• Room 01.019 - Biological Sciences

    United Kingdom

Accepting PhD Students

20022019

Research output per year

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Research Output

2019

Gene Fusions derived by transcriptional readthrough are Driven by Segmental Duplication in Human

Am, M., Hyland, E. M., Cormican, P., Moran, R. J., Webb, A. E., Lee, K. D., Hernandez, J., Prado-Martinez, J., Creevey, C. J., Aspden, J. L., McInerney, J. O., Marques-Bonet, T. & Mj, OC., 01 Sep 2019, In : Genome biology and evolution. 11, 9, p. 2678–2690

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
56 Downloads (Pure)

Repurposing histone deacetylase inhibitors (HDACi) to treat Candida glabrata infections

O’Kane, C. J., Marshall, A., O’Connell, M. J. & Hyland, E. M., 08 Apr 2019, In : Access Microbiology. 1, 1A

Research output: Contribution to journalArticle

Open Access

Yeast Epigenetics: The Inheritance of Histone Modification States

O'Kane, C. J. & Hyland, E. M., 15 Mar 2019, In : Bioscience Reports.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
124 Downloads (Pure)
2018

Protein Synthesis and Turnover

Hyland, E. M., 27 Feb 2018, Medical Biochemistry. Baynes, J. & Dominiczak, M. (eds.). 5 ed. Elsevier, 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Regulation of Gene Expression: Basic Mechanisms

Hyland, E. M., 27 Feb 2018, Medical Biochemistry. Baynes, J. & Dominiczak, M. (eds.). 5 ed. USA: Elsevier, 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Yeast heterochromatin regulators Sir2 and Sir3 act directly at euchromatic DNA replication origins

Hoggard, T. A., Chang, F., Perry, K. R., Subramanian, S., Kenworthy, J., Chueng, J., Shor, E., Hyland, E. M., Boeke, J. D., Weinreich, M. & Fox, C. A., 24 May 2018, In : PLoS Genetics. 14, 5, p. e1007418 26 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
131 Downloads (Pure)
2017

Mining for ancient sirtuins in alpine paleosols

Mackle, J., Skvortsov, T., Allen, C. & Hyland, E. M., 2017.

Research output: Contribution to conferenceAbstract

2014

A Model for the Evolution of Biological Specificity: a Cross-Reacting DNA-Binding Protein Causes Plasmid Incompatibility

Hyland, E. M., Wallace, E. W. J. & Murray, A. W., 15 Aug 2014, In : Journal of Bacteriology. 196, 16, p. 3002-3011

Research output: Contribution to journalArticle

5 Citations (Scopus)
2011

An evolutionarily 'young' lysine residue in histone H3 attenuates transcriptional output in Saccharomyces cerevisiae

Hyland, E. M., Molina, H., Poorey, K., Jie, C., Xie, Z., Dai, J., Qian, J., Bekiranov, S., Auble, D. T., Pandey, A. & Boeke, J. D., 15 Jun 2011, In : Genes & development. 25, 12, p. 1306-19 14 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2010

Histone h3 exerts a key function in mitotic checkpoint control

Luo, J., Xu, X., Hall, H., Hyland, E. M., Boeke, J. D., Hazbun, T. & Kuo, M-H., Jan 2010, In : Molecular and Cellular Biology. 30, 2, p. 537-49 13 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Yin and Yang of histone H2B roles in silencing and longevity: a tale of two arginines

Dai, J., Hyland, E. M., Norris, A. & Boeke, J. D., Nov 2010, In : Genetics. 186, 3, p. 813-28 16 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2009

HistoneHits: a database for histone mutations and their phenotypes

Huang, H., Maertens, A. M., Hyland, E. M., Dai, J., Norris, A., Boeke, J. D. & Bader, J. S., Apr 2009, In : Genome Research. 19, 4, p. 674-81 8 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)
2008

Probing nucleosome function: a highly versatile library of synthetic histone H3 and H4 mutants

Dai, J., Hyland, E. M., Yuan, D. S., Huang, H., Bader, J. S. & Boeke, J. D., 19 Sep 2008, In : Cell. 134, 6, p. 1066-78 13 p.

Research output: Contribution to journalArticle

124 Citations (Scopus)
2005

Insights into the role of histone H3 and histone H4 core modifiable residues in Saccharomyces cerevisiae

Hyland, E. M., Cosgrove, M. S., Molina, H., Wang, D., Pandey, A., Cottee, R. J. & Boeke, J. D., Nov 2005, In : Molecular and Cellular Biology. 25, 22, p. 10060-70 11 p.

Research output: Contribution to journalArticle

158 Citations (Scopus)
2003

The DNA binding domain of the gene 2.5 single-stranded DNA-binding protein of bacteriophage T7

Hyland, E. M., Rezende, L. F. & Richardson, C. C., 28 Feb 2003, In : The Journal of biological chemistry. 278, 9, p. 7247-56 10 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)
2002

Caspase-3 is not essential for DNA fragmentation in MCF-7 cells during apoptosis induced by the pyrrolo-1,5-benzoxazepine, PBOX-6

Mc Gee, M. M., Hyland, E., Campiani, G., Ramunno, A., Nacci, V. & Zisterer, D. M., 27 Mar 2002, In : FEBS Letters. 515, 1-3, p. 66-70 5 p.

Research output: Contribution to journalArticle

83 Citations (Scopus)