Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Joseph Samuel Vyle is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Projects
- 1 Finished
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Synthesis and anticancer activity of selenium-substituted dinucleoside tetraphosphate analogues
Vyle, J. S., Wilson, J., Eguaogie, O., Conlon, P., Hale, L. & McCarthy, H., Sept 2024, p. 18. 1 p.Research output: Contribution to conference › Poster › peer-review
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Synthesis and characterisation of a nucleotide based pro-drug formulated with a peptide into a nano-chemotherapy for colorectal cancer
Wilson, J. J., Bennie, L., Eguaogie, O., Elkashif, A., Conlon, P. F., Jena, L., McErlean, E., Buckley, N., Englert, K., Dunne, N. J., Tucker, J. H. R., Vyle, J. S. & McCarthy, H. O., May 2024, In: Journal of Controlled Release. 369, p. 63-74 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)32 Downloads (Pure) -
5'-Chalcogen-substituted Nucleoside Pyrophosphate and Phosphate Monoester analogues: preparation and hydrolysis studies
Mikkola, S., Eguaogie, O., Nieminen, A., Conlon, P. F., Jakeman, D. L., Moore, K., Lane, I. C. & Vyle, J. S., 08 Dec 2022, In: International Journal of Molecular Sciences. 23, 24, 16 p., 15582.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)136 Downloads (Pure) -
Solid-phase synthesis and structural characterisation of phosphoroselenolate-modified DNA: a backbone analogue which does not impose conformational bias and facilitates SAD X-ray crystallography
Conlon, P., Eguaogie, O., Wilson, J., Sweet, J., Steinhoegl, J., Englert , K., Hancox, O., Law, C., Allman, S., Tucker, J. H. R., Hall, J. & Vyle, J., 11 Oct 2019, In: Chemical Science. 10, p. 10948-10957 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)206 Downloads (Pure) -
Mechanochemistry of nucleosides, nucleotides and related materials
Eguaogie, O., Vyle, J. S., Conlon, P. F., Gîlea, M. A. & Liang, Y., 27 Apr 2018, In: Beilstein Journal of Organic Chemistry . 14, p. 955-970 16 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile63 Citations (Scopus)292 Downloads (Pure)
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The Preparation and evaluation of Photoswitchable nucleic acids
Vyle, J. S. (Speaker)
03 Oct 2012Activity: Talk or presentation types › Invited talk
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8th Nucleic Acids Forum
Vyle, J. S. (Session chair)
06 Jul 2012Activity: Participating in or organising an event types › Participation in conference
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Nucleic Acids Chemistry & Biology 6th Cambridge Symposium
Vyle, J. S. (Participant)
04 Sept 2011 → 07 Sept 2011Activity: Participating in or organising an event types › Participation in conference
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Nucleic Acids Chemistry & Biology 6th Cambridge Symposium
Vyle, J. S. (Participant)
04 Sept 2011 → 07 Sept 2011Activity: Participating in or organising an event types › Participation in conference
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7th Nucleic Acids Forum
Vyle, J. S. (Speaker)
08 Jul 2011Activity: Participating in or organising an event types › Participation in conference