• Room 03.064 - CEM

    United Kingdom

Accepting PhD Students

PhD projects

Dr Beli is open to PhD applications from candidates with a basic science or clinical background. Areas of interest include: - Microbiota derived Metabolites in Vascular Physiology and Inflammation - Circadian Rhythms in long-term Diabetes Previous research experience is desirable although not essential.

20082020

Research output per year

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Personal profile

Research Focus

Living with diabetes has been made easier with insulin pumps and medications. However, the risk of developing complications remains high, and a diagnosis of diabetic retinopathy, the most common diabetic complication can be scary and confusing. Our laboratory is interested in the role of circadian rhythms in the progression of diabetic retinopathy, in chronotiming drug delivery and biomarker sampling and in designing non invasive lifestyle interventions to delay the onset of diabetic retinopathy.                                          

We are focused in studying physiological and systemic parameters affecting innate immunity and retinal health. We use type 1 and type 2 diabetic models and multi-omics approaches to identify metablic and microbial derived signatures that affect innate immune cell function and vascular health.

 

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Research Output

Loss of Diurnal Oscillatory Rhythms in Gut Microbiota Correlates with Changes in Circulating Metabolites in Type 2 Diabetic db/db Mice

Beli, E., Prabakaran, S., Krishnan, P., Evans-Molina, C. & Grant, M. B., 29 Sep 2019, In : Nutrients. 11, 10, 19 p., 2310.

Research output: Contribution to journalArticle

Open Access
File
  • 7 Citations (Scopus)
    89 Downloads (Pure)

    Loss of Angiotensin-Converting Enzyme 2 Exacerbates Diabetic Retinopathy by Promoting Bone Marrow Dysfunction

    Duan, Y., Beli, E., Li Calzi, S., Quigley, J. L., Miller, R. C., Moldovan, L., Feng, D., Salazar, T. E., Hazra, S., Al-Sabah, J., Chalam, K. V., Phuong Trinh, T. L., Meroueh, M., Markel, T. A., Murray, M. C., Vyas, R. J., Boulton, M. E., Parsons-Wingerter, P., Oudit, G. Y., Obukhov, A. G. & 1 others, Grant, M. B., 15 Jul 2018, In : Stem Cells. 36, 9, p. 1430-1440 11 p.

    Research output: Contribution to journalArticle

  • 10 Citations (Scopus)

    Restructuring of the Gut Microbiome by Intermittent Fasting Prevents Retinopathy and Prolongs Survival in db/db Mice

    Beli, E., Yan, Y., Moldovan, L., Vieira, C. P., Gao, R., Duan, Y., Prasad, R., Bhatwadekar, A., White, F. A., Townsend, S. D., Chan, L., Ryan, C. N., Morton, D., Moldovan, E. G., Chu, F-I., Oudit, G. Y., Derendorf, H., Adorini, L., Wang, X. X., Evans-Molina, C. & 7 others, Mirmira, R. G., Boulton, M. E., Yoder, M. C., Li, Q., Levi, M., Busik, J. V. & Grant, M. B., 22 Aug 2018, In : Diabetes. 67, 9, p. 1867-1879 13 p.

    Research output: Contribution to journalArticle

  • 34 Citations (Scopus)

    Bone Marrow-Derived Cell Recruitment to the Neurosensory Retina and Retinal Pigment Epithelial Cell Layer Following Subthreshold Retinal Phototherapy

    Caballero, S., Kent, D. L., Sengupta, N., Li Calzi, S., Shaw, L., Beli, E., Moldovan, L., Dominguez, J. M., Moorthy, R. S. & Grant, M. B., 01 Oct 2017, In : Investigative ophthalmology & visual science. 58, 12, p. 5164-5176 13 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 8 Citations (Scopus)
    1 Downloads (Pure)

    The Mechanism of Diabetic Retinopathy Pathogenesis Unifying Key Lipid Regulators, Sirtuin 1 and Liver X Receptor

    Hammer, S. S., Beli, E., Kady, N., Wang, Q., Wood, K., Lydic, T. A., Malek, G., Saban, D. R., Wang, X. X., Hazra, S., Levi, M., Busik, J. V. & Grant, M. B., 11 Jul 2017, In : EBioMedicine. 22, p. 181-190 10 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 17 Citations (Scopus)
    2 Downloads (Pure)

    Prizes

    Vice Chancellor Fellowship

    Beli, Eleni (Recipient), 15 Jan 2019

    Prize: Fellowship awarded competitively

    JDRF Advanced Postdoctoral Fellowship

    Beli, Eleni (Recipient), 01 Mar 2017

    Prize: Fellowship awarded competitively

    Bouyoukos Fellowship

    Beli, Eleni (Recipient), 01 May 2004

    Prize: Fellowship awarded competitively

    American Diabetes Association Young Investigator Award

    Beli, Eleni (Recipient), 2017

    Prize: Prize (including medals and awards)

    Chronobiology Training School SRBR Travel Award

    Beli, Eleni (Recipient), 2019

    Prize: Prize (including medals and awards)

    Activities

    • 9 Publication peer-review
    • 3 Oral presentation
    • 2 Invited talk
    • 1 Hosting an academic visitor

    "Circadian Clocks in Diabetes- Implications for Diabetic Retinopathy"

    Eleni Beli (Speaker)

    11 Sep 2020

    Activity: Talk or presentation typesOral presentation

    2nd International Conference on EYE Diseases

    Eleni Beli (Speaker)

    15 Jul 202017 Jul 2020

    Activity: Talk or presentation typesOral presentation

    "What is the influence of a disrupted circadian clock in the progression of diabetic retinopathy?"

    Eleni Beli (Speaker)

    07 Feb 2020

    Activity: Talk or presentation typesInvited talk

    Frontiers in immunology (Journal)

    Eleni Beli (Peer reviewer)

    2020 → …

    Activity: Publication peer-review and editorial work typesPublication peer-review

    "Diurnal rhythms of myeloid cell infiltration into the retina in type 1 diabetes (T1D)"

    Eleni Beli (Speaker)

    05 Nov 202007 Nov 2020

    Activity: Talk or presentation typesOral presentation