20012018

Research output per year

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Research Output

2018

Mechanistic Insights into Colorectal Cancer Phenomics from Fundamental and Organotypic Model Studies

Campbell, F. C., Loughrey, M. B., McClements, J., Deevi, R. K., Javadi, A. & Rainey, L., 01 Sep 2018, In : The American journal of pathology. 188, 9, p. 1936-1948

Research output: Contribution to journalReview article

Open Access
File
3 Citations (Scopus)
212 Downloads (Pure)

Protein kinase C zeta suppresses low- or high-grade colorectal cancer (CRC) phenotypes by interphase centrosome anchoring

Deevi, R. K., Javadi, A., McClements, J., Vohhodina, J., Savage, K., Loughrey, M. B., Evergren, E. & Campbell, F. C., 09 Mar 2018, In : Journal of Pathology. p. 1-15

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
186 Downloads (Pure)
2017

PTEN 1 controls glandular morphogenesis through a juxtamembrane 2 β-Arrestin1/ARHGAP21 scaffolding complex

Javadi, A., Deevi, R. K., Evergren, E., Blondel-Tepaz, E., Baillie, G. S., Scott, M. G. H. & Campbell, F. C., 27 Jul 2017, In : eLife. 6, e24578

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
179 Downloads (Pure)
2016

Vitamin D3 suppresses morphological evolution of the cribriform cancerous phenotype

Deevi, R., McClements, J., McCloskey, K. D., Fatehullah, A., Tkocz, D., Javadi, A., Higginson, R., Durban, V. M., Jansen, M., Clarke, A., Loughrey, M. & Campbell, F., 02 Aug 2016, In : Oncotarget. 7, 31, p. 49042-49064

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
337 Downloads (Pure)
2014

Functional and genetic analysis of the colon cancer network

Emmert-Streib, F., de Matos Simoes, R., Glazko, G., McDade, S., Haibe-Kains, B., Holzinger, A., Dehmer, M. & Campbell, F. C., 16 May 2014, In : BMC Bioinformatics. 15 , Suppl 6, 15 p.

Research output: Contribution to journalArticle

Open Access
File
21 Citations (Scopus)
202 Downloads (Pure)
2013

PTEN Phosphatase-Independent Maintenance of Glandular Morphology in a Predictive Colorectal Cancer Model System

Jagan, I. C., Deevi, R. K., Fatehullah, A., Rebecca, T., Joshua, E., Michael, S., Loughrey, M., Arthur, K. & Campbell, F., Nov 2013, In : Neoplasia . 15, 11, p. 1218-1230 13 p.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
318 Downloads (Pure)
2012

Rescue of glandular dysmorphogenesis in PTEN-deficient colorectal cancer epithelium by PPARγ-targeted therapy

Jagan, I., Fatehullah, A., Deevi, R., Bingham, V. & Campbell, F., 30 Apr 2012, In : Oncogene. 32, null, p. 1305–1315

Research output: Contribution to journalArticle

13 Citations (Scopus)
2011
19 Citations (Scopus)

Enhanced lymphocyte interferon (IFN)-γ responses in a PTEN mutation-negative Cowden disease kindred.

Stevenson, R., Fatehullah, A., Bingham, V., Deevi, R., Jagan, I., Irvine, A., Armstrong, M., Morrison, P., Dimmick, I., Stewart, R. & Campbell, F., May 2011, In : Clinical and experimental immunology. 164(2), 2, p. 202-210 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

PTEN regulates colorectal epithelial apoptosis through Cdc42 signalling.

Deevi, R., Fatehullah, A., Jagan, I., Nagaraju, M., Bingham, V. & Campbell, F., 25 Oct 2011, In : British Journal of Cancer. 105, 9, p. 1313-1321 9 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2010

Apc(MIN) modulation of vitamin D secosteroid growth control

Xu, H., Posner, G. H., Stevenson, M. & Campbell, F. C., 20 Aug 2010, In : Carcinogenesis. 31, 8, p. 1434-1441 8 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Interferon-induced transmembrane 3 binds osteopontin in vitro: expressed in vivo IFITM3 reduced OPN expression

El-Tanani, M., Jin, D., Campbell, F. C. & Johnston, P. G., Feb 2010, In : Oncogene. 29, 5, p. 752-762 11 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Isolation and culture of mouse intestinal cells.

