Research Output per year
Personal profile
Research Interests
Stem cells and regenerative therapies
Orofacial pain
Minimal intervention dentistry
Oral infections and systemic health
Research Statement
The goal of my research is to develop minimally invasive, biologically based therapies for inflammatory dental diseases. I have particular interest in investigating the link between pain, inflammation and regeneration as well as the implications of dental disease on general health. The current research programmes include:
1- Exploring potential strategies for optimal differentiation of dental pulp stem cells with particular focus on inflammation and its impact on regeneration
2- Developing in vitro and in vivo models to study neuronal signalling in inflammatory and neuropathic pain
3- Investigate potential links between dental infections, systemic inflammation and general heath.
Fingerprint Dive into the research topics where Ikhlas El Karim is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 7 Similar Profiles
Dental Pulp
Medicine & Life Sciences
Tooth
Medicine & Life Sciences
Transient Receptor Potential Channels
Medicine & Life Sciences
Neuropeptide Y
Medicine & Life Sciences
Endodontics
Medicine & Life Sciences
Odontoblasts
Medicine & Life Sciences
Neuropeptides
Medicine & Life Sciences
Vasoactive Intestinal Peptide
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Research Output 2001 2019
A Comparative Analysis of the Osteogenic Potential of Dental Mesenchymal Stem Cells
Winning, L., El Karim, I. A. & Lundy, F. T., 01 Aug 2019, In : Stem Cells and Development. 28, 15, p. 1050-1058 9 p.Research output: Contribution to journal › Article
Dental Pulp
Mesenchymal Stromal Cells
Deciduous Tooth
Tooth
Periodontal Ligament
Current and Future Views on Pulpal Pain and Neurogenesis
Lundy, F., El Karim, I. & Scheven, B., 2019, Clinical Approaches in Endodontic Regeneration, Current and Emerging Therapeutic Perspectives. Springer Nature Switzerland, p. 19-36Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed)
European Society of Endodontology position statement: Management of deep caries and the exposed pulp: Management of deep caries and the exposed pulp
European Society of Endodontology (ESE) developed by:, 01 Jul 2019, In : International Endodontic Journal. 52, 7, p. 923-934 12 p.Research output: Contribution to journal › Article
Endodontics
Periapical Periodontitis
Uncertainty
Consensus
Tooth
Pulpotomy for mature carious teeth with symptoms of irreversible pulpitis: A systematic review
Cushley, S., Duncan, H. F., Lappin, M., Tomson, P. L., Lundy, F. T., Cooper, P., Clarke, M. & El Karim, I. A., 20 Jun 2019, In : Journal of Dentistry.Research output: Contribution to journal › Review article
Pulpotomy
Pulpitis
Tooth
Signs and Symptoms
Dental Pulp Cavity
A Comparative Analysis of the Osteogenic Differentiation Potential of Intra-subject Dental Mesenchymal Stem Cells
Winning, L., El Karim, I., Linden, G., Irwin, C. & Lundy, F., 2018.Research output: Contribution to conference › Poster
Activities 2006 2019
ESE Pre-congress symposium: Designing and running Randomised Control Trials and laboratory research projects
Ikhlas El Karim (Invited speaker)11 Sep 2019
Activity: Talk or presentation types › Invited talk
To RCT or NOT?
Ikhlas El Karim (Invited speaker)27 Sep 2019
Activity: Talk or presentation types › Invited talk
Identification of novel biomarkers and therapeutic agents for pulpitis using sscMAP
Ikhlas El Karim (Presenter)04 Sep 2019
Activity: Talk or presentation types › Oral presentation
Bioinformatics approach to optimise DPSCs osteo/odontogenic differentiation
Ikhlas El Karim (Keynote speaker)25 Jul 2018 → …
Activity: Talk or presentation types › Invited or keynote talk at national or international conference
96th General Session & Exhibition of the IADR
Ikhlas El Karim (Organiser)28 Jul 2018
Activity: Participating in or organising an event types › Participation in conference
Thesis
Neuropeptide Y and vasoactive intestinal polypeptide in human dental pulps from carious and non-carious teeth
Author: El Karim, I., 2003Supervisor: Lundy, F. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy