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Research Output 1993 2019

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Article
2019
83 Downloads (Pure)

A polygenic resilience score moderates the genetic risk for schizophrenia

Schizophrenia Working Group of the Psychiatric Genomics Consortium & O'Neill, F., 06 Sep 2019, In : Molecular Psychiatry. 16 p.

Research output: Contribution to journalArticle

Open Access
File
Schizophrenia
Disease Resistance
Penetrance
Genomics
Psychiatry
10 Citations (Scopus)

Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

CommonMind Consortium & O'Neill, F., 01 Apr 2019, In : Nature Genetics. 51, 4, p. 659-674 16 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Prefrontal Cortex
Schizophrenia
Tay-Sachs Disease
Gene Expression
1 Citation (Scopus)

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Cross-Disorder Group of the Psychiatric Genomics Consortium. Electronic address: plee0@mgh.harvard.edu & O'Neill, F., 12 Dec 2019, In : Cell. 179, 7, p. 1469-1482.e11

Research output: Contribution to journalArticle

Psychiatry
Genes
Tourette Syndrome
Obsessive-Compulsive Disorder
Anorexia Nervosa
1 Citation (Scopus)

Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia

Wellcome Trust Case Control Consortium 2 & Schizophrenia Working Group of the Psychiatric Genomics Consortium, 01 Apr 2019, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 180, 3, p. 223-231

Research output: Contribution to journalArticle

Exome
Haplotypes
Genome-Wide Association Study
Schizophrenia
Population
70 Downloads (Pure)
Open Access
File
alcohol
Alcohols
Depression
Growth
adolescent
2018
4 Citations (Scopus)

Enhancing Psychosis-Spectrum Nosology Through an International Data Sharing Initiative

Docherty, A. R., Fonseca-Pedrero, E., Debbané, M., Chan, R. C. K., Linscott, R. J., Jonas, K. G., Cicero, D. C., Green, M. J., Simms, L. J., Mason, O., Watson, D., Ettinger, U., Waszczuk, M., Rapp, A., Grant, P., Kotov, R., DeYoung, C. G., Ruggero, C. J., Eaton, N. R., Krueger, R. F. & 25 others, Patrick, C., Hopwood, C., O'Neill, F. A., Zald, D. H., Conway, C. C., Adkins, D. E., Waldman, I. D., van Os, J., Sullivan, P. F., Anderson, J. S., Shabalin, A. A., Sponheim, S. R., Taylor, S. F., Grazioplene, R. G., Bacanu, S. A., Bigdeli, T. B., Haenschel, C., Malaspina, D., Gooding, D. C., Nicodemus, K., Schultze-Lutter, F., Barrantes-Vidal, N., Mohr, C., Carpenter, W. T. & Cohen, A. S., 16 May 2018, In : Schizophrenia Bulletin.

Research output: Contribution to journalArticle

Information Dissemination
Psychotic Disorders
Psychopathology
Psychiatry
Genomics
18 Citations (Scopus)

Estimation of Genetic Correlation via Linkage Disequilibrium Score Regression and Genomic Restricted Maximum Likelihood

Schizophrenia Working Group of the Psychiatric Genomics Consortium & O'Neill, F. A., 07 Jun 2018, In : The American Journal of Human Genetics. 102, 6, p. 1185-1194 10 p.

Research output: Contribution to journalArticle

Linkage Disequilibrium
Schizophrenia
Likelihood Functions
Genetic Heterogeneity
Nucleic Acid Regulatory Sequences
81 Citations (Scopus)

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium. Electronic address: douglas.ruderfer@vanderbilt.edu & O'Neill, F. A., 14 Jun 2018, In : Cell. 173, 7, p. 1705-1715.e16

Research output: Contribution to journalArticle

Dissection
Bipolar Disorder
Schizophrenia
Genes
Potassium
182 Downloads (Pure)
Open Access
File
Precision Medicine
Physicians
Psychiatry
Drug Prescriptions
Clinical Decision-Making
2017
234 Citations (Scopus)

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

Marshall, C. R., Howrigan, D. P., Merico, D., Thiruvahindrapuram, B., Wu, W., Greer, D. S., Antaki, D., Shetty, A., Holmans, P. A., Pinto, D., Gujral, M., Brandler, W. M., Malhotra, D., Wang, Z., Fajarado, K. V. F., Maile, M. S., Ripke, S., Agartz, I., Albus, M., Alexander, M. & 31 others, Amin, F., Atkins, J., Bacanu, S-A., Belliveau, R. A., Bergen, S. E., Bertalan, M., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Bulik-Sullivan, B. K., Byerley, W., Cahn, W., Cai, G., Cairns, M. J., Campion, D., Cantor, R. M., Carr, V. J., Carrera, N., Catts, S. V., Chambert, K. D., Cheng, W., Cloninger, C. R., Cohen, D., Cormican, P., Kavanagh, D., Murphy, K. C., O'Neill, F. & Psychosis Endophenotypes International Consortium, Jan 2017, In : Nature Genetics. 49, 1, p. 27-35 9 p.

