John Busby

2025

Clinical remission attainment, definitions, and correlates among patients with severe asthma treated with biologics: a systematic review and meta-analysis

Shackleford, A., Heaney, L. G., Redmond, C., McDowell, P. J. & Busby, J., 03 Jan 2025, In: The Lancet Respiratory Medicine. 13, 1, p. 23-34 12 p.

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3 Citations (Scopus)

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2024

Airway proteomics reveals broad residual anti-inflammatory effects of prednisolone in mepolizumab-treated asthma

Howell, I., Yang, F., Brown, V., Cane, J., Marchi, E., Azim, A., Busby, J., McDowell, P. J., Diver, S. E., Borg, C., Heaney, L. G., Pavord, I. D., Brightling, C. E., Chaudhuri, R. & Hinks, T. S. C., Nov 2024, In: Journal of Allergy and Clinical Immunology. 154, 5, p. 1146-1158

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Analysis of comorbidities and multimorbidity in adult patients in the International Severe Asthma Registry

Scelo, G., Torres-Duque, C. A., Maspero, J. F., Tran, T. N., Murray, R. B., Menzies-Gow, A., Hew, M., Peters, M. J., Gibson, P. G., Christoff, G. C., Popov, T. A., Côté, A., Bergeron, C., Dorscheid, D., FitzGerald, J. M., Chapman, K. R., Boulet, L. P., Bhutani, M., Sadatsafavi, M. & Jiménez-Maldonado, L. & 62 others, Duran-Silva, M., Rodriguez, B., Celis-Preciado, C. A., Cano-Rosales, D. J., Solarte, I., Fernandez-Sanchez, M. J., Parada-Tovar, P., von Bülow, A., Bjerrum, A. S., Suppli Ulrik, C., Assing, K. D., Hansen, S., Altraja, A., Bourdin, A., Taillé, C., Charriot, J., Roche, N., Papaioannou, A. I., Kostikas, K., Papadopoulos, N. G., Salvi, S., Long, D., Mitchell, P., Costello, R. W., Sirena, C., Cardini, C., Heffler, E., Puggioni, F., Canonica, G. W., Guida, G., Iwanaga, T., Al-Ahmad, M., Larenas-Linnemann, D., García, U., Kuna, P., Fonseca, J. A., Al-Lehebi, R., Koh, M. S., Rhee, C. K., Cosio, B. G., Perez de Llano, L., Perng Steve, D.-W., Wan-Chun Huang, E., Tsai, M., Mahboub, B., Salameh, L. I. J., Busby, J., Heaney, L. G., Pfeffer, P. E., Goddard, A. G., Wang, E., Hoyte, F., Wechsler, M. E., Chapman, N., Katial, R., Carter, V., Bulathsinhala, L., Eleangovan, N., Ariti, C., Lyu, J., Price, D. & Porsbjerg, C., Jan 2024, In: Annals of Allergy, Asthma and Immunology. 132, 1, p. 42-53 12 p.

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13 Citations (Scopus)

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Association between pre-biologic T2-Biomaker combinations and response to biologics in patients with severe asthma

Porsbjerg, C. M., Townend, J., Bergeron, C., Christoff, G. C., Katsoulotos, G. P., Larenas-Linnemann, D., Tran, T. N., Al-Lehebi, R., Bosnic-Anticevich, S. Z., Busby, J., Hew, M., Kostikas, K., Papadopoulos, N. G., Pfeffer, P. E., Popov, T. A., Rhee, C. K., Sadatsafavi, M., Tsai, M.-J., Ulrik, C. S. & Al-Ahmad, M. & 30 others, Altraja, A., Beastall, A., Bulathsinhala, L., Carter, V., Cosio, B. G., Fletton, K., Hansen, S., Heaney, L. G., Hubbard, R. B., Kuna, P., Murray, R. B., Nagano, T., Pini, L., Cano Rosales, D. J., Schleich, F., Wechsler, M. E., Amaral, R., Bourdin, A., Brusselle, G. G., Chen, W., Chung, L. P., Denton, E., Fonseca, J. A., Hoyte, F., Jackson, D. J., Katial, R., Kirenga, B. J., Koh, M. S., Ławkiedraj, A. & Lehtimäki, L., 19 Apr 2024, In: Frontiers in Immunology. 15, 21 p., 1361891.

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Association between T2-related comorbidities and effectiveness of biologics in severe asthma

Wechsler, M. E., Scelo, G., Larenas-Linnemann, D. E. S., Torres-Duque, C. A., Maspero, J., Tran, T. N., Murray, R. B., Martin, N., Menzies-Gow, A. N., Hew, M., Peters, M. J., Gibson, P. G., Christoff, G. C., Popov, T. A., Côté, A., Bergeron, C., Dorscheid, D., FitzGerald, J. M., Chapman, K. R. & Boulet, L. P. & 66 others, Bhutani, M., Sadatsafavi, M., Jiménez-Maldonado, L., Duran-Silva, M., Rodriguez, B., Celis-Preciado, C. A., Cano-Rosales, D. J., Solarte, I., Fernandez-Sanchez, M. J., Parada-Tovar, P., von Bülow, A., Bjerrum, A. S., Ulrik, C. S., Assing, K. D., Rasmussen, L. M., Hansen, S., Altraja, A., Bourdin, A., Taille, C., Charriot, J., Roche, N., Papaioannou, A. I., Kostikas, K., Papadopoulos, N. G., Salvi, S., Long, D., Mitchell, P. D., Costello, R., Sirena, C., Cardini, C., Heffler, E., Puggioni, F., Canonica, G. W., Guida, G., Iwanaga, T., Al-Ahmad, M., García, U., Kuna, P., Fonseca, J. A., Al-Lehebi, R., Koh, M. S., Rhee, C. K., Cosio, B. G., Perez de Llano, L., Perng, D. W. S., Huang, E. W. C., Wang, H. C., Tsai, M. J., Mahboub, B., Salameh, L. I. J., Jackson, D. J., Busby, J., Heaney, L. G., Pfeffer, P. E., Goddard, A. G., Wang, E., Hoyte, F. C. L., Chapman, N. M., Katial, R., Carter, V., Bulathsinhala, L., Eleangovan, N., Ariti, C., Lyu, J., Porsbjerg, C. & Price, D. B., 01 Feb 2024, In: American Journal of Respiratory and Critical Care Medicine. 209, 3, p. 262-272 11 p.

