Research output per year
Research output per year
- 1 - 50 out of 51 results
Search results
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2024
A multi-omics-based evaluation of the effects of valaciclovir on the sputum proteome, microbiome and metabolome of COPD
Delaney , R., Einarsson, G., Cameron, S., Kidney, J. C., Tunney, M., Taggart, C. & Linden, D., 03 Nov 2024, In: Thorax. 79, Suppl 2, p. A49-A50 2 p.Research output: Contribution to journal › Meeting abstract › peer-review
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Reversal of levofloxacin resistance in cystic fibrosis-associated Pseudomonas aeruginosa through dual inhibition of efflux pumps and DNA topoisomerases
Sloan, C. M., Sherrard, L. J., Einarsson, G. G., Tunney, M. M. & Downey, D. G., 07 Jun 2024, In: Journal of Cystic Fibrosis. 23, Supplement 1, p. S41 1 p., EPS3.04.Research output: Contribution to journal › Meeting abstract › peer-review
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WS09.04 Airway microbial dynamics and inflammation: insights from the Mountain West CF Consortium’s research findings
Einarsson, G. G., Carson, J. P., Elborn, J. S., Adler, F. R., Tunney, M. M. & Liou, T. G., 07 Jun 2024, In: Journal of Cystic Fibrosis. 23, Supplement 1, p. S17 1 p.Research output: Contribution to journal › Meeting abstract › peer-review
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2023
A mechanistic analysis of the effect of valaciclovir for EBV suppression on airway inflammation and microbiome in COPD
Linden, D., Guo-Parke, H., Einarsson, G., Carson, S., Lee, A., Fairley, D., Singh, D., Tunney, M., Mcauley, D., Taggart, C. & Kidney, J., 19 May 2023, In: ERJ Open Research. 9, Suppl. 10, 1 p., 59.Research output: Contribution to journal › Meeting abstract › peer-review
Open Access -
Changes in biofilm-tolerance of Pseudomonas aeruginosa to tobramycin following treatment with tobramycin inhalation powder (TIP)
McCleave, R., Einarsson, G., Loebinger, M., Chalmers, J., Elborn, S. J., Haworth, C., Tunney, M. & Sherrard, L., 09 Jun 2023, In: Journal of Cystic Fibrosis. 22, p. S61-S62 2 p., EPS9.04 .Research output: Contribution to journal › Meeting abstract › peer-review
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Characterisation of the CF sputum proteome reveals that innate host defence proteins are depleted in frequent exacerbators
Houston, C., Alkhatib, A., Einarsson, G., Tunney, M., Taggart, C. & Downey, D., 09 Sept 2023, In: European Respiratory Journal. 62, suppl 67, OA1536.Research output: Contribution to journal › Meeting abstract › peer-review
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Development of levofloxacin resistance in clinical Pseudomonas aeruginosa isolates from people with cystic fibrosis in an in vitro variable exposure model
Sloan, C. M., Sherrard, L. J., Einarsson, G. G., Tunney, M. M. & Downey, D. G., 01 Jun 2023, In: Journal of Cystic Fibrosis. 22 , Supplement 2, p. S62 1 p., EPS9.06.Research output: Contribution to journal › Meeting abstract › peer-review
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In vitro evolution of levofloxacin resistance in lineages of clinical Pseudomonas aeruginosa isolates cultured at different stages of infection from people with cystic fibrosis
Sloan, C. M., Sherrard, L. J., Einarsson, G. G., Hoffman, L. R., Tunney, M. M. & Downey, D. G., 01 Jun 2023, In: Journal of Cystic Fibrosis. 22, Supplement 2, p. S135 1 p., P228.Research output: Contribution to journal › Meeting abstract › peer-review
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Optimisation of inhaled antibiotic prescribing for Pseudomonas aeruginosa infections in people with cystic fibrosis: further insights from principal investigators of the ECFS Clinical Trials Network
Sloan, C. M., Sherrard, L. J., Einarsson, G. G., Dupont, L. J., van Koningsbruggen-Rietschel, S., Simmonds, N. J. & Downey, D. G., 09 Jun 2023, In: Journal of Cystic Fibrosis. 22 , Supplement 2, p. S143 1 p., P253.Research output: Contribution to journal › Meeting abstract › peer-review
