Projects per year
Personal profile
Research Interests
I am Lead of the Cancer Epidemiology Research Group at the Centre for Public Health at Queen's University Belfast. I am Deputy Director of the Northern Ireland Cancer Registry.
My research mostly focuses on the epidemiology and early detection of gastrointestinal cancers and conditions, including pre-malignant conditions. I have particular interests in:
- Barrett's oesophagus and oesophageal adenocarcinoma (major ongoing studies include: PI of the Northern Ireland Barrett's oesophagus register; OCCAMS consortium sub-study investigator)
- Colorectal polyps and colorectal cancer (major ongoing studies include: NI Biobank Epi700 cohort; NI Bowel Cancer Screening pathology data analysis; Early-onset colorectal cancer studies).
- Modifiable risk factors, such as smoking, alcohol and nutrition, in cancer risk and progression
- Gastrointestinal pathology diagnosis trends and concordance (member of the International Barrett's Pathology Working Group)
I have expertise in molecular epidemiology (incuding molecular pathology epidemiology) studies, statistical analysis of population-based disease registers and real world evidence, and systematic reviews of lifestyle factors and biomarkers in cancer risk and progression.
I place considerable emphasis on interdisciplinary research, and am affiliated to the Patrick G. Johnston Centre for Cancer Research at Queen's University Belfast. I have previously spent time conducting research at Vanderbilt University, Nashville, TN, USA, Ulster University, and at the MRC-Human Nutrition Research centre in Cambridge, England. Since 2018, I am a Visiting Scientist with the Fitzgerald Lab at the Early Cancer Institute (formerly MRC Cancer Unit) at the University of Cambridge, to further enhance interdisciplinary research efforts in oesophageal cancer as part of a Cancer Research UK funded Career Establishment Award.
Teaching
Dissertation supervisor
- Postgraduate research: I have supervised 9 PhD, 1 MD and 1 MPhil postgraduate research students to completion. I am currently supervising 6 PhD students (2 as primary supervisor), 1 MD and 1 MPhil student. I have experience in supervising clinical trainees from Gastroenterology, General Practice, Oncology and Surgery specialites. Students have originated from the UK, Ireland, Vietnam, China, Turkey, Uganda and Angola.
- Masters in Public Health: I mentor and supervise 1 MPH student dissertation each year.
- BSc Human Biology; BSc Biomedical Sciences; BSc Intercalating Medical Sciences: I usually supervise 1-2 BSc dissertation students each year.
Undergraduate teaching
- BMS 2109 Public Health Sciences module co-ordinator
- Case-based learning facilitator, 1st year Medicine
Other teaching roles
I deliver tutorials and lectures on population research, study designs, global cancer incidence trends, nutrition and cancer epidemiology to undergraduate Medicine, and postgraduate Masters in Public Health and Masters in Molecular Pathology students. I was Module co-ordinator of the 3rd year Spring Student Selected Components from 2013-2018.
Achievements
- Chair of the Trial Steering Committee for the BEST4 Trial: A Platform Trial to determine whether Cytosponge-biomarker technology reduces mortality from oesophageal cancer (2023-ongoing)
- Co-Chair International Cancer Benchmarking Partnership (ICBP) Oesophageal Network (2022-ongoing)
- Lead of Cancer Epidemiology Research Group, member of Senior Management Team, Centre for Public Health, 2018-ongoing
- (Acting) Deputy Director of Northern Ireland Cancer Registry 2020-ongoing
- QUB Patient and Public Involvement Working group, 2023-ongoing
- Chair, Independent Data Monitoring Committee for the CONSCOP2 Trial, 2020-ongoing
- Cancer Research UK Population Research Committee funding panel member 2018-ongoing
- Yorkshire Cancer Research Fund Research Advisory Panel member 2020-ongoing
- Elected member of the Oesophageal Section Committee, British Society of Gastroenterology 2023- ongoing.
- Member, The Pathological Society of Great Britain and Ireland (Membership number Application Reference Number: 1379)
- Board Member, OCHRE (Nov 2021-ongoing)
- Fellow of The Higher Education Academy
- Associate Member, British Society of Gastroenterology (2010-ongoing)
- Member, Irish Society of Gastroenterology (Membership number 368) 2022-ongoing.
