds
Particle Size Medicine & Life Sciences
Liposomes Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2008 2019

1 Citation (Scopus)

3D printed microneedle patches using stereolithography (SLA) for intradermal insulin delivery

Economidou, S. N., Pere, C. P. P., Reid, A., Uddin, M. J., Windmill, J. F. C., Lamprou, D. & Douroumis, D., 22 Apr 2019, In : Materials Science and Engineering C: Materials for Biological Applications.

Research output: Contribution to journalArticle

Stereolithography
insulin
Insulin
delivery
lithography
2 Citations (Scopus)

Biological Performance of Electrospun Polymer Fibres

Hall Barrientos, I. J., MacKenzie, G. R., Wilson, C. G., Lamprou, D. A. & Coats, P., 24 Jan 2019, In : Materials. 12, 3, 13 p., 363.

Research output: Contribution to journalArticle

Open Access
File
Scaffolds
Polymers
Collagen
Polycaprolactone
Cell adhesion
Dialysis
Catheters
Tetracycline
Fabrication
3D printers
dialysis
Dialysis
Catheters
infectious diseases
manufacturing
Equipment and Supplies
Pharmaceutical Preparations
Therapeutics
Drug Delivery Systems

Prizes

Royal Pharmaceutical Society (RPS) Science Award 2017

Dimitrios Lamprou (Recipient), Sep 2017

Prize: Prize (including medals and awards)

drug
industry
science

Scottish Universities Life Sciences Alliance (SULSA) Leaders Scheme Award

Dimitrios Lamprou (Recipient), 2013

Prize: Prize (including medals and awards)

Activities 2012 2020

3D Printed Delivery Systems for Drugs & Biologics

Dimitrios Lamprou (Invited speaker)
24 Mar 202026 Mar 2020

Activity: Talk or presentation typesInvited or keynote talk at national or international conference

China Medical University – Queen’s University Belfast Joint College

Dimitrios Lamprou (Visiting lecturer)
30 Mar 202003 Apr 2020

Activity: Visiting an external institution typesResearch and Teaching at External Organisation

United Kingdom and Ireland Controlled Release Society (External organisation)

Dimitrios Lamprou (Chair)
Jun 2020Jun 2023

Activity: Membership typesMembership of external research organisation

The 11th Academy of Pharmaceutical Sciences (APS) International PharmSci Conference 2020

Dimitrios Lamprou (Session chair)
Sep 2020

Activity: Participating in or organising an event typesParticipation in conference

Development of Injectable Intraperitoneal Sustained Release Drug Delivery System for Ovarian Cancer

Dimitrios Lamprou (Examiner)
28 Feb 2020

Activity: Examination typesPhD external examination