Projects per year
Personal profile
Research Statement
My research theme focuses on pain and inflammation in the oral cavity and respiratory tract. I have developed non-animal models, including neuronal models differentiated from adult human dental pulp stem cells and induced pluripotent stem cells (iPSCs) to gain a better insight into neuronal responses that reflect human physiology. My work on pain and neurogenic inflammation, and the neuro-inflammatory response to infection, has naturally extended into the related field of transient receptor potential (TRP) channel research and the modulation of these important channels during the inflammatory and regenerative processes. I am particularly interested in the interplay between the innate immune response to infection, and the reparative and regenerative potential of adult stem cells. I also have an interest in studying the stability of host defence peptides and proteins in the inflammatory milieu, and in the design of peptide mimetics with resistance to proteinases and enhanced efficacy against bacterial and fungal pathogens in biofilm form. I have published >70 peer reviewed articles in learned journals and have been successful in obtaining competitive research grant income from a range of funding agencies such as EU INTERREG, NC3Rs, MRC, Pain Relief Foundation, Animal Free Research, HSC R&D Office and the British Society for Antimicrobial Chemotherapy. I currently chair the successful regenerative medicine (REMERGE) group, a multidisciplinary team of academic and clinical researchers, with a focus on using regenerative medicine techniques to study and treat a range of clinical conditions.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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R4826CEM: Endodontic infections and CardiOvascular disease risk (ECO): A prospective study of a possible link?
El Karim, I., Linden, G. & Lundy, F.
08/06/2018 → …
Project: Research
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R6964PMY: Interreg VA: BREATH - Border and REgions Airways Training Hub (Full Proposal)
Martin, L., Lundy, F., McGarvey, L. & Tikhonova, I.
02/05/2017 → …
Project: Research
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R2258CII: Mas related gene receptors as novel modules for pain relief
El Karim, I., Curtis, T. & Lundy, F.
16/12/2015 → …
Project: Research
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Ficus septica exudate, a traditional medicine used in Papua New Guinea for treating infected cutaneous ulcers: in vitro evaluation and clinical efficacy assessment by cluster randomised trial
Deli, J., González-Beiras, C., Guldan, G. S., Moses, R. L., Dally, J., Moseley, R., Lundy, F. T., Corbacho-Monne, M., Walker, S. L., Cazorla, M. U., Ouchi, D., Fang, R., Briggs, M., Kiapranis, R., Yahimbu, M., Mitjà, O. & Prescott, T. A. K., May 2022, In: Phytomedicine. 99, 154026.Research output: Contribution to journal › Article › peer-review
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Novel Antibacterial Properties of the Human Dental Pulp Multipotent Mesenchymal Stromal Cell Secretome
Ravenscroft, H., El Karim, I., Krasnodembskaya, A. D., Gilmore, B., About, I. & Lundy, F. T., 23 Mar 2022, (Early online date) In: The American journal of pathology.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Apical Periodontitis and All-Cause Mortality Among 60-70 Year-Old Men
McClory, M., Lundy, F., Winning, L., Linden, G. & El Karim, I., 05 Feb 2021, In: Journal of Dental Research. 100, Spec IssBResearch output: Contribution to journal › Meeting abstract › peer-review
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A protocol for the Development of CoreOutcome Sets for Endodontic Treatmentmodalities (COSET): an internationalconsensus process
El Karim, I. A., Duncan, H. F., Cushley, S., Nagendrababu, V., Kirkevang, L. L., Kruse, C., Chong, B. S., Shah, P. K., Lappin, M., McLister, C., Lundy, F. T. & Clarke, M., 17 Nov 2021, In: Trials. 22, 1, p. 812Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Downloads (Pure) -
Deciphering Reparative Processes in the Inflamed Dental Pulp
El karim, I. A., Cooper, P. R., About, I., Tomson, P. L., Lundy, F. T. & Duncan, H. F., 31 Mar 2021, In: Frontiers in Dental Medicine. 2, 10 p., 651219.Research output: Contribution to journal › Review article › peer-review
Open AccessFile107 Downloads (Pure)
Prizes
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Asthma/COPD Project of the Year, 19th Northern Ireland Healthcare Awards
Martin, Lorraine (Recipient), McGarvey, Lorcan (Recipient), Lundy, Fionnuala (Recipient), Thornbury, K. (Recipient), Hollywood, M. (Recipient), Sergeant, G. (Recipient), Lockhart, J. (Recipient), Litherland, G. (Recipient) & Crilly, A. (Recipient), 22 Feb 2018
Prize: Prize (including medals and awards)
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International Association for Dental Research (IADR)/ GlakoSmithKline (GSK) Innovation in Oral Care Award. The IADR's most prestigious monetary prize (CI, Dr F Lundy)
Lundy, Fionnuala (Recipient), 2011
Prize: Prize (including medals and awards)
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International Association for Dental Research (IADR)/ GlakoSmithKline (GSK) Innovation in Oral Care Award. The IADR's most prestigious monetary prize (PI, Dr F Lundy)
Lundy, Fionnuala (Recipient), 2007
Prize: Prize (including medals and awards)
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PhD student Denise McLean (Principal Supervisor Dr F Lundy) won the Best Poster Prize at the 18th International Symposium on Regulatory Peptides
Lundy, Fionnuala (Recipient), 2010
Prize: Prize (including medals and awards)
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PhD Student Jamie Toole (Principal Supervisor Dr F Lundy) won the Royal College of Surgeons in Ireland (RCSI) Clinical Prize
Lundy, Fionnuala (Recipient), 2014
Prize: Prize (including medals and awards)
Activities
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Efficacy and Mechanism Evaluation (EME) Programme (External organisation)
Fionnuala Lundy (Reviewer)
2019 → 2022Activity: Membership types › Membership of peer review panel or committee
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Hosting Lurgan College, Work Experience Student
Fionnuala Lundy (Host)
16 Jan 2019 → 18 Jan 2019Activity: Other activity types › Hosting a school group or open day
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International Association for Dental Research Annual Conference, London 2018
Fionnuala Lundy (Session chair)
25 Jul 2018 → 28 Jul 2018Activity: Participating in or organising an event types › Participation in conference
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Bob Pollard
Fionnuala Lundy (Host)
27 Mar 2018Activity: Hosting a visitor types › Hosting an academic visitor
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Durham University (External organisation)
Fionnuala Lundy (Board Member)
2018 → 2021Activity: Membership types › Membership of peer review panel or committee
Press / Media
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MATRIX NI Successful Women in Science
23/05/2018
1 Media contribution
Press/Media: Public Engagement Activities
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QUEEN’S COLLABORATIVE PROJECT WINS ASTHMA / COPD PROJECT OF THE YEAR
Lorraine Martin, Lorcan McGarvey & Fionnuala Lundy
28/02/2018
1 item of Media coverage
Press/Media: Research
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Urgent Call to Tackle Killer Disease on World COPD Day
Lorraine Martin, Lorcan McGarvey & Fionnuala Lundy
15/11/2017
1 Media contribution
Press/Media: Research
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QUEEN'S SECURES EU FUNDING FOR FIGHT AGAINST LUNG DISEASE
Lorraine Martin, Lorcan McGarvey & Fionnuala Lundy
26/01/2017
1 Media contribution
Press/Media: Research
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Article for Diabetes Wellness News (Lay Magazine, Diabetes Research & Wellness Foundation)
01/01/2011
1 Media contribution
Press/Media: Public Engagement Activities