Research output: Contribution to journalArticle

Schizophrenia
Odds Ratio
Genome
Homologous Recombination
Sample Size
36 Citations (Scopus)
98 Downloads (Pure)

Genetic correlation between amyotrophic lateral sclerosis and schizophrenia

McLaughlin, R. L., Schijven, D., van Rheenen, W., van Eijk, K. R., O'Brien, M., Kahn, R. S., Ophoff, R. A., Goris, A., Bradley, D. G., Al-Chalabi, A., van den Berg, L. H., Luykx, J. J., Hardiman, O., Veldink, J. H., Project MinE GWAS Consortium & O'Neill, F., 21 Mar 2017, In : Nature Communications. 8, p. 1-12 14774.

Research output: Contribution to journalArticle

Open Access
File
schizophrenia
Amyotrophic Lateral Sclerosis
Schizophrenia
Genes
genome

Monochrome - poems by doctors

O'Neill, F. A., May 2017, In : The British Journal of Psychiatry. 210, 5, p. 370 1 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Occurrence and co-occurrence of hallucinations by modality in schizophrenia-spectrum disorders

McCarthy-Jones, S., Smailes, D., Corvin, A., Gill, M., Morris, D. W., Dinan, T. G., Murphy, K. C., O'Neill, F. A., Waddington, J. L., Australian Schizophrenia Research Bank, Donohoe, G. & Dudley, R., Jun 2017, In : Psychiatry Research. 252, p. 154-160 7 p.

Research output: Contribution to journalArticle

Hallucinations
Schizophrenia
Touch
Ireland
Theoretical Models
2016
101 Citations (Scopus)

Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

Franke, B., Stein, J. L., Ripke, S., Anttila, V., Hibar, D. P., van Hulzen, K. J. E., Arias-Vasquez, A., Smoller, J. W., Nichols, T. E., Neale, M. C., McIntosh, A. M., Lee, P., McMahon, F. J., Meyer-Lindenberg, A., Mattheisen, M., Andreassen, O. A., Gruber, O., Sachdev, P. S., Roiz-Santiañez, R., Saykin, A. J. & 16 others, Ehrlich, S., Mather, K. A., Turner, J. A., Schwarz, E., Thalamuthu, A., Yao, Y., Ho, Y. Y. W., Martin, N. G., Wright, M. J., O'Donovan, M. C., Thompson, P. M., Neale, B. M., Medland, S. E., Sullivan, P. F., Schizophrenia Working Group of the Psychiatric Genomics Consortium & O'Neill, F., 2016, In : Nature Neuroscience. 19, 3, p. 420-31 12 p.

Research output: Contribution to journalArticle

Schizophrenia
Brain
Psychiatry
Phenotype
Genetic Markers
18 Citations (Scopus)

Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness

Bigdeli, T. B., Ripke, S., Bacanu, S-A., Lee, S. H., Wray, N. R., Gejman, P. V., Rietschel, M., Cichon, S., St Clair, D., Corvin, A., Kirov, G., McQuillin, A., Gurling, H., Rujescu, D., Andreassen, O. A., Werge, T., Blackwood, D. H. R., Pato, C. N., Pato, M. T., Malhotra, A. K. & 5 others, O'Donovan, M. C., Kendler, K. S., Fanous, A. H., Schizophrenia Working Group of the Psychiatric Genomics Consortium & O'Neill, F., Mar 2016, In : American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. 171, 2, p. 276-89 14 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Schizophrenia
Single Nucleotide Polymorphism
Genome
Genomics
178 Downloads (Pure)
Open Access
File
Psychiatry
Therapeutics
Genotype
14 Citations (Scopus)

Meta-analysis of Positive and Negative Symptoms Reveals Schizophrenia Modifier Genes

Edwards, A. C., Bigdeli, T. B., Docherty, A. R., Bacanu, S., Lee, D., de Candia, T. R., Moscati, A., Thiselton, D. L., Maher, B. S., Wormley, B. K., Walsh, D., O'Neill, F. A., Kendler, K. S., Riley, B. P. & Fanous, A. H., 2016, In : Schizophrenia Bulletin. 42, 2, p. 279-287 9 p.

