• Room 01.005 - CCRCB

    United Kingdom

19962020

Research output per year

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Research Output

2020

ICI-RS 2019 nocturia think tank: How can experimental science guide us in understanding the pathophysiology of nocturia?

Vahabi, B., Jabr, R., Fry, C., McCloskey, K., Everaert, K., Agudelo, C. W., Monaghan, T. F., Rahnama'i, M. S., Panicker, J. N. & Weiss, J. P., 10 Jan 2020, In : Neurourology and Urodynamics.

Research output: Contribution to journalReview article

2019

New targets for overactive bladder-ICI-RS 2109

Fry, C. H., Chakrabarty, B., Hashitani, H., Andersson, K-E., McCloskey, K., Jabr, R. I. & Drake, M. J., 18 Nov 2019, In : Neurourology and Urodynamics.

Research output: Contribution to journalReview article

Spontaneous Activity and the Urinary Bladder

Fry, C. H. & McCloskey, K. D., 11 Jun 2019, Smooth Muscle Spontaneous Activity. Springer Nature Singapore Pte Ltd., Vol. 1124. p. 121-147 27 p. (Advances in Experimental Medicine and Biology).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

1 Citation (Scopus)
2018

Acute radiation impacts contractility of guinea-pig bladder strips affecting mucosal-detrusor interactions

McDonnell, B. M., Buchanan, P. J., Prise, K. M. & McCloskey, K. D., 07 Mar 2018, In : PloS one. 13, 3, 15 p., e0193923.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
158 Downloads (Pure)

The detrusor-free bladder - it can still hold its water

McCloskey, K. D., 22 Dec 2018, In : The Journal of Physiology.

Research output: Contribution to journalArticle

Open Access
File
37 Downloads (Pure)

What are the origins and relevance of spontaneous bladder contractions? ICI-RS 2017

Drake, M. J., Fry, C. H., Hashitani, H., Kirschner-Hermanns, R., Rahnama'i, M. S., Speich, J. E., Tomoe, H., Kanai, A. J. & McCloskey, K. D., 23 Jan 2018, In : Neurourology and Urodynamics.

Research output: Contribution to journalReview article

4 Citations (Scopus)
2017

Activation of STING-Dependent Innate Immune Signaling By S-Phase-Specific DNA Damage in Breast Cancer

Parkes, E. E., Walker, S. M., Taggart, L. E., McCabe, N., Knight, L. A., Wilkinson, R., McCloskey, K., Buckley, N. E., Savage, K. I., Salto-Tellez, M., McQuaid, S., Harte, M. T., Mullan, P. B., Harkin, D. P. & Kennedy, R. D., 01 Jan 2017, In : Journal of the National Cancer Institute. 109, 1

Research output: Contribution to journalArticle

Open Access
File
89 Citations (Scopus)
598 Downloads (Pure)

Calcium Channel Blocker Use and Risk of Prostate Cancer by TMPRSS2:ERG Gene Fusion Status

Geybels, M. S., McCloskey, K., Mills, I. G. & Stanford, J. L., 15 Feb 2017, In : Prostate. 77, 3, p. 282-290 9 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
158 Downloads (Pure)

Cell Biology

McCloskey, K., Chris, F., Chess-Williams, R., Hashitani, H., Kanai, A., Vahabi, B. & Takeda, M., 31 May 2017, Incontinence: 6th Edition 2017. Wagg, A., Wein, A., Cordozo, L. & Abrams, P. (eds.). 6 ed. International Continence Society, Vol. 1. p. 143 258 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Open Access
File
147 Downloads (Pure)
Open Access
File
1 Citation (Scopus)
178 Downloads (Pure)

Is electrolyte transfer across the urothelium important?: ICI-RS 2015

McCloskey, K. D., Vahabi, B. & Fry, C. H., Apr 2017, In : Neurourology and Urodynamics. 36, 4, p. 863-868 6 p.

Research output: Contribution to journalReview article

4 Citations (Scopus)

Mucosal modulation of contractility in bladder strips from normal and overactive rat models and the effect of botulinum toxin A on overactive bladder strips

Campbell, P. C., McDonnell, B., Monaghan, K. P., Baysting, L., Little, O. & McCloskey, K. D., 25 Apr 2017, In : Neurourology and Urodynamics. 36, 4, p. 1052-1060 9 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
229 Downloads (Pure)

The Athena SWAN journey and its impact on gender equality in the School of Medicine, Dentistry and Biomedical Sciences at Queen's University, Belfast

McCloskey, K. D., 01 Jan 2017, Leadership for Improvement: Perceptions, Influences and Gender Differences. Nova Science Publishers, Inc, p. 157-175 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2016
Open Access
File
24 Citations (Scopus)
220 Downloads (Pure)

The potassium channel KCNK1 as a novel biomarker for the prediction of response in ovarian cancer

Craig, E., McCloskey, K., Beirne, J., McQuaid, S. & Buckley, N. E., 2016.

