Projects per year
Personal profile
Research Statement
My research work stands on three main pillars: 1) Basic Research; 2) Clinical collaborations; 3) Translational work. Since joining QUB in September 2016 I am working on establishing a research program to develop an interdisciplinary program to build a firm foundation for these three pillars with the final aim to help to deliver better patient care. I built firm relationships with Industry and in the process of establishing closer ties with big pharma as well as SMEs. In addition to the international research network I am building since I started research I built several close collaborations at QUB. The works we carry out as part of the EU funded Eye-Risk project as well as the soon to be starting Deep and Frequent Phenotyping Study for Alzheimer's disease for which I am the Ophthalmology Team Lead, we will be able to influence clinical pathways as well as health policy. These activities are underpinned by an active dissemination program. We had press releases as well as feature articles on our work and participate in science fairs and festivals and regularly meet patient groups to inform them about the need and use of research for conditions affecting them.
Teaching
Advanced Neuroscience Course: The eye as a window to the brain.
The organizer of student-selected component: Imaging and image analysis in medicine for 3rd-year medical students.
The module coordinator for the MSc in Experimental Medicine: Fundamental Research Skills.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
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R8576CEM: The molecular underpinning of eye and brain calcification
Lengyel, I. (PI), Costa, G. (CoI) & Lamprou, D. (CoI)
07/12/2023 → …
Project: Research
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R2733CPH: Using data science to determine the best combination of factors for the diagnosis of AMD and to detect clinical change over time
Hogg, R. (PI), Hua, Y. (CoI), Kee, F. (CoI), Lengyel, I. (CoI), McKnight, A. J. (CoI), Sousa, J. (CoI) & Wright, D. (CoI)
03/08/2020 → …
Project: Research
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R2659CEM: MonCvOne elctrophysiology module
Lengyel, I. (PI), Hogg, R. (CoI) & Peto, T. (CoI)
28/10/2019 → 08/09/2020
Project: Research
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Applications of artificial intelligence in ophthalmology: an updated comprehensive review
Hashemian, H., Peto, T., Ambrósio Jr, R., Lengyel, I., Kafieh, R., Noori, A. M. & Khorrami-Nejad, M., 16 Sept 2024, In: Journal of Ophthalmic and Vision Research. 19, 3, p. 354-367Research output: Contribution to journal › Review article › peer-review
Open AccessFile8 Downloads (Pure) -
Bruch's membrane calcification in pseudoxanthoma elasticum: comparing histopathology and clinical imaging
Risseeuw, S., Pilgrim, M. G., Bertazzo, S., Brown, C., Csincsik, L., Fearn, S., Thompson, R. B., Bergen, A. A., ten Brink, J. B., Kortvely, E., Spiering, W., van Norel, J. O., van Leeuwen, R. & Lengyel, I., 01 Mar 2024, In: Ophthalmology Science. 4, 2, 15 p., 100416.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)53 Downloads (Pure) -
Development of dual drug loaded-hydrogel scaffold combining microfluidics and coaxial 3D-printing for intravitreal implantation
Zingale, E., Weaver, E., Bertelli, P. M., Lengyel, I., Pignatello, R. & Lamprou, D. A., 15 Nov 2024, In: International Journal of Pharmaceutics. 665, 14 p., 124700.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure) -
Metabolomic changes in tear fluid following zinc biofortification in the BiZiFED nutritional study: a feasibility study
Brown, C. N., Shahzad, B., Zaman, M., Pan, X., Green, B. D., Lowe, N. M. & Lengyel, I., 10 Sept 2024, In: Frontiers in Molecular Biosciences. 11, 13 p., 1421699.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Downloads (Pure) -
Pseudoxanthoma elasticum – Genetics, pathophysiology, and clinical presentation
Pfau Née Hess, K., Lengyel, I., Norel, J.O.-V., Leeuwen, R. V., Risseeuw, S., Leftheriotis, G., Scholl, H. P. N., Feltgen, N., Holz, F. G. & Pfau, M., Sept 2024, In: Progress in Retinal and Eye Research. 102, 18 p., 101274.Research output: Contribution to journal › Review article › peer-review
