Research Output per year
Personal profile
Research Focus
Living with diabetes has been made easier with insulin pumps and medications. However, the risk of developing complications remains high, and a diagnosis of diabetic retinopathy, the most common diabetic complication can be scary and confusing. Our laboratory is interested in the role of circadian rhythms in the progression of diabetic retinopathy, in chronotiming drug delivery and biomarker sampling and in designing non invasive lifestyle interventions to delay the onset of diabetic retinopathy.
We are focused in studying physiological and systemic parameters affecting innate immunity and retinal health. We use type 1 and type 2 diabetic models and multi-omics approaches to identify metablic and microbial derived signatures that affect innate immune cell function and vascular health.
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Network
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Research Output
Loss of Diurnal Oscillatory Rhythms in Gut Microbiota Correlates with Changes in Circulating Metabolites in Type 2 Diabetic db/db Mice
Beli, E., Prabakaran, S., Krishnan, P., Evans-Molina, C. & Grant, M. B., 29 Sep 2019, In : Nutrients. 11, 10, 19 p., 2310.Research output: Contribution to journal › Article
Open Access
File
Loss of Angiotensin-Converting Enzyme 2 Exacerbates Diabetic Retinopathy by Promoting Bone Marrow Dysfunction
Duan, Y., Beli, E., Li Calzi, S., Quigley, J. L., Miller, R. C., Moldovan, L., Feng, D., Salazar, T. E., Hazra, S., Al-Sabah, J., Chalam, K. V., Phuong Trinh, T. L., Meroueh, M., Markel, T. A., Murray, M. C., Vyas, R. J., Boulton, M. E., Parsons-Wingerter, P., Oudit, G. Y., Obukhov, A. G. & 1 others, , 15 Jul 2018, In : Stem Cells. 36, 9, p. 1430-1440 11 p.Research output: Contribution to journal › Article
3
Citations
(Scopus)
Restructuring of the Gut Microbiome by Intermittent Fasting Prevents Retinopathy and Prolongs Survival in db/db Mice
Beli, E., Yan, Y., Moldovan, L., Vieira, C. P., Gao, R., Duan, Y., Prasad, R., Bhatwadekar, A., White, F. A., Townsend, S. D., Chan, L., Ryan, C. N., Morton, D., Moldovan, E. G., Chu, F-I., Oudit, G. Y., Derendorf, H., Adorini, L., Wang, X. X., Evans-Molina, C. & 7 others, , 22 Aug 2018, In : Diabetes. 67, 9, p. 1867-1879 13 p.Research output: Contribution to journal › Article
21
Citations
(Scopus)
Bone Marrow-Derived Cell Recruitment to the Neurosensory Retina and Retinal Pigment Epithelial Cell Layer Following Subthreshold Retinal Phototherapy
Caballero, S., Kent, D. L., Sengupta, N., Li Calzi, S., Shaw, L., Beli, E., Moldovan, L., Dominguez, J. M., Moorthy, R. S. & Grant, M. B., 01 Oct 2017, In : Investigative ophthalmology & visual science. 58, 12, p. 5164-5176 13 p.Research output: Contribution to journal › Article
Open Access
File
6
Citations
(Scopus)
The Mechanism of Diabetic Retinopathy Pathogenesis Unifying Key Lipid Regulators, Sirtuin 1 and Liver X Receptor
Hammer, S. S., Beli, E., Kady, N., Wang, Q., Wood, K., Lydic, T. A., Malek, G., Saban, D. R., Wang, X. X., Hazra, S., Levi, M., Busik, J. V. & Grant, M. B., 11 Jul 2017, In : EBioMedicine. 22, p. 181-190 10 p.Research output: Contribution to journal › Article
Open Access
File
15
Citations
(Scopus)
2
Downloads
(Pure)
Prizes
Vice Chancellor Fellowship
Eleni Beli (Recipient), 15 Jan 2019
Prize: Fellowship awarded competitively
JDRF Advanced Postdoctoral Fellowship
Eleni Beli (Recipient), 01 Mar 2017
Prize: Fellowship awarded competitively