Projects per year
Personal profile
Research Statement
My research work stands on three main pillars: 1) Basic Research; 2) Clinical collaborations; 3) Translational work. Since joining QUB in September 2016 I am working on establishing a research program to develop an interdisciplinary program to build a firm foundation for these three pillars with the final aim to help to deliver better patient care. I built firm relationships with Industry and in the process of establishing closer ties with big pharma as well as SMEs. In addition to the international research network I am building since I started research I built several close collaborations at QUB. The works we carry out as part of the EU funded Eye-Risk project as well as the soon to be starting Deep and Frequent Phenotyping Study for Alzheimer's disease for which I am the Ophthalmology Team Lead, we will be able to influence clinical pathways as well as health policy. These activities are underpinned by an active dissemination program. We had press releases as well as feature articles on our work and participate in science fairs and festivals and regularly meet patient groups to inform them about the need and use of research for conditions affecting them.
Teaching
Advanced Neuroscience Course: The eye as a window to the brain.
The organizer of student-selected component: Imaging and image analysis in medicine for 3rd-year medical students.
The module coordinator for the MSc in Experimental Medicine: Fundamental Research Skills.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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R2733CPH: Using data science to determine the best combination of factors for the diagnosis of AMD and to detect clinical change over time
Hogg, R., Hua, Y., Kee, F., Lengyel, I., McKnight, A. J., Sousa, J. & Wright, D.
03/08/2020 → …
Project: Research
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R2659CEM: MonCvOne elctrophysiology module
Lengyel, I., Hogg, R. & Peto, T.
28/10/2019 → 08/09/2020
Project: Research
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Altered zinc homeostasis in a primary cell culture model of the retinal pigment epithelium
Álvarez-Barrios, A., Álvarez, L., Artime, E., García, M., Lengyel, I., Pereiro, R. & González-Iglesias, H., 17 Apr 2023, In: Frontiers in Nutrition. 10, 1124987.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure) -
Artificial intelligence for biomarker discovery in Alzheimer's disease and dementia
Winchester, L. M., Harshfield, E. L., Shi, L., Badhwar, A., Khleifat, A. A., Clarke, N., Dehsarvi, A., Lengyel, I., Lourida, I., Madan, C. R., Marzi, S. J., Proitsi, P., Rajkumar, A. P., Rittman, T., Silajdžić, E., Tamburin, S., Ranson, J. M. & Llewellyn, D. J., 31 Aug 2023, (Early online date) In: Alzheimer's and Dementia.Research output: Contribution to journal › Review article › peer-review
Open Access -
Editorial: Zinc in health and disease management
González-Iglesias, H., Lengyel, I. & Rolles, B., 10 Jul 2023, (Early online date) In: Frontiers in Nutrition. 10, 2 p., 1242840.Research output: Contribution to journal › Editorial › peer-review
Open AccessFile2 Downloads (Pure) -
Fluorescence lifetime imaging of human sub-RPE calcification in vitro following chlortetracycline infusion
Hegde, K. R., Puche, A. C., Szmacinski, H., Fuller, K., Ray, K., Patel, N., Lengyel, I. & Thompson, R. B., 01 Apr 2023, In: International Journal of Molecular Sciences. 24, 7, 6421.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Downloads (Pure) -
Ocular biomarkers for Alzheimer disease dementia: an umbrella review of systematic reviews and meta-analyses
Costanzo, E., Lengyel, I., Parravano, M., Biagini, I., Veldsman, M., Badhwar, A., Betts, M., Cherubini, A., Llewellyn, D. J., Lourida, I., MacGillivray, T., Rittman, T., Tamburin, S., Tai, X. Y. & Virgili, G., 01 Jan 2023, In: JAMA Ophthalmology. 141, 1, p. 84-91Research output: Contribution to journal › Article › peer-review
Datasets
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Dataset for "A Multi-Omics Approach Identifies Key Regulatory Pathways Induced by Long-Term Zinc Supplementation in Human Primary Retinal Pigment Epithelium"
Lengyel, I. (Creator) & Emri, E. (Creator), Queen's University Belfast, 19 Aug 2021
DOI: 10.17034/c0e7a072-9d8e-4e7e-ac52-7dc205a1512e, https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE156452
Dataset
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Data for: The effects of zinc supplementation on primary human retinal pigment epithelium
Emri, E. (Creator), Thompson, R. (Creator), Pao, P. J. (Creator), Lengyel, I. (Creator), Bishar, S. (Creator), Hauck, S. M. (Creator) & Zeng, H. (Creator), Queen's University Belfast, 06 Mar 2018
Dataset
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Hydroxyapatite-binding plasma proteins in Age-related macular degenaration
Arya, S. (Creator), Emri, E. (Creator), Synowsky, S. A. (Creator), Shirran, S. L. (Creator), Barzegar-Befroeid, N. (Creator), Peto, T. (Creator), Botting, C. H. (Creator), Lengyel, I. (Creator) & Stewart, A. J. (Creator), University of St Andrews, 28 Mar 2018
DOI: 10.17034/ab1c7446-508d-4124-9afb-4a0d48d537d6, https://www.ebi.ac.uk/pride/archive/projects/PXD007944
Dataset
Prizes
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British Society for Immunology Outstanding Team Award
Lengyel, Imre (Recipient), Fitzgerald, Denise (Recipient), Hughes, Stella (Recipient), Naughton, Michael (Recipient), Kee, Rachael (Recipient), Dombrowski, Yvonne (Recipient), McIlwaine, Gemma (Recipient), Moffat, Jill (Recipient), McDonnell, Gavin (Recipient), McDonnell, Gavin (Recipient) & Kennedy, Fiona (Recipient), 25 Apr 2023
Prize: Prize (including medals and awards)
File
Activities
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Investigative Opthalmology and Visual Science (Journal)
Imre Lengyel (Associate editor)
01 Nov 2022 → …Activity: Publication peer-review and editorial work types › Editorial activity
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A new mechanisms for the progression to AMD
Imre Lengyel (Invited speaker)
14 Oct 2022Activity: Talk or presentation types › Invited talk
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Early events in AMD
Imre Lengyel (Advisor)
13 Oct 2022 → 15 Oct 2022Activity: Talk or presentation types › Invited talk
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Frontiers in Nutrition (Journal)
Imre Lengyel (Associate editor)
01 Oct 2022Activity: Publication peer-review and editorial work types › Editorial activity
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MS Masterclass
Imre Lengyel (Organiser)
05 Sep 2022 → 06 Sep 2022Activity: Participating in or organising an event types › Participation in conference
Press/Media
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Tetracycline-family antibiotics may offer early diagnostic for degenerative eye disease
21/04/2020
1 item of Media coverage
Press/Media: Other
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Tetracycline-family Antibiotics May Offer Early Diagnostic for Degenerative Eye Disease
21/04/2020
1 item of Media coverage
Press/Media: Expert Comment
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Retinal changes may reflect dementia progression
08/05/2019
1 Media contribution
Press/Media: Expert Comment
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Calcifications identified as risk factors in macular degeneration
13/12/2018
1 Media contribution
Press/Media: Other