- Scientific Officer, Ulster Society of Gastroenterology committee 2017-2021
- International Molecular Pathology Epidemiology 'Rising Investigator' award 2016
- Queen’s Gender Initiative Mentor 2015-ongoing
- Cancer Research UK Population Research Postdoctoral Fellowship 2013-2015
- Associate member of the British Society of Gastroenterology 2010-ongoing
- World Cancer Research Fund International Fellow 2010
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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R2788CPH: Colorectal cancer in Uganda: exploring prevention strategies
McShane, C. (PI) & Coleman, H. (CoI)
30/03/2021 → …
Project: Research
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R2643CNR: Bioinformatic stratification of stage II/III colorectal cancer patients
Overton, I. (PI), Coleman, H. (CoI) & Miller, P. (CoI)
06/10/2019 → 31/03/2024
Project: Research
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R1917CNR: Health Data Research UK (HDR UK)
Lawler, M. (PI), Blayney, J. (CoI), Coleman, H. (CoI), Dunne, P. (CoI), Heaney, L. (CoI), Kee, F. (CoI), McArt, D. (CoI), Nikolopoulos, D. (CoI), O'Reilly, D. (CoI), Overton, I. (CoI), Salto-Tellez, M. (CoI) & Woods, R. (CoI)
29/10/2018 → 31/03/2023
Project: Research
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R2421CNR: Impact of chemotherapy on anti-cancer immunity in molecular-stratified subgroups of colorectal cancer
Longley, D. (PI), Coleman, H. (CoI), Dunne, P. (CoI), Lawler, M. (CoI), McArt, D. (CoI) & McDade, S. (CoI)
03/07/2017 → 31/01/2023
Project: Research
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Disentangling oncogenic amplicons in esophageal adenocarcinoma
Ng, A. W. T., McClurg, D. P., Wesley, B., Zamani, S. A., Black, E., Miremadi, A., Giger, O., Hoopen, R. T., Devonshire, G., Redmond, A. M., Grehan, N., Jammula, S., Blasko, A., Li, X., Aparicio, S., Tavaré, S., Edwards, P. A. W., Grehan, N., Nutzinger, B. & Loreno, C. & 31 others, , 14 May 2024, In: Nature Communications. 15, 4074.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)7 Downloads (Pure) -
Factors associated with interobserver variation amongst pathologists in the diagnosis of endometrial hyperplasia: a systematic review
McCoy, C. A., Coleman, H. G., McShane, C. M., McCluggage, W. G., Wylie, J., Quinn, D. & McMenamin, Ú. C., 29 Apr 2024, In: PLoS One. 19, 4, 19 p., 0302252.Research output: Contribution to journal › Article › peer-review
Open AccessFile45 Downloads (Pure) -
Impact of COVID-19 on acute appendicitis presentation, management and pathology findings in adult and paediatric populations
Johnston, D. B., Coleman, H. G., Colvin, D., Lawther, S. & Loughrey, M. B., 17 Apr 2024, In: PLoS One. 19, 4, 13 p., e0300357.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)44 Downloads (Pure) -
Multicentre validation of CT grey-level co-occurrence matrix features for overall survival in primary oesophageal adenocarcinoma
O’Shea, R., Withey, S. J., Owczarczyk, K., Rookyard, C., Gossage, J., Godfrey, E., Jobling, C., Parsons, S. L., Skipworth, R. J. E., Goh, V., Crosby, T. D. L., Bartlett, F., Petty, R. D., Coleman, H., McManus, D., Turkington, R., Grabowska, A., Moorthy, K., Peters, C. J. & Hanna, G. B. & 31 others, , Oct 2024, In: European Radiology. 34, 10, p. 6919-6928 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Downloads (Pure) -
Multi-omic analysis of esophageal adenocarcinoma uncovers candidate therapeutic targets and cancer-selective posttranscriptional regulation
Robert O'Neill, J., Mayordomo, M. Y., Mitulović, G., Al Shboul, S., Bedran, G., Faktor, J., Hernychova, L., Uhrik, L., Gómez-Herranz, M., Kocikowski, M., Save, V., Vojtěšek, B., Arends, M. J., Hupp, T., Alfaro, J. A., Fitzgerald, R. C., Edwards, P. A. W., Grehan, N., Nutzinger, B. & Loreno, C. & 31 others, , 19 Jun 2024, In: Molecular and Cellular Proteomics. 23, 6, 100764.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)9 Downloads (Pure)
Prizes
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1st prize, Poster presentation
Coleman, H. (Recipient), 09 Oct 2015
Prize: Prize (including medals and awards)
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2nd prize, Poster presentation (Jointly with Andrew Kunzmann)
Coleman, H. (Recipient), May 2015
Prize: Prize (including medals and awards)
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Best oral presentation
Coleman, H. (Recipient), 10 Apr 2014
Prize: Prize (including medals and awards)
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Cancer Research UK Career Establishment Award
Coleman, H. (Recipient), 2018
Prize: Fellowship awarded competitively
Activities
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How has the era of endoscopic therapeutic interventions influenced Oesophageal Cancer epidemiology?