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12 Citations (Scopus)

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Clinical and economic burden of severe asthma with low blood eosinophil counts

Busby, J., Menon, S., Martin, N., Lipworth, J., Zhang, R., Burhan, H., Brown, T., Chaudhuri, R., Gore, R., Jackson, D. J., Naveed, S., Pantin, T., Pfeffer, P. E., Patel, M., Patel, P. H., Rupani, H. & Heaney, L. G., 07 Oct 2024, In: The Journal of Allergy and Clinical Immunology: In Practice. 12, 10, p. 2785-2797 13 p.

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Ethnic variation in asthma phenotypic presentation and outcomes: a cross-sectional analysis of the UK biobank

Busby, J., McDowell, P. J., Pfeffer, P. E., Mansur, A. H. & Heaney, L. G., Feb 2024, In: Thorax. 79 , 2, p. 186-190

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Exploring definitions and predictors of response to biologics for severe asthma

Scelo, G., Tran, T. N., Le, T. T., Faregås, M., Dorscheid, D., Busby, J., Al-Ahmad, M., Al-Lehebi, R., Altraja, A., Beastall, A., Bergeron, C., Bjermer, L., Bjerrum, A. S., Cano-Rosales, D. J., Canonica, G. W., Carter, V., Charriot, J., Christoff, G. C., Cosio, B. G. & Denton, E. & 35 others, Fernandez-Sanchez, M. J., Fonseca, J. A., Gibson, P. G., Goh, C., Heaney, L. G., Heffler, E., Hew, M., Iwanaga, T., Katial, R., Koh, M. S., Kuna, P., Larenas-Linnemann, D., Lehtimäki, L., Mahboub, B., Martin, N., Matsumoto, H., Menzies-Gow, A. N., Papadopoulos, N. G., Patel, P., Perez-De-Llano, L., Peters, M., Pfeffer, P. E., Popov, T. A., Porsbjerg, C. M., Rhee, C. K., Sadatsafavi, M., Taillé, C., Torres-Duque, C. A., Tsai, M.-J., Ulrik, C. S., Upham, J. W., von Bülow, A., Wang, E., Wechsler, M. E. & Price, D. B., 05 Sept 2024, In: Journal of Allergy and Clinical Immunology: In Practice. 12, 9, p. 2347-2361

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4 Citations (Scopus)

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Exploring definitions and predictors of severe asthma clinical remission post-biologic in adults

Perez-de-Llano, L., Scelo, G., Tran, T. N., Le, T. T., Fagerås, M., Cosio, B. G., Peters, M., Pfeffer, P. E., Al-Ahmad, M., Al-Lehebi, R. O., Altraja, A., Bergeron, C., Bjermer, L. H., Bjerrum, A. S., Bulathsinhala, L., Busby, J., Cano Rosales, D. J., Canonica, G. W., Carter, V. A. & Charriot, J. & 35 others, Christoff, G. C., Denton, E. J., Dorscheid, D. R., Fernandez Sanchez, M. J., Fonseca, J. A., Gibson, P. G., Goh, C. Y. Y., Heaney, L. G., Heffler, E., Hew, M., Iwanaga, T., Katial, R., Koh, M. S., Kuna, P., Larenas-Linnemann, D. E. S., Lehtimäki, L., Mahboub, B., Martin, N., Matsumoto, H., Menzies-Gow, A. N., Papadopoulos, N. G., Popov, T. A., Porsbjerg, C. M., Patel, P., Rhee, C. K., Sadatsafavi, M., Taillé, C., Torres-Duque, C. A., Tsai, M.-J., Ulrik, C. S., Upham, J. W., von Bülow, A., Wang, E., Wechsler, M. E. & Price, D. B., 01 Oct 2024, In: American Journal of Respiratory and Critical Care Medicine. 210, 7, p. 869-880

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18 Citations (Scopus)

Exploring the carbon footprint of severe asthma and change after biologic therapy initiation: an analysis of Northern Irish data

Busby, J., Khezrian, M., Patel, S., Tran, T. N., Rhodes, K. & Heaney, L. G., 12 Dec 2024, (Early online date) In: ERJ Open Research.

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Impact of comorbidities on EQ-5D quality-of-life index in severe asthma

Pfeffer, P. E., Brown, T., Chaudhuri, R., Faruqi, S., Gore, R., Heaney, L. G., Mansur, A. H., Pantin, T., Patel, M., Rupani, H., Siddiqui, S., Vyas, A. & Busby, J., Aug 2024, In: Journal of Allergy and Clinical Immunology: Global. 3, 3, 10 p., 100286.