Research output: Contribution to journalArticle

Modifier Genes
Meta-Analysis
Schizophrenia
Gene Ontology
Genome-Wide Association Study
737 Citations (Scopus)

Schizophrenia risk from complex variation of complement component 4

Sekar, A., Bialas, A. R., de Rivera, H., Davis, A., Hammond, T. R., Kamitaki, N., Tooley, K., Presumey, J., Baum, M., Van Doren, V., Genovese, G., Rose, S. A., Handsaker, R. E., Daly, M. J., Carroll, M. C., Stevens, B., McCarroll, S. A., Schizophrenia Working Group of the Psychiatric Genomics Consortium & O'Neill, F., 11 Feb 2016, In : Nature. 530, 7589, p. 177-83 7 p.

Research output: Contribution to journalArticle

Complement C4
Schizophrenia
Synapses
Alleles
Brain
2 Citations (Scopus)
136 Downloads (Pure)
Open Access
File
Psychiatry
Genotype
Therapeutics
Schizophrenia
Weights and Measures
2015
89 Citations (Scopus)
197 Downloads (Pure)

Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci

The Psychiatric Genomics Consortium (PGC) Bipolar Disorder and Schizophrenia Work Groups & The International Multiple Sclerosis Genetics Consortium (IMSGC), 2015, In : Molecular Psychiatry. 20, p. 207-214

Research output: Contribution to journalArticle

Open Access
File
Genetic Pleiotropy
Bipolar Disorder
Multiple Sclerosis
Schizophrenia
Genes
8 Citations (Scopus)

Genome-wide gene pathway analysis of psychotic illness symptom dimensions based on a new schizophrenia-specific model of the OPCRIT

Docherty, A. R., Bigdeli, T. B., Edwards, A. C., Bacanu, S., Lee, D., Neale, M. C., Wormley, B. K., Walsh, D., O'Neill, F. A., Riley, B. P., Kendler, K. S. & Fanous, A. H., May 2015, In : Schizophrenia research. 164, 1-3, p. 181-186 6 p.

Research output: Contribution to journalArticle

Schizophrenia
Genome
Statistical Factor Analysis
Genes
Gene Ontology
794 Citations (Scopus)

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

Bulik-Sullivan, B. K., Loh, P-R., Finucane, H. K., Ripke, S., Yang, J., Patterson, N., Daly, M. J., Price, A. L., Neale, B. M., Schizophrenia Working Group of the Psychiatric Genomics Consortium & O'Neill, F., Mar 2015, In : Nature Genetics. 47, 3, p. 291-5 5 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Linkage Disequilibrium
Economic Inflation
Sample Size
Population
180 Citations (Scopus)

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

Vilhjálmsson, B. J., Yang, J., Finucane, H. K., Gusev, A., Lindström, S., Ripke, S., Genovese, G., Loh, P-R., Bhatia, G., Do, R., Hayeck, T., Won, H-H., Kathiresan, S., Pato, M., Pato, C., Tamimi, R., Stahl, E., Zaitlen, N., Pasaniuc, B., Belbin, G. & 16 others, Kenny, E. E., Schierup, M. H., De Jager, P., Patsopoulos, N. A., McCarroll, S., Daly, M., Purcell, S., Chasman, D., Neale, B., Goddard, M., Visscher, P. M., Kraft, P., Patterson, N., Price, A. L., Schizophrenia Working Group of the Psychiatric Genomics Consortium & O'Neill, F., 01 Oct 2015, In : The American Journal of Human Genetics. 97, 4, p. 576-92 17 p.

Research output: Contribution to journalArticle

Linkage Disequilibrium
Sample Size
Schizophrenia
Multiple Sclerosis
Datasets
2014
19 Citations (Scopus)

An inherited duplication at the gene p21 Protein-Activated Kinase 7 (PAK7) is a risk factor for psychosis

Welcome Trust Case Control Consortium 2, 15 Jun 2014, In : Human Molecular Genetics. 23, 2, p. 3316-3326 11 p.

Research output: Contribution to journalArticle

p21-Activated Kinases
Psychotic Disorders
Protein Kinases
Schizophrenia
Bipolar Disorder
3135 Citations (Scopus)

Biological insights from 108 schizophrenia-associated genetic loci

Schizophrenia Working Group of the Psychiatric Genomics Consortium & O'Neill, F., 24 Jul 2014, In : Nature. 511, 7510, p. 421-427 7 p.

