Projects per year
Personal profile
Research Statement
My research theme focuses on pain and inflammation in the oral cavity and respiratory tract. I have developed non-animal models, including neuronal models differentiated from adult human dental pulp stem cells and induced pluripotent stem cells (iPSCs) to gain a better insight into neuronal responses that reflect human physiology. My work on pain and neurogenic inflammation, and the neuro-inflammatory response to infection, has naturally extended into the related field of transient receptor potential (TRP) channel research and the modulation of these important channels during the inflammatory and regenerative processes. I am particularly interested in the interplay between the innate immune response to infection, and the reparative and regenerative potential of adult stem cells. I also have an interest in studying the stability of host defence peptides and proteins in the inflammatory milieu, and in the design of peptide mimetics with resistance to proteinases and enhanced efficacy against bacterial and fungal pathogens in biofilm form. I have published >70 peer reviewed articles in learned journals and have been successful in obtaining competitive research grant income from a range of funding agencies such as EU INTERREG, NC3Rs, MRC, Pain Relief Foundation, Animal Free Research, HSC R&D Office and the British Society for Antimicrobial Chemotherapy. I currently chair the successful regenerative medicine (REMERGE) group, a multidisciplinary team of academic and clinical researchers, with a focus on using regenerative medicine techniques to study and treat a range of clinical conditions.
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Network
Projects
- 1 Finished
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R1558CII: MRC P2D 2015 - Adult mesenchymal stem cell culture and differentiation in commercial hydrogels
04/09/2015 → 30/11/2016
Project: Research
Research Output
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A connectivity mapping approach predicted acetylsalicylic acid (aspirin) to induce osteo/odontogenic differentiation of dental pulp cells
Rankin, R., Lundy, F., Schock, B. C., Zhang, S. D., Al-Natour, B., About, I., Irwin, C., Linden, G. J. & El Karim, I. A., Jun 2020, In : International Endodontic Journal. 53, 6, p. 834-845 12 p.Research output: Contribution to journal › Article › peer-review
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Natural Antimicrobials in the Dental Pulp
Lundy, F. T., Irwin, C. R., McLean, D. F., Linden, G. J. & El Karim, I. A., 01 Sep 2020, In : Journal of Endodontics. 46, supplement of issue 9, p. S2-S9Research output: Contribution to journal › Article › peer-review
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Perspectives on neuroinflammation contributing to chronic cough
Driessen, A., Devlin, A-C., Lundy, F., Martin, L., Sergeant, G. P., Mazzone, S. B. & McGarvey, L., 09 Jul 2020, In : European Respiratory Journal.Research output: Contribution to journal › Literature review › peer-review
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A Comparative Analysis of the Osteogenic Potential of Dental Mesenchymal Stem Cells
Winning, L., El Karim, I. A. & Lundy, F. T., 01 Aug 2019, In : Stem Cells and Development. 28, 15, p. 1050-1058 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)76 Downloads (Pure) -
Current and Future Views on Pulpal Pain and Neurogenesis
Lundy, F., El Karim, I. & Scheven, B., 2019, Clinical Approaches in Endodontic Regeneration, Current and Emerging Therapeutic Perspectives. Springer Nature Switzerland, p. 19-36Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review
Prizes
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Asthma/COPD Project of the Year, 19th Northern Ireland Healthcare Awards
Martin, Lorraine (Recipient), McGarvey, Lorcan (Recipient), Lundy, Fionnuala (Recipient), Keith Thornbury (Recipient), Mark Hollywood (Recipient), Gerard Sergeant (Recipient), John Lockhart (Recipient), Gary Litherland (Recipient) & Anne Crilly (Recipient), 22 Feb 2018
Prize: Prize (including medals and awards)
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International Association for Dental Research (IADR)/ GlakoSmithKline (GSK) Innovation in Oral Care Award. The IADR's most prestigious monetary prize (CI, Dr F Lundy)
Lundy, Fionnuala (Recipient), 2011
Prize: Prize (including medals and awards)
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International Association for Dental Research (IADR)/ GlakoSmithKline (GSK) Innovation in Oral Care Award. The IADR's most prestigious monetary prize (PI, Dr F Lundy)
Lundy, Fionnuala (Recipient), 2007
Prize: Prize (including medals and awards)
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PhD student Denise McLean (Principal Supervisor Dr F Lundy) won the Best Poster Prize at the 18th International Symposium on Regulatory Peptides
Lundy, Fionnuala (Recipient), 2010
Prize: Prize (including medals and awards)
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PhD Student Jamie Toole (Principal Supervisor Dr F Lundy) won the Royal College of Surgeons in Ireland (RCSI) Clinical Prize
Lundy, Fionnuala (Recipient), 2014
Prize: Prize (including medals and awards)
Activities
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Efficacy and Mechanism Evaluation (EME) Programme (External organisation)
Fionnuala Lundy (Reviewer)
2019 → 2022Activity: Membership types › Membership of peer review panel or committee
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Hosting Lurgan College, Work Experience Student
Fionnuala Lundy (Host)
16 Jan 2019 → 18 Jan 2019Activity: Other activity types › Hosting a school group or open day
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6th IADR Academy: Dental Stem Cells – Resolving Contradictions and Looking Forward
Fionnuala Lundy (Participant)
24 Jul 2018Activity: Participating in or organising an event types › Participation in workshop, seminar, course
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Invited Lecture at the Launch of the Centre for Global Infectious Diseases, Durham University: Peptoids - antibiofilm activity and efficacy in an in vivo infection model
Fionnuala Lundy (Invited speaker)
15 Jun 2018Activity: Talk or presentation types › Invited talk
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Launch of MATRIX NI (NI Science Industry Panel) 'Women in STEM' at Titanic Exhibition Centre Belfast
Fionnuala Lundy (Member)
23 May 2018Activity: Other activity types › Other
Press / Media
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MATRIX NI Successful Women in Science
23/05/2018
1 Media contribution
Press/Media: Public Engagement Activities