Campbell, F., 2010, In : Methods in Molecular Biology . 633, p. 197-206 10 p., 20204629.

Research output: Contribution to journalArticle

9 Citations (Scopus)
68 Citations (Scopus)
2009

Vitamin D Receptor Modulates the Neoplastic Phenotype Through Antagonistic Growth Regulatory Signals

Xu, H., McCann, M., Zhang, Z., Posner, G. H., Bingham, V., El-Tanani, M. E-T. & Campbell, F., Aug 2009, In : Molecular Carcinogenesis. 48, 8, p. 758-772 15 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)
2008

Agelastatin A: a novel inhibitor of osteopontin-mediated adhesion, invasion, and colony formation

Mason, C. K., McFarlane, S., Johnston, P., Crowe, P., Erwin, P. J., Domostoj, M. M., Campbell, F., Manaviazar, S., Hale, K. J. & El-Tanani, M., 01 Mar 2008, In : Molecular Cancer Therapeutics. 7, 3, p. 548-558 11 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

RAN GTPase is an effector of the invasive/metastatic phenotype induced by osteopontin.

Kurisetty, V. V., Johnston, P. G., Johnston, N., Erwin, P., Crowe, P., Fernig, D. G., Campbell, F. C., Anderson, I. P., Rudland, P. S. & El-Tanani, M., 04 Dec 2008, In : Oncogene. 27, 57, p. 7139-7149 11 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)
2006

BRCA1 Suppresses Osteopontin-mediated Breast Cancer

El-Tanani, M., Campbell, F., Crowe, P., Erwin, P., Harkin, P., Pharoah, P., Ponder, B. & Rudland, P. S., 08 Sep 2006, In : Journal of Biological Chemistry. 281(36), 36, p. 26587-26601 15 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Identification of apolipoprotein D as a novel inhibitor of osteopontin-induced neoplastic transformation.

Jin, D., El-Tanani, M. & Campbell, F., Dec 2006, In : International journal of oncology. 29, 6, p. 1591-1599 9 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Methylprednisolone Increases Urinary Nitrate Concentrations and Reduces Subclinical Renal Injury During Infrarenal Aortic Ischemia Reperfusion.

Baker, R. C., Armstrong, M., Young, I. S., O'Rourke, D., Barros D'Sa, A. A. B., McBride, W. T. & Campbell, F., Nov 2006, In : Annals of Surgery. 244(5), 5, p. 821-826 6 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Overexpression of p65/RelA potentiates curcumin-induced apoptosis in HCT116 human colon cancer cells.

Collett, G. & Campbell, F., Feb 2006, In : Carcinogenesis. 27(6), 6, p. 1285-1291 7 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

The drosophila ortholog of the endolysosomal membrane protein, endolyn, regulates cell proliferation.

Zhou, G-Q., Zhang, Y., D.J, F., S, C., A, R-L., Campbell, F. & S.M, W., 01 Dec 2006, In : Journal of Cellular Biochemistry. 99(5), 5, p. 1380-1396 17 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

The regulation and role of osteopontin in malignant transformation and cancer.

El-Tanani, M., Campbell, F., Kurisetty, V., Jin, D., McCann, M. & Rudland, P. S., Dec 2006, In : Cytokine. 17(6), 6, p. 463-474 12 p.

Research output: Contribution to journalArticle

134 Citations (Scopus)
2005

Chemopreventive properties of curcumin.

Campbell, F. & Collett, G., Jun 2005, In : Future oncology (London, England). 1(3), 3, p. 405-414 10 p.

Research output: Contribution to journalArticle

69 Citations (Scopus)

Homeostatic regulation of zinc transporters in the human small intestine by dietary zinc supplementation.

Campbell, F., Apr 2005, In : Gut. 54(4), 4, p. 469-478 10 p.