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Impact of pre-biologic impairment on meeting domain-specific biologic responder definitions in patients with severe asthma

Perez-de-Llano, L., Scelo, G., Canonica, G. W., Chen, W., Henley, W., Larenas-Linnemann, D., Peters, M. J., Pfeffer, P. E., Tran, T. N., Ulrik, C. S., Popov, T. A., Sadatsafavi, M., Hew, M., Maspero, J., Gibson, P. G., Christoff, G. C., Fitzgerald, J. M., Torres-Duque, C. A., Porsbjerg, C. M. & Papadopoulos, N. G. & 29 others, Papaioannou, A. I., Heffler, E., Iwanaga, T., Al-Ahmad, M., Kuna, P., Fonseca, J. A., Al-Lehebi, R., Rhee, C. K., Koh, M. S., Cosio, B. G., Perng Steve, D.-W., Mahboub, B., Menzies-Gow, A. N., Jackson, D. J., Busby, J., Heaney, L. G., Patel, P. H., Wang, E., Wechsler, M. E., Altraja, A., Lehtimäki, L., Bourdin, A., Bjermer, L., Bulathsinhala, L., Carter, V., Murray, R., Beastall, A., Denton, E. & Price, D. B., 01 May 2024, In: Annals of Allergy, Asthma and Immunology. 132, 5, p. 610-622.e7

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2 Citations (Scopus)

7 Downloads (Pure)

Impact of sex on severe asthma: a cross-sectional retrospective analysis of UK primary and specialist care

Loewenthal, L., Busby, J., McDowell, R., Brown, T., Burhan, H., Chaudhuri, R., Dennison, P., Dodd, J. W., Doe, S., Faruqi, S., Gore, R., Idris, E., Jackson, D. J., Patel, M., Pantin, T., Pavord, I., Pfeffer, P. E., Price, D. B., Rupani, H. & Siddiqui, S. & 2 others, Heaney, L. G. & Menzies-Gow, A., May 2024, In: Thorax. 79, 5, p. 403-411 9 p.

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5 Citations (Scopus)

128 Downloads (Pure)

International variation in severe exacerbation rates in patients with severe asthma

Lee, T. Y., Price, D., Yadav, C. P., Roy, R., Huey Mien, L. L., Wang, E., Wechsler, M. E., Jackson, D. J., Busby, J., Heaney, L. G., Pfeffer, P. E., Mahboub, B., Perng Steve, D.-W., Cosio, B. G., Perez-de-Llano, L., Al-Lehebi, R., Larenas-Linnemann, D., Al-Ahmad, M., Rhee, C. K. & Iwanaga, T. & 18 others, Heffler, E., Canonica, G. W., Costello, R., Papadopoulos, N. G., Papaioannou, A. I., Porsbjerg, C. M., Torres-Duque, C. A., Christoff, G. C., Popov, T. A., Hew, M., Peters, M., Gibson, P. G., Maspero, J., Bergeron, C., Cerda, S., Contreras Contreras, E. A., Chen, W. & Sadatsafavi, M., Jul 2024, In: Chest. 166, 1, p. 28-38

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3 Citations (Scopus)

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Longitudinal assessment of glucocorticoid toxicity reduction in patients with severe asthma treated with biologic therapies

McDowell, P. J., Busby, J., Stone, J. H., Butler, C. A. & Heaney, L. G., 29 Oct 2024, (Early online date) In: The Journal of Allergy and Clinical Immunology: In Practice.

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Oral prednisolone and warfarin and risk of oesophageal cancer: a case-control study

Cardwell, C. R., McDowell, R. D., Hughes, C. M., Busby, J. & Murchie, P., Jun 2024, In: Cancer Epidemiology. 90, 7 p., 102552.

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Pharmacoequity in allergy-immunology: disparities in access to medications for allergic diseases and proposed solutions in the US and globally

Maldonado-Puebla, M., Akenroye, A., Busby, J., Cardet, J. C. & Louisias, M., Feb 2024, In: Journal of Allergy and Clinical Immunology: In Practice. 12, 2, p. 272-280 9 p.

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3 Citations (Scopus)

Real‐world biologics response and super‐response in the International Severe Asthma Registry cohort

Denton, E., Hew, M., Peters, M. J., Upham, J. W., Bulathsinhala, L., Tran, T. N., Martin, N., Bergeron, C., Al‐Ahmad, M., Altraja, A., Larenas‐Linnemann, D., Murray, R., Celis‐Preciado, C. A., Al‐Lehebi, R., Belhassen, M., Bhutani, M., Bosnic‐Anticevich, S. Z., Bourdin, A., Brusselle, G. G. & Busby, J. & 31 others, Canonica, G. W., Heffler, E., Chapman, K. R., Charriot, J., Christoff, G. C., Chung, L. P., Cosio, B. G., Côté, A., Costello, R. W., Cushen, B., Fingleton, J., Fonseca, J. A., Gibson, P. G., Heaney, L. G., Huang, E. W., Iwanaga, T., Jackson, D. J., Koh, M. S., Lehtimäki, L., Máspero, J., Mahboub, B., Menzies‐Gow, A. N., Mitchell, P. D., Papadopoulos, N. G., Papaioannou, A. I., Perez‐de‐Llano, L., Perng, D., Pfeffer, P. E., Popov, T. A., Porsbjerg, C. M. & the ISAR LUMINANT Working Group, 22 Jun 2024, (Early online date) In: Allergy.

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2 Citations (Scopus)

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2023

Adult severe asthma registries: a global and growing inventory

Cushen, B., Koh, M., Tran, T., Martin, N., Murray, R., Uthaman, T., Goh, C., Vella, R., Eleangovan, N., Bulathsinhala, L., Maspero, J., Peters, M., Schleich, F., Pitrez, P., Christoff, G., Sadatsafavi, M., Torres-Duque, C., Porsbjerg, C., Altraja, A. & Lehtimäki, L. & 24 others, Bourdin, A., Taube, C., Papadopoulos, N., Zsuzsanna, C., Björnsdóttir, U., Salvi, S., Heffler, E., Iwanaga, T., al-Ahmad, M., Larenas-Linnemann, D., van Boven, J., Aarli, B., Kuna, P., Loureiro, C., Al-lehebi, R., Lee, J., Marina, N., Bjermer, L., Sheu, C., Mahboub, B., J, B., Menzies-Gow, A., Wang, E. & Price, D., 20 Oct 2023, In: Pragmatic and observational research. 14, p. 127–147

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An examination of factorial invariance of the Asthma Control Questionnaire among adults with severe asthma

McDowell, R., Heaney, L., Brown, T., Bunting, B., Burhan, H., Chaudhuri, R., Dennison, P., Faruqi, S., Gore, R., Jackson, D. J., Menzies-Gow, A., Pantin, T., Patel, M., Pfeffer, P., Siddiqui, S., Busby, J. & on behalf of the UK Severe Asthma Registry, 07 Dec 2023, In: PLoS One. 18, 12, 17 p., e0295493.