Research output: Contribution to conferencePoster

Vitamin D3 suppresses morphological evolution of the cribriform cancerous phenotype

Deevi, R., McClements, J., McCloskey, K. D., Fatehullah, A., Tkocz, D., Javadi, A., Higginson, R., Durban, V. M., Jansen, M., Clarke, A., Loughrey, M. & Campbell, F., 02 Aug 2016, In : Oncotarget. 7, 31, p. 49042-49064

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
337 Downloads (Pure)
2015

Emerging role of potassium channels in ovarian cancer

Craig, E., Beirne, J., McCloskey, K. & Buckley, N. E., 2015.

Research output: Contribution to conferencePoster

The Role of Brain-Derived Neurotrophic Factor (BDNF) in the Development of Neurogenic Detrusor Overactivity (NDO)

Frias, B., Santos, J., Morgado, M., Sousa, M. M., Gray, S. M. Y., McCloskey, K., Allen, S., Cruz, F. & Cruz, C. D., 04 Feb 2015, In : The Journal of neuroscience : the official journal of the Society for Neuroscience. 35, 5, p. 2146-60 15 p.

Research output: Contribution to journalArticle

Open Access
File
25 Citations (Scopus)
324 Downloads (Pure)
2014

Lamina propria: The functional center of the bladder?

Andersson, K-E. & McCloskey, K. D., Jan 2014, In : Neurourology and Urodynamics. 33, 1, p. 9-16 8 p.

Research output: Contribution to journalArticle

65 Citations (Scopus)
Open Access
File
24 Citations (Scopus)
219 Downloads (Pure)

TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities.

D'Costa, Z. C., Higgins, C., Ong, C. W., Irwin, G. W., Boyle, D., McArt, D. G., McCloskey, K., Buckley, N. E., Crawford, N. T., Thiagarajan, L., Murray, J. T., Kennedy, R. D., Mulligan, K. A., Harkin, D. P., Waugh, D. J. J., Scott, C. J., Salto-Tellez, M., Williams, R. & Mullan, P. B., 08 Feb 2014, In : Oncotarget. 5, 6, p. 1609-1620 12 p.

Research output: Contribution to journalArticle

Open Access
File
25 Citations (Scopus)
223 Downloads (Pure)
2013

Bladder interstitial cells: an updated review of current knowledge

McCloskey, K., Jan 2013, In : Acta physiologica (Oxford, England). 207, 1, p. 7-15 9 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Functional expression of KCNQ (Kv7) channels in guinea-pig bladder smooth muscle and their contribution to spontaneous activity

Anderson, U. A., Carson, C., Johnston, L., Joshi, S., Gurney, A. M. & McCloskey, K. D., Jul 2013, In : British Journal of Pharmacology. 169, 6, p. 1290-1304 15 p.

Research output: Contribution to journalArticle

Open Access
File
31 Citations (Scopus)
189 Downloads (Pure)
Open Access
File
20 Citations (Scopus)
188 Downloads (Pure)
2012

Altered distribution of interstitial cells and innervation in the rat urinary bladder following spinal cord injury

Johnston, L., Cunningham, R. M. J., Fry, C. H., Young, J. S., McMurray, G., Eccles, R. & McCloskey, K., Jul 2012, In : Journal of Cellular and Molecular Medicine. 16, 7, p. 1533-1543 11 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Identification of PDGFRα Positive Populations of Interstitial Cells in Human and Guinea Pig Bladders.

Monaghan, K., Johnston, L. & McCloskey, K., Aug 2012, In : Journal of Urology. 188(2), 2, p. 639-647 9 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

The passive and active contractile properties of the neurogenic, underactive bladder.

Young, J. S., Johnston, L., Soubrane, C., McCloskey, K., McMurray, G., Eccles, R. & Fry, C. H., 2012, In : BJU International. tbc

Research output: Contribution to journalArticle

18 Citations (Scopus)
2011

Calbindin 2 (CALB2) Regulates 5-Fluorouracil Sensitivity in Colorectal Cancer by Modulating the Intrinsic Apoptotic Pathway

Stevenson, L., Allen, W. L., Proutski, I., Stewart, G., Johnston, L., McCloskey, K., Wilson, P. M., Longley, D. & Johnston, P., 2011, In : PLoS ONE. 6, 5, e20276.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Interstitial Cells and Bladder Pathophysiology-Passive Bystanders or Active Participants?

McCloskey, K., May 2011, In : Journal of Urology. 185, 5, p. 1562-1563 2 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Interstitial Cells of Cajal in the Urinary Tract

McCloskey, K., 2011, Handbook of Experimental Pharmacology - Urinary Tract. Michel, M. C. & Andersson, K. E. (eds.). Springer, p. 233-254 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

35 Citations (Scopus)

Role of Delta Np63 gamma in Epithelial to Mesenchymal Transition

Lindsay, J., McDade, S., Pickard, A., McCloskey, K. & McCance, D., 04 Feb 2011, In : Journal of Biological Chemistry. 286, 5, p. 3915-3924 10 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

The physiological properties of the decompensated, spinal cord injured bladder

Young, J., Johnston, L., McMurray, G., Eccles, R., McCloskey, K. & Fry, C., Aug 2011, In : Neurourology and Urodynamics. 30, 6, p. 932-934 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Ultrastructural Properties of Interstitial Cells of Cajal in the Guinea Pig Bladder

Cunningham, R., Larkin, P. & McCloskey, K., Mar 2011, In : Journal of Urology. 185, 3, p. 1123-1131 9 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2010

Interstitial Cells in the Urinary Bladder-Localization and Function

McCloskey, K., Jan 2010, In : Neurourology and Urodynamics. 29, 1, p. 82-87 6 p.

Research output: Contribution to journalArticle

107 Citations (Scopus)

Morphological Expression of KIT Positive Interstitial Cells of Cajal in Human Bladder

Johnston, L., Woolsey, S., Cunningham, R., O'Kane, H., Duggan, B., Keane, P. & McCloskey, K., Jul 2010, In : Journal of Urology. 184, 1, p. 370-377 8 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)
2009

Comparison of mechanical and electrical activity and interstitial cells of Cajal in urinary bladders from wild-type and W/W-v mice

McCloskey, K., Anderson, U. A., Davidson, R. A., Bayguinov, Y. R., Sanders, K. M. & Ward, S. M., Jan 2009, In : British Journal of Pharmacology. 156, 2, p. 273-283 11 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

KCNQ Currents and Their Contribution to Resting Membrane Potential and the Excitability of Interstitial Cells of Cajal From the Guinea Pig Bladder

Anderson, U., Carson, C. & McCloskey, K., Jul 2009, In : Journal of Urology. 182, 1, p. 330-336 7 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)
2008

Cholinergic-induced Ca2+ signaling in interstitial cells of Cajal from the guinea pig bladder.

Johnston, L., Carson, C., Lyons, A., Davidson, R. & McCloskey, K., Mar 2008, In : American Journal of Physiology - Renal Physiology. 294(3), 3, p. F645-655 11 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)
2007

Kit-positive interstitial cells in the rabbit urethra: structural relationships with nerves and smooth muscle.

Lyons, A. D., Gardiner, T. & McCloskey, K., Mar 2007, In : BJU International. 99, 3, p. 687-694 8 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)
2006

Calcium currents in interstitial cells from the guinea-pig bladder.

McCloskey, K., Jun 2006, In : BJU International. 97(6), 6, p. 1338-1343 6 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
2005

Characterization of outward currents in interstitial cells from the guinea pig bladder.

McCloskey, K., Jan 2005, In : Journal of Urology. 173(1), 1, p. 296-301 6 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Mechanisms of Disease: specialized interstitial cells of the urinary tract--an assessment of current knowledge.

McCloskey, K. & Brading, A. F., Nov 2005, In : Nature clinical practice. Urology. 2(11), 11, p. 546-554 9 p.

Research output: Contribution to journalArticle

91 Citations (Scopus)

Morphology and localization of interstitial cells in the guinea pig bladder: structural relationships with smooth muscle and neurons.

Davidson, R. A. & McCloskey, K., Apr 2005, In : Journal of Urology. 173(4), 4, p. 1385-1390 6 p.

Research output: Contribution to journalArticle

143 Citations (Scopus)
2003

Multiphoton imaging in the detection of malignancy in the oesophagus.

Kendall, C. A., McCloskey, K., Stone, N., Barr, H. & Greenhalgh, D., 2003, In : Proc Soc Photo Opt Instrum Eng. 5139, p. 51-55 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2002

Kit-like immunopositive cells in sheep mesenteric lymphatic vessels.

McCloskey, K., Hollywood, M. A., Thornbury, K. D., Ward, S. M. & McHale, N. G., 2002, In : Cell and Tissue Research. 310(1), 1, p. 77-84 8 p.

Research output: Contribution to journalArticle

75 Citations (Scopus)