1988 …2018
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Personal profile

Interests

Evaluation of antihypertensive and metabolic effects of drug therapies to treat hypertension.

Research Statement

My research is clinically orientated and addresses the problem of arterial blood vessel disease. Early arterial blood vessel disease is asymptomatic but precedes and predicts further disease development and future clinical complications such as heart attack and stroke. To detect and monitor early disease requires the use of a sensitive diagnostic assessment tool.

Ultrasound is used globally to diagnose, assess severity and monitor disease progression in arterial blood vessels. Detection of vascular disease is inferred from analysis of the recorded blood flow patterns using software embedded in commercial ultrasound systems. We have developed novel software algorithms to analyse blood flow signals that are more sensitive than existing commercially available applications in detecting early blood vessel damage and monitoring the effects of drug interventions. As our analysis technique is applicable to the standard output from all commercially available ultrasound systems, we believe comprehensive roll-out of our novel invention is feasible in the clinical arena. I was awarded a UK Medical Futures Award for this work in June 2007. The incremental developments in the technique have led to collaborative work with colleagues in the USA.

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Research Output 1988 2018

Smooth Muscle Myocytes
Fibroblasts
Lung
Vasodilator Agents
Pulmonary Hypertension

Statin therapy does not significantly alter microvascular function in uncomplicated hypertension

Bleakley, C., McCann, A., McClenaghan, V., Hamilton, P., Millar, A., Plumb, R., Harbinson, M. & McVeigh, G., 01 Jun 2017, In : Journal for Vascular Ultrasound. 41, p. 66-70

Research output: Contribution to journalArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Brachial Artery
Hypertension
Confidence Intervals
Blood Vessels
6 Citations (Scopus)

A Reappraisal of the Safety and Cost-Effectiveness of Statin Therapy in Primary Prevention

Bleakley, C., Pumb, R., Harbinson, M. & McVeigh, G. E., Dec 2015, In : The Canadian journal of cardiology. 31, 12, p. 1411-4 4 p.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Primary Prevention
Cost-Benefit Analysis
Secondary Prevention
Safety
23 Citations (Scopus)

Endothelial Function in Hypertension: Victim or Culprit?

Bleakley, C., Hamilton, P. K., Pumb, R., Harbinson, M. & McVeigh, G. E., Aug 2015, In : Journal of clinical hypertension (Greenwich, Conn.). 17, 8, p. 651-4 4 p.

Research output: Contribution to journalArticle

Blood Vessels
Hypertension
Endothelium
Nitric Oxide
Nitric Oxide Synthase Type III

Ultrasound entropy may be a new non-invasive marker of pre-clinical vascular damage in young hypertensive patients

Bleakley, C., McCann, A., McClenaghan, V., Hamilton, P., Millar, A., Plumb, R., Harbinson, M. & McVeigh, G., 2015, In : Cardiovascular ultrasound. 13, p. 12-20

Research output: Contribution to journalArticle

Prizes

Executive Committee Member

Gary McVeigh (Recipient), 2007

Prize: Election to learned society

Committee Membership

Holder of a Wellcome Travel Fellowship

Gary McVeigh (Recipient), 1988

Prize: Fellowship awarded competitively

Activities 1995 2013

Certificate in Prescribing Course (NIMDTA)

Gary McVeigh (Invited speaker)
07 Feb 2013

Activity: Participating in or organising an event typesParticipation in workshop, seminar, course

Non-Invasive Assessment of the Vascular System

Gary McVeigh (Invited speaker)
31 Jan 2013

Activity: Participating in or organising an event typesParticipation in workshop, seminar, course

Northern Ireland Medical and Dental Training Association

Gary McVeigh (Participant)
13 Jan 2012

Activity: Participating in or organising an event typesParticipation in workshop, seminar, course

Certificate in Prescribing Course (NIMDTA)

Gary McVeigh (Speaker)
2012

Activity: Participating in or organising an event typesParticipation in workshop, seminar, course

Cardiology Update

Gary McVeigh (Participant)
20 Apr 2012

Activity: Participating in or organising an event typesParticipation in workshop, seminar, course