Research output: Contribution to journalArticle

Genetic Loci
Schizophrenia
Genome-Wide Association Study
Genes
Alleles
3 Citations (Scopus)
150 Downloads (Pure)

Clozapine-induced liver injury and pleural effusion

Kane, J. P. M. & O'Neill, F. A., 08 Sep 2014, In : Mental illness. 6, 2, p. 36-37 2 p.

Research output: Contribution to journalArticle

Open Access
File
Clozapine
Pleural Effusion
Liver
Wounds and Injuries
Hepatitis
63 Citations (Scopus)
5 Downloads (Pure)

Common variant at 16p11.2 conferring risk of psychosis

Steinberg, S., de Jong, S., Mattheisen, M., Costas, J., Demontis, D., Jamain, S., Pietiläinen, O. P. H., Lin, K., Papiol, S., Huttenlocher, J., Sigurdsson, E., Vassos, E., Giegling, I., Breuer, R., Fraser, G., Walker, N., Melle, I., Djurovic, S., Agartz, I., Tuulio-Henriksson, A. & 31 others, Suvisaari, J., Lönnqvist, J., Paunio, T., Olsen, L., Hansen, T., Ingason, A., Pirinen, M., Strengman, E., Hougaard, D. M., Orntoft, T., Didriksen, M., Hollegaard, M. V., Nordentoft, M., Abramova, L., Kaleda, V., Arrojo, M., Sanjuán, J., Arango, C., Etain, B., Bellivier, F., Méary, A., Schürhoff, F., Szoke, A., Ribolsi, M., Magni, V., Siracusano, A., Sperling, S., Rossner, M., Christiansen, C., O'Neill, F. A. & GROUP, Jan 2014, In : Molecular Psychiatry. 19, 1, p. 108-114 7 p.

Research output: Contribution to journalArticle

Psychotic Disorders
Schizophrenia
Bipolar Disorder
Body Mass Index
Genome
22 Citations (Scopus)

Epigenome-Wide Association Study for Parkinson's Disease

Moore, K., McKnight, A. J., Craig, D. & O'Neill, F., Dec 2014, In : NeuroMolecular Medicine. 16, 4, p. 845-855

Research output: Contribution to journalArticle

Parkinson Disease
Methylation
Anxiety
Genes
Phenotype
70 Citations (Scopus)
143 Downloads (Pure)

Evidence that duplications of 22q11.2 protect against schizophrenia

Rees, E., Kirov, G., Sanders, A., Walters, J. T. R., Chambert, K. D., Shi, J., Szatkiewicz, J., O'Dushlaine, C., Richards, A. L., Green, E. K., Jones, I., Davies, G., Legge, S. E., Moran, J. L., Pato, C., Pato, M., Genovese, G., Levinson, D., Duan, J., Moy, W. & 17 others, Göring, H. H. H., Morris, D., Cormican, P., Kendler, K. S., O'Neill, F. A., Riley, B., Gill, M., Corvin, A., Wellcome Trust Case Control Consortium, Craddock, N., Sklar, P., Hultman, C., Sullivan, P. F., Gejman, P. V., McCarroll, S. A., O'Donovan, M. C. & Owen, M. J., Jan 2014, In : Molecular Psychiatry. 19, p. 37-40 4 p.

Research output: Contribution to journalArticle

Open Access
File
Schizophrenia
Phenotype
Mutation
Population
Chromosome 22q11.2 Microduplication Syndrome
7 Citations (Scopus)

No evidence that runs of homozygosity are associated with schizophrenia in an Irish genome-wide association dataset

Heron, E. A., Cormican, P., Donohoe, G., O'Neill, F. A., Kendler, K. S., Riley, B. P., Wellcome Trust Case Control Consortium 2, Gill, M., Corvin, A. P. & Morris, D. W., Apr 2014, In : Schizophrenia research. 154, 1-3, p. 79-82 4 p.

Research output: Contribution to journalArticle

Schizophrenia
Genome
Haplotypes
Genome-Wide Association Study
Single Nucleotide Polymorphism
250 Citations (Scopus)

Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases

Gusev, A., Hong Lee, S., Trynka, G., Finucane, H., Vilhjálmsson, B. J., Xu, H., Zang, C., Ripke, S., Bulik-Sullivan, B., Stahl, E., Schizophrenia Working Group of the Psychiatric Genomics Consortium, O'Neill, F., Kähler, A. K., Hultman, C. M., Purcell, S. M., McCarroll, S. A., Daly, M., Pasaniuc, B., Sullivan, P. F., Neale, B. M. & 3 others, Wray, N. R., Raychaudhuri, S. & Price, A. L., 06 Nov 2014, In : The American Journal of Human Genetics. 95, 5, p. 535-552 18 p.

