Projects per year
Personal profile
Research Interests
Irene is Professor of Microbiology and Food Safety within IGFS. Her long time research interest has been Mycobacterium avium subsp. paratuberculosis, its heat resistance, presence in milk and dairy products, and methods for its accurate detection and enumeration in milk and faeces. She has published extensively on this subject and is recognized as an international authority on this potentially foodborne and zoonotic bacterium. More recently, her research has expanded to include Mycobacterium bovis, the cause of bovine tuberculosis. Irene manages Containment Level 2 and 3 pathogen laboratories within the Institute, where research on a range of traditional foodborne pathogens – Salmonella spp., Campylobacter, Listeria monocytogenes, and Escherichia coli - is undertaken. Her main interest is in developing improved methods to detect the above range of foodborne zoonotic pathogens, principally by generation of novel pathogen-specific binders (antibodies and phage-display derived peptide binders) which are then evaluated for application in magnetic separation, ELISA, lateral flow devices, or other biosensor platforms.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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R1825GFS: Serological detection of Tuberculosis infection using novel phage display-derived peptides
Stewart, L. (PI) & Grant, I. R. (CoI)
16/10/2017 → 30/06/2019
Project: Research
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R6941GFS: Nanodiagnostics for Detection of Foodborne Pathogens using Phage-Derived Proteins
Campbell, K. (PI) & Grant, I. R. (CoI)
01/02/2016 → 04/06/2021
Project: Research
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R1418BSC: IKC in Synthetic Biology
Maggs, C. (PI), Allen, C. C. R. (CoI), Gilmore, B. (CoI), Grant, I. R. (CoI), Hardacre, C. (CoI), Migaud, M. (CoI) & Timson, D. J. (CoI)
08/05/2014 → 30/09/2018
Project: Research
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Cytokine expression in subjects with Mycobacterium avium ssp. paratuberculosis positive blood cultures and a meta-analysis of cytokine expression in Crohn's disease
Kuenstner, J. T., Xu, Q., Bull, T. J., Foddai, A., Grant, I. R., Naser, S., Potula, R., Zhang, P., Shafran, I., Emre Akhanli, S., Khaiboullina, S. & Kruzelock, R., 13 Feb 2024, In: Frontiers in Cellular and Infection Microbiology.Research output: Contribution to journal › Article › peer-review
Open AccessFile27 Downloads (Pure) -
Novel duplex qPCR and LAMP assays Suitable for differentiating Mycobacterium bovis from other Mycobacterium tuberculosis complex species in MGIT sputum cultures
Thomas, M., Gilbride, B., Dane, H., Fairley, D., Johnston, Z. & Grant, I. R., 24 Jun 2024.Research output: Contribution to conference › Poster › peer-review
File9 Downloads (Pure) -
Phytotherapeutic potential against MRSA: mechanisms, synergy, and therapeutic prospects
He, Q., Meneely, J., Grant, I. R., Chin, J., Fanning, S. & Situ, C., 22 Jun 2024, In: Chinese Medicine. 19, 16 p., 89.Research output: Contribution to journal › Article › peer-review
Open AccessFile32 Downloads (Pure) -
Rapid and sensitive detection of viable mycobacteria in bovine faeces and blood by a novel phagomagnetic separation (PhMS)-qPCR assay
Meek, K., Gilbride, B., Dane, H., Thomas, M. & Grant, I. R., 24 Jun 2024.Research output: Contribution to conference › Poster › peer-review
File21 Downloads (Pure) -
Analysis of the Veterinary Risk Assessment and Management Plan questionnaire responses for dairy herds enrolled in the Northern Ireland Johne's disease control programme
Meek, K., Strain, S., O'Connell, N. E. & Grant, I. R., Dec 2023, In: Veterinary Record Open. 10, 2, 11 p., e71.Research output: Contribution to journal › Article › peer-review
Open AccessFile31 Downloads (Pure)
Activities
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Towards serological diagnosis of tuberculosis infection using a combination of in silico and empirical approaches
Stewart, L. (Speaker), Nkongho, F. (Contributor), Grant, I. R. (Contributor) & Bronsvoort, B. M. D. C. (Contributor)
08 Jun 2020Activity: Talk or presentation types › Oral presentation
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Identifying high-risk profile patients for zoonotic tuberculosis in Mubende district, Uganda.
Oleo Popelka, F. (Speaker), Terry, M. (Presenter), Godfrey, E. (Presenter), Muwonge, A. (Presenter), Grant, I. R. (Presenter), Stewart, L. (Presenter), Fujiwara, P. (Presenter) & Kankya, C. (Presenter)
31 Oct 2019Activity: Talk or presentation types › Oral presentation
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External Examiner for PhD thesis
Grant, I. R. (Examiner)
15 Oct 2019 → 15 Nov 2019Activity: Examination types › PhD external examination
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Designing Brochure and Banner for Commercialisation of Product
Stewart, L. (Contributor) & Grant, I. R. (Contributor)
Aug 2019 → Oct 2019Activity: Other activity types › Other
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Zoonotic Tuberculosis: A neglected food safety issue
Stewart, L. (Invited speaker) & Grant, I. R. (Presenter)
Apr 2019Activity: Talk or presentation types › Invited talk