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1 Citation (Scopus)

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A randomized trial of a composite T2-biomarker strategy adjusting corticosteroid treatment in severe asthma: a post- hoc analysis by sex

Eastwood, M. C., Busby, J., Jackson, D. J., Pavord, I. D., Hanratty, C. E., Djukanovic, R., Woodcock, A., Walker, S., Hardman, T. C., Arron, J. R., Choy, D. F., Bradding, P., Brightling, C. E., Chaudhuri, R., Cowan, D., Mansur, A. H., Fowler, S. J., Howarth, P., Lordan, J. & Menzies-Gow, A. & 6 others, Harrison, T., Robinson, D. S., Holweg, C. T. J., Matthews, J. G., Heaney, L. G. & RASPUK Investigators, Apr 2023, In: The Journal of Allergy and Clinical Immunology: In Practice. 11, 4, p. 1233-1242.e5 15 p.

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13 Citations (Scopus)

54 Downloads (Pure)

Asthma exacerbations in severe asthma: why systemic corticosteroids may not always be the best treatment option

McDowell, P. J., Busby, J. & Heaney, L. G., 25 Feb 2023, (Early online date) In: Current Treatment Options in Allergy. 11 p.

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2 Citations (Scopus)

55 Downloads (Pure)

Blood transcriptomic signature in type-2 biomarker-low severe asthma and asthma control

Zeng, X., Qing, J., Yamawaki, T., Hsu, Y.-H., Vander Lugt, B., Hsu, H., Busby, J., McDowell, P. J., Jackson, D. J., Djukanovic, R., Matthews, J. G., Aaron, J. R., Bradding, P., Brightling, C. E., Chaudhuri, R., Choy, D. F., Fowler, S., Hardman, T. C., Howarth, P. & Mansur, A. & 5 others, AN, M.-G., Pavord, I., Walker, S., Woodcock, A. & Heaney, L., Oct 2023, In: Journal of Allergy and Clinical Immunology. 152, 4, p. 876-886 11 p.

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Clinical remission in severe asthma with biologic therapy: an analysis from the UK Severe Asthma Registry

McDowell, P. J., McDowell, R., Busby, J., Eastwood, M. C., Patel, P. H., Jackson, D. J., Mansur, A., Patel, M., Burhan, H., Doe, S., Chaudhuri, R., Gore, R., Dodd, J. W., Subramanian, D., Brown, T. & Heaney, L. G., 01 Dec 2023, In: European Respiratory Journal. 62, 6, 12 p., 2300819.

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46 Citations (Scopus)

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Comparative effectiveness of Anti-IL5 and Anti-IgE biologic classes in patients with severe asthma eligible for both

Pfeffer, P. E., Ali, N., Murray, R., Ulrik, C., Tran, T. N., Maspero, J., Peters, M., Christoff, G. C., Sadatsafavi, M., Torres-Duque, C. A., Altraja, A., Lehtimäki, L., Papadopoulos, N. G., Salvi, S., Costello, R. W., Cushen, B., Heffler, E., Iwanaga, T., Al-Ahmad, M. & Larenas-Linnemann, D. & 49 others, Kuna, P., Fonseca, J. A., Al-Lehebi, R., Rhee, C. K., Perez-de-Llano, L., Perng Steve, D.-W., Mahboub, B., Wang, E., Goh, C., Lyu, J., Newell, A., Alacqua, M., Belevskiy, A. S., Bhutani, M., Bjermer, L., Bjornsdottir, U., Bourdin, A., von Bulow, A., Busby, J., Canonica, G. W., Cosio, B. G., Dorscheid, D., Muñoz-Esquerre, M., FitzGerald, J. M., Gil, E. G., Gibson, P. G., Heaney, L. G., Hew, M., Hilberg, O., Hoyte, F., Jackson, D. J., Koh, M. S., Ko Bruce, H.-K., Lee, J. H., Lehmann, S., Chaves Loureiro, C., Lúðvíksdóttir, D., Menzies-Gow, A. N., Mitchell, P., Papaioannou, A. I., Popov, T. A., Porsbjerg, C. M., Salameh, L., Sirena, C., Taillé, C., Taube, C., Tohda, Y., Wechsler, M. E. & Price, D., 17 Mar 2023, (Early online date) In: Allergy.

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11 Citations (Scopus)

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Difficult-to-treat asthma patients from ethnic minority groups in central England are at an enhanced risk of house dust mite sensitisation

Mansur, A. H., Marsh, J., Bahron, A., Thomas, M., Walters, G., Busby, J., Heaney, L. G. & Krishna, M. T., 08 Oct 2023, In: Clinical and Translational Allergy. 13, 10, 12 p., e12303.

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Ethnic variation in asthma healthcare utilisation and exacerbation: systematic review and meta-analysis

Akin-Imran, A. Q., Bajpai, A., McCartan, D., Heaney, L. G., Kee, F., Redmond, C. & Busby, J., 01 May 2023, In: ERJ Open Research. 9, 3, 15 p., 00591-2022.

