• Room 03.009 - Medical Biology Centre

    United Kingdom

Accepting PhD Students

PhD projects

Title of the project: To investigate the role of the histamine four receptor in the pathogenesis of chronic lung infections.
We would like to test the hypothesis that accumulation of histamine in lung fluids impairs airways neutrophils in chronic lung diseases by engaging the histamine four receptor (H4R) in neutrophils. Engagement of the H4R may block the ability of neutrophils to kill pathogens. We will investigate whether H4R antagonists can be used to boost the anti-microbial functions of pulmonary neutrophils during chronic lung infections.

1990 …2022

Research activity per year

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Dive into the research topics where Karim Dib is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Biochemistry, Genetics and Molecular Biology

Medicine and Dentistry