• Room 0G.107 - Biological Sciences

    United Kingdom

Accepting PhD Students

PhD projects

I am open to PhD applications from individuals holding or expecting to hold at least a 2.1 degree (or equivalent) in the fields of computer science, bioinformatics, biochemistry, microbiology or marine biology. A strategy for obtaining funding for a PhD is required. Applicants should be interested in computational biology approaches, multi-omics data integration and systems and network biology. Individuals interested in working with Prof Hardiman are welcome to contact him to discuss ideas and/or possible collaborations.

1994 …2020

Research output per year

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Personal profile

Research Interests

I work in the field of systems biology the objective of which is the study of biological systems, including genes, RNAs, proteins, metabolites and cells in a focused manner, and organs, organisms and populations in a broader context. Areas of research focus include; 

  • Studying the effects of man-made contaminants (e.g. microplastics, persistent organic pollutants, xenobiotics) on marine and human health
  • Studying prostate cancer in the context of racial differences and nutritional deficiency
  • Examining the impacts of long term space travel – specifically the effects of nutrition, torpor, space radiation and microgravity on hepatic and intestinal biology
  • Developing a rat model of opioid abuse to better understand the biological basis for substance abuse disorders and advance development of preventive strategies and more efficacious treatments
  • Developing a robust toolkit for better integration of Omics data sets into genotype-phenotype predictions.

I maintain active research collaborations with groups in the USA (University of California, Medical University of South Carolina, Wake Forest School of Medicine), (Université de Camerino & Università Politecnica delle Marche (Italy), National University of Ireland Galway (Ireland) & University of Aberdeen (Scotland).

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Research Output

NASA GeneLab Platform Utilized for Biological Response to Space Radiation in Animal Models

McDonald, J. T., Stainforth, R., Miller, J., Cahill, T., da Silveira, W. A., Rathi, K. S., Hardiman, G., Taylor, D., Costes, S. V., Chauhan, V., Meller, R. & Beheshti, A., 07 Feb 2020, In : Cancers. 12, 2, 24 p., 381.

Research output: Contribution to journalArticle

Open Access
File
  • 9 Downloads (Pure)

    A de novo transcriptome assembly approach elucidates the dynamics of ovarian maturation in the swordfish (Xiphias gladius)

    Gioacchini, G., Marisaldi, L., Basili, D., Candelma, M., Pignalosa, P., Aiese Cigliano, R., Sanseverino, W., Hardiman, G. & Carnevali, O., 01 Dec 2019, In : Scientific Reports. 9, 1, 7375.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 1 Citation (Scopus)
    82 Downloads (Pure)

    A high prevalence of biallelic RPE65 mutations in Costa Rican children with Leber congenital amaurosis and early-onset retinal dystrophy

    Glen, W. B., Peterseim, M. M. W., Badilla, R., Znoyko, I., Bourg, A., Wilson, R., Hardiman, G., Wolff, D. & Martinez, J., 14 Mar 2019, In : Ophthalmic genetics. 40, 2, p. 110-117 8 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 4 Downloads (Pure)

    A Human Skin Model Recapitulates Systemic Sclerosis Dermal Fibrosis and Identifies COL22A1 as a TGFβ Early Response Gene that Mediates Fibroblast to Myofibroblast Transition

    Watanabe, T., Baker Frost, D., Mlakar, L., Heywood, J., da Silveira, W. A., Hardiman, G. & Feghali-Bostwick, C., 22 Jan 2019, In : Genes. 10, 2

    Research output: Contribution to journalArticle

    Open Access
    File
  • 2 Citations (Scopus)
    87 Downloads (Pure)

    GAIL: An interactive webserver for inference and dynamic visualization of gene-gene associations based on gene ontology guided mining of biomedical literature

    Couch, D., Yu, Z., Nam, J. H., Allen, C., Ramos, P. S., da Silveira, W. A., Hunt, K. J., Hazard, E. S., Hardiman, G., Lawson, A. & Chung, D., 01 Jul 2019, In : PLoS ONE. 14, 7, 19 p., e0219195.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 59 Downloads (Pure)