Projects per year
Personal profile
Particulars
Eneko Larrañeta is a Professor at Queen's University Belfast, specialising in drug delivery systems and biomaterials. He holds a BSc in Chemistry and a PhD in Physical Chemistry from the University of Navarra, where his research focused on self-assembled hydrogels. After completing his PhD in 2012, Prof. Larrañeta worked as a research fellow in nanotechnology for drug delivery before moving to Belfast in 2013 to develop microneedle technology for transdermal drug delivery at Queen's University.
Prof. Larrañeta's expertise includes hydrogels, nano/microparticles, and microneedle-based systems. Currently, he focuses on implantable systems for sustained drug release, using techniques such as melt processing and additive manufacturing. He has published over 100 papers in peer-reviewed journals, edited multiple books, and authored numerous book chapters. Prof. Larrañeta has secured funding from leading organisations and collaborated extensively with pharmaceutical and cosmetics companies.
In 2023, he was named a Clarivate Highly Cited Researcher, and since 2019, he has been recognised as a top 2% scientist in his field by Stanford University's analysis using Scopus data. He is a Fellow of the UK Higher Education Academy and a member of the Royal Society of Chemistry and the Society for Applied Microbiology.
Research Interests
Prof. Larrañeta research interests are centred on design and physicochemical characterisation of advanced implantabe drug delivery systems. These devices can be used for a wide variety of applications such as to replace a fraction of a biological structure or to provide a specific therapy.
It is estimated that between 5 and 6% of people in industrialized countries have experienced the implantation of a medical device for rebuilding some body functions. These devices can be manufactured containing drugs in their structures with diverse funcions such as prevent infection/inflamation or to provide a prolonged drug release. The latter application is particularly interesting, as long-acting and implantable drug delivery systems offer the possibility of providing localised and unattended therapy for a wide variety of conditions. These systems present multiple advantages over the conventional systems used for drug delivery and allow to reduce drug dosage while improving patient compliance. These features are particularly important for the treatment of chronic conditions. According to the World Health Organization, chronic conditions are the major cause of disabilities worldwide, and the burden of chronic diseases is increasing rapidly.
Prof. Larrañeta is currently working on the development of diverse types of drug eluting implantable devices. These devices are commonly made of polymeric materials. The properties of these materials can be tailored by altering the composition of these devices. In this way, drug release profiles can be tailored to the specific applications adapting to patient's needs. Finally, stateof-the-art techniques such as 3D printing can be applied for the development of implantable devices.
Teaching
PMY2203: Medicinal Substances
Prof. Larrañeta delivers the content related with Applied Pharmaceutical Analysis, Mass Spectrometry and Nuclear Magnetic resonance analysis during the first semester. Additionally, he covers Enzyme Kinetics, Pro-drugs and Beta-blockers during second semestre.
PMY2304: Pharmaceutical Analysis
Prof. Larrañeta delivers the content related with Applied Pharmaceutical Analysis, Mass Spectrometry and Nuclear Magnetic resonance analysis during the first semester.
