Projects per year
Personal profile
Research Statement
Dr. Tian, BEng (Honour), MSc, PhD, is a Senior Lecturer (Associate Professor) in Pharmaceutical Engineering at Queen's University Belfast and a Royal Academy of Engineering Enterprise Fellow (2019/20). He has completed his bachelor's in Macromolecular Materials and Engineering from Beijing Institute of Technology, MSc in Process Engineering, and PhD in Pharmaceutics.
Dr Tian is leading a global partnership and collaboration to tackle essential antifungal nanomedicine shortages through advanced process engineering. He has secured external funding of >£900,000 as Principal Investigator and >£500,000 as Co-Investigator from highly competitive sources, i.e., UKRI, leading charities, and Innovate UK (2023). The Medical Research Council (MRC) has awarded the current collaborative project to develop transformational advanced manufacturing technology for sustainable production and supply of antifungal nanomedicines (EnLAmB project, 2023-2025, PI, MR/X014010/1).
His established research and innovation networks include:
The Centre for Infectious Disease (University of Liverpool); A Global Network for Neglected Tropical Diseases/GCRF (University of Durham); The London School of Hygiene and Tropical Medicine; The Institute of Infection Diseases and Immunity (St George's Hospital); EPSRC Centre for Nature Inspired Engineering (UCL); Botswana-Harvard AIDS Institute Partnership (Botswana); Drug for Neglected Diseases Initiatives (DNDi)
Dr Tian's group is looking for talented student/PDRA in the following areas:
1. High throughput screening and digital design of nanocarriers
2. Microrheology modelling for extracellular matrices
3. Metastable systems in drug delivery
Achievements
Royal Academy of Engineering Enterprise Fellow
Teaching
I have been coordiating and contributed to teaching in both MPharm, BSc and China Queen's Colleges covering areas including:
Pharmaceutical materials and science, pharmaceutical technology, advanced drug delivery, regulatory, process analysis technology and predictive modelling and automation in pharmaceutics.
Interests
As an awardee of the RAEng Enterprise Fellowship and member of RAEng Innovation Hub London, Dr Tian is frequently involved in networking and showcase events, participating in conversations to shape the RAEng investment policies. He is also invited to be in several start-up competitions in a mentoring capacity, such as the RAEng Global Grant Challenge Summit 2019, guiding their start-up ideas.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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R1874PMY: MICA: EnLAmB - Enabling global access to affordable generic liposomal amphotericin B injectable formulations via advanced manufacturing technology
Tian, J. (PI), Al-Jamal, W. (CoI), Andrews, G. (CoI) & Jones, D. (CoI)
10/03/2023 → …
Project: Research
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S2412PMY: KTP/Devenish Nutrition Ltd
Andrews, G. (CoI), Jones, D. (CoI), Li, S. (CoI) & Tian, J. (CoI)
01/05/2017 → …
Project: ktp
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R2855PMY: Enable the scalable manufacturing of generic LAmB with comparable in vivo efficacy against visceral leishmaniasis
Tian, J. (PI)
28/02/2022 → 31/01/2023
Project: Research
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R2582PMY: COMMAND Technology: one step nanomedicine manufacturing
Tian, J. (PI)
01/03/2019 → 29/02/2020
Project: Research
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Kinetic and thermodynamic interplay of polymer-mediated liquid-liquid phase separation for poorly water-soluble drugs
Qian, K., Stella, L., Liu, F., Jones, D. S., Andrews, G. P. & Tian, Y., 03 Jun 2024, In: Molecular Pharmaceutics. 21, 6, p. 2878–2893 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile37 Downloads (Pure) -
Unravelling the interactions between small molecules and liposomal bilayers via molecular dynamics and thermodynamic modelling
Miles, C. M., Cullen, S., Kenaan, H., Gu, W., Andrews, G. P., Sosso, G. C. & Tian, Y., 20 Jul 2024, In: International Journal of Pharmaceutics. 660, 15 p., 124367.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)28 Downloads (Pure) -
High drug loading nanosized amorphous solid dispersion (NASD) with enhanced in vitro solubility and permeability: benchmarking conventional ASD
Andrews, G. P., Qian, K., Jacobs, E., Jones, D. S. & Tian, Y., 05 Feb 2023, In: International Journal of Pharmaceutics. 632, 15 p., 122551.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)195 Downloads (Pure) -
Osteogenic growth peptide (OGP 10-14) peptide-loaded mesoporous silica nanoparticles in the management of rheumatoid arthritis
Shinde, S., Pentlavalli, S., Mishra, D., Baviskar, S. M., Dyawanapelly, S., Tian, J., Vora, L. & Singh, T. R. R., 08 Jun 2023.Research output: Contribution to conference › Poster › peer-review
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Recent clinical successes in liposomal nanomedicines
Gu, W., Andrews, G. P. & Tian, Y., 03 Feb 2023, In: International Journal of Drug Discovery and Pharmacology. 2, 1, p. 52-59Research output: Contribution to journal › Article › peer-review
Open AccessFile110 Downloads (Pure)
Prizes
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Royal Academy of Engineering Enterprise Fellowship
Tian, J. (Recipient), 01 Mar 2019
Prize: Fellowship awarded competitively
Activities
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EnLAmB – An advanced manufacturing technology to produce generic liposomal amphotericin b formulations
Kenaan, H. (Presenter), Duncan, R. (Advisor), Jones, D. (Advisor), Al-Jamal, W. (Advisor), Andrews, G. (Advisor) & Tian, J. (Invited speaker)
12 Nov 2024 → 13 Dec 2024Activity: Talk or presentation types › Invited talk
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Development of Biohydrogel Mimicking Screening Platform for Nanocarrier Selection
Liu, F. (Speaker) & Tian, J. (Speaker)
26 Jan 2024Activity: Talk or presentation types › Oral presentation
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Engineering Approach to Address Global Fungal Challenges
Tian, J. (Invited speaker)
01 Dec 2023Activity: Talk or presentation types › Invited talk
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China Medical University – Queen’s University Belfast Joint College
Tian, J. (Examiner)
20 Sept 2023 → 30 Dec 2023Activity: Visiting an external institution types › Visiting an external academic institution
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China Medical University – Queen’s University Belfast Joint College
Tian, J. (Visiting lecturer)
10 Sept 2023 → 17 Sept 2023Activity: Visiting an external institution types › Research and Teaching at External Organisation