Open AccessFile2 Citations (Scopus)21 Downloads (Pure)
Datasets
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Data for: The effects of zinc supplementation on primary human retinal pigment epithelium
Emri, E. (Creator), Thompson, R. (Creator), Pao, P. J. (Creator), Lengyel, I. (Creator), Bishar, S. (Creator), Hauck, S. M. (Creator) & Zeng, H. (Creator), Queen's University Belfast, 06 Mar 2018
Dataset
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Dataset for "A Multi-Omics Approach Identifies Key Regulatory Pathways Induced by Long-Term Zinc Supplementation in Human Primary Retinal Pigment Epithelium"
Lengyel, I. (Creator) & Emri, E. (Creator), Queen's University Belfast, 19 Aug 2021
DOI: 10.17034/c0e7a072-9d8e-4e7e-ac52-7dc205a1512e, https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE156452
Dataset
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Hydroxyapatite-binding plasma proteins in Age-related macular degenaration
Arya, S. (Creator), Emri, E. (Creator), Synowsky, S. A. (Creator), Shirran, S. L. (Creator), Barzegar-Befroeid, N. (Creator), Peto, T. (Creator), Botting, C. H. (Creator), Lengyel, I. (Creator) & Stewart, A. J. (Creator), University of St Andrews, 28 Mar 2018
DOI: 10.17034/ab1c7446-508d-4124-9afb-4a0d48d537d6, https://www.ebi.ac.uk/pride/archive/projects/PXD007944
Dataset
Prizes
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British Society for Immunology Outstanding Team Award
Lengyel, I. (Recipient), Fitzgerald, D. (Recipient), Hughes, S. (Recipient), Naughton, M. (Recipient), Kee, R. (Recipient), Dombrowski, Y. (Recipient), McIlwaine, G. (Recipient), Moffat, J. (Recipient), McDonnell, G. (Recipient), McDonnell, G. (Recipient) & Kennedy, F. (Recipient), 25 Apr 2023
Prize: Prize (including medals and awards)
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REVEAL Study Protocol: The Eye in Down Syndrome as a Window to Alzheimer's Disease
Lengyel, Imre (Recipient), 13 Oct 2023
Prize: Prize (including medals and awards)
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Activities
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The role of calcification and drusen in geographic atrophy
Imre Lengyel (Keynote speaker) & Tunde Peto (Keynote speaker)
04 Oct 2024 → 05 Oct 2024Activity: Talk or presentation types › Invited or keynote talk at national or international conference
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Dementia Research Network Ireland Conference 2024
Imre Lengyel (Member of scientific committee)
03 Oct 2024 → 06 Oct 2024Activity: Participating in or organising an event types › Participation in Festival/Exhibition
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External Examiner new BSc ATT program at RCSI
Imre Lengyel (Examiner)
Sept 2024 → Oct 2027Activity: Examination types › UG external examination
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Balmoral Show 2024
Eleni Beli (Participant), Imre Lengyel (Participant) & Tunde Peto (Participant)
18 May 2024Activity: Participating in or organising an event types › Participation in Festival/Exhibition
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48th Annual Atlantic Coast Retina Club & 24th Macula Conference
Imre Lengyel (Invited speaker)
04 Jan 2024 → 06 Jan 2024Activity: Talk or presentation types › Invited talk
Press/Media
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A vakságra helyezték a fókuszt a messziről jött kutatók - Visiting scientist focused on the causes of blindness
30/10/2023
1 item of Media coverage
Press/Media: Research
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Tetracycline-family antibiotics may offer early diagnostic for degenerative eye disease
21/04/2020
1 item of Media coverage
Press/Media: Research
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Tetracycline-family Antibiotics May Offer Early Diagnostic for Degenerative Eye Disease
21/04/2020
1 item of Media coverage
Press/Media: Research
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