Projects per year
I work in the field of systems biology the objective of which is the study of biological systems, including genes, RNAs, proteins, metabolites and cells in a focused manner, and organs, organisms and populations in a broader context. Areas of research focus include;
- Studying the effects of man-made contaminants (e.g. microplastics, persistent organic pollutants, xenobiotics) on marine and human health
- Studying prostate cancer in the context of racial differences and nutritional deficiency
- Examining the impacts of long term space travel – specifically the effects of nutrition, torpor, space radiation and microgravity on hepatic and intestinal biology
- Developing a rat model of opioid abuse to better understand the biological basis for substance abuse disorders and advance development of preventive strategies and more efficacious treatments
- Developing a robust toolkit for better integration of Omics data sets into genotype-phenotype predictions.
I maintain active research collaborations with groups in the USA (University of California, Medical University of South Carolina, Wake Forest School of Medicine), (Université de Camerino & Università Politecnica delle Marche (Italy), National University of Ireland Galway (Ireland) & University of Aberdeen (Scotland).
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Morgan, R., Keeley, D., Hazard, E. S., Allott, E. H., Wolf, B., Savage, S. J., Hughes Halbert, C., Gattoni-Celli, S. & Hardiman, G., 20 Apr 2022, In: Biology. 11, 5, e625.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile11 Downloads (Pure)
Integrated Genomic and Bioinformatics Approaches to Identify Molecular Links between Endocrine Disruptors and Adverse OutcomesVerga, J. U., Huff, M., Owens, D., Wolf, B. J. & Hardiman, G., 05 Jan 2022, In: International Journal of Environmental Research and Public Health. 19, 1, e574.
Research output: Contribution to journal › Review article › peer-reviewOpen AccessFile74 Downloads (Pure)
miRNA and lncRNA Expression Networks Modulate Cell Cycle and DNA Repair Inhibition in Senescent Prostate Cellsda Silveira, W. A., Renaud, L., Hazard, E. S. & Hardiman, G., 24 Jan 2022, (Early online date) In: Genes. 13, 2, 17 p., e208.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile38 Downloads (Pure)
Antifibrotic factor KLF4 is repressed by the miR-10/TFAP2A/TBX5 axis in dermal fibroblasts: insights from twins discordant for systemic sclerosisMalaab, M., Renaud, L., Takamura, N., Zimmerman, K. D., da Silveira, W. A., Ramos, P. S., Haddad, S., Peters-Golden, M., Penke, L. R., Wolf, B., Hardiman, G., Langefeld, C. D., Medsger, T. A. & Feghali-Bostwick, C. A., 08 Nov 2021, (Early online date) In: Annals of the rheumatic diseases.
Research output: Contribution to journal › Article › peer-review
A Systems Approach to Interrogate Gene Expression Patterns in African American Men Presenting with Clinically Localized Prostate CancerHardiman, G., Savage, S. J., Hazard, E. S., da Silveira, W. A., Morgan, R., Harris, A., Jefferson, M. S., Wilson, R. C., Caulder, S., Ambrose, L., Frey, L., Wolf, B., Gattoni-Celli, S. & Hughes Halbert, C., 14 Oct 2021, In: Cancers. 13, 20, 5143.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile75 Downloads (Pure)
The Joint Conference of ISEH 2020 (The 5th International Symposium on Environment and Health), ICEPH 2020 (The 6th International Conference on Environmental Pollution and Health) & G16 2020 (The 7th International Conference on Research Frontiers on Chalcogen Cycle Science and Technology)
Kieran O'Driscoll (Member of the scientific committee) & Gary Hardiman (Member of scientific committee)02 Aug 2020 → 09 Aug 2020
Activity: Participating in or organising an event types › Participation in conference
Press / Media
Media Coverage of 'hibernating zebrafish' and radiation exposure risk for space travel research article
25/05/2021 → 29/05/2021
2 items of Media coverage
Press/Media: Public Engagement Activities