Coleman, H. (Invited speaker)
Jun 2024Activity: Talk or presentation types › Invited or keynote talk at national or international conference
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Cancer risk stratification in non-dysplastic Barrett's oesophagus: Biomarkers and conventional risk factors - Can we tailor surveillance to individual risk?
Coleman, H. (Invited speaker)
Jun 2024Activity: Talk or presentation types › Invited or keynote talk at national or international conference
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Cancer prevention research: opportunities to build your career
Coleman, H. (Invited speaker)
18 Mar 2024Activity: Talk or presentation types › Invited talk
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Professor Liam Murray Cancer Epidemiology symposium 2024: Insights and Debates from Pharmacoepidemiology in Cancer Research
Coleman, H. (Organiser)
Jan 2024Activity: Participating in or organising an event types › Participation in conference
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Press/Media
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NI Cancer Registry report reveals soaring rates of pancreatic cancer
01/03/2023
1 item of Media coverage, 2 Media contributions
Press/Media: Research
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Breakthrough Cancer Research: Launch of All-Ireland Cancer Network (All CaN) in Oesophageal Cancer
Coleman, H., Turkington, R., Johnson, B. T., Middleton, D., Kunzmann, A., Cairnduff, V., Hamilton, A., McManus, D., Reid, H., Dempster, M., Santin, O., Craig, S., Murray, D., Gavin, A., Bennett, K., Cardwell, C., Bennett, D., O’Sullivan, J., Hussey, J., McManus, D. & Bennett, D.
04/02/2023 → 05/02/2023
6 items of Media coverage
Press/Media: Research
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Medscape News UK: Immune Status is Prognostic for Poor Survival in Colorectal Cancer
Craig, S., Humphries, M., Alderdice, M., Bingham, V., Richman, S., Loughrey, M., Coleman, H., Viratham Pulsawatdi, A., McCombe, K., Graeme, M., Blake, A., Domingo, E., Robineau, J., Brown, L., Fisher, D., Seymour, M., Quirke, P., Bankhead, P., McQuaid, S., Lawler, M., McArt, D., Maughan, T., James, J. & Salto-Tellez, M.
24/07/2020
1 item of Media coverage
Press/Media: Research
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Career advice: how to transition from PhD student to senior lecturer
08/03/2018
1 Media contribution
Press/Media: Other
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Invited Guest Blog: Older people & cancer
16/06/2015
1 Media contribution
Press/Media: Public Engagement Activities
Impacts
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Re-assessment of Cancer risk in Barrett’s oesophagus.
Yousef, F. (Participant), Cardwell, C. (Participant), Cantwell, M. (Participant), Galway, K. (Participant), Murray, L. (Participant), Anderson, L. (Participant), Murphy, S. (Participant), Fitzpatrick, D. (Participant), Johnston, B. (Participant), Watson, P. (Participant), McCarron, P. (Participant), Gavin, A. (Participant), Bhat, S. (Participant), Coleman, H. (Participant), McManus, D. (Participant) & Coleman, H. (Participant)
Impact: Health Impact, Quality of Life Impact