Open Access -
2022
Antimicrobial prescribing in people with cystic fibrosis: exploring inhaled antibiotic use for Pseudomonas aeruginosa infections across the ECFS-CTN
Sloan, C., Sherrard, L., Einarsson, G., Dupont, L. J., Simmonds, N., van Koningsbruggen-Rietschel, S. & Downey, D., 01 Jun 2022, In: Journal of Cystic Fibrosis. 21, Supplement 1, p. S107 1 p., P150.Research output: Contribution to journal › Meeting abstract › peer-review
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Induced levofloxacin resistance persists in evolved lineages of Pseudomonas aeruginosa isolates from people with cystic fibrosis after exposure to other inhaled antibiotics
Sloan, C. M., Sherrard, L. J., Einarsson, G. G., Tunney, M. M. & Downey, D. G., 01 Jun 2022, In: Journal of Cystic Fibrosis. 21, Supplement 1, p. S50 1 p., ePS3.05.Research output: Contribution to journal › Meeting abstract › peer-review
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Inhaled powder tobramycin (TIP): cyclical versus continuous treatment: iBEST Study
Alkhatib, A., Einarsson, G. G., Lee, A. J., O’Neill, K., Brown, V., Gilpin, D. F., Angyalosi, G., Malaterre, V., Loebinger, M. R., Chalmers, J. D., Blasi, F., Haworth, C. S., Elborn, J. S. & Tunney, M. M., 10 Jun 2022, In: Journal of Cystic Fibrosis. 21, Supplement 1, p. S51 1 p., ePS3.08.Research output: Contribution to journal › Meeting abstract › peer-review
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Pseudomonas aeruginosa infection during long-term suppression treatment with tobramycin inhalation powder (TIP)
McCleave, R., Li, Z., Einarsson, G., Loebinger, M., Chalmers, J., Elborn, S., Haworth, C., McKenna, J., Fairley, D., Allen, D., Tunney, M. & Sherrard, L., 01 Jun 2022, In: Journal of Cystic Fibrosis. 21, Supplement 1, p. S99-S100 P126.Research output: Contribution to journal › Meeting abstract › peer-review
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Valaciclovir for Epstein-Barr virus suppression in chronic obstructive pulmonary disease: a randomised controlled trial (EViSCO)
Linden, D., Guo-Parke, H., McKelvey, M., Einarsson, G., Lee, A., Fairley, D., Brown, V., Logan, D., Campbell, C., Singh, D., Tunney, M., McAuley, D., Taggart, C. & Kidney, J., 04 Sept 2022, In: European Respiratory Journal. 60, Suppl 66, 856.Research output: Contribution to journal › Meeting abstract › peer-review
Open Access -
2021
Changes in sputum bacterial density in people with bronchiectasis: BRONCH UK study data
Alfahl, Z., Einarsson, G. G., O'Neill, K., Gilpin, D. F., Elborn, J. S., Hill, A., Ferguson, K., Loebinger , M. R., Carroll, M., Gatheral, T., de Soyza, A., Johnson, C., Chalmers, J. D., Hurst, J., Brown, J., Bradley, J. M. & Tunney, M. M., 25 Nov 2021, In: European Respiratory Journal. 58, suppl 65Research output: Contribution to journal › Meeting abstract › peer-review
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Evolution of levofloxacin resistance and phenotypic characterisation of Pseudomonas aeruginosa clinical isolates from people with cystic fibrosis
Sloan, C. M., Sherrard, L. J., Einarsson, G. G., Tunney, M. M. & Downey, D. G., 01 Jun 2021, In: Journal of Cystic Fibrosis. 20, Supplement 1, p. S84-S85 P149.Research output: Contribution to journal › Meeting abstract › peer-review
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P147: Changes in Pseudomonas aeruginosa phenotypes following the development of tobramycin resistance
McCleave, R. P., Li, Z., Einarsson, G. G., Tunney, M. M., Loebinger, M. R., Chalmers, J. D., Elborn, S. J., Haworth, C. S. & Sherrard, L. J., 01 Jun 2021, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 20, Supplement 1, p. S84 1 p., P147.Research output: Contribution to journal › Meeting abstract › peer-review
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Poster Abstract: EPS3.01 Is variation in Pseudomonas aeruginosa (Pa) surface-enhanced Raman spectroscopy (SERS) spectra related to phenotype?
