Projects per year
Personal profile
Research Interests
I am Lead of the Cancer Epidemiology Research Group at the Centre for Public Health at Queen's University Belfast. I am Deputy Director of the Northern Ireland Cancer Registry.
My research mostly focuses on the epidemiology and early detection of gastrointestinal cancers and conditions, including pre-malignant conditions. I have particular interests in:
- Barrett's oesophagus and oesophageal adenocarcinoma (major ongoing studies include: PI of the Northern Ireland Barrett's oesophagus register; OCCAMS consortium sub-study investigator)
- Colorectal polyps and colorectal cancer (major ongoing studies include: NI Biobank Epi700 cohort; NI Bowel Cancer Screening pathology data analysis; Early-onset colorectal cancer studies).
- Modifiable risk factors, such as smoking, alcohol and nutrition, in cancer risk and progression
- Gastrointestinal pathology diagnosis trends and concordance (member of the International Barrett's Pathology Working Group)
I have expertise in molecular epidemiology (incuding molecular pathology epidemiology) studies, statistical analysis of population-based disease registers and real world evidence, and systematic reviews of lifestyle factors and biomarkers in cancer risk and progression.
I place considerable emphasis on interdisciplinary research, and am affiliated to the Patrick G. Johnston Centre for Cancer Research at Queen's University Belfast. I have previously spent time conducting research at Vanderbilt University, Nashville, TN, USA, Ulster University, and at the MRC-Human Nutrition Research centre in Cambridge, England. Since 2018, I am a Visiting Scientist with the Fitzgerald Lab at the Early Cancer Institute (formerly MRC Cancer Unit) at the University of Cambridge, to further enhance interdisciplinary research efforts in oesophageal cancer as part of a Cancer Research UK funded Career Establishment Award.
Teaching
Dissertation supervisor
- Postgraduate research: I have supervised 9 PhD, 1 MD and 1 MPhil postgraduate research students to completion. I am currently supervising 6 PhD students (2 as primary supervisor), 1 MD and 1 MPhil student. I have experience in supervising clinical trainees from Gastroenterology, General Practice, Oncology and Surgery specialites. Students have originated from the UK, Ireland, Vietnam, China, Turkey, Uganda and Angola.
- Masters in Public Health: I mentor and supervise 1 MPH student dissertation each year.
- BSc Human Biology; BSc Biomedical Sciences; BSc Intercalating Medical Sciences: I usually supervise 1-2 BSc dissertation students each year.
Undergraduate teaching
- BMS 2109 Public Health Sciences module co-ordinator
- Case-based learning facilitator, 1st year Medicine
Other teaching roles
I deliver tutorials and lectures on population research, study designs, global cancer incidence trends, nutrition and cancer epidemiology to undergraduate Medicine, and postgraduate Masters in Public Health and Masters in Molecular Pathology students. I was Module co-ordinator of the 3rd year Spring Student Selected Components from 2013-2018.
Achievements
- Cancer Research UK Population Research Committee funding panel member 2018-ongoing
- Yorkshire Cancer Research Fund Research Advisory Panel member 2020-ongoing
- Ulster Society of Gastroenterology committee Scientific Officer 2017-2021
- International Molecular Pathology Epidemiology 'Rising Investigator' award 2016
- Cancer Research UK Population Research Postdoctoral Fellowship 2013-2015
- Associate member of the British Society of Gastroenterology 2010-ongoing
- World Cancer Research Fund International Fellow 2010
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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R2788CPH: Colorectal cancer in Uganda: exploring prevention strategies
30/03/2021 → …
Project: Research
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R2643CNR: Bioinformatic stratification of stage II/III colorectal cancer patients
Overton, I., Coleman, H. & Miller, P.
06/10/2019 → …
Project: Research
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R1917CNR: Health Data Research UK (HDR UK)
Lawler, M., Blayney, J., Coleman, H., Dunne, P., Heaney, L., Kee, F., McArt, D., Nikolopoulos, D., O'Reilly, D., Overton, I., Salto-Tellez, M. & Woods, R.
29/10/2018 → …
Project: Research
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R2421CNR: Impact of chemotherapy on anti-cancer immunity in molecular-stratified subgroups of colorectal cancer
Longley, D., Coleman, H., Dunne, P., Lawler, M., McArt, D. & McDade, S.
03/07/2017 → 31/01/2023
Project: Research
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Author Correction: Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features
Flanagan, D. J., Amirkhah, R., Vincent, D. F., Gunduz, N., Gentaz, P., Cammareri, P., McCooey, A. J., McCorry, A. M. B., Fisher, N. C., Davis, H. L., Ridgway, R. A., Lohuis, J., Leach, J. D. G., Jackstadt, R., Gilroy, K., Mariella, E., Nixon, C., Clark, W., Hedley, A., Markert, E. K., & 19 others , 31 Jan 2023, In: Nature Communications. 14, p. 522Research output: Contribution to journal › Article › peer-review
Open Access -
Dietary Inflammatory potential and the risk of serrated and adenomatous colorectal polyps
Getty, B., Coleman, H., Shivappa, N., Hebert, J., Murff, H., Milne, G., Ness, R., Smalley, W., Zheng, W. & Shrubsole, M., 05 Sep 2023, (Accepted) In: Nutrition and Cancer.Research output: Contribution to journal › Article › peer-review
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Distinct molecular profiles of sporadic early onset colorectal cancer: a population-based cohort and systematic review
Hamilton, A. C., Bannon, F. J., Dunne, P. D., James, J., McQuaid, S., Gray, R. T., Salto-Tellez, M., Cardwell, C. R., Loughrey, M. B. & Coleman, H. G., 01 Mar 2023, In: Gastro Hep Advances. 2, 3, p. 347-359 13 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile19 Downloads (Pure) -
Field synopsis of environmental and genetic risk factors of sporadic early-onset colorectal cancer and advanced adenoma
Zhang, R., Boakye, D., Yang, N., Zhou, X., Zhou, Y., Jiang, F., Yu, L., Wang, L., Sun, J., Yuan, S., Chen, J., Coleman, H. G., Larsson, S. C., Little, J., Dunlop, M. G., Giovannucci, E. L., Theodoratou, E. & Li, X., 23 May 2023, (Early online date) In: Cancer Epidemiology Biomarkers & Prevention.Research output: Contribution to journal › Article › peer-review
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Mutational signature dynamics shaping the evolution of oesophageal adenocarcinoma
Abbas, S., Pich, O., Devonshire, G., Zamani, S. A., Katz-Summercorn, A., Killcoyne, S., Cheah, C., Nutzinger, B., Grehan, N., Lopez-Bigas, N., Edwards, P. A. W., Fidziukiewicz, E., Redmond, A. M., Freeman, A., Smyth, E. C., O’Donovan, M., Miremadi, A., Malhotra, S., Tripathi, M., Coles, H., & 31 others , 15 Jul 2023, In: Nature Communications. 14, 1, 16 p., 4239.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure)
Prizes
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1st prize, Poster presentation
Coleman, Helen (Recipient), 09 Oct 2015
Prize: Prize (including medals and awards)
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1st prize oral presentation
Coleman, Helen (Recipient), 2013
Prize: Prize (including medals and awards)
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2nd prize, Poster presentation (Jointly with Andrew Kunzmann)
Coleman, Helen (Recipient), May 2015
Prize: Prize (including medals and awards)
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Best oral presentation
Coleman, Helen (Recipient), 10 Apr 2014
Prize: Prize (including medals and awards)
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Population Health Postdoctoral Fellowship
Coleman, Helen (Recipient), 2013
Prize: Fellowship awarded competitively
Activities
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Association of University Departments of General Practice in Ireland 2023
Orla O'Neill (Contributor), Helen Coleman (Contributor) & Helen Reid (Presenter)
03 Mar 2023Activity: Participating in or organising an event types › Participation in conference
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Celebrating Ada Lovelace Day: PGJCCR in partnership with QGI
Ian Overton (Organiser), Helen Coleman (Invited speaker), Emma Allott (Invited speaker), Kelsey McCulloch (Invited speaker), Karen McCloskey (Contributor) & Kerrie-Ann Forsythe (Contributor)
11 Oct 2022Activity: Participating in or organising an event types › Participation in workshop, seminar, course
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Gastroenterology (Journal)
Helen Coleman (Editorial board member)
Jan 2020Activity: Publication peer-review and editorial work types › Editorial activity
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Cancer Research UK (External organisation)
Helen Coleman (Advisor)
2018 → …Activity: Membership types › Membership of peer review panel or committee
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European Society for Diseases of the Esophagus
Helen Coleman (Invited speaker)
10 Nov 2017Activity: Participating in or organising an event types › Participation in conference
Press/Media
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Breakthrough Cancer Research: Launch of All-Ireland Cancer Network (All CaN) in Oesophageal Cancer
Helen Coleman, Richard Turkington, Brian T Johnson, Dan Middleton, Andrew Kunzmann, Victoria Cairnduff, Ashleigh Hamilton, Damien McManus, Helen Reid, Martin Dempster, Olinda Santin, Stephanie Craig, Deirdre Murray, Anna Gavin, Kathleen Bennett, Christopher Cardwell, Damien Bennett, Jacintha O’Sullivan, Juliette Hussey, Damian McManus & Damien Bennett
04/02/2023 → 05/02/2023
6 items of Media coverage
Press/Media: Research
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Medscape News UK: Immune Status is Prognostic for Poor Survival in Colorectal Cancer
Stephanie Craig, Matthew Humphries, Matthew Alderdice, Victoria Bingham, Susan Richman, Maurice Loughrey, Helen Coleman, Amélie Viratham Pulsawatdi, Kris McCombe, Murray Graeme, Andrew Blake, Enric Domingo, James Robineau, Louise Brown, David Fisher, Matt Seymour, Phil Quirke, Peter Bankhead, Stephen McQuaid, Mark Lawler, Darragh McArt, Tim Maughan, Jacqueline James & Manuel Salto-Tellez
24/07/2020
1 item of Media coverage
Press/Media: Research
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Career advice: how to transition from PhD student to senior lecturer
08/03/2018
1 Media contribution
Press/Media: Other
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Invited Guest Blog: Older people & cancer
16/06/2015
1 Media contribution
Press/Media: Public Engagement Activities
Impact
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Re-assessment of Cancer risk in Barrett’s oesophagus.
Fouad Yousef (Participant), Christopher Cardwell (Participant), Marie Cantwell (Participant), Karen Galway (Participant), Liam Murray (Participant), Lesley Anderson (Participant), Suzanne Murphy (Participant), Deirdre Fitzpatrick (Participant), Brian Johnston (Participant), Robert Watson (Participant), Peter McCarron (Participant), Anna Gavin (Participant), Shivaram Bhat (Participant), Helen Coleman (Participant), Damian McManus (Participant) & Helen Coleman (Participant)
Impact: Health Impact, Quality of Life Impact