1993 …2019

Research output per year

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Personal profile


I am interested in the Genetic Epidemiology of Psychosis and Substance Misuse. This involves using molecular and epidemiological approaches to look at the complex causal pathways for psychiatric illnes I am also interested in the overlap between movement disorder and psychiatric symptoms and the use of stratified medicine approaches to treatment of psychosis.I am a consultant Psychiatrist in the Belfast HSC Trust and am part of a resettlement team that is responsible for the community rehabilitation of patients with long term illness. I am interested in developing measures of Recovery in this group of Patients, we have been funded by the DHSSPSNI to do a Rapid Review of these measures. I have an interest in Creativity and Mental Health and have been part of a HTA funded trial of Art Therapy. I I'm a member of a Northern Ireland Public Health Research Network subgroup interested in Arts In Health


I teach and help organise the undergraduate medical course in Psychiatry. I have recently Produced a reportreviewing the  delivery of teaching at an undergraduate level in conjunction with a representative group of Psychatrists from Northern Ireland. We have produced a report with a number of suggestions  as a result of focus group work with undergraduates and Psychatrists. I also teach on the psychopharmacology course in third year.  I have organised aStudent Selected Component on Creativity and Mental illness.
I am the organiser  of the postgraduate Diploma in Mental Health, This is a course which is run twice a year and attract up to 60 Foundation year and GP trainees. Unlike other parts of the United Kingdom Northern Ireland does not have a recruitment problem in psychiaty. The undergraduate program and the postgraduate diploma are recognised as important factors in recruitment and retention.

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Research Output

A polygenic resilience score moderates the genetic risk for schizophrenia

Schizophrenia Working Group of the Psychiatric Genomics Consortium & O'Neill, F., 06 Sep 2019, In : Molecular Psychiatry. 16 p.

Research output: Contribution to journalArticle

Open Access
  • 100 Downloads (Pure)
  • Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

    CommonMind Consortium & O'Neill, F., 01 Apr 2019, In : Nature Genetics. 51, 4, p. 659-674 16 p.

    Research output: Contribution to journalArticle

  • 10 Citations (Scopus)

    Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

    Cross-Disorder Group of the Psychiatric Genomics Consortium. Electronic address: plee0@mgh.harvard.edu & O'Neill, F., 12 Dec 2019, In : Cell. 179, 7, p. 1469-1482.e11

    Research output: Contribution to journalArticle

  • 1 Citation (Scopus)



    Francis O'Neill (Member of programme committee)

    Activity: Participating in or organising an event typesParticipation in conference

    “Art for the senses”

    Francis O'Neill (Participant)
    29 Mar 2019

    Activity: Participating in or organising an event typesParticipation in workshop, seminar, course


    Francis O'Neill (Member of programme committee)
    Nov 2018

    Activity: Participating in or organising an event typesParticipation in conference

    British Medical Association (External organisation)

    Francis O'Neill (Advisor)

    Activity: Membership typesMembership of national or international committees and working groups

    Press / Media

    Mind over Matter Irish News Column

    Francis O'Neill


    1 Media contribution

    Press/Media: Other