Research output per year
Research output per year
Dr
Room 02.061 - CEM
United Kingdom
Accepting PhD Students
PhD projects
If you are interested in learning more about current research projects in the field epigenetics and working on my group, please do not hesitate to contact me: [email protected].
Research activity per year
I am a molecular biologist & geneticist specialized in epigenetics in cancer & leukaemia. I have been actively researching Chronic Lymphocytic Leukaemia as a fellow of Propondis Foundation with a focus on intraclonal diversity and immunogenetics. My research path includes work at the field of tumor immunology (T regulatory cells in melanoma and antitumor responses) as a Onassis fellow at German Cancer Research Center (DKFZ). Over the past years I have developed strong expertise and interest in the field of Epigenetics including DNA methylation & histone modifications research projects. As a research fellow at Heidelberg University and DKFZ I have investigated epigenetics mechanisms of HPV-related head neck squamous cell carcinomas and I have identified a novel epigenetic signature which can serve as a robust biomarker for patient stratification and treatment de-escallation.
Since 2018 I joined Queen’s University Belfast (School of Medicine, Dentistry and Biomedical Sciences - The Wellcome-Wolfson Institute for Experimental Medicine) where I lead a research group on Epigenetics with a focus on Leukaemia and Lymphocytes biology.
Understanding the molecular mechanisms underlying treatment failure in chronic diseases such as leukaemia is an essential biological question with important clinical impact. In the last years, we have performed high throughput characterization of the enhancer landscape in Chronic Lymphocytic Leukaemia upon BTK inhibitory treatment aiming at shedding lights into treatment resistance mechanisms beyond the well-described mutations. Next, our lab research mission is to:
MED1012: Personal and Professional Development Portfolio
MED 2018: Personal and Professional Development Portfolio
SCM8097-SCM8134: Immunity in Health and Disease (MSc Experimental Medicine)
SCM8108: Applied Genomics (MSc Bioinformatics and Computational Genomics)
BMS3104: Molecular Markers of Disease
BMS3112: The Research Project Module (Biomedical Sciences) (supervision)
SCM8146-Research Project and Dissertation (Msc Experimental Medicine) (supervision)
EDUCATIONAL RESEARCH INTERESTS
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Review article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to conference › Abstract › peer-review
Research output: Contribution to conference › Abstract › peer-review
Kostareli, E. (Recipient), 01 Apr 2019
Prize: Prize (including medals and awards)
Kostareli, E. (Speaker)
Activity: Other activity types › Other
Kostareli, E. (Contributor)
Activity: Membership types › Membership of network
Kostareli, E. (Invited speaker)
Activity: Talk or presentation types › Invited talk
Kostareli, E. (Meta-reviewer)
Activity: Participating in or organising an event types › Participation in conference
Kostareli, E. (Member)
Activity: Membership types › Membership of network