PMY1024: Properties and analysis of drug molecules
Prof. Larrañeta delivers the content related with UV-visible, fluorescence, IR and Raman spectroscopies
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Collaborations and top research areas from the last five years
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R6617PMY: Ocular Research By Integrated Training And Learning
Singh, T. R. R. (PI), Donnelly, R. (CoI) & Larrañeta, E. (CoI)
03/05/2019 → …
Project: Research
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R1040PMY: Nanoengineered microneedle arrays for enhanced delivery of long-acting HIV medicines
Donnelly, R. (PI) & Larrañeta, E. (CoI)
27/03/2019 → 30/09/2023
Project: Research
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R2493PMY: 3D printable antimicrobial materials for the development of safer medical devices
Larrañeta, E. (PI) & Irwin, N. (CoI)
11/06/2018 → 10/08/2018
Project: Research
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R2481PMY: Development of antimicrobial materials made of natural compounds prepared using 3D printing
Larrañeta, E. (PI) & Irwin, N. (CoI)
23/04/2018 → 27/07/2018
Project: Research
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R2473PMY: Sustainable materials for prevention of catheter complications
Irwin, N. (PI) & Larrañeta, E. (CoI)
13/04/2018 → 17/08/2018
Project: Research
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3D-printed long-acting implants for risperidone delivery using VAT photopolymerisation: a potential alternative for schizophrenia treatment
Picco, C. J., Utomo, E., Magill, E. R., Anjani, Q. K., Adhami, M., Lu, Y., Byrne, N. M., Ammar, A. A., Coulter, J. A., Donnelly, R. F., Domínguez-Robles, J. & Larrañeta, E., 10 Aug 2026, In: International Journal of Pharmaceutics. 701, 12 p., 127092.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Downloads (Pure) -
Assessment of leachables and extractables in “super-swelling” hydrogel-forming microarray patches
Anjani, Q. K., McKenna, P. E., Larrañeta, E., Manesiotis, P., Luo, Y., Adhami, M., Volpe-Zanutto, F., Orr, G., Roussel, S. & Donnelly, R. F., Jan 2026, In: Drug Delivery and Translational Research. 16, 1, p. 397-409 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Link opens in a new tab Citations (Scopus)125 Downloads (Pure) -
Assessment of microneedle array insertion into skin using Raman spectroscopic techniques
Jamaledin, R., Zarmpi, P., Alambiaga-Caravaca, A. M., Tyagi, V., Anjani, Q. K., Larrañeta, E., Donnelly, R. F., Belsey, N. A., Guy, R. H. & Delgado-Charro, M. B., 13 Jan 2026, (Early online date) In: Drug Delivery and Translational Research. 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Downloads (Pure) -
Design and formulation strategies to modulate drug release from implantable devices
Magill, E. R., Adhami, M., Fandiño, O. E., Lu, Y., Domínguez-Robles, J. & Larrañeta, E., 05 Jun 2026, In: International Journal of Pharmaceutics. 698, 34 p., 126947.Research output: Contribution to journal › Review article › peer-review
Open AccessFile8 Downloads (Pure) -
Expanded perlite and barium sulfate as enablers for biomedical applications of 3D-printed PLA biocomposites: Thermo-mechanical properties, bacterial adhesion inhibition, and antimicrobial activity
Herbst, G., Adhami, M., Sebbar, K., Larrañeta, E., Corazza, M. L., Ramos, L. P. & Delgado-Aguilar, M., May 2026, In: Journal of Materials Research and Technology. 42, p. 5801-5812 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Downloads (Pure)
Prizes
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Academy of Medical Sciences Springboard Award
Larrañeta, E. (Recipient), 31 Jan 2020
Prize: Fellowship awarded competitively
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Best Paper Award of Pharmaceutics Special Issue on 3D Printing of Pharmaceuticals and Drug Delivery Devices
Dominguez Robles, J. (Recipient), Martin, N. K. (Recipient), Fong, M. L. (Recipient), Stewart, S. (Recipient), Irwin, N. (Recipient), Rial, I. (Recipient), Donnelly, R. (Recipient) & Larrañeta, E. (Recipient), 2020
Prize: Other distinction
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Fellow of the Higher Education Academy
Larrañeta, E. (Recipient), 2018
Prize: Election to learned society
Activities
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Design and Fabrication of Drug-Eluting Implants Using 3D Printing
Larrañeta, E. (Advisor)
25 Jun 2026Activity: Talk or presentation types › Invited talk
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Development of dissolving and hydrogel-forming microneedles for transdermal delivery of non-ergoline dopamine agonists
Larrañeta, E. (Examiner)
05 Jun 2026Activity: Examination types › Other examination
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Hydrophobic ion pairing as a rational surface engineering strategy for enhanced protein integration within lipid-based nanocarriers
Larrañeta, E. (Examiner)
11 May 2026Activity: Examination types › Other examination
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Formulation and Characterisation of In Situ Forming Ocular Depot Implants for Sustained Protein Delivery
Larrañeta, E. (Examiner)
08 May 2026Activity: Examination types › Other examination
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Design and formulation strategies in the development of implants for drug delivery
Larrañeta, E. (Invited speaker)
26 Mar 2026Activity: Talk or presentation types › Invited talk
Press/Media
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Queen’s University Belfast provides NHS with protective facemasks
Lamprou, D., Larrañeta, E., Dominguez Robles, J. & Falzon, B.
26/03/2020 → 23/04/2020
20 items of Media coverage
Press/Media: Research