Projects per year
Personal profile
Research Interests
Stem cells and regenerative therapies
Orofacial pain
Minimal intervention dentistry
Oral infections and systemic health
Research Statement
The goal of my research is to develop minimally invasive, biologically based therapies for inflammatory dental diseases. I have particular interest in investigating the link between pain, inflammation and regeneration as well as the implications of dental disease on general health. The current research programmes include:
1- Exploring potential strategies for optimal differentiation of dental pulp stem cells with particular focus on inflammation and its impact on regeneration
2- Developing in vitro and in vivo models to study neuronal signalling in inflammatory and neuropathic pain
3- Investigate potential links between dental infections, systemic inflammation and general heath.
Fingerprint
Dive into the research topics where Ikhlas El Karim is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
R4826CEM: Endodontic infections and CardiOvascular disease risk (ECO): A prospective study of a possible link?
El Karim, I., Linden, G. & Lundy, F.
08/06/2018 → …
Project: Research
-
R2258CII: Mas related gene receptors as novel modules for pain relief
El Karim, I., Curtis, T. & Lundy, F.
16/12/2015 → …
Project: Research
-
R2570RED: Molecular mechanisms in detine sensitivity and pain <MEDICI/BIOMED>
El Karim, I., Curtis, T. & Lundy, F.
01/08/2007 → …
Project: Research
-
Apical Periodontitis and All-Cause Mortality Among 60-70 Year-Old Men
McClory, M., Lundy, F., Winning, L., Linden, G. & El Karim, I., 05 Feb 2021, In: Journal of Dental Research. 100, Spec IssBResearch output: Contribution to journal › Meeting abstract › peer-review
-
Authors’ response
El Karim, I. A., Jul 2021, In: International Endodontic Journal. 54, 7, p. 1208 1 p.Research output: Contribution to journal › Letter
-
Deciphering Reparative Processes in the Inflamed Dental Pulp
El karim, I. A., Cooper, P. R., About, I., Tomson, P. L., Lundy, F. T. & Duncan, H. F., 31 Mar 2021, In: Frontiers in Dental Medicine. 2, 10 p., 651219.Research output: Contribution to journal › Review article › peer-review
Open AccessFile16 Downloads (Pure) -
DNA Released by Dying Cells Induces CGAS-STING Mediated Pulp Inflammation
Al-Natour, B., Lundy, F., Dombrowski, Y., About, I. & El Karim, I., 05 Feb 2021, In: Journal of Dental Research. 100, Spec IssBResearch output: Contribution to journal › Meeting abstract › peer-review
-
Endogenous Mas-related G-protein-coupled receptor X1 activates and sensitizes TRPA1 in a human model of peripheral nerves
McMillan, H., Lundy, F. T., Dunne, O. M., Al-Natour, B., Jeanneau, C., About, I., Curtis, T. M. & El Karim, I., 01 May 2021, In: The FASEB Journal. 35, 5, p. e21492 e21492.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Downloads (Pure)
Prizes
-
British Endodontic Society Research Poster Prize awarded to Mary McClory (Primary Supervisor Ikhlas El Karim)
El Karim, Ikhlas (Recipient), 2019
Prize: Prize (including medals and awards)
-
Dental Health Foundation Award awarded to Mary McClory (primary supervisor Ikhlas El karim)
El Karim, Ikhlas (Recipient), 2021
Prize: Prize (including medals and awards)
-
Elected Fellow of the Royal College of Surgeons Edinburgh
El Karim, Ikhlas (Recipient), 2014
Prize: Prize (including medals and awards)
-
Fellowship (Ad Eundem) Royal college of Surgeons in Ireland
El Karim, Ikhlas (Recipient), 2016
Prize: Prize (including medals and awards)
-
President of the Irish Division of IADR
El Karim, Ikhlas (Recipient), 2020
Prize: Prize (including medals and awards)
Activities
-
Irish Division of IADR virtual meeting
Ikhlas El Karim (Chair)
05 Feb 2021Activity: Participating in or organising an event types › Participation in conference
-
IADR General Session Boston 2021: New insights into pulpitis management: Can we reverse the irreversible?
Ikhlas El Karim (Invited speaker)
Jul 2021Activity: Talk or presentation types › Invited talk
-
NIMDTA MFDS Preparatory Course
Ikhlas El Karim (Lecturer)
10 Mar 2021Activity: Participating in or organising an event types › Participation in workshop, seminar, course
-
School of Medicine, Dentistry and Biomedical Sciences Racial equality Champion
Ikhlas El Karim (Contributor)
Mar 2021Activity: Other activity types › Other
-
Pulp Biology and Regeneration Group Symposium: Evolving Therapies to Maintain Vital DentinPulp Complex: 100-years of Innovation: IADR General Session Boston 2021
Ikhlas El Karim (Organiser)
24 Jul 2021Activity: Participating in or organising an event types › Participation in conference
Press / Media
-
-
Belfast scientists say aspirin could reverse tooth decay.
07/09/2017
1 item of Media coverage
Press/Media: Research
-
Thesis
-
Neuropeptide Y and vasoactive intestinal polypeptide in human dental pulps from carious and non-carious teeth
Author: El Karim, I., 2003Supervisor: Lundy, F. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy