Photo of Emma Kerr
  • Room 03.007 - CCRCB

    United Kingdom

Accepting PhD Students

20122019

Research output per year

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Research Output

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Article
2018

Exploring the role of stromal osmoregulation in cancer and disease using executable modelling

Shorthouse, D., Reidel, A., Kerr, E., Pedro, L., Bihary, D., Samarajiwa, S., Martins, C., Shields, J. & Hall, B., 01 Aug 2018, In : Nature Communications. 9, 15 p., 3011.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
22 Downloads (Pure)

The ERBB network facilitates KRAS-driven lung tumorigenesis

Kruspig, B., Monteverde, T., Neidler, S., Hock, A., Kerr, E., Nixon, C., Clark, W., Hedley, A., Laing, S., Coffelt, S. B., Le Quesne, J., Dick, C., Vousden, K., Martins, C. P. & Murphy, D. J., 20 Jun 2018, In : Science Translational Medicine. 10, 446

Research output: Contribution to journalArticle

21 Citations (Scopus)
2017

KRAS Allelic Imbalance Strengths and Weaknesses in Numbers

Doherty, G. J., Kerr, E. M. & Martins, C. P., 31 Mar 2017, In : Trends in molecular medicine. 23, 5, p. 377-378

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
178 Downloads (Pure)

Lung tumors with distinct p53 mutations respond similarly to p53 targeted therapy but exhibit genotype-specific statin sensitivity

Turrell, F. K., Kerr, E. M., Gao, M., Thorpe, H., Doherty, G. J., Cridge, J., Shorthouse, D., Speed, A., Samarajiwa, S., Hall, B. A., Griffiths, M. & Martins, C. P., 08 Aug 2017, In : Genes & development. 31, 13, p. 1339-1353 15 p.

Research output: Contribution to journalArticle

Open Access
File
30 Citations (Scopus)
140 Downloads (Pure)
2016

Mutant Kras copy number defines metabolic reprogramming and therapeutic susceptibilities

Kerr, E. M., Gaude, E., Turrell, F. K., Frezza, C. & Martins, C. P., 03 Mar 2016, In : Nature. 531, 7592, p. 110-3 4 p.

Research output: Contribution to journalArticle

128 Citations (Scopus)
2014

Differential affinity of FLIP and procaspase 8 for FADD's DED binding surfaces regulates DISC assembly

Majkut, J., Sgobba, M., Holohan, C., Crawford, N., Logan, A. E., Kerr, E., Higgins, C. A., Redmond, K. L., Riley, J. S., Stasik, I., Fennell, D. A., Van Schaeybroeck, S., Haider, S., Johnston, P. G., Haigh, D. & Longley, D. B., 28 Feb 2014, In : Nature Communications. 5, 3350.

Research output: Contribution to journalArticle

40 Citations (Scopus)
2012

Identification of an acetylation-dependant Ku70/FLIP complex that regulates FLIP expression and HDAC inhibitor-induced apoptosis

Kerr, E., Holohan, C., McLaughlin, KM., Majkut, J., Dolan, S., Redmond, K., Riley, J., McLaughlin, K., Stasik, I., Crudden, M., Van Schaeybroeck, S., Fenning, C., O'Connor, R., Kiely, P., Sgobba, M., Haigh, D., Johnston, PG. & Longley, DB., Aug 2012, In : Cell Death and Differentiation. 19, 8, p. 1317-1327 11 p., e1745.

Research output: Contribution to journalArticle

59 Citations (Scopus)

Vorinostat/SAHA-induced apoptosis in malignant mesothelioma is FLIP/caspase 8-dependent and HR23B-independent.

Hurwitz, J., Stasik, I., Kerr, E., Holohan, C., Johnston, P., Fennell, D. & Longley, D., May 2012, In : European Journal of Cancer. 48, 7, p. 1096-107 12 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)