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4 Citations (Scopus)

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Impact of initiatinG bioLogics In patients with severe asThma on long-Term OCS or frEquent Rescue steroids (GLITTER): data from the International Severe Asthma Registry

Chen, W., Tran, T. N., Sadatsafavi, M., Murray, R., Wong, N. C. B., Ali, N., Ariti, C., Bulathsinhala, L., Gil, E. G., FitzGerald, J. M., Alacqua, M., Al-Ahmad, M., Altraja, A., Al-Lehebi, R., Bhutani, M., Bjermer, L., Bjerrum, A.-S., Bourdin, A., von Bülow, A. & Busby, J. & 44 others, Walter Canonica, G., Carter, V., Christoff, G. C., Cosio, B. G., Costello, R. W., Fonseca, J. A., Gibson, P. G., Yoo, K.-H., Heaney, L. G., Heffler, E., Hew, M., Hilberg, O., Hoyte, F., Iwanaga, T., Jones, R. C., Koh, M. S., Kuna, P., Larenas-Linnemann, D., Lehmann, S., Lehtimäki, L., Lyu, J., Mahboub, B., Maspero, J., Menzies-Gow, A. N., Newell, A., Sirena, C., Papadopoulos, N. G., Papaioannou, A. I., Perez-de-Llano, L., Perng Steve, D.-W., Peters, M., Pfeffer, P. E., Porsbjerg, C. M., Popov, T. A., Rhee, C. K., Salvi, S., Taillé, C., Taube, C., Torres-Duque, C. A., Ulrik, C., Ra, S.-W., Wang, E., Wechsler, M. E. & Price, D. B., 08 Jun 2023, (Early online date) In: Journal of Allergy and Clinical Immunology: In Practice.

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Investigating the impact of a 20 miles per hour speed limit intervention on road traffic collisions, casualties, speed and volume in Belfast, UK: 3 year follow-up outcomes of a natural experiment

Hunter, R. F., Cleland, C. L., Busby, J., Nightingale, G., Kee, F., Williams, A. J., Kelly, P., Kelly, M. P., Milton, K., Kokka, K. & Jepson, R., Jan 2023, In: Journal of Epidemiology & Community Health. 77, 1, p. 17–25 9 p.

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3 Citations (Scopus)

81 Downloads (Pure)

Multiorgan MRI findings after hospitalisation with COVID-19 in the UK (C-MORE): a prospective, multicentre, observational cohort study

Brown, J., Jones, M. G., Davies, M. J., Rowland, M. J., Scott, J. T., Heaney, L. G., Hughes, P. J. C., Smith, S., Baillie, J. K., Walker, S., Armour, C., McGarvey, L., Magee, N., Drain, S., Craig, T., Watson, L., Robertson, E., McCormick, W., Martinez, L. M. & Owen, J. & 88 others, Mills, C., Wright, C., Russell, E., Johnston, D., Mitchell, J., Price, L., Walsh, S., McMahon, A., Byrne, S., Dobson, S. L., McIvor, K., Hanley, N. A., Young, A., Price, D., Burns, G., Simpson, J., Wright, S., McMahon, M. J., Anderson, D., Grieve, D., McInnes, I. B., George, J., Mohammed, S., Chen, J., Pavlides, M., Burns, A., Connolly, B., Busby, J., Peto, T., Nolan, C. M., Walsh, J. A., Barker, R. E., Johnson, C., Milner, L., Begum, M., Marshall, M., McNeill, J., Banerjee, A., Xu, M., Bell, R., Chambers, R. C., Casey, A., Cooper, B., Wilson, D., Marshall, B., Harvey, M., Fletcher, S., Mills, G., Armstrong, N., Cairns, P., McCourt, P., Siddiqui, S., Ward, T. J. C., Mcnally, T., Wilkinson, D., Walmsley, S., O'Donnell, K., Sharma, M., McArdle, A., Khan, F., Stewart, I., Wright, L., Johnson, S., Fu, X., Li, X., Carson, G., Robinson, E., Cooper, J., Elliott, K., Brown, V., Brown, M., Brown, J., Jones, S., Jones, H., Jones, L., Howard, K., Scott, K., Thomas, S., Lewis, J., Hughes, A. D., Thompson, T., Kelly, S., Smith, D., Smith, S., Evans, D., Evans, R., Evans, J. & The C-MORE/PHOSP-COVID Collaborative Group, 01 Nov 2023, In: The Lancet Respiratory Medicine. 11, 11, p. 1003-1019 17 p.

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28 Citations (Scopus)

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Prevalence of physical frailty, including risk factors, up to 1 year after hospitalisation for COVID-19 in the UK: a multicentre, longitudinal cohort study

McAuley, H. J. C., Evans, R. A., Bolton, C. E., Brightling, C. E., Chalmers, J. D., Docherty, A. B., Elneima, O., Greenhaff, P. L., Gupta, A., Harris, V. C., Harrison, E. M., Ho, L.-P., Horsley, A., Houchen-Wolloff, L., Jolley, C. J., Leavy, O. C., Lone, N. I., Man, W.D.-C., Marks, M. & Parekh, D. & 37 others, Poinasamy, K., Quint, J. K., Raman, B., Richardson, M., Saunders, R. M., Sereno, M., Shikotra, A., Singapuri, A., Singh, S. J., Steiner, M., Tan, A. L., Wain, L. V., Welch, C., Whitney, J., Witham, M. D., Lord, J., Greening, N. J., PHOSP-COVID Study Collaborative Group, Armour, C., Busby, J., Connolly, B., Drain, S., Grieve, D., Hart, N., Harvey, M., Heaney, L. G., Hughes, J., Jones, M. G., Magee, N., McArdle, A., McGarvey, L., Mills, C., Mitchell, J., Peto, T., Rowland, M., Sharma, M. & Siddiqui, S., 11 Mar 2023, In: eClinicalMedicine. 57, 101896.

