Research output per year
Research output per year
- 1 - 50 out of 54 results
Search results
-
2023
CACNA1D overexpression and voltage‑gated calcium channels in prostate cancer during androgen deprivation
McKerr, N., Mohd-Sarip, A., Dorrian, H., Breen, C., James, J. A., McQuaid, S., Mills, I. G. & McCloskey, K. D., 22 Mar 2023, In: Nature Scientific Reports. 13, 4683.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Downloads (Pure) -
Health diplomacy in action: the cancer legacy of the Good Friday Agreement
Lawler, M., Sullivan, R., Abou-Alfa, G. K., McCloskey, K., Keatley, D., Feighan, J., Dahut, W., Mulroe, E., Ladner, R., Genead, M., Lowery, M., Gulley, J. L., Scott, C. J., Longley, D. B., Culhane, A., Gallagher, W. M., Orr, N., Chanock, S. J. & Gopal, S., Dec 2023, In: Journal of Cancer Policy. 38, 3 p., 100448.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Downloads (Pure) -
Key role for Kv11.1 (ether-a-go-go related gene) channels in rat bladder contractility
Barrese, V., Wehbe, Z., Linden, A., McDowell, S., Forrester, E., Povstyan, O., McCloskey, K. D. & Greenwood, I. A., 07 Feb 2023, In: Physiological reports. 11, 3, e15583.Research output: Contribution to journal › Article › peer-review
Open AccessFile188 Downloads (Pure) -
2020
Are oxidative stress and ischemia significant causes of bladder damage leading to lower urinary tract dysfunction? Report from the ICI-RS 2019
Speich, J. E., Tarcan, T., Hashitani, H., Vahabi, B., McCloskey, K. D., Andersson, K. E., Wein, A. J. & Birder, L. A., 01 Jul 2020, In: Neurourology and Urodynamics. 39, S3, p. S16-S22 7 p.Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus) -
Dysfunctional bladder neurophysiology in urofacial syndrome Hpse2 mutant mice
Manak, I., Gurney, A. M., McCloskey, K. D., Woolf, A. S. & Roberts, N. A., 01 Sep 2020, In: Neurourology and Urodynamics. 39, 7, p. 1930-1938 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)61 Downloads (Pure) -
2018
Acute radiation impacts contractility of guinea-pig bladder strips affecting mucosal-detrusor interactions
McDonnell, B. M., Buchanan, P. J., Prise, K. M. & McCloskey, K. D., 07 Mar 2018, In: PloS one. 13, 3, 15 p., e0193923.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)194 Downloads (Pure) -
The detrusor-free bladder - it can still hold its water
McCloskey, K. D., 22 Dec 2018, (Early online date) In: The Journal of Physiology.Research output: Contribution to journal › Article › peer-review
Open AccessFile58 Downloads (Pure) -
2017
Activation of STING-Dependent Innate Immune Signaling By S-Phase-Specific DNA Damage in Breast Cancer
Parkes, E. E., Walker, S. M., Taggart, L. E., McCabe, N., Knight, L. A., Wilkinson, R., McCloskey, K., Buckley, N. E., Savage, K. I., Salto-Tellez, M., McQuaid, S., Harte, M. T., Mullan, P. B., Harkin, D. P. & Kennedy, R. D., 01 Jan 2017, In: Journal of the National Cancer Institute. 109, 1, djw199.Research output: Contribution to journal › Article › peer-review
Open AccessFile176 Citations (Scopus)763 Downloads (Pure) -
Calcium Channel Blocker Use and Risk of Prostate Cancer by TMPRSS2:ERG Gene Fusion Status
Geybels, M. S., McCloskey, K., Mills, I. G. & Stanford, J. L., 15 Feb 2017, In: Prostate. 77, 3, p. 282-290 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus)294 Downloads (Pure) -
Dual effects of radiation bystander signaling in urothelial cancer: purinergic-activation of apoptosis attenuates survival of normal and urothelial cancer cells
Bill, M., Srivastava, K., Breen, C., Butterworth, K., McMahon, S., Prise, K. & McCloskey, K., 24 Oct 2017, In: Oncotarget.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)217 Downloads (Pure) -
Exploring perceived support of postgraduate medical science research students
McEvoy, C. T., Hunter, R. F., Matchett, K. B., Carey, L., McKinley, M. C., McCloskey, K. D. & Woodside, J. V., 28 Feb 2017, (Early online date) In: Journal of Further and Higher Education. 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)343 Downloads (Pure) -
Mucosal modulation of contractility in bladder strips from normal and overactive rat models and the effect of botulinum toxin A on overactive bladder strips
Campbell, P. C., McDonnell, B., Monaghan, K. P., Baysting, L., Little, O. & McCloskey, K. D., 25 Apr 2017, In: Neurourology and Urodynamics. 36, 4, p. 1052-1060 9 p.Research output: Contribution to journal › Article
Open AccessFile4 Citations (Scopus)387 Downloads (Pure) -
2016
CaV channels and cancer: canonical functions indicate benefits of repurposed drugs as cancer therapeutics
Buchanan, P. J. & McCloskey, K., 24 Jun 2016, (Early online date) In: European biophysics journal : EBJ. 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile35 Citations (Scopus)337 Downloads (Pure) -
Vitamin D3 suppresses morphological evolution of the cribriform cancerous phenotype
Deevi, R., McClements, J., McCloskey, K. D., Fatehullah, A., Tkocz, D., Javadi, A., Higginson, R., Durban, V. M., Jansen, M., Clarke, A., Loughrey, M. & Campbell, F., 02 Aug 2016, In: Oncotarget. 7, 31, p. 49042-49064Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)406 Downloads (Pure) -
2015
The Role of Brain-Derived Neurotrophic Factor (BDNF) in the Development of Neurogenic Detrusor Overactivity (NDO)
Frias, B., Santos, J., Morgado, M., Sousa, M. M., Gray, S. M. Y., McCloskey, K., Allen, S., Cruz, F. & Cruz, C. D., 04 Feb 2015, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 35, 5, p. 2146-60 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile28 Citations (Scopus)381 Downloads (Pure) -
2014
Lamina propria: The functional center of the bladder?
Andersson, K-E. & McCloskey, K. D., Jan 2014, In: Neurourology and Urodynamics. 33, 1, p. 9-16 8 p.Research output: Contribution to journal › Article › peer-review
78 Citations (Scopus) -
Nanoencapsulation of ABT-737 and camptothecin enhances their clinical potential through synergistic antitumor effects and reduction of systemic toxicity
Schmid, D., Jarvis, G. E., Fay, F., Small, D. M., Greene, M. K., Majkut, J., Spence, S., McLaughlin, K. M., McCloskey, K. D., Johnston, P. G., Kissenpfennig, A., Longley, D. B. & Scott, C. J., 09 Oct 2014, In: Cell, Death & Disease. 5, 11 p., e1454.Research output: Contribution to journal › Article › peer-review
Open AccessFile34 Citations (Scopus)284 Downloads (Pure) -
TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities.
D'Costa, Z. C., Higgins, C., Ong, C. W., Irwin, G. W., Boyle, D., McArt, D. G., McCloskey, K., Buckley, N. E., Crawford, N. T., Thiagarajan, L., Murray, J. T., Kennedy, R. D., Mulligan, K. A., Harkin, D. P., Waugh, D. J. J., Scott, C. J., Salto-Tellez, M., Williams, R. & Mullan, P. B., 08 Feb 2014, In: Oncotarget. 5, 6, p. 1609-1620 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile27 Citations (Scopus)294 Downloads (Pure) -
2013
Bladder interstitial cells: an updated review of current knowledge
McCloskey, K., Jan 2013, In: Acta Physiologica. 207, 1, p. 7-15 9 p.Research output: Contribution to journal › Article › peer-review
39 Citations (Scopus) -
Functional expression of KCNQ (Kv7) channels in guinea-pig bladder smooth muscle and their contribution to spontaneous activity
Anderson, U. A., Carson, C., Johnston, L., Joshi, S., Gurney, A. M. & McCloskey, K. D., Jul 2013, In: British Journal of Pharmacology. 169, 6, p. 1290-1304 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile36 Citations (Scopus)273 Downloads (Pure) -
Functional innervation of Guinea-pig bladder interstitial cells of cajal subtypes: neurogenic stimulation evokes in situ calcium transients
Gray, S. M., McGeown, J. G., McMurray, G. & McCloskey, K. D., 09 Jan 2013, In: PLoS ONE. 8, 1, p. e53423Research output: Contribution to journal › Article › peer-review
Open AccessFile22 Citations (Scopus)231 Downloads (Pure) -
2012
Altered distribution of interstitial cells and innervation in the rat urinary bladder following spinal cord injury
Johnston, L., Cunningham, R. M. J., Fry, C. H., Young, J. S., McMurray, G., Eccles, R. & McCloskey, K., Jul 2012, In: Journal of Cellular and Molecular Medicine. 16, 7, p. 1533-1543 11 p.Research output: Contribution to journal › Article › peer-review
27 Citations (Scopus) -
Identification of PDGFRα Positive Populations of Interstitial Cells in Human and Guinea Pig Bladders.
Monaghan, K., Johnston, L. & McCloskey, K., Aug 2012, In: Journal of Urology. 188(2), 2, p. 639-647 9 p.Research output: Contribution to journal › Article › peer-review
34 Citations (Scopus) -
The passive and active contractile properties of the neurogenic, underactive bladder.