Allen, D., Einarsson, G. G., Elborn, J. S., Bell, S. & Tunney, M. M., 11 Jun 2021, In: Journal of Cystic Fibrosis. 20, S35, p. S35 1 p.Research output: Contribution to journal › Meeting abstract › peer-review
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Sputum proteomics identifies mechanisms of disease severity and treatment response in bronchiectasis
Keir, H. R., Shoemark, A., Crichton, M. L., Dicker, A., Pollock, J., Giam, A., Cassidy, A., Fong, C., Finch, S., Furrie, E., Suarez-Cuartin, G., Fardon, T. C., Einarsson, G., Elborn, J. S., Aliberti, S., Sibila, O., Huang, J. & Chalmers, J. D., 21 Jan 2021, In: Thorax. 76, Suppl 1, p. A3 1 p., T6.Research output: Contribution to journal › Meeting abstract › peer-review
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2020
Longitudinal assessment of sputum total bacterial, Pseudomonas aeruginosa and Haemophilus influenzae load in people with bronchiectasis when clinically stable and at the start and end of treatment of an exacerbation: Data from the BRONCH UK Study.
Alfahl, Z., Einarsson, G., Elborn, S., O'Neill, K., Fergunson, K., Hill, A., Loebinger , M. R., Carroll, M., Gatheral , T., De Soyza , A., Chalmers , J., Johnson , C., Hurst, J., Brown , J., Bradley, J. & Tunney, M., Dec 2020, In: European Respiratory & Pulmonary Diseases. 6, Supplement 2, p. 2-3 2 p.Research output: Contribution to journal › Meeting abstract › peer-review
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P081 The airway microbiome dynamics: relationships with disease and health
Einarsson, G., Lord, R., Lee, A., Smith, J., Elborn, S., Jones, A. & Tunney, M., 01 Jun 2020, In: Journal of Cystic Fibrosis. 19, S2, p. S78 P081.Research output: Contribution to journal › Meeting abstract › peer-review
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P085 The effect of gastro-oesophageal reflux on the respiratory tract microbiome
Lord, R., Einarsson, G., Lee, A., Elborn, S., Smith, J., Tunney, M. & Jones, A., 01 Jun 2020, In: Journal of Cystic Fibrosis. 19, S2, p. S79 1 p., P085.Research output: Contribution to journal › Meeting abstract › peer-review
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2019
322 longitudinal analysis of the lower airway microbiota in pwcf during periods of clinical stability
Einarsson, G., Sherrard, L., Johnston, E., O'Neill, K., McIlreavey, L., McGrath, S., Gilpin, D., Hatch, J., Zorn, B., Murray, M., Lavelle, G., McElvaney, G., Wolfgang, M. C., Boucher, R. C., Muhlebach, M. S., Elborn, S. & Tunney, M., Oct 2019, In: Pediatric Pulmonology. 54, S2, p. 276Research output: Contribution to journal › Meeting abstract › peer-review
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356 association between multi-drug resistant pseusdomonas aeruginosa and viable bacterial community profiles in sputum
Sherrard, L., Einarsson, G., Allen, D., Johnston, E., O'Neill, K., McIlreavey, L., McGrath, S., Gilpin, D., Hatch, J. E., Zorn, B., Murray, M., Lavelle, G., McElvaney, G., Wolfgang, M. C., Boucher, R. C., Muhlebach, M. S., Elborn, S. & Tunney, M., Oct 2019, In: Pediatric Pulmonology. 54, S2, p. 289Research output: Contribution to journal › Meeting abstract › peer-review
16 Citations (Scopus) -
P140 Microbial community composition in cystic fibrosis patients during treatment for pulmonary exacerbation
Einarsson, G., Sherrard, L., Zorn, B., Hatch, J., McGettigan, C., Bradbury, I., Campbell, C., Johnston, E., O'Neill, K., McIlreavey, L., McGrath, S., Gilpin, D., Murray, M., Lavelle, G., McElvaney, G., Wolfgang, M. C., Boucher, R. C., Muhlebach, M. S., Elborn, S. & Tunney, M., Jun 2019, In: Journal of Cystic Fibrosis. 18, Supplement 1, p. S97Research output: Contribution to journal › Meeting abstract › peer-review
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P179 Detection of multi-drug resistant (MDR) Pseudomonas aeruginosa (PA) in people with cystic fibrosis
Sherrard, L., Allen, D., Barron, M., Einarsson, G., Johnston, E., O'Neill, K., McIlreavey, L., McGrath, S., Gilpin, D., Downey, D., Reid, A., McElvaney, N., Boucher, R. C., Muhlebach, M. S., Elborn, S. & Tunney, M., Jun 2019, In: Journal of Cystic Fibrosis. 18, S1, p. S108Research output: Contribution to journal › Meeting abstract › peer-review
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P242 Does gastro-oesophageal reflux influence the respiratory tract microbiome in cystic fibrosis patients?
