Projects per year
Personal profile
Particulars
Eneko Larrañeta is a Professor at Queen's University Belfast, specialising in drug delivery systems and biomaterials. He holds a BSc in Chemistry and a PhD in Physical Chemistry from the University of Navarra, where his research focused on self-assembled hydrogels. After completing his PhD in 2012, Prof. Larrañeta worked as a research fellow in nanotechnology for drug delivery before moving to Belfast in 2013 to develop microneedle technology for transdermal drug delivery at Queen's University.
Prof. Larrañeta's expertise includes hydrogels, nano/microparticles, and microneedle-based systems. Currently, he focuses on implantable systems for sustained drug release, using techniques such as melt processing and additive manufacturing. He has published over 100 papers in peer-reviewed journals, edited multiple books, and authored numerous book chapters. Prof. Larrañeta has secured funding from leading organisations and collaborated extensively with pharmaceutical and cosmetics companies.
In 2023, he was named a Clarivate Highly Cited Researcher, and since 2019, he has been recognised as a top 2% scientist in his field by Stanford University's analysis using Scopus data. He is a Fellow of the UK Higher Education Academy and a member of the Royal Society of Chemistry and the Society for Applied Microbiology.
Research Interests
Prof. Larrañeta research interests are centred on design and physicochemical characterisation of advanced implantabe drug delivery systems. These devices can be used for a wide variety of applications such as to replace a fraction of a biological structure or to provide a specific therapy.
It is estimated that between 5 and 6% of people in industrialized countries have experienced the implantation of a medical device for rebuilding some body functions. These devices can be manufactured containing drugs in their structures with diverse funcions such as prevent infection/inflamation or to provide a prolonged drug release. The latter application is particularly interesting, as long-acting and implantable drug delivery systems offer the possibility of providing localised and unattended therapy for a wide variety of conditions. These systems present multiple advantages over the conventional systems used for drug delivery and allow to reduce drug dosage while improving patient compliance. These features are particularly important for the treatment of chronic conditions. According to the World Health Organization, chronic conditions are the major cause of disabilities worldwide, and the burden of chronic diseases is increasing rapidly.
Prof. Larrañeta is currently working on the development of diverse types of drug eluting implantable devices. These devices are commonly made of polymeric materials. The properties of these materials can be tailored by altering the composition of these devices. In this way, drug release profiles can be tailored to the specific applications adapting to patient's needs. Finally, stateof-the-art techniques such as 3D printing can be applied for the development of implantable devices.
Teaching
PMY2203: Medicinal Substances
Prof. Larrañeta delivers the content related with Applied Pharmaceutical Analysis, Mass Spectrometry and Nuclear Magnetic resonance analysis during the first semester. Additionally, he covers Enzyme Kinetics, Pro-drugs and Beta-blockers during second semestre.
PMY2304: Pharmaceutical Analysis
Prof. Larrañeta delivers the content related with Applied Pharmaceutical Analysis, Mass Spectrometry and Nuclear Magnetic resonance analysis during the first semester.