Young, J. S., Johnston, L., Soubrane, C., McCloskey, K., McMurray, G., Eccles, R. & Fry, C. H., 2012, In: BJU International. tbcResearch output: Contribution to journal › Article › peer-review
19 Citations (Scopus) -
2011
Calbindin 2 (CALB2) Regulates 5-Fluorouracil Sensitivity in Colorectal Cancer by Modulating the Intrinsic Apoptotic Pathway
Stevenson, L., Allen, W. L., Proutski, I., Stewart, G., Johnston, L., McCloskey, K., Wilson, P. M., Longley, D. & Johnston, P., 2011, In: PLoS ONE. 6, 5, e20276.Research output: Contribution to journal › Article › peer-review
15 Citations (Scopus) -
Interstitial Cells and Bladder Pathophysiology-Passive Bystanders or Active Participants?
McCloskey, K., May 2011, In: Journal of Urology. 185, 5, p. 1562-1563 2 p.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
Role of Delta Np63 gamma in Epithelial to Mesenchymal Transition
Lindsay, J., McDade, S., Pickard, A., McCloskey, K. & McCance, D., 04 Feb 2011, In: Journal of Biological Chemistry. 286, 5, p. 3915-3924 10 p.Research output: Contribution to journal › Article › peer-review
49 Citations (Scopus) -
The physiological properties of the decompensated, spinal cord injured bladder
Young, J., Johnston, L., McMurray, G., Eccles, R., McCloskey, K. & Fry, C., Aug 2011, In: Neurourology and Urodynamics. 30, 6, p. 932-934 3 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Ultrastructural Properties of Interstitial Cells of Cajal in the Guinea Pig Bladder
Cunningham, R., Larkin, P. & McCloskey, K., Mar 2011, In: Journal of Urology. 185, 3, p. 1123-1131 9 p.Research output: Contribution to journal › Article › peer-review
17 Citations (Scopus) -
2010
Interstitial Cells in the Urinary Bladder-Localization and Function
McCloskey, K., Jan 2010, In: Neurourology and Urodynamics. 29, 1, p. 82-87 6 p.Research output: Contribution to journal › Article › peer-review
113 Citations (Scopus) -
Morphological Expression of KIT Positive Interstitial Cells of Cajal in Human Bladder
Johnston, L., Woolsey, S., Cunningham, R., O'Kane, H., Duggan, B., Keane, P. & McCloskey, K., Jul 2010, In: Journal of Urology. 184, 1, p. 370-377 8 p.Research output: Contribution to journal › Article › peer-review
52 Citations (Scopus) -
2009
Comparison of mechanical and electrical activity and interstitial cells of Cajal in urinary bladders from wild-type and W/W-v mice
McCloskey, K., Anderson, U. A., Davidson, R. A., Bayguinov, Y. R., Sanders, K. M. & Ward, S. M., Jan 2009, In: British Journal of Pharmacology. 156, 2, p. 273-283 11 p.Research output: Contribution to journal › Article › peer-review
40 Citations (Scopus) -
KCNQ Currents and Their Contribution to Resting Membrane Potential and the Excitability of Interstitial Cells of Cajal From the Guinea Pig Bladder
Anderson, U., Carson, C. & McCloskey, K., Jul 2009, In: Journal of Urology. 182, 1, p. 330-336 7 p.Research output: Contribution to journal › Article › peer-review
41 Citations (Scopus) -
2008
Cholinergic-induced Ca2+ signaling in interstitial cells of Cajal from the guinea pig bladder.
Johnston, L., Carson, C., Lyons, A., Davidson, R. & McCloskey, K., Mar 2008, In: American Journal of Physiology - Renal Physiology. 294(3), 3, p. F645-655 11 p.Research output: Contribution to journal › Article › peer-review
50 Citations (Scopus) -
2007
Kit-positive interstitial cells in the rabbit urethra: structural relationships with nerves and smooth muscle.
Lyons, A. D., Gardiner, T. & McCloskey, K., Mar 2007, In: BJU International. 99, 3, p. 687-694 8 p.Research output: Contribution to journal › Article › peer-review
26 Citations (Scopus) -
2006
Calcium currents in interstitial cells from the guinea-pig bladder.
McCloskey, K., Jun 2006, In: BJU International. 97(6), 6, p. 1338-1343 6 p.Research output: Contribution to journal › Article › peer-review
24 Citations (Scopus) -
2005
Characterization of outward currents in interstitial cells from the guinea pig bladder.
McCloskey, K., Jan 2005, In: Journal of Urology. 173(1), 1, p. 296-301 6 p.Research output: Contribution to journal › Article › peer-review
29 Citations (Scopus) -
Mechanisms of Disease: specialized interstitial cells of the urinary tract--an assessment of current knowledge.
McCloskey, K. & Brading, A. F., Nov 2005, In: Nature clinical practice. Urology. 2(11), 11, p. 546-554 9 p.Research output: Contribution to journal › Article › peer-review
93 Citations (Scopus) -
Morphology and localization of interstitial cells in the guinea pig bladder: structural relationships with smooth muscle and neurons.
Davidson, R. A. & McCloskey, K., Apr 2005, In: Journal of Urology. 173(4), 4, p. 1385-1390 6 p.Research output: Contribution to journal › Article › peer-review
146 Citations (Scopus) -
2003
Multiphoton imaging in the detection of malignancy in the oesophagus.
Kendall, C. A., McCloskey, K., Stone, N., Barr, H. & Greenhalgh, D., 2003, In: Proc Soc Photo Opt Instrum Eng. 5139, p. 51-55 5 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
2002
Kit-like immunopositive cells in sheep mesenteric lymphatic vessels.
McCloskey, K., Hollywood, M. A., Thornbury, K. D., Ward, S. M. & McHale, N. G., 2002, In: Cell and Tissue Research. 310(1), 1, p. 77-84 8 p.Research output: Contribution to journal › Article › peer-review
76 Citations (Scopus) -
Kit positive cells in the guinea pig bladder.
McCloskey, K. & Gurney, A. M., 2002, In: Journal of Urology. 168(2), 2, p. 832-836 5 p.Research output: Contribution to journal › Article › peer-review
222 Citations (Scopus) -
WinFluor - An integrated system for the simultaneous recording of cell fluorescence images and electrophysiological signals on a single computer system.
Dempster, L., Wokosin, D. L., McCloskey, K., Girkin, J. M. & Gurney, A. M., Sep 2002, In: British Journal of Pharmacology. 137Research output: Contribution to journal › Article › peer-review
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2001
Role of IP(3) in modulation of spontaneous activity in pacemaker cells of rabbit urethra.
Sergeant, G. P., Hollywood, M. A., McCloskey, K., McHale, N. G. & Thornbury, K. D., 2001, In: American Journal of Physiology - Cell Physiology. 280(5), p. C1349-1356 8 p.Research output: Contribution to journal › Article › peer-review
92 Citations (Scopus) -
2000
Ca(2+)-activated Cl(-) current in sheep lymphatic smooth muscle.
Toland, H. M., McCloskey, K., Thornbury, K. D., McHale, N. G. & Hollywood, M. A., 2000, In: American Journal of Physiology - Cell Physiology. 279(5), p. C1327-1335 9 p.Research output: Contribution to journal › Article › peer-review
51 Citations (Scopus) -
Characterization of outward K(+) currents in isolated smooth muscle cells from sheep urethra.
Hollywood, M. A., McCloskey, K., McHale, N. G. & Thornbury, K. D., 2000, In: American Journal of Physiology - Cell Physiology. 279(2), 2 48-2, p. C420-428 9 p.Research output: Contribution to journal › Article › peer-review
19 Citations (Scopus) -
Specialised pacemaking cells in the rabbit urethra.
Sergeant, G. P., Hollywood, M. A., McCloskey, K., Thornbury, K. D. & McHale, N. G., 15 Jul 2000, In: The Journal of Physiology. 526 Pt 2, 2, p. 359-366 8 p.Research output: Contribution to journal › Article › peer-review
206 Citations (Scopus) -
1999
Hyperpolarisation-activated inward current in isolated sheep mesenteric lymphatic smooth muscle.
McCloskey, K., Toland, H., Thornbury, K. D., Hollywood, M. A. & McHale, N. G., 15 Nov 1999, In: The Journal of Physiology. 521 Pt 1, 1, p. 201-211 11 p.Research output: Contribution to journal › Article › peer-review
44 Citations (Scopus) -
1998
Enhancement of Ca2+-dependent outward current in sheep bladder myocytes by evans blue dye.
Hollywood, M. A., McCloskey, K., McHale, N. G. & Thornbury, K. D., 1998, In: Pflugers Archiv : European journal of physiology. 435(5), 5, p. 631-636 6 p.Research output: Contribution to journal › Article › peer-review
15 Citations (Scopus) -
1997
Ca2+ current and Ca(2+)-activated chloride current in isolated smooth muscle cells of the sheep urethra.
McCloskey, K., Hollywood, M. A., McHale, N. G. & Thornbury, K. D., 1997, In: The Journal of Physiology. 505 ( Pt 1), p. 121-131 11 p.Research output: Contribution to journal › Article › peer-review
48 Citations (Scopus)