Research output per year
Research output per year
Personal profile
Research Interests
My research interests lie in the field of host-pathogen interactions and how Klebsiella pneumoniae interacts and modulates host immunity.
I am currently investigating how K. pneumoniae uses its type 6 secretion system to alter host immunity (in macrophages, epithelial cells and in vivo) using imaging and biochemical approaches, looking at host immune responses and overall host-microbe interactions.
Teaching
Teaching of the Generic Lab Skills Module on Western Blotting to PhD students in 2015 and 2016.
Mentorship of a master student (October 2015-August 2016).
Mentorship of a summer student as part of the CEM program (July-August 2016).
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Klebsiella pneumoniae emerging anti-immunology paradigms: from stealth to evasion
Sá-Pessoa, J., Calderón-González, R., Lee, A. & Bengoechea, J. A., 30 Jan 2025, (Early online date) In: Trends in Microbiology. 13 p., 2489.Research output: Contribution to journal › Review article › peer-review
Open Access -
In vivo single-cell high-dimensional mass cytometry analysis to track the interactions between Klebsiella pneumoniae and myeloid cells
Calderon-Gonzalez, R., Dumigan, A., Sá-Pessoa, J., Kissenpfennig, A. & Bengoechea, J. A., 05 Apr 2024, In: PLoS Pathogens. 20, 4, 30 p., e1011900.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)28 Downloads (Pure) -
A trans-kingdom T6SS effector induces the fragmentation of the mitochondrial network and activates innate immune receptor NLRX1 to promote infection
Sá-Pessoa, J., López-Montesino, S., Przybyszewska, K., Rodríguez-Escudero, I., Marshall, H., Ova, A., Schroeder, G. N., Barabas, P., Molina, M., Curtis, T., Cid, V. J. & Bengoechea, J. A., 16 Feb 2023, In: Nature Communications. 14, 20 p., 871.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (Scopus)118 Downloads (Pure) -
Modelling the gastrointestinal carriage of Klebsiella pneumoniae infections
Calderon-Gonzalez, R., Lee, A., Lopez-Campos, G., Hancock, S. J., Sa-Pessoa, J., Dumigan, A., McMullan, R., Campbell, E. L. & Bengoechea, J. A., 28 Feb 2023, In: mBio. 14, 1, 19 p., e03121-22.Research output: Contribution to journal › Article › peer-review
Open AccessFile23 Citations (Scopus)123 Downloads (Pure) -
PYHIN protein IFI207 regulates cytokine transcription and IRF7 and contributes to the establishment of K. pneumoniae infection
Baran, M., Feriotti, C., McGinley, A., Carlile, S. R., Jiang, Z., Calderon-Gonzalez, R., Dumigan, A., Sá-Pessoa, J., Sutton, C. E., Kearney, J., McLoughlin, R. M., Mills, K. H. G., Fitzgerald, K. A., Bengeochea, J. A. & Bowie, A. G., 04 Apr 2023, (Early online date) In: Cell Reports. 42, 4, 26 p., 112341.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)68 Downloads (Pure)