Lord, R., Einarsson, G., Lee, A., Bianco, B., Whorwell, P., Elborn, J., Tunney, M. & Jones, A., 12 Nov 2019, In: Thorax. 74, Suppl 2, A221.Research output: Contribution to journal › Meeting abstract › peer-review
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P250 The microbial landscape of the upper and lower respiratory tract in PWCF and healthy individuals
Einarsson, G., Lord, R., Lee, A., Smith, J., Elborn, J., Jones, M. & Tunney, M., 12 Nov 2019, In: Thorax. 74, Suppl 2, A226.Research output: Contribution to journal › Meeting abstract › peer-review
Open Access -
Poster abstract: Changes in the lung microbiota in response to IV therapy for pulmonary exacerbations and relation to clinical outcomes
Addy, C., Einarsson, G. G., Lee, A. L., Bradley, J. M., Elborn, J. S., Downey, D. G. & Tunney, M. M., Jun 2019, In: Journal of Cystic Fibrosis. 18, Supplement 1, p. S98 P144.Research output: Contribution to journal › Meeting abstract › peer-review
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2018
414 Baseline microbial community composition in clinically stable CF patients compared to those experiencing episodes of pulmonary exacerbation.
Einarsson, G., Sherrard, L., Zorn, B., Hatch, J. E., Bradbury, I., Campbell, C., Johnston, E., O'Neill, K., McIlreavey, L., McGrath, S., Gilpin, D., Murray, M., Lavelle, G., McElvaney, G., Boucher, R. C., Muhlebach, M. S., Elborn, S. & Tunney, M., Sept 2018, In: Pediatric Pulmonology. 53, S2, p. 305Research output: Contribution to journal › Meeting abstract › peer-review
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415 comparison of microbial community composition in cf patients with and without cf-related diabetes
Einarsson, G., Sherrard, L., Zorn, B., Hatch, J., Bradbury, I., Campbell, C., Gilpin, D., Murray, M., Lavelle, G., McElvaney, G., Boucher, R. C., Muhlebach, M. S., Elborn, S. & Tunney, M., Sept 2018, In: Pediatric Pulmonology. 53, S2, p. 305Research output: Contribution to journal › Meeting abstract › peer-review
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A cross-sectional analysis of cough swabs from non-expectorating CF patients and healthy control participants
Einarsson, G. G., Sherrard, L. J., Johnston, E., O'Neill, K., McIlreavey, L., McGrath, S. J., Gilpin, D. F., Murray, M., Lavelle, G., McElvaney, G., Boucher, R. C., Muhlebach, M., Elborn, J. S. & Tunney, M. M., 03 Jun 2018, In: Journal of Cystic Fibrosis. 17, Supplement 3, p. S74-S75 1 p., P055.Research output: Contribution to journal › Meeting abstract › peer-review
Open Access -
Determining the relationship between absolute quantification and relative abundance as determined by next generation sequencing
McGettigan, C., Johnston, E., Elborn, J. S., Lee, A. J., Sherrard, L., Damian, D., Einarsson, G. G., Spence, C., Muhlebach, M., Boucher, R., Mcelvaney, G., Murray, M., Lavelle, G., Tunney, M. M. & Gilpin, D. F., 01 Jun 2018, In: Journal of Cystic Fibrosis. 17, Suppl 3, p. S44 1 p., EPS4.05.Research output: Contribution to journal › Meeting abstract › peer-review
Open Access -
Longitudinal analysis of the lower airway microbiota in cystic fibrosis patients during clinical stability compared to those experiencing episodes of pulmonary exacerbation
Einarsson, G. G., Sherrard, L. J., Johnston, E., O'Neill, K., McIlreavey, L., McGrath, S. J., Lavelle, G., Gilpin, D. F., McElvaney, G., Boucher, R., Murray, M., Muhlebach, M., Elborn, J. S. & Tunney, M. M., Jun 2018, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 17, 3 (Supplement), p. S79 1 p., P070.Research output: Contribution to journal › Meeting abstract › peer-review
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P053 Use of extended-quantitative culture does not predict an imminent pulmonary exacerbation
Sherrard, L., Einarsson, G., Johnston, E., O'neill, K., Mcilreavey, L., Mcgrath, S., Gilpin, D., Murray, M., Lavelle, G., Mcelvaney, G., Boucher, R., Muchlebach, M., Elborn, J. S. & Tunney, M., 01 Jun 2018, In: Journal of Cystic Fibrosis. 17, 1 p., S74.Research output: Contribution to journal › Meeting abstract › peer-review
Open Access -
P053 Use of extended-quantitative culture does not predict an imminent pulmonary exacerbation (PEx).
Sherrard, L., Einarsson, G., Johnston, E., O'Neill, K., McIlreavey, L., McGrath, S., Gilpin, D., Murray, M. A., Lavelle, G. M., McElvaney, N., Boucher, R. C., Muhlebach, M. S., Elborn, J. & Tunney, M., Jun 2018, In: Journal of Cystic Fibrosis.Research output: Contribution to journal › Meeting abstract › peer-review
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The Impact of Azithromycin on the Post Lung Transplant Microbiome
Verleden, S., Spence, C., Einarsson, G., Johnston, E., Lee, A., Vanaudenaerde, B., Elborn, J., Vos, R. & Tunney, M., Apr 2018, In: Journal of Heart and Lung Transplantation. 37, 4 (Supplement), p. S455 1 p.Research output: Contribution to journal › Meeting abstract › peer-review
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Use of qPCR to analyse changes in total bacterial and Pseudomonas aeruginosa load in cystic fibrosis patients when clinically stable and during exacerbations
MCGettigan, C., Spence, C., Lee, A. J., Sherrard, L., Johnston, E., Einarsson, G. G., Elborn, J. S., Downey, D., Muhlebach, M., Boucher, R., MCElvaney, G., Michelle, M., Lavelle, G., Tunney, M. M. & Gilpin, D. F., 01 Jun 2018, In: Journal of Cystic Fibrosis. 17, Supplement 3, p. S80 P073.Research output: Contribution to journal › Meeting abstract › peer-review
Open Access -
2017
Assessment of putative virulence determinants in Prevotella spp. from the lower airways of patients with cystic fibrosis
Einarsson, G. G., Sherrard, L., Falkowski, N., Erb-Downward , J., Elborn, J. R., Huffnagle , G. & Tunney, M. M., Sept 2017, In: Pediatric Pulmonology. 52, S47, p. 379 1 p., 431.Research output: Contribution to journal › Meeting abstract › peer-review
Open Access -
WS03.1 Longitudinal airway microbiota profiling in cystic fibrosis patients enrolled in the CFMATTERS clinical trial
Einarsson, G., Flanagan, E., Lee, A., Elborn, J. S., Tunny, M. & Plant , B. J., 01 Jun 2017, In: Journal of Cystic Fibrosis. 16, supplement 1 , S4.Research output: Contribution to journal › Meeting abstract › peer-review
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WS03.6: Estimation of total bacterial load in explanted cystic fibrosis (CF) lungs via qPCR
Spence, C. D., Einarsson, G., Lee, A. J., McGettigan, C., Johnston, E., Verleden, S., Vanaudenaerde, B. M., McDonough, J., Lammertyn, E. J., Dupont, L., Elborn, J. S., Gilpin, D. F. & Tunney, M., 01 Jun 2017, In: Journal of Cystic Fibrosis. 16, Supplement 1, p. S6 1 p.Research output: Contribution to journal › Meeting abstract › peer-review
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2016
Altered lung microbiota profiles are associated with disease severity, exacerbation frequency and neutrophilic inflammation in bronchiectasis