PMY1024: Properties and analysis of drug molecules
Prof. Larrañeta delivers the content related with UV-visible, fluorescence, IR and Raman spectroscopies
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Collaborations and top research areas from the last five years
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R6617PMY: Ocular Research By Integrated Training And Learning
Singh, T. R. R. (PI), Donnelly, R. (CoI) & Larrañeta, E. (CoI)
03/05/2019 → …
Project: Research
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R1040PMY: Nanoengineered microneedle arrays for enhanced delivery of long-acting HIV medicines
Donnelly, R. (PI) & Larrañeta, E. (CoI)
27/03/2019 → 30/09/2023
Project: Research
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R2493PMY: 3D printable antimicrobial materials for the development of safer medical devices
Larrañeta, E. (PI) & Irwin, N. (CoI)
11/06/2018 → 10/08/2018
Project: Research
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R2481PMY: Development of antimicrobial materials made of natural compounds prepared using 3D printing
Larrañeta, E. (PI) & Irwin, N. (CoI)
23/04/2018 → 27/07/2018
Project: Research
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R2473PMY: Sustainable materials for prevention of catheter complications
Irwin, N. (PI) & Larrañeta, E. (CoI)
13/04/2018 → 17/08/2018
Project: Research
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3D-printed acyclovir nanocrystals: an advanced approach to herpes simplex treatment
Lopez-Vidal, L., Juskaite, K., Fandino, O., Fuster, M. G., Sangalli, M., Adhami, M., Wang, J., Palma, S. D., Volpe-Zanutto, F., Larrañeta, E. & Paredes, A. J., Jun 2025, In: Applied Materials Today. 44, 14 p., 102695.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)35 Downloads (Pure) -
3D printed hydrogels: a promising material for biomedical applications
Bickerstaff, E., Mehdi-Sefiani, H., Chicardi, E., Sepúlveda, R., Pérez-Puyana, V. M., Adhami, M., Larrañeta, E. & Domínguez-Robles, J., 28 Feb 2025, Hydrogels in drug delivery. Paredes, A. J., Larrañeta, E., Laverty, G. & Donnelly, R. F. (eds.). Elsevier Inc., p. 379-412 34 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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3D-printing of dipyridamole/thermoplastic polyurethane materials for bone regeneration
Adhami, M., Dastidar, A. G., Anjani, Q. K., Detamornrat, U., Tarrés, Q., Delgado-Aguilar, M., Acheson, J. G., Manda, K., Clarke, S. A., Moreno-Castellanos, N., Larrañeta, E. & Domínguez-Robles, J., 01 Jul 2025, In: Drug Delivery and Translational Research. 15, 7, p. 2467-2482 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)39 Downloads (Pure) -
Assessment of leachables and extractables in “super-swelling” hydrogel-forming microarray patches
Anjani, Q. K., McKenna, P. E., Larrañeta, E., Manesiotis, P., Luo, Y., Adhami, M., Volpe-Zanutto, F., Orr, G., Roussel, S. & Donnelly, R. F., 31 May 2025, (Early online date) In: Drug Delivery and Translational Research. 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)35 Downloads (Pure) -
Author correction: Microneedle-based biosensing
Vora, L. K., Sabri, A. H., McKenna, P. E., Himawan, A., Hutton, A. R. J., Detamornrat, U., Paredes, A. J., Larrañeta, E. & Donnelly, R. F., Sept 2025, In: Nature Reviews Bioengineering. 3, 804.Research output: Contribution to journal › Comment/debate › peer-review
Prizes
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Academy of Medical Sciences Springboard Award
Larrañeta, E. (Recipient), 31 Jan 2020
Prize: Fellowship awarded competitively
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Best Paper Award of Pharmaceutics Special Issue on 3D Printing of Pharmaceuticals and Drug Delivery Devices
Dominguez Robles, J. (Recipient), Martin, N. K. (Recipient), Fong, M. L. (Recipient), Stewart, S. (Recipient), Irwin, N. (Recipient), Rial, I. (Recipient), Donnelly, R. (Recipient) & Larrañeta, E. (Recipient), 2020
Prize: Other distinction
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Fellow of the Higher Education Academy
Larrañeta, E. (Recipient), 2018
Prize: Election to learned society
Activities
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Beyond Bioprinting: Bioscaffolder as a Versatile Platform for Drug Delivery Applications
Larrañeta, E. (Invited speaker)
04 Nov 2025Activity: Talk or presentation types › Invited or keynote talk at national or international conference
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3D-printed implantable devices for controlled drug release.
Larrañeta, E. (Invited speaker)
28 Oct 2025Activity: Talk or presentation types › Invited talk
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Design of next-generation implants for sustained drug delivery.
Larrañeta, E. (Invited speaker)
30 Sept 2025Activity: Talk or presentation types › Invited talk
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Preclinical Evaluation of Dissolvable Microarray Patches for Allergy Treatment: Key Factors Governing In Vitro and In Silico Assessment
Larrañeta, E. (Examiner)
22 Sept 2025Activity: Examination types › PhD external examination
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Innovative Implantable Systems for Targeted and Sustained Drug Delivery
Larrañeta, E. (Invited speaker)
21 Aug 2025Activity: Talk or presentation types › Invited talk
Press/Media
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Queen’s University Belfast provides NHS with protective facemasks
Lamprou, D., Larrañeta, E., Dominguez Robles, J. & Falzon, B.
26/03/2020 → 23/04/2020
20 items of Media coverage
Press/Media: Research