Projects per year
Personal profile
Research Interests
Stem cells and regenerative therapies
Orofacial pain
Minimal intervention dentistry
Oral infections and systemic health
Research Statement
The goal of my research is to develop minimally invasive, biologically based therapies for inflammatory dental diseases. I have particular interest in investigating the link between pain, inflammation and regeneration as well as the implications of dental disease on general health. The current research programmes include:
1- Exploring potential strategies for optimal differentiation of dental pulp stem cells with particular focus on inflammation and its impact on regeneration
2- Developing in vitro and in vivo models to study neuronal signalling in inflammatory and neuropathic pain
3- Investigate potential links between dental infections, systemic inflammation and general heath.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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R4826CEM: Endodontic infections and CardiOvascular disease risk (ECO): A prospective study of a possible link?
El Karim, I., Linden, G. & Lundy, F.
08/06/2018 → …
Project: Research
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R2258CII: Mas related gene receptors as novel modules for pain relief
El Karim, I., Curtis, T. & Lundy, F.
16/12/2015 → …
Project: Research
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R2570RED: Molecular mechanisms in detine sensitivity and pain <MEDICI/BIOMED>
El Karim, I., Curtis, T. & Lundy, F.
01/08/2007 → …
Project: Research
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Establishing a Core Outcome Set for Endodontic Treatment modalities
El Karim, I., Duncan, H. F., Cushley, S., Nagendrababu, V., Kirkevang, L-L., Kruse, C., Chong, B. S., Shah, P. K., Lappin, M. J., McLister, C., Lundy, F. T. & Clarke, M., Jul 2022, In: International Endodontic Journal. 55, 7, p. 696-699Research output: Contribution to journal › Editorial › peer-review
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Novel Antibacterial Properties of the Human Dental Pulp Multipotent Mesenchymal Stromal Cell Secretome
Ravenscroft, H., El Karim, I., Krasnodembskaya, A. D., Gilmore, B., About, I. & Lundy, F. T., 06 Jun 2022, In: The American journal of pathology. 192, 6, p. 956-969Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Downloads (Pure) -
Outcomes reporting in systematic reviews on non‐surgical root canal treatment: A scoping review for the development of a core outcome set
Kirkevang, LL., El Karim, I. A., Duncan, H. F., Nagendrababu, V. & Kruse, C., 22 Aug 2022, (Early online date) In: International Endodontic Journal.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Downloads (Pure) -
Outcomes reporting in systematic reviews on surgical endodontics: A scoping review for the development of a core outcome set
Shah, P. K., El Karim, I., Duncan, H. F., Nagendrababu, V. & Chong, B. S., 25 May 2022, (Early online date) In: International Endodontic Journal.Research output: Contribution to journal › Article › peer-review
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Outcomes reporting in systematic reviews on vital pulp treatment: A scoping review for the development of a core outcome set
Cushley, S., Duncan, H. F., Lundy, F. T., Nagendrababu, V., Clarke, M. & El Karim, I., 15 Jun 2022, (Early online date) In: International Endodontic Journal.Research output: Contribution to journal › Article › peer-review
Open Access
Prizes
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British Endodontic Society Research Poster Prize awarded to Mary McClory (Primary Supervisor Ikhlas El Karim)
El Karim, Ikhlas (Recipient), 2019
Prize: Prize (including medals and awards)
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Dental Health Foundation Award awarded to Mary McClory (primary supervisor Ikhlas El karim)
El Karim, Ikhlas (Recipient), 2021
Prize: Prize (including medals and awards)
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Elected Fellow of the Royal College of Surgeons Edinburgh
El Karim, Ikhlas (Recipient), 2014
Prize: Prize (including medals and awards)
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Fellowship (Ad Eundem) Royal college of Surgeons in Ireland
El Karim, Ikhlas (Recipient), 2016
Prize: Prize (including medals and awards)
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President of the Irish Division of IADR
El Karim, Ikhlas (Recipient), 2020
Prize: Prize (including medals and awards)
Activities
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The CHOICE Trial Northern Ireland Launch Event
Marc Edwards (Participant), Pauline Adair (Host), Nicola Carlin (Organiser), Cynthia Pine (Keynote/plenary speaker), Ikhlas El Karim (Host) & Conal Baxter (Invited speaker)
28 Jun 2022Activity: Participating in or organising an event types › Participation in workshop, seminar, course
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Pulpotomy training for General Dental Practitioners
Mark Lappin (Speaker), Ikhlas El Karim (Speaker) & Siobhan Cushley (Organiser)
22 Sep 2021Activity: Participating in or organising an event types › Participation in workshop, seminar, course
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Pulp Biology and Regeneration Group Symposium: Evolving Therapies to Maintain Vital DentinPulp Complex: 100-years of Innovation: IADR General Session Boston 2021
Ikhlas El Karim (Organiser)
24 Jul 2021Activity: Participating in or organising an event types › Participation in conference
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IADR General Session Boston 2021: New insights into pulpitis management: Can we reverse the irreversible?
Ikhlas El Karim (Invited speaker)
Jul 2021Activity: Talk or presentation types › Invited talk
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NIMDTA MFDS Preparatory Course
Ikhlas El Karim (Lecturer)
10 Mar 2021Activity: Participating in or organising an event types › Participation in workshop, seminar, course
Press / Media
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Belfast scientists say aspirin could reverse tooth decay.
07/09/2017
1 item of Media coverage
Press/Media: Research
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Thesis
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Neuropeptide Y and vasoactive intestinal polypeptide in human dental pulps from carious and non-carious teeth
Author: El Karim, I., 2003Supervisor: Lundy, F. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy