Research output per year
Research output per year
- 43 results
Search results
-
2022
Fast Ion-Beam Inactivation of Viruses, Where Radiation Track Structure Meets RNA Structural Biology
Villagomez-Bernabe, B., Chan, S. W., Coulter, J. A., Roseman, A. M. & Currell, F. J., 18 Apr 2022, (Early online date) In: Radiation Research. 198Research output: Contribution to journal › Article › peer-review
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2021
Exploiting the anticancer effects of a nitrogen bisphosphonate nanomedicine for glioblastoma multiforme
Jena, L. N., Bennie, L. A., McErlean, E. M., Pentlavalli, S., Glass, K., Burrows, J. F., Kett, V. L., Buckley, N. E., Coulter, J. A., Dunne, N. J. & McCarthy, H. O., 04 May 2021, In: Journal of nanobiotechnology. 19, 1, p. 127Research output: Contribution to journal › Article › peer-review
Open AccessFile59 Downloads (Pure) -
Formulating RALA/Au nanocomplexes to enhance nanoparticle internalisation efficiency, sensitising prostate tumour models to radiation treatment
Bennie, L. A., Feng, J., Emerson, C., Hyland, W. B., Matchett, K. B., McCarthy, H. O. & Coulter, J. A., 19 Sep 2021, In: Journal of nanobiotechnology. 19, 279 .Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Downloads (Pure) -
Hypoxia-targeted cupric-tirapazamine liposomes potentiate radiotherapy in prostate cancer spheroids
Silva, V. L., Ruiz, A., Ali, A., Pereira, S., Seitsonen, J., Ruokolainen, J., Furlong, F., Coulter, J. & Al-Jamal, W. T., 25 Sep 2021, In: International journal of pharmaceutics. 607, 121018.Research output: Contribution to journal › Article › peer-review
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Novel tip-loaded dissolving and implantable microneedle array patches for sustained release of finasteride
Paredes, A. J., Volpe-Zanutto, F., Permana, A. D., Murphy, A. J., Picco, C. J., Vora, L. K., Coulter, J. A. & Donnelly, R. F., 05 Sep 2021, In: International journal of pharmaceutics. 606, 120885.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
2020
Clinical and functional characterization of CXCR1/CXCR2 biology in the relapse and radiotherapy resistance of primary PTEN-deficient prostate carcinoma
Armstrong, C., Ong, C. W., Maxwell, P., O'Sullivan, J., Prise, K., Butterworth, K., Coulter, J., Walker, S., Oksana, L., Gallagher, R., Jain, S., Bristow, R. G., Mills, I., Waugh, D. & LaBonte Wilson, M., Sep 2020, In: NAR Cancer. 2, 3, zcaa012.Research output: Contribution to journal › Article › peer-review
Open AccessFile40 Downloads (Pure) -
Polymer-Supported Gold Nanoparticle Radiosensitizers with Enhanced Cellular Uptake Efficiency and Increased Cell Death in Human Prostate Cancer Cells
Bennie, L., Belhout, S. A., Quinn, S. J. & Coulter, J. A., 19 Mar 2020, In: ACS Applied Nano Materials.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)114 Downloads (Pure) -
2019
Cell-Penetrating Peptides as a Tool for the Cellular Uptake of a Genetically Modified Nitroreductase for use in Directed Enzyme Prodrug Therapy
Anderson, S. D., Hobbs, R. J., Gwenin, V. V., Ball, P., Bennie, L. A., Coulter, J. A. & Gwenin, C. D., 01 Oct 2019, In: Journal of Functional Biomaterials. 10, 4Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
DNA vaccination via RALA nanoparticles in a microneedle delivery system induces a potent immune response against the endogenous prostate cancer stem cell antigen
Cole, G., Ali, A. A., McErlean, E., Mulholland, E. J., Short, A., McCrudden, C. M., McCaffrey, J., Robson, T., Kett, V. L., Coulter, J. A., Dunne, N. J., Donnelly, R. F. & McCarthy, H. O., 09 Jul 2019, (Early online date) In: Acta Biomaterialia. 96, p. 480Research output: Contribution to journal › Article › peer-review
Open AccessFile22 Citations (Scopus)341 Downloads (Pure) -
Nuclear Uptake of Gold Nanoparticles Deduced Using Dual-Angle X-Ray Fluorescence Mapping
McCulloch, A., Bennie, L., Coulter, J. A., McCarthy, H. O., Dromey, B., Grimes, D. R., Quinn, P., Villagomez-Bernabe, B. & Currell, F., 01 Jan 2019, In: Particle and Particle Systems Characterization. 1900140.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
2018
Gene Therapy With RALA/iNOS Composite Nanoparticles Significantly Enhances Survival In A Model Of Metastatic Prostate Cancer
McCrudden, C., McBride, J., McCaffrey, J., McErlean, E., Dunne, N., Kett, V., Coulter, J., Robson, T. & McCarthy, H., 01 Jun 2018, In: Cancer Nanotechnology.Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Citations (Scopus)206 Downloads (Pure) -
Octaarginine-modified gold nanoparticles enhance the radiosensitivity of human colorectal cancer cell line LS180 to megavoltage radiation
Zhang, X., Wang, H., Coulter, J. A. & Yang, R., 19 Jun 2018, In: International Journal of Nanomedicine. 13, p. 3541-3552Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)176 Downloads (Pure) -
Towards photon radiotherapy treatment planning with high Z nanoparticle radiosensitisation agents: the Relative Biological Effective Dose (RBED) framework
Brown, J., Hanna, G., Lampe, N., Villagomez-Bernabe, B. A., Nicol, J., Coulter, J. & Currell, F., 09 Nov 2018, In: Cancer Nanotechnology. 9, 9Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)173 Downloads (Pure) -
Unravelling the cell-type dependent radiosensitising effects of gold through the development of a multifunctional gold nanoparticle
Nicol, J. R., Harrison, E., O'Neill, S. M., Dixon, D., McCarthy, H. O. & Coulter, J. A., 01 Feb 2018, In: Nanomedicine: Nanotechnology, Biology and Medicine. 14, 2, p. 439-449Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)248 Downloads (Pure) -
2017
A hierarchical Bayesian approach to calibrating the linear-quadratic model from clonogenic survival assay data
Collis, J., Hill, M. R., Nicol, J. R., Paine, P. J. & Coulter, J. A., Sep 2017, In: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 124, 3, p. 541-546Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)200 Downloads (Pure) -
Erythropoietin drives breast cancer progression by activation of its receptor EPOR
Chan, K. K., Matchett, K. B., Coulter, J. A., Hiu-Fung, Y., McCrudden, C. M., Zhang, S-D., Irwin, G. W., Davidson, M. A., Rülicke, T., Schober, S., Hengst, L., Jaekel, H., Platt-Higgins, A., Rudland, P. S., Mills, K. I., Maxwell, P., El-Tanani, M. & Lappin, T. R., 18 Mar 2017, In: Oncotarget. 8, 24, p. 38251-38263 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (Scopus)289 Downloads (Pure) -
Systemic RALA/iNOS nanoparticles; a potent gene therapy for metastatic breast cancer coupled as a biomarker of treatment
McCrudden, C. M., McBride, J. W., McCaffrey, J., Ali, A. A., Dunne, N. J., Kett, V. L., Coulter, J. A., Robson, T. & McCarthy, H. O., 17 Mar 2017, In: Molecular Therapy: Nucleic Acids. 6, p. 249-258 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Citations (Scopus)262 Downloads (Pure) -
2016
A comparison of gold nanoparticle surface co-functionalization approaches using Polyethylene Glycol (PEG) and the effect on stability, non-specific protein adsorption and internalization
Harrison, E., Nicol, J. R., Macias-Montero, M., Burke, G. A., Coulter, J. A., Meenan, B. J. & Dixon, D., 01 May 2016, In: Materials Science and Engineering C: Materials for Biological Applications. 62, p. 710-8 9 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
Development of TMTP-1 targeted designer biopolymers for gene delivery to prostate cancer
McBride, J. W., Massey, A. S., McCaffrey, J., McCrudden, C. M., Coulter, J. A., Dunne, N. J., Robson, T. & McCarthy, H. O., 16 Mar 2016, In: International Journal of Pharmaceutics. 500, 1-2, p. 144-153 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)335 Downloads (Pure) -
Gold nanoparticle surface functionalization: mixed monolayer versus hetero bifunctional peg linker
Harrison, E., Coulter, J. A. & Dixon, D., Apr 2016, In: Nanomedicine. 11, 7, p. 851-865 15 p.Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus) -
Imaging and radiation effects of gold nanoparticles in tumour cells
McQuaid, H. N., Muir, M. F., Taggart, L. E., McMahon, S. J., Coulter, J. A., Hyland, W. B., Jain, S., Butterworth, K. T., Schettino, G., Prise, K. M., Hirst, D., Botchway, S. W. & Currell, F., 20 Jan 2016, In: Scientific Reports. 6, 10 p., 19442.Research output: Contribution to journal › Article › peer-review
Open AccessFile82 Citations (Scopus)274 Downloads (Pure) -
Multifunctional and robust composite materials comprising gold nanoparticles at a spherical polystyrene particle surface
Belhout, S. A., Kim, J. Y., Hinds, D. T., Owen, N. J., Coulter, J. A. & Quinn, S. J., 28 Dec 2016, In: Chemical Communications. 52, 100, p. 14388-14391 4 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)265 Downloads (Pure) -
Preclincial evaluation of Gold-DTDTPA Nanoparticles As Theranostic Agents In Prostate Cancer Radiotherapy
Butterworth, K. T., Nicol, J. R., Ghita, M., Rosa, S., Chaudhary, P., McGarry, C. K., McCarthy, H. O., Jimenez-Sanchez, G., Bazzi, R., Roux, S., Tillement, O., Coulter, J. A. & Prise, K. M., Aug 2016, In: Nanomedicine. 11, 16, p. 2035-47 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile31 Citations (Scopus)423 Downloads (Pure) -
Transcending epithelial and intracellular biological barriers; a prototype DNA delivery device
McCaffrey, J., McCrudden, C. M., Ali, A. A., Massey, A. S., McBride, J. W., McCrudden, M. T. C., Vicente-Perez, E. M., Coulter, J. A., Robson, T., Donnelly, R. F. & McCarthy, H. O., 28 Mar 2016, In: Journal of controlled release : official journal of the Controlled Release Society. 226, p. 238-47 10 p.Research output: Contribution to journal › Article › peer-review
35 Citations (Scopus) -
2015
CD44 increases the efficiency of distant metastasis of breast cancer
McFarlane, S., Coulter, J. A., Tibbits, P., O'Grady, A., McFarlane, C., Montgomery, N., Hill, A., McCarthy, H. O., Young, L. S., Kay, E. W., Isacke, C. M. & Waugh, D. J. J., May 2015, In: Oncotarget. 6, 13, p. 11465-11476Research output: Contribution to journal › Article › peer-review
Open AccessFile57 Citations (Scopus)279 Downloads (Pure) -
Gold nanoparticle surface functionalization: a necessary requirement in the development of novel nanotherapeutics
Nicol, J. R., Dixon, D. & Coulter, J. A., 2015, In: Nanomedicine. 10, 8, p. 1315-1326 12 p.Research output: Contribution to journal › Article › peer-review
File54 Citations (Scopus)2415 Downloads (Pure) -
Imaging intracellular and systemic in vivo gold nanoparticles to enhance radiotherapy
Botchway, S. W., Coulter, J. A. & Currell, F. J., 01 Oct 2015, In: British Journal of Radiology. 88, 1054, 13 p., 20150170.Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Citations (Scopus)136 Downloads (Pure) -
2014
Gold nanoparticle cellular uptake, toxicity and radiosensitisation in hypoxic conditions
Jain, S., Coulter, J. A., Butterworth, K. T., Hounsell, A. R., McMahon, S. J., Hyland, W. B., Muir, M. F., Dickson, G. R., Prise, K. M., Currell, F. J., Hirst, D. G. & O'Sullivan, J. M., Feb 2014, In: Radiotherapy and Oncology. 110, 2, p. 342-347 6 p.Research output: Contribution to journal › Article › peer-review
56 Citations (Scopus) -
2013
Potentiation of Inflammatory CXCL8 Signalling Sustains Cell Survival in PTEN-deficient Prostate Carcinoma
Maxwell, P. J., Coulter, J., Walker, S. M., McKechnie, M., Neisen, J., McCabe, N., Kennedy, R. D., Salto-Tellez, M., Albanese, C. & Waugh, D. J. J., Aug 2013, In: European Urology. 64, 2, p. 177-188 12 p.Research output: Contribution to journal › Article › peer-review
49 Citations (Scopus) -
Radiosensitising Nanoparticles as Novel Cancer Therapeutics — Pipe Dream or Realistic Prospect?
Coulter, J. A., Hyland, W. B., Nicol, J. & Currell, F. J., Oct 2013, In: Clinical Oncology. 25, 10, p. 593-603 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile53 Citations (Scopus)463 Downloads (Pure) -
The contribution of N₂O₃ to the cytotoxicity of the nitric oxide donor DETA/NO: an emerging role for S-nitrosylation
Ali, A. A., Coulter, J. A., Ogle, C. H., Migaud, M. M., Hirst, D. G., Robson, T. & McCarthy, H. O., 01 Apr 2013, In: Bioscience Reports. 33, 2, p. 333-349 23 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus)225 Downloads (Pure) -
2012
Cell type-dependent uptake, localization, and cytotoxicity of 1.9 nm gold nanoparticles
Coulter, J. A., Jain, S., Butterworth, K. T., Taggart, L. E., Dickson, G. R., McMahon, S. J., Hyland, W. B., Muir, M. F., Trainor, C., Hounsell, A. R., O'Sullivan, J. M., Schettino, G., Currell, F. J., Hirst, D. G. & Prise, K. M., 2012, In: International Journal of Nanomedicine. 7, null, p. 2673-2685 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile143 Citations (Scopus)687 Downloads (Pure) -
2011
Biological consequences of nanoscale energy deposition near irradiated heavy atom nanoparticles
McMahon, S., Hyland, W., Muir, M., Coulter, J., Jain, S., Butterworth, K., Schettino, G., Dickson, G., Hounsell, A., O'Sullivan, J., Prise, K., Hirst, D. & Currell, F., 20 Jun 2011, In: Nature Scientific Reports. 1, 18.Research output: Contribution to journal › Article › peer-review
File271 Citations (Scopus)240 Downloads (Pure) -
Energy Dependence of Gold Nanoparticle Radiosensitization in Plasmid DNA
McMahon, S., Hyland, W. B., Brun, E., Butterworth, K., Coulter, J., Douki, T., Hirst, D., Jain, S., Kavanagh, A., Krpetic, Z., Mendenhall, M. H., Muir, M. F., Prise, K., Requardt, H., Sanche, L., Schettino, G., Currell, F. & Sicard-Roselli, C., 20 Oct 2011, In: Journal of Physical Chemistry C. 115, 41, p. 20160-20167 8 p.Research output: Contribution to journal › Article › peer-review
39 Citations (Scopus) -
Nanodosimetric effects of gold nanoparticles in megavoltage radiation therapy
McMahon, S., Hyland, W., Muir, M. F., Coulter, J., Jain, S., Butterworth, K., Schettino, G., Dickson, G., Hounsell, A., O'Sullivan, J., Prise, K., Hirst, D. & Currell, F., Sep 2011, In: Radiotherapy and Oncology. 100, 3, p. 412-416 5 p.Research output: Contribution to journal › Article › peer-review
137 Citations (Scopus) -
2010
Evaluation of cytotoxicity and radiation enhancement using 1.9 nm gold particles: potential application for cancer therapy.
Butterworth, K., Jain, S., Coulter, J., Folker, J., McMahon, S., Schettino, G., Prise, K., Currell, F. & Hirst, D., Jun 2010, In: Nanotechnology. 21(29), 29, p. 295101-295110 10 p., 295101.Research output: Contribution to journal › Article › peer-review
172 Citations (Scopus) -
Transcriptional regulation of inducible nitric oxide synthase gene therapy: targeting early stage and advanced prostate cancer.
Coulter, J., Page, N., Worthington, J., Robson, T., Hirst, D. & McCarthy, H., Sep 2010, In: The Journal of Gene Medicine. 12(9), 9, p. 755-765 11 p.Research output: Contribution to journal › Article › peer-review
21 Citations (Scopus) -
2009
Nitric oxide synthase gene therapy enhances the toxicity of cisplatin in cancer cells.
Adams, C., McCarthy, H., Coulter, J., Worthington, J., Murphy, C., Robson, T. & Hirst, D., Feb 2009, In: The Journal of Gene Medicine. 11(2), 2, p. 160-168 9 p.Research output: Contribution to journal › Article › peer-review
36 Citations (Scopus) -
2008
Development of a novel PSMA-driven gene therapy strategy for the treatment of prostate cancer
Page, N. L., Coulter, J., Robson, T., Mc Carthy, H. O. & Hirst, D., Apr 2008, In: Human Gene Therapy. 19, p. 422-422 1 p.Research output: Contribution to journal › Article › peer-review
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Gene therapy via inducible nitric oxide synthase: a tool for the treatment of a diverse range of pathological conditions.
McCarthy, H., Coulter, J., Robson, T. & Hirst, D., Aug 2008, In: Journal of Pharmacy and Pharmacology. 60(8), 8, p. 999-1017 19 p.Research output: Contribution to journal › Article › peer-review
28 Citations (Scopus) -
Nitric oxide-A novel therapeutic for cancer.
Coulter, J., McCarthy, H., Xiang, J., Roedl, W., Wagner, E., Robson, T. & Hirst, D., Sep 2008, In: Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society. 19(2), 2, p. 192-198 7 p.Research output: Contribution to journal › Article › peer-review
87 Citations (Scopus) -
The radiation-inducible pE9 promoter driving inducible nitric oxide synthase radiosensitizes hypoxic tumour cells to radiation
Coulter, JA., McCarthy, HO., Worthington, J., Robson, T., Scott, S. & Hirst, DG., Apr 2008, In: Gene Therapy. 15, 7, p. 495-503 9 p.Research output: Contribution to journal › Article › peer-review
21 Citations (Scopus) -
2007
Human Osteocalcin: a strong promoter for nitric oxide synthase gene therapy, with specificity for hormone refractory prostate cancer.
McCarthy, H., Coulter, J., Worthington, J., Robson, T. & Hirst, D., May 2007, In: The Journal of Gene Medicine. 9(6), 6, p. 511-520 10 p.Research output: Contribution to journal › Article › peer-review
18 Citations (Scopus)