Research output: Contribution to journalArticle

79 Citations (Scopus)

Metallothionein crypt-restricted immunopositivity indices (MTCRII) correlate with aberrant crypt foci (ACF) in mouse colon

Donnelly, E., Bardwell, H., Thomas, G., Williams, E. D., Hoper, M., Crowe, P., McCluggage, W. G., Stevenson, M., Phillips, D. H., Hewer, A., Osborne, M. R. & Campbell, F., 20 May 2005, In : British Journal of Cancer. 92(12), 12, p. 2160-2165 6 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Total Synthesis and Mechanism of Action Studies on the Antitumor Alkaloid (-)-Agelastatin A

Hale, K., El-Tanani, M. E-T., Campbell, F., Mason, C. & Domostoj, M. M., 2005, Strategies and Tactics in Organic Synthesis Volume 6. Harmata, M. (ed.). Elsevier, p. 352-394 43 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

18 Citations (Scopus)
2004

Curcumin induces c-jun N-terminal kinase-dependent apoptosis in HCT116 human colon cancer cells.

Collett, G. & Campbell, F., Jul 2004, In : Carcinogenesis. 25(11), 11, p. 2183-2189 7 p.

Research output: Contribution to journalArticle

154 Citations (Scopus)

Duodeno-oesophageal reflux promotes epithelial proliferation, neoplastic change and enhances tumour formation induced by a human dietary carcinogen

Bonde, P., Menezes, A., Bell, Z., Mirvish, S., Sloan, J., McKeown, S., Robson, T., Hirst, D., Campbell, F. & McGuigan, J., Jan 2004, In : British Journal of Surgery. 91, p. 1217-1217 1 p.

Research output: Contribution to journalArticle

H+/amino acid transporter 1 (PAT1) is the imino acid carrier: An intestinal nutrient/drug transporter in human and rat.

Campbell, F., Nov 2004, In : Gastroenterology. 127(5), 5, p. 1410-1422 13 p.

Research output: Contribution to journalArticle

98 Citations (Scopus)

Modulation of N-methyl-N-nitrosourea-induced crypt restricted metallothionein immunopositivity in mouse colon by a non-genotoxic diet-related chemical.

Donnelly, E., Phillips, D. H., Williams, E. D., Bardwell, H., Thomas, G. A., Hoper, M., Crowe, P., McCluggage, W. G., Stevenson, M., Hewer, A., Osborne, M. R. & Campbell, F., May 2004, In : Carcinogenesis. 25(5), 5, p. 847-855 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2002

Ischemic preconditioning before lower limb ischemia-reperfusion protects against acute lung injury

Harkin, D., Barros D'Sa, A., McCallion, K., Hoper, M. & Campbell, F., Jun 2002, In : Journal of Vascular Surgery. 35, 6, p. 1264-1273 10 p.

Research output: Contribution to journalArticle

96 Citations (Scopus)
2001

Bactericidal/permeability-increasing protein attenuates systemic inflammation and acute lung injury in porcine lower limb ischemia-reperfusion injury.

Harkin, D., Barros D'Sa, A., McCallion, K., Hoper, M., Halliday, M. I. & Campbell, F., 2001, In : Annals of Surgery. 234(2), 2, p. 233-244 12 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Curcumin modifies Apc(min) apoptosis resistance and inhibits 2-amino 1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) induced tumour formation in Apc(min) mice.

Collett, G., Robson, C. N., Mathers, J. C. & Campbell, F., 2001, In : Carcinogenesis. 22(5), p. 821-825 5 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)

Phenol sulphotransferase SULT1A1*1 genotype is associated with reduced risk of colorectal cancer.

Campbell, F., 2001, In : Pharmacogenetics. 11(8), 8, p. 679-685 7 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)

Recombinant bactericidal/permeability-increasing protein attenuates the systemic inflammatory response syndrome in lower limb ischemia-reperfusion injury.

Harkin, D., Barros D'Sa, A., Yassin, M. M., Hoper, M., Halliday, M. I., Parks, T. G. & Campbell, F., Apr 2001, In : Journal of Vascular Surgery. 33(4), 4, p. 840-846 7 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)