Julia Miskelly

Dr

  • Room 0B.004 - CCRCB Block 5 MBC Site

    United Kingdom

20032016
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Fingerprint Dive into the research topics where Julia Miskelly is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 19 Similar Profiles
DNA Damage Medicine & Life Sciences
Estrogen Receptor alpha Medicine & Life Sciences
Genomic Instability Medicine & Life Sciences
Breast Neoplasms Medicine & Life Sciences
Etoposide Medicine & Life Sciences
DNA Repair Medicine & Life Sciences
Cell Cycle Checkpoints Medicine & Life Sciences
Genes Medicine & Life Sciences

Research Output 2003 2016

4 Citations (Scopus)

The identification of a novel role for BRCA1 in regulating RNA Polymerase I transcription

Johnston, R., D'Costa, Z., Ray, S., Gorski, J., Harkin, D. P., Mullan, P. & Panov, K. I., 31 Aug 2016, In : Oncotarget. 14 p.

Research output: Contribution to journalArticle

Open Access
File
DNA Damage
Ribosomal DNA
Ribosomes
Holoenzymes
Nucleic Acid Regulatory Sequences
54 Citations (Scopus)

BRCA1 Deficiency Exacerbates Estrogen-Induced DNA Damage and Genomic Instability

Savage, K. I., Matchett, K. B., Barros, E. M., Cooper, K. M., Irwin, G. W., Gorski, J. J., Orr, K. S., Vohhodina, J., Kavanagh, J. N., Madden, A. F., Powell, A., Manti, L., McDade, S. S., Park, B. H., Prise, K. M., McIntosh, S. A., Salto-Tellez, M., Richard, D. J., Elliott, C. T., Harkin, D. P. & 1 othersMcDade, S., 15 May 2014, In : Cancer Research. 74, 10, p. 2773-2784 12 p.

Research output: Contribution to journalArticle

Genomic Instability
DNA Damage
Estrogens
DNA Repair
Mutation
78 Citations (Scopus)

Identification of a BRCA1-mRNA Splicing Complex Required for Efficient DNA Repair and Maintenance of Genomic Stability

Savage, K. I., Gorski, J. J., Barros, E. M., Irwin, G. W., Manti, L., Powell, A. J., Pellagatti, A., Lukashchuk, N., McCance, D. J., McCluggage, W. G., Schettino, G., Salto-Tellez, M., Boultwood, J., Richard, D. J., McDade, S. S. & Harkin, D. P., 08 May 2014, In : Molecular Cell. 54, 3, p. 445-459 15 p.

Research output: Contribution to journalArticle

Open Access
File
Genomic Instability
DNA Repair
DNA Damage
Maintenance
Messenger RNA
22 Citations (Scopus)

NF-κB is a critical mediator of BRCA1-induced chemoresistance

Harte, M. T., Gorski, J. J., Savage, K. I., Purcell, J. W., Barros, E. M., Burn, P. M., McFarlane, C., Mullan, P. B., Kennedy, R. D., Perkins, N. D. & Harkin, D. P., 06 Feb 2014, In : Oncogene. 33, 6, p. 713-723 11 p.

Research output: Contribution to journalArticle

DNA Damage
Camptothecin
Etoposide
DNA
Neoplasms
43 Citations (Scopus)

BRCA1 and GATA3 corepress FOXC1 to inhibit the pathogenesis of basal-like breast cancers

Tkocz, D., Crawford, N., Buckley, N. E., Berry, F. B., Kennedy, R., Miskelly, J., Harkin, P. & Mullan, P., 09 Dec 2011, In : Oncogene. 531, 32, p. 3667-3678 12 p.

Research output: Contribution to journalArticle

Breast Neoplasms
GATA3 Transcription Factor
BRCA1 Protein
Epithelial-Mesenchymal Transition
Mutant Proteins

Impact

Development and Commercialization of a Technology Platform to Enable Biomarker Discovery and Validation

Richard Kennedy (Participant), Paul Harkin (Participant), Patrick Johnston (Participant), Alison Hosey (Participant), Julia Miskelly (Participant), Margaret Murray (Participant), Jennifer Quinn (Participant), Colin James (Participant), Jude Mulligan (Participant), Peter Daly (Participant), Paul Mullan (Participant), Julie Mussen (Participant), Ultan McDermott (Participant), Richard Wilson (Participant), Daniel Longley (Participant)

Impact: Health Impact, Quality of Life Impact

Facilities

Genomics Core Technology Unit

Julia Miskelly (Manager)

Facility/equipment: Facility

DNA sequences
Profitability
Robotics
Genomics
Experiments