Research output: Contribution to journalArticle

Single Nucleotide Polymorphism
Genome-Wide Association Study
Hypersensitivity
Exome
Linkage Disequilibrium
20 Citations (Scopus)

Variability inworking memory performance explained by epistasis vs polygenic scores in the ZNF804A pathway

tony O'neill, 01 Jul 2014, In : JAMA Psychiatry. 71, 7, p. 778-785 8 p.

Research output: Contribution to journalArticle

Psychotic Disorders
Cognition
Schizophrenia
Single Nucleotide Polymorphism
Genome-Wide Association Study
2013
14 Citations (Scopus)
349 Downloads (Pure)

Association Study of 167 Candidate Genes for Schizophrenia Selected by a Multi-Domain Evidence-Based Prioritization Algorithm and Neurodevelopmental Hypothesis

Zhao, Z., Webb, B. T., Jia, P., Bigdeli, T. B., Maher, B. S., van den Oord, E., Bergen, S. E., Amdur, R. L., O'Neill, F. A., Walsh, D., Thiselton, D. L., Chen, X., Pato, C. N., The International Schizophrenia Consortium, Riley, B. P., Kendler, K. S. & Fanous, A. H., 29 Jul 2013, In : PLoS ONE. 8, 7, p. 1-8 8 p., e67776.

Research output: Contribution to journalArticle

Open Access
File
prioritization
Genetic Association Studies
Schizophrenia
Genes
neurodevelopment
47 Citations (Scopus)

CNV analysis in a large schizophrenia sample implicates deletions at 16p12.1 and SLC1A1 and duplications at 1p36.33 and CGNL1

Rees, E., Walters, J. T. R., Chambert, K. D., O'Dushlaine, C., Szatkiewicz, J., Richards, A. L., Georgieva, L., Mahoney-Davies, G., Legge, S. E., Moran, J. L., Genovese, G., Levinson, D., Morris, D. W., Cormican, P., Kendler, K. S., O'Neill, F. A., Riley, B., Gill, M., Corvin, A., Wellcome Trust Case Control Consortium & 10 others, Sklar, P., Hultman, C., Pato, C., Pato, M., Sullivan, P. F., Gejman, P. V., McCarroll, S. A., O'Donovan, M. C., Owen, M. J. & Kirov, G., 26 Oct 2013, In : Human Molecular Genetics. 23, 6, p. 1669-1676

Research output: Contribution to journalArticle

Schizophrenia
Genes
872 Citations (Scopus)

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

Ripke, S., O'Dushlaine, C., Chambert, K., Moran, J. L., Kähler, A. K., Akterin, S., Bergen, S. E., Collins, A. L., Crowley, J. J., Fromer, M., Kim, Y., Lee, S. H., Magnusson, P. K. E., Sanchez, N., Stahl, E. A., Williams, S., Wray, N. R., Xia, K., Bettella, F., Borglum, A. D. & 31 others, Bulik-Sullivan, B. K., Cormican, P., Craddock, N., de Leeuw, C., Durmishi, N., Gill, M., Golimbet, V., Hamshere, M. L., Holmans, P., Hougaard, D. M., Kendler, K. S., Lin, K., Morris, D. W., Mors, O., Mortensen, P. B., Neale, B. M., O'Neill, F. A., Owen, M. J., Milovancevic, M. P., Posthuma, D., Powell, J., Richards, A. L., Riley, B. P., Ruderfer, D., Rujescu, D., Sigurdsson, E., Silagadze, T., Smit, A. B., Stefansson, H., O'Neill, F. A. & Multicenter Genetic Studies of Schizophrenia Consortium, 25 Aug 2013, In : Nature Genetics. 45, p. 1150-1159

Research output: Contribution to journalArticle

Genome-Wide Association Study
Schizophrenia
Single Nucleotide Polymorphism
Calcium Signaling
Bipolar Disorder

Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC

Hamshere, M. L., Walters, J. T. R., Smith, R., Richards, A. L., Green, E., Grozeva, D., Jones, I., Forty, L., Jones, L., Gordon-Smith, K., Riley, B., O'Neill, T., Kendler, K. S., Sklar, P., Purcell, S., Kranz, J., Morris, D., Gill, M., Holmans, P., Craddock, N. & 3 others, Corvin, A., Owen, M. J. & O'Donovan, M. C., 2013, In : Molecular Psychiatry. 18, p. 708-712 5 p.

Research output: Contribution to journalArticle

Schizophrenia
Genome
Single Nucleotide Polymorphism
Bipolar Disorder
Major Histocompatibility Complex
149 Citations (Scopus)

Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC

Hamshere, M. L., Walters, J. T. R., Smith, R., Richards, A. L., Green, E., Grozeva, D., Jones, I., Forty, L., Jones, L., Gordon-Smith, K., Riley, B., O'Neill, F. A., O'Neill, T., Kendler, K. S., Sklar, P., Purcell, S., Kranz, J., Morris, D., Gill, M., Holmans, P. & 5 others, Craddock, N., Corvin, A., Owen, M. J., O'Donovan, M. C. & Schizophrenia Psychiatric Genome-wide Association Study Consortium, Jun 2013, In : Molecular Psychiatry. 18, 6, p. 708-12 5 p.

Research output: Contribution to journalArticle

Schizophrenia
Genome
Single Nucleotide Polymorphism
Bipolar Disorder
Major Histocompatibility Complex
47 Citations (Scopus)

Implication of a rare deletion at distal 16p11.2 in schizophrenia

Guha, S., Rees, E., Darvasi, A., Ivanov, D., Ikeda, M., Bergen, S. E., Magnusson, P. K., Cormican, P., Morris, D., Gill, M., Cichon, S., Rosenfeld, J. A., Lee, A., Gregersen, P. K., Kane, J. M., Rietschel, M., Nöthen, M. M., Degenhardt, F., Priebe, L., Breuer, R. & 25 others, Strohmaier, J., Ruderfer, D. M., Moran, J. L., Chambert, K. D., Sanders, A. R., Shi, J., Kendler, K., Riley, B., O'Neill, T., Walsh, D., Malhotra, D., Corvin, A., Purcell, S., Sklar, P., Iwata, N., Hultman, C. M., Sullivan, P. F., Sebat, J., McCarthy, S., Gejman, P. V., Levinson, D. F., Owen, M. J., O'Donovan, M. C., Lencz, T. & Kirov, G., 2013, In : JAMA Psychiatry. 70, 3, p. 253-260 8 p.

Research output: Contribution to journalArticle

Schizophrenia
Psychotic Disorders
Bulgaria
Genetic Association Studies
Autistic Disorder
24 Citations (Scopus)

Molecular Validation of the Schizophrenia Spectrum

Bigdeli, T. B., Bacanu, S-A., Webb, B. T., Walsh, D., O'Neill, F. A., Fanous, A. H., Riley, B. P. & Kendler, K. S., 22 Aug 2013, In : Schizophrenia Bulletin. 40, 1, p. 60-65

Research output: Contribution to journalArticle

Schizophrenia
Genome-Wide Association Study
Psychiatry
Specific Gravity
Population Control
52 Citations (Scopus)
246 Downloads (Pure)

Mood congruent psychotic symptoms and specific cognitive deficits in carriers of the novel schizophrenia risk variant at MIR-137

Cummings, E., Donohoe, G., Hargreaves, A., Moore, S., Fahey, C., Dinan, T. G., McDonald, C., O'Callaghan, E., O'Neill, F. A., Waddington, J. L., Murphy, K. C., Morris, D. W., Gill, M. & Corvin, A., 04 Jan 2013, In : Neuroscience Letters. 532, 1, p. 33-38 6 p.

Research output: Contribution to journalArticle

Open Access
File
Neurobehavioral Manifestations
Schizophrenia
Psychotic Disorders
Single Nucleotide Polymorphism
Alleles
26 Citations (Scopus)

Schizophrenia genetic variants are not associated with intelligence

Psychiatric Genome-Wide Association Study (GWAS) Consortium, Ophoff, R. A., Kahn, R. S. & O'Neill, F. A., Dec 2013, In : Psychological Medicine. 43, 12, p. 2563-2570 8 p.

Research output: Contribution to journalArticle

Intelligence
Schizophrenia
Single Nucleotide Polymorphism
Genome-Wide Association Study
Psychiatry
2012
4 Citations (Scopus)

Concordance between chart review and structured interview assessments of schizophrenic symptoms

Fanous, A. H., Amdur, R. L., O'Neill, F. A., Walsh, D. & Kendler, K. S., Apr 2012, In : Comprehensive psychiatry. 53, 3, p. 275-9 5 p.

Research output: Contribution to journalArticle

Symptom Assessment
Interviews
Statistical Factor Analysis
Schizophrenia
Hallucinations
92 Citations (Scopus)

Genome-wide Association Study Implicates HLA-C*01:02 as a Risk Factor at the Major Histocompatibility Complex Locus in Schizophrenia

Irish Schizophrenia Genomics Consortium & the Wellcome Trust Case Control Consortium 2 & O'Neill, F. A., 15 Oct 2012, In : Biological Psychiatry. 72, 8, p. 620-628 9 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
HLA Antigens
Major Histocompatibility Complex
Single Nucleotide Polymorphism
Schizophrenia
45 Citations (Scopus)

Genome-Wide Association Study of Multiplex Schizophrenia Pedigrees

Levinson, D. F., Shi, J., Wang, K., Oh, S., Riley, B., Pulver, A. E., Wildenauer, D. B., Laurent, C., Mowry, B. J., Gejman, P. V., Owen, M. J., Kendler, K. S., Nestadt, G., Schwab, S. G., Mallet, J., Nertney, D., Sanders, A. R., Williams, N. M., Wormley, B., Lasseter, V. K. & 27 others, Albus, M., Godard-Bauché, S., Alexander, M., Duan, J., O'Donovan, M. C., Walsh, D., O'Neill, F., Papadimitriou, G. N., Dikeos, D., Maier, W., Lerer, B., Campion, D., Cohen, D., Jay, M., Fanous, A., Eichhammer, P., Silverman, J. M., Norton, N., Zhang, N., Hakonarson, H., Gao, C., Citri, A., Hansen, M., Ripke, S., Gwas Consortium, T. S. P., Dudbridge, F. & Holmans, P. A., 01 Aug 2012, In : American Journal of Psychiatry. 169, 9, p. 963-973 11 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Pedigree
Schizophrenia
Single Nucleotide Polymorphism
Psychiatry
32 Citations (Scopus)

Group art therapy as an adjunctive treatment for people with schizophrenia: a randomised controlled trial (MATISSE).

Crawford, M. J., Killaspy, H., Barnes, T. R., Barrett, B., Byford, S., Clayton, K., Dinsmore, J., Floyd, S., Hoadley, A., Johnson, T., Kalaitzaki, E., King, M., Leurent, B., Maratos, A., O'Neill, F. A., Osborn, D., Patterson, S., Soteriou, T., Tyrer, P., Waller, D. & 1 others, MATISSE project team, P. T., 2012, In : Health technology assessment (Winchester, England). 16, 8, p. iii-iv, 1-76

Research output: Contribution to journalArticle

Open Access
Art Therapy
Group Psychotherapy
Schizophrenia
Randomized Controlled Trials
Costs and Cost Analysis
67 Citations (Scopus)
141 Downloads (Pure)

Group art therapy as an adjunctive treatment for people with schizophrenia: multicentre pragmatic randomised trial

Crawford, M. J., Killaspy, H., Barnes, T. R. E., Barrett, B., Byford, S., Clayton, K., Dinsmore, J., Floyd, S., Hoadley, A., Johnson, T., Kalaitzaki, E., King, M., Leurent, B., Maratos, A., O'Neill, F. A., Osborn, D. P., Patterson, S., Soteriou, T., Tyrer, P., Waller, D. & 1 others, MATISSE project team, 10 Mar 2012, In : British Medical Journal. 344, 7847, 9 p., E846.

Research output: Contribution to journalArticle

Open Access
File
Pragmatic Clinical Trials
Art Therapy
Group Psychotherapy
Schizophrenia
Therapeutics
2011
4 Citations (Scopus)

Comprehensive gene-based association study of a chromosome 20 linked region implicates novel risk loci for depressive symptoms in psychotic illness

Bigdeli, T. B., Maher, B. S., Zhao, Z., Oord, E. J. C. G. V. D., Thiselton, D. L., Sun, J., Webb, B. T., Amdur, R. L., Wormley, B., O'Neill, F. A., Walsh, D., Riley, B. P., Kendler, K. S. & Fanous, A. H., 2011, In : PloS one. 6, 12, p. e21440

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 20
Chromosomes
Genes
Association reactions
Depression
1235 Citations (Scopus)