Dicker, A. J., Fong, C., Crichton, M., Cassidy, A., Suarez-Cuartin, G., Sibila, O., Einarsson, G. G., Ibrahim, W., Elborn, J., Palmer, C. N. A., Fardon, T., Marshall, S. & Chalmers, J. D., 16 May 2016, In: American Journal of Respiratory and Critical Care Medicine. 193, 1 p., A2879.Research output: Contribution to journal › Meeting abstract › peer-review
Open Access -
Mannose binding lectin deficient haplotypes are associated with fewer exacerbations and a more diverse microbiome in chronic obstructive pulmonary disease
Dicker, A. J., Crichton, M., Cassidy, A., Brady, G., Hapca, A., Einarsson, G. G., Elborn, J., Schembri, S., Marshall, S., Palmer, C. N. A. & Chalmers, J. D., 15 May 2016, In: American Journal of Respiratory and Critical Care Medicine. 193, 1 p., A1075.Research output: Contribution to journal › Meeting abstract › peer-review
Open Access -
2015
94 Isolation and characterisation of bacteriophage infecting Prevotella spp. recovered from the cystic fibrosis (CF) airways
Mooney, D., Tunney, M. M., McGrath, S., McIlreavey, L., Einarsson, G., Pattison, S., Johnston, E. & Elborn, J. S., 05 Jun 2015, In: Journal of Cystic Fibrosis. 14, Supplement 1, p. S81 1 p.Research output: Contribution to journal › Meeting abstract › peer-review
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Microbial community composition in explanted cystic fibrosis (CF) lungs
Tunney, M. M., McLean, D., Einarsson, G., Elborn, J., Lammertyn, E., Bosch, B., Vermeulen, F., Verleden, S., De Boeck, K., Dupont, L. & Vanaudenaerde, B., Oct 2015, In: Pediatric Pulmonology. 50, S41, 304.Research output: Contribution to journal › Meeting abstract › peer-review
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The effect of ivacaftor treatment on airway microbial community dynamics in patients with G551D (the “cELTIC” mutation)
Einarsson, G. G., Ronan, N. J., McIlreavey, L., O'Callaghan, G., Murphy, D. M., Tunney, M. M., Elborn, J. & Plant, B. J., 04 Sept 2015, In: Pediatric Pulmonology. 50, p. 302-303 2 p.Research output: Contribution to journal › Meeting abstract › peer-review
35 Citations (Scopus) -
2013
Airway bacterial community structure and correlation during health and disease
Einarsson, G. G., Tunney, M., Klem, E. R., Fodor, A. A., Wolfgang, M. C. & Elborn, J. S., 01 Jun 2013, In: Journal of Cystic Fibrosis. 12, Supplement 1, p. S17 WS8.5.Research output: Contribution to journal › Meeting abstract › peer-review
Open Access -
Culture and culture independant identification of bacterial communities in the cystic fibrosis respiratory tract
Einarsson, G. G., McCaughan, J., Fodor, A. A., Wolfgang, M. C., Tunney, M. M. & Elborn, J. S., 14 Nov 2013, In: Thorax. 68, Suppl 3, 1 p., A121.Research output: Contribution to journal › Meeting abstract › peer-review
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2012
104 Culture dependent and independent analysis of microbial community composition in the lungs of patients with cystic fibrosis and non-cystic fibrosis bronchiectasis
Einarsson, G. G., Klem, E., Wei, L., Wolfgang, M. C., Tunney, M. & Elborn, J. S., 06 Jun 2012, In: Journal of Cystic Fibrosis. 11, Supplement 1 , p. S83Research output: Contribution to journal › Meeting abstract › peer-review
Open Access -
2011
The culture microbiome in the lungs of patients with COPD
Einarsson, G. G., Comer, D., Tunney, M. M. & Elborn, J. S., 02 Dec 2011, In: Thorax. 66, Suppl 4, p. A48-A49 2 p., S104.Research output: Contribution to journal › Meeting abstract › peer-review