Julia Miskelly

Dr

20032016

Research output per year

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Research Output

2016

The identification of a novel role for BRCA1 in regulating RNA Polymerase I transcription

Johnston, R., D'Costa, Z., Ray, S., Gorski, J., Harkin, D. P., Mullan, P. & Panov, K. I., 31 Aug 2016, In : Oncotarget. 14 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
268 Downloads (Pure)
2014

BRCA1 Deficiency Exacerbates Estrogen-Induced DNA Damage and Genomic Instability

Savage, K. I., Matchett, K. B., Barros, E. M., Cooper, K. M., Irwin, G. W., Gorski, J. J., Orr, K. S., Vohhodina, J., Kavanagh, J. N., Madden, A. F., Powell, A., Manti, L., McDade, S. S., Park, B. H., Prise, K. M., McIntosh, S. A., Salto-Tellez, M., Richard, D. J., Elliott, C. T., Harkin, D. P. & 1 others, McDade, S., 15 May 2014, In : Cancer Research. 74, 10, p. 2773-2784 12 p.

Research output: Contribution to journalArticle

57 Citations (Scopus)

Identification of a BRCA1-mRNA Splicing Complex Required for Efficient DNA Repair and Maintenance of Genomic Stability

Savage, K. I., Gorski, J. J., Barros, E. M., Irwin, G. W., Manti, L., Powell, A. J., Pellagatti, A., Lukashchuk, N., McCance, D. J., McCluggage, W. G., Schettino, G., Salto-Tellez, M., Boultwood, J., Richard, D. J., McDade, S. S. & Harkin, D. P., 08 May 2014, In : Molecular Cell. 54, 3, p. 445-459 15 p.

Research output: Contribution to journalArticle

Open Access
File
83 Citations (Scopus)
235 Downloads (Pure)

NF-κB is a critical mediator of BRCA1-induced chemoresistance

Harte, M. T., Gorski, J. J., Savage, K. I., Purcell, J. W., Barros, E. M., Burn, P. M., McFarlane, C., Mullan, P. B., Kennedy, R. D., Perkins, N. D. & Harkin, D. P., 06 Feb 2014, In : Oncogene. 33, 6, p. 713-723 11 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
2011

BRCA1 and GATA3 corepress FOXC1 to inhibit the pathogenesis of basal-like breast cancers

Tkocz, D., Crawford, N., Buckley, N. E., Berry, F. B., Kennedy, R., Miskelly, J., Harkin, P. & Mullan, P., 09 Dec 2011, In : Oncogene. 531, 32, p. 3667-3678 12 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)
2010

BRD7, a subunit of SWI/SNF complexes, binds directly to BRCA1 and regulates BRCA1-dependent transcription

Harte, M. T., O'Brien, G. J., Ryan, N. M., Gorski, J. J., Savage, K. I., Crawford, N. T., Mullan, P. B. & Harkin, D. P., 15 Mar 2010, In : Cancer Research. 70, 6, p. 2538-2547 10 p.

Research output: Contribution to journalArticle

73 Citations (Scopus)
2008

Response: Re: Molecular Basis for Estrogen Receptor α Deficiency in BRCA1-Linked Breast Cancer

Hosey, A. M., Gorski, J. J., Quinn, J. E., Chung, W. Y., McCann, A. & Harkin, D. P., 2008, In : Journal of the National Cancer Institute. 100, 10, p. 753-754 2 p.

Research output: Contribution to journalArticle

2007

BRCA1 Regulates IFN-γ Signaling through a Mechanism Involving the Type I IFNs

Buckley, N., Hosey, A. M., Gorski, J. J., Purcell, J. W., Mulligan, J. M., Harkin, D. P. & Mullan, P. B., Mar 2007, In : Molecular Cancer Research. 5, 3, p. 261-270 10 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Molecular basis for estrogen receptor alpha deficiency in BRCA1-linked breast cancer

Hosey, A. M., Gorski, J. J., Murray, M. M., Quinn, J. E., Chung, W. Y., Stewart, G. E., James, C. R., Farragher, S. M., Mulligan, J. M., Scott, A. N., Dervan, P. A., Johnston, P. G., Couch, F. J., Daly, P. A., Kay, E., McCann, A., Mullan, P. B. & Harkin, D. P., 21 Nov 2007, In : Journal of the National Cancer Institute. 99, 22, p. 1683-1694 12 p.

Research output: Contribution to journalArticle

157 Citations (Scopus)
2005

BRCA1 and c-Myc Associate to Transcriptionally Repress Psoriasin, a DNA Damage-Inducible Gene

Kennedy, R. D., Gorski, J. J., Quinn, J. E., Stewart, G. E., James, C. R., Moore, S., Mulligan, K., Emberley, E. D., Lioe, T. F., Morrison, P. J., Mullan, P. B., Reid, G., Johnston, P. G., Watson, P. H. & Harkin, D. P., 15 Nov 2005, In : Cancer Research. 65, 22, p. 10265-10272 8 p.

Research output: Contribution to journalArticle

64 Citations (Scopus)
2004

BRCA1 Interacts with and Is Required for Paclitaxel-Induced Activation of Mitogen-Activated Protein Kinase Kinase Kinase 3

Gilmore, P. M., McCabe, N., Liu, E. T., O'Brien, J., Kennedy, R., Mullan, P., Miskelly, J., Andrews, H. N., McWilliams, S., Carty, M., Duprex, P., Johnston, P. & Harkin, P., 15 Jun 2004, In : Cancer Research. 64(12), 12, p. 4148-4154 7 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)
2003

Identification and characterisation of a BRCA1 MAD1 protein complex.

Carty, M., Gilmore, P., Harte, M., Quinn, J., McCabe, N., Harkin, DP., Gorski, JJ. & Harkin, D., 01 Dec 2003, In : Clinical Cancer Research. 9, 16, 2, S, p. 6219S-6220S

Research output: Contribution to journalArticle