Genome-wide association study identifies five new schizophrenia loci

Ripke, S., Sklar, P., Rossin, L., Ruderfer, D. M., Bergen, S. E., Daly, M. J., Sanders, A. R., Duan, J., Gejman, P. V., Kendler, K. S., Maher, B. S., Ribble, R., Riley, B. P., Wormley, B., Fanous, A., Levinson, D. F., Alexander, M., Silverman, J. M., Holmans, P. A., Craddock, N. & 176 others, Dwyer, S., Georgieva, L., Hamshere, M., Kirov, G. K., Moskvina, V., Nikolov, I., Norton, N., Owen, M. J., Williams, H. J., Williams, N. M., Zammit, S., O'Donovan, M. C., Lin, D-Y., Ophoff, R. A., Strengman, E., Cantor, R. M., Freimer, N. B., Andreassen, O. A., Agartz, I., Djurovic, S., Mattingsdal, M., Melle, I., Scolnick, E., Purcell, S., Neale, B. M., Cichon, S., Mattheisen, M., Nöthen, M. M., St. Clair, D., Corvin, A., Cormican, P., Donohoe, G., Gill, M., Kenny, E., Morris, D. W., O'Dushlaine, C. T., Quinn, E. M., Gurling, H., Bass, N., Choudhury, K., Datta, S., Krasucki, R., Lawrence, J., McQuillin, A., Pimm, J., Puri, V., Werge, T., Duong, L., Hansen, T., Ingason, A., Jakobsen, K. D., Olsen, L., Rasmussen, H. B., Thygesen, J. H., Rujescu, D., Friedl, M., Giegling, I., Hartmann, A. M., Konnerth, H., Konte, B., Blackwood, D. H. R., MacLean, A. W., Malloy, P., McGhee, K. A., McIntosh, A., Pato, C. N., Pato, M. T., Malhotra, A. K., Lencz, T., Dudbridge, F., Visscher, P. M., Posthuma, D., Amdur, R. L., Stefansson, H., Steinberg, S., Stefansson, K., Mowry, B. J., McGrath, J. J., Nertney, D. A., Golimbet, V., De Hert, M., Van Winkel, R., Jönsson, E. G., Terenius, L., Bitter, I., Réthelyi, J. M., Pietiläinen, O. P. H., Peltonen, L., Collier, D. A., Tosato, S., Ruggeri, M., Albus, M., Amin, F., Black, D. W., Børglum, A. D., Demontis, D., Mors, O., Brown, M. A., Danoy, P. A., Bruggeman, R., Wiersma, D., Buccola, N. G., Byerley, W. F., Cahn, W., Kahn, R. S., Carr, V. J., Catts, S. V., Cloninger, C. R., De Haan, L., Linszen, D. H., Dikeos, D., Papadimitriou, G., Donnelly, P., Spencer, C. C. A., Strange, A., Fink-Jensen, A., Freedman, R., Olincy, A., Glenthøj, B., Godard, S., Hansen, M., Henskens, F. A., Hougaard, D. M., Hultman, C. M., Lichtenstein, P., Sullivan, P. F., Jablensky, A. V., Jay, M., Laurent, C., Jürgens, G., Keller, M. C., Kenis, G., Kim, Y., Krabbendam, L., Myin-Germeys, I., Van Os, J., Lasseter, V. K., Nestadt, G., Pulver, A. E., Lerer, F. B., Liang, K-Y., Lieberman, J. A., Stroup, T. S., Lönnqvist, J., Suvisaari, J., Loughland, C. M., Maier, W., Rietschel, M., Mallet, J., McLean, D. E., Michie, P. T., Schall, U., Milanova, V., Mortensen, P. B., Muglia, P., Nielsen, J., Nordentoft, M., O'Neill, F. A., Ørntoft, T. F., Pantelis, C., Petursson, H., Sigurdsson, E., Pickard, B., Quested, D., Schulze, T. G., Schwab, S. G., Wildenauer, D. B., Scott, R. J., Shi, J., Thirumalai, S., Timm, S., Toncheva, D., Van Den Oord, E., Veldink, J., Walsh, D. & Wang, A. G., Oct 2011, In : Nature Genetics. 43, 10, p. 969-976 8 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Schizophrenia
MicroRNAs
Genome
Internal-External Control
171 Citations (Scopus)

THE GENETIC BASIS OF NEUROPSYCHIATRIC SYMPTOMS IN PARKINSON'S DISEASE

Moore, K., Johnston, J., O'Neill, F., Passmore, P., Ross, O., Lynch, T., Mulcahy, R. & Craig, D., 2011, In : Irish journal of medical science. 180, p. 60-60 1 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Two non-synonymous markers in PTPN21, identified by genome-wide association study data-mining and replication, are associated with schizophrenia

Chen, J., Lee, G., Fanous, A. H., Zhao, Z., Jia, P., O'Neill, A., Walsh, D., Kendler, K. S., Chen, X., International Schizophrenia Consortium & O'Neill, F., Sep 2011, In : Schizophrenia research. 131, 1-3, p. 43-51 9 p.

Research output: Contribution to journalArticle

Data Mining
Genome-Wide Association Study
Schizophrenia
Linkage Disequilibrium
Haplotypes