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13 Citations (Scopus)

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SARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination

Liew, F., Talwar, S., Cross, A., Willett, B. J., Scott, S., Logan, N., Siggins, M. K., Swieboda, D., Sidhu, J. K., Efstathiou, C., Moore, S. C., Davis, C., Mohamed, N., Nunag, J., King, C., Thompson, A. A. R., Rowland-Jones, S. L., Docherty, A. B., Chalmers, J. D. & Ho, L.-P. & 44 others, Horsley, A., Raman, B., Poinasamy, K., Marks, M., Kon, O. M., Howard, L., Wootton, D. G., Dunachie, S., Quint, J. K., Evans, R. A., Wain, L. V., Fontanella, S., de Silva, T. I., Ho, A., Harrison, E., Baillie, J. K., Semple, M. G., Brightling, C., Thwaites, R. S., Turtle, L., Openshaw, P. J. M., ISARIC4C Investigators, Armour, C., Carson, G., Busby, J., Connolly, B., Cooper, J., Drain, S., Grieve, D., Hart, N., Harvey, M., Heaney, L. G., Hughes, J., Jones, M. G., Magee, N., McArdle, A., McGarvey, L., Mills, C., Mitchell, J., Peto, T., Powell, N., Rowland, M., Sharma, M. & Siddiqui, S., 16 Jan 2023, In: EBioMedicine. 87, 104402.

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71 Citations (Scopus)

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Unsupervised home spirometry versus supervised clinic spirometry for respiratory disease: a systematic methodology review and meta-analysis

Anand, R., McLeese, R., Busby, J., Stewart, J., Clarke, M., Man, W.D.-C. & Bradley, J., 30 Sept 2023, In: European Respiratory Review. 32, 169, 13 p., 220248.

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8 Citations (Scopus)

56 Downloads (Pure)

2022

Benefits of specialist severe asthma management: demographic and geographic disparities

Redmond, C., Heaney, L. G., Chaudhuri, R., Jackson, D. J., Menzies-Gow, A., Pfeffer, P. & Busby, J., 01 Dec 2022, In: European Respiratory Journal. 60, 6, 10 p., 2200660.

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18 Citations (Scopus)

16 Downloads (Pure)

Biologic therapy practices in severe asthma; outcomes from the UK Severe Asthma Registry and survey of specialist opinion

Mansur, A. H., Gonem, S., Brown, T., Burhan, H., Chaudhuri, R., Dodd, J. W., Pantin, T., Gore, R., Jackson, D., Menzies-Gow, A., Patel, M., Pavord, I., Pfeffer, P., Siddiqui, S., Busby, J. & Heaney, L. G., 03 Sept 2022, (Early online date) In: Clinical & Experimental Allergy.

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9 Citations (Scopus)

116 Downloads (Pure)

Characterization of patients in the international severe asthma registry with high steroid exposure who did or did not initiate biologic therapy

Chen, W., Sadatsafavi, M., Tran, T. N., Murray, R. B., Wong, C. B. N., Ali, N., Ariti, C., Garcia Gil, E., Newell, A., Alacqua, M., Al-Ahmad, M., Altraja, A., Al-Lehebi, R., Bhutani, M., Bjermer, L., Bjerrum, A. S., Bourdin, A., Bulathsinhala, L., von Bülow, A. & Busby, J. & 30 others, Canonica, G. W., Carter, V., Christoff, G. C., Cosio, B. G., Costello, R. W., FitzGerald, J. M., Fonseca, J. A., Yoo, K. H., Heaney, L. G., Heffler, E., Hew, M., Hilberg, O., Hoyte, F., Iwanaga, T., Jackson, D. J., Jones, R. C., Koh, M. S., Kuna, P., Larenas-Linnemann, D., Lehmann, S., Lehtimäki, L. A., Lyu, J., Mahboub, B., Maspero, J., Menzies-Gow, A. N., Sirena, C., Papadopoulos, N., Papaioannou, A. I., Pérez de Llano, L. & Perng, D.-W., 21 Oct 2022, In: Journal of Asthma and Allergy. 15, p. 1491-1510

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11 Citations (Scopus)

20 Downloads (Pure)

Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study

Evans, R. A., Richardson, M., Brown, J. S., Hart, N., Jones, M. G., Rahman, N. M., Shah, A. M., Davies, M. J., Geddes, J. R., Heaney, L. G., Jenkins, R. G., McCann, G. P., Porter, J. C., Rowland, M. J., Scott, J. T., Semple, M. G., Singh, S. J., Kerr, S., Ahmad, S. & Ali, M. & 179 others, Armour, C., Baillie, J. K., Banerjee, A., Barker, R. E., Begum, M., Bell, D., Bell, R., Bennett, K., Bingham, M., Bourne, M., Brown, A., Brown, J. S., Brown, M., Brown, V., Burns, G., Burns, A., Busby, J., Butt, A., Byrne, S., Cairns, P., Carr, C., Carson, G., Casey, A., Chambers, R. C., Chapman, K., Chen, J., Cheng, Y., Clarke, J., Cole, J., Connolly, B., Cooper, B., Cooper, J., Cooper, S., Craig, T., Cross, A., Daly, P., Davies, G., Davies, G., Dobson, S. L., Drain, S., Edwards, S., Elliott, A., Elliott, K., Evans, D., Evans, J., Evans, R. A., Evans, R. A., Fletcher, S., Flynn, M., Ford, A., Francis, S., Fu, X., George, J., Glover, S., Goodwin, C., Greenwood, J., Grieve, D., Griffin, D., Gupta, A., Hall, L., Hanley, N. A., Harrington, K., Harris, E., Harvey, A., Harvey, M., Hewitt, M., Holloway, L., Howard, K., Hughes, A. D., Hughes, J., Hughes, R., Hutchinson, J., Johnson, C., Johnson, S., Johnston, D., Jones, D., Jones, H., Jones, L., Jones, S., Kelly, S., Khan, F., Kilroy, S., King, B., Kirk, J., Lee, J. H., Lewis, J., Li, X., Lynch, C., Magee, N., Marshall, B., Marshall, M., Martin, J., Matthews, L., McArdle, A., McCormick, J., McCormick, W., McCourt, P., McGarvey, L., McInnes, I. B., McIntosh, J., McIvor, K., McMahon, A., McMahon, M. J., Mcnally, T., McNeill, J., Miller, C., Mills, C., Milner, L., Mitchell, J., Mohamed, A., Mohammed, S., Morrison, L., Newman, T., Nolan, C. M., O'Donnell, K., O'Brien, C., O'Brien, L., Owen, J., Palmer, S., Pavlides, M., Peng, Y., Peto, T., Porter, J. C., Powell, N., Pratt, J., Price, A., Price, D., Price, L., Reed, A., Robertson, E., Robinson, E., Robinson, L., Ross, A., Ross, G., Roy, M., Russell, E., Scott, K., Sewell, T. A., Sharma, M., Shaw, A., Siddiqui, S., Simpson, J., Simpson, N., Singh, S. J., Smith, A., Smith, D., Smith, S., Smith, J., Smith, L., Stewart, I., Taylor, A., Taylor, C., Taylor, J., Thomas, C., Thomas, S., Thompson, T., Thompson, A. A. R., Turner, S., Walker, S., Walsh, J. A., Walsh, S., Ward, T. J. C., Watson, E., Watson, L., Watson, J., White, S., Wilkinson, D., Williams, J., Wilson, A., Wilson, D., Wilson, I., Woods, J., Wright, C., Wright, L., Wright, S., Xu, M., Young, S., Young, A. & PHOSP-COVID Study Collaborative Group, 01 Aug 2022, In: The Lancet Respiratory Medicine. 10, 8, p. 761-775 15 p.

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245 Citations (Scopus)

33 Downloads (Pure)

Corticosteroid responsiveness following mepolizumab in severe eosinophilic asthma - a randomised, placebo-controlled crossover trial (MAPLE)

Yang, F., Busby, J., Heaney, L. G., Pavord, I., Brightling, C., Borg, K., McDowell, P. J., Diver, S. E., Shrimanker, R., Bradding, P., Shepherd, M. & Chaudhuri, R., 18 Jul 2022, (Early online date) In: The Journal of Allergy and Clinical Immunology: In Practice.

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8 Citations (Scopus)

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Ethnic Differences in Severe Asthma Clinical Care and Outcomes: An Analysis of United Kingdom Primary and Specialist Care

Busby, J., Heaney, L., Brown, T., Chaudhuri, R., Dennison, P., Gore, R., Jackson, D. J., Mansur, A. H., Menzies-Gow, A. N., Message, S., Niven, R., Patel, M., Price, D., Siddiqui, S., Stone, R. & Pfeffer, P., 01 Feb 2022, In: The Journal of Allergy and Clinical Immunology: In Practice. 10, 2, p. 495-505 11 p.

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16 Citations (Scopus)

305 Downloads (Pure)

Exacerbation Profile and Risk Factors in a T2-Low Severe Asthma Population

McDowell, P. J., Busby, J., Hanratty, C. E., Djukanovic, R., Woodcock, A., Walker, S., Hardman, T. C., Arron, J. R., Choy, D. F., Bradding, P., Brightling, C. E., Chaudhuri, R., Cowan, D., Mansur, A. H., Fowler, S. J., Diver, S. E., Howarth, P., Lordan, J., Menzies-Gow, A. & Harrison, T. & 5 others, Robinson, D. S., Holweg, C. T. J., Matthews, J. G., Pavord, I. D. & Heaney, L. G., 12 May 2022, (Early online date) In: American Journal of Respiratory and Critical Care Medicine.

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19 Citations (Scopus)

65 Downloads (Pure)

Factors affecting adherence with treatment advice in a clinical trial of patients with severe asthma

Busby, J., Matthews, J. G., Chaudhuri, R., Pavord, I. D., Hardman, T. C., Arron, J. R., Bradding, P., Brightling, C. E., Choy, D. F., Cowan, D. C., Djukanovic, R., Hanratty, C. E., Harrison, T. W., Holweg, C. T., Howarth, P. H., Fowler, S. J., Lordan, J. L., Mansur, A. H., Menzies-Gow, A. & Niven, R. M. & 4 others, Robinson, D. S., Walker, S. M., Woodcock, A. & Heaney, L. G., 28 Apr 2022, In: European Respiratory Journal. 59, 4, 2100768.

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10 Citations (Scopus)

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Global Variability in Administrative Approval Prescription Criteria for Biologic Therapy in Severe Asthma

Porsbjerg, C. M., Menzies-Gow, A. N., Tran, T. N., Murray, R. B., Unni, B., Audrey Ang, S. L., Alacqua, M., Al-Ahmad, M., Al-Lehebi, R., Altraja, A., Belevskiy, A. S., Björnsdóttir, U. S., Bourdin, A., Busby, J., Canonica, G. W., Christoff, G. C., Cosio, B. G., Costello, R. W., FitzGerald, J. M. & Fonseca, J. A. & 39 others, Hansen, S., Heaney, L. G., Heffler, E., Hew, M., Iwanaga, T., Jackson, D. J., Kocks, J. W. H., Kallieri, M., Bruce Ko, H.-K., Koh, M. S., Larenas-Linnemann, D., Lehtimäki, L. A., Loukides, S., Lugogo, N., Maspero, J., Papaioannou, A. I., Perez-de-Llano, L., Pitrez, P. M., Popov, T. A., Rasmussen, L. M., Rhee, C. K., Sadatsafavi, M., Schmid, J., Siddiqui, S., Taillé, C., Taube, C., Torres-Duque, C. A., Ulrik, C., Upham, J. W., Wang, E., Wechsler, M. E., Bulathsinhala, L., Carter, V., Chaudhry, I., Eleangovan, N., Hosseini, N., Rowlands, M.-A., Price, D. & van Boven, J. F., 05 May 2022, In: The Journal of Allergy and Clinical Immunology: In Practice. 10, 5, p. 1202-1216.e23

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34 Citations (Scopus)

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Real World Biologic Use and Switch Patterns in Severe Asthma: Data from the International Severe Asthma Registry and the US CHRONICLE Study

Menzies-Gow, A., McBrien, C., Unni, B., Porsbjerg, C., Al-Ahmad, M., Ambrose, C., Dahl Assing, K., von Bülow, A., Busby, J., Cosio, B., FitzGerald, J., Garcia Gil, E., Hansen, S., Heaney, L. G., Hew, M., Jackson, D., Kallieri, M., Loukides, S., Lugogo, N. & Papaioannou, A. & 18 others, Larenas-Linnemann, D., Moore, W., Perez-de-Llano, L., Rasmussen, L., Schmid, J., Siddiqui, S., Alacqua, M., Tran, T., Suppli Ulrik, C., Upham, J., Wang, E., Bulathsinhala, L., Carter, V., Chaudhry, I., Eleangovan, N., Murray, R., Price, C. & Price, D., 13 Jan 2022, In: Journal of Asthma and Allergy. 15, p. 63-78 16 p.

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55 Citations (Scopus)

49 Downloads (Pure)

Relationship between inflammatory status and microbial composition in severe asthma and during exacerbation

Diver, S., Haldar, K., McDowell, P. J., Busby, J., Mistry, V., Micieli, C., Brown, V., Cox, C., Yang, F., Borg, C., Shrimanker, R., Ramsheh, M. Y., Hardman, T. C., Arron, J. R., Bradding, P., Cowan, D., Mansur, A. H., Fowler, S. J., Lordan, J. & Menzies-Gow, A. & 7 others, Robinson, D. S., Matthews, J. G., Pavord, I. D., Chaudhuri, R., Heaney, L. G., Barer, M. R. & Brightling, C. E., 01 Jul 2022, (Early online date) In: Allergy.

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14 Citations (Scopus)

49 Downloads (Pure)

2021

Eosinophilic and Noneosinophilic Asthma: An Expert Consensus Framework to Characterize Phenotypes in a Global Real-Life Severe Asthma Cohort

Heaney, L. G., Perez de Llano, L., Al-Ahmad, M., Backer, V., Busby, J., Canonica, G. W., Christoff, G. C., Cosio, B. G., FitzGerald, J. M., Heffler, E., Iwanaga, T., Jackson, D. J., Menzies-Gow, A. N., Papadopoulos, N. G., Papaioannou, A. I., Pfeffer, P. E., Popov, T. A., Porsbjerg, C. M., Rhee, C. K. & Sadatsafavi, M. & 29 others, Tohda, Y., Wang, E., Wechsler, M. E., Alacqua, M., Altraja, A., Bjermer, L., Björnsdóttir, U. S., Bourdin, A., Brusselle, G. G., Buhl, R., Costello, R. W., Hew, M., Siyue, M. K., Lehmann, S., Lehtimäki, L., Peters, M., Taillé, C., Taube, C., Tran, T. N., Zangrilli, J., Bulathsinhala, L., Carter, V. A., Chaudhry, I., Eleangovan, N., Hosseini, N., Kerkhof, M., Murray, R. B., Price, C. A. & Price, D. B., Sept 2021, In: Chest. 160, 3, p. 814-830

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158 Citations (Scopus)

174 Downloads (Pure)

Factors Associated with Frequent Exacerbations in the UK Severe Asthma Registry

Yang, F., Busby, J., Heaney, L., Menzies-Gow, A., Pfeffer, P. E., Jackson, D. J., Mansur, A. H., Siddiqui, S., Brightling, C. E., Niven, R., Thomson, N. C. & Chaudhuri, R., 15 Jan 2021, (Early online date) In: The Journal of Allergy and Clinical Immunology: In Practice.

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18 Citations (Scopus)

73 Downloads (Pure)

Impact of Socioeconomic Status on Adult Patients with Asthma: A Population-Based Cohort Study from UK Primary Care

Busby, J., Price, D., Al-Lehebi, R., Bosnic-Anticevich, S., van Boven, J., Emmanuel, B., FitzGerald, J., Gaga, M., Hansen, S., Hew, M., Iwanaga, T., Larenas Linnemann, D., Mahboub, B., Mitchell, P., Morrone, D., Pham, J., Porsbjerg, C., Roche, N., Wang, E. & Eleangovan, N. & 1 others, Heaney, L., 10 Nov 2021, In: Journal of Asthma and Allergy. 14, p. 1375-1388 14 p.

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21 Citations (Scopus)

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Potential Severe Asthma Hidden in UK Primary Care

Ryan, D., Heatley, H., Heaney, L. G., Jackson, D. J., Pfeffer, P. E., Busby, J., Menzies-Gow, A. N., Jones, R., Tran, T. N., Al-Ahmad, M., Backer, V., Belhassen, M., Bosnic-Anticevich, S., Bourdin, A., Bulathsinhala, L., Carter, V., Chaudhry, I., Eleangovan, N., FitzGerald, J. M. & Gibson, P. G. & 6 others, Hosseini, N., Kaplan, A., Murray, R. B., Rhee, C. K., Van Ganse, E. & Price, D. B., Apr 2021, In: The Journal of Allergy and Clinical Immunology: In Practice. 9, 4, p. 1612-1623.e9

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49 Citations (Scopus)

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Socioeconomic disparities in asthma healthcare utilization, exacerbations and mortality: A systematic review and meta-analysis

Redmond, C., Akinoso-Imran, A. Q., Heaney, L., Sheikh, A., Kee, F. & Busby, J., 18 Oct 2021, (Early online date) In: Journal of Allergy and Clinical Immunology.

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29 Citations (Scopus)

213 Downloads (Pure)

The inflammatory profile of exacerbations in patients with severe refractory eosinophilic asthma receiving mepolizumab (the MEX study): a prospective observational study

McDowell, P. J., Diver, S., Yang, F., Borg, C., Busby, J., Brown, V., Shrimanker, R., Cox, C., Brightling, C. E., Chaudhuri, R., Pavord, I. D. & Heaney, L. G., 01 Oct 2021, In: The Lancet Respiratory Medicine. 9, 10, p. 1174-1184

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69 Citations (Scopus)

826 Downloads (Pure)

John Busby

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