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Karl Butterworth

Dr

  • Room 02.009 - CCRCB

    United Kingdom

Accepting PhD Students

PhD projects

Dr Butterworth is open to wide-ranging PhD applications from candidates with a basic science or clinical background. His fields of interest include: -Radiation Biology, Radiation Oncology and Cancer Imaging. -Nanomedicine. -Preclinical models and small animal radiotherapy. Previous research experience is desirable although not essential.

20082019

Research output per year

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Personal profile

Teaching

MED 3013 Radiobiology for Radiotherapy.

Lecturer and Joint Module Coordinator.

  • Cell Signalling and DNA Repair.
  • Radiobiological Methods.
  • Current advances in Radiation Research.

MED 3013 Preclinical Models in Cancer Research.

Lecturer and Module Coordinator.

  • Preclinical models in cancer discovery and In vitro models.
  • Modelling human cancer in mice II – Introduction to mouse genetics, genome editing technologies and genetically engineered mouse models.
  • Experimental endpoints and preclinical imaging techniques.
  • Ethics and alternatives to in vivo testing.

SCM 8066 MRes in Translational Cancer Medicine.

Lecturer.

  • Principles of Radiotherapy.
  • In vivo imaging Techniques.

BMS 2015 Biomedical Science BSc.

Lecturer.

  • Protein and Membrane Trafficking

MED 1023 Principles of Disease and Treatment 1                                               

Tutor.

  • · Problem solving with genes molecules and processes.
  • · Problems in clinical genetics.
  • · Problems in biochemical medicine.

 

Undergraduate Medicine Years 1-3 ePortfolio (UMeP)

Tutor.

BMS3012 Lab Based Honours Project in Biomedical Science         

Project Supervisor.

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Projects

R1007PMY: Anti-inflammatory radiosensitising gold nanoparticles for the treatment of prostate cancer

Coulter, J., Butterworth, K., Jain, S. & McCarthy, H.

25/01/2019 → …

Project: Research

R5051CNR: Physical and biological characterisation of clinically relevant combined MRI-radiation exposures with conventional and nanoparticle contrast agents

Prise, K. & Butterworth, K.

27/09/2017 → …

Project: Research

R1709CNR: Physical and Biological characterisation of combined MRI radiation exposures with conventional and nanoparticle contrast agents.

Prise, K. & Butterworth, K.

04/01/2017 → …

Project: Research

R2231CNR: Assessment of tumour efficacy and normal tissue toxicity using AZD6738 in combination with radiotherapy for non-small cell lung cancer

Hanna, G., Butterworth, K. & Prise, K.

01/10/2015 → 31/03/2017

Project: Research

R5885CNR: Investigation of radiobiological efficacy of cannabinol derivatives

Butterworth, K. & Prise, K.

25/09/2015 → 29/02/2016

Project: Research

Research Output

AGuIX® from bench to bedside-Transfer of an ultrasmall theranostic gadolinium-based nanoparticle to clinical medicine

Lux, F., Tran, V. L., Thomas, E., Dufort, S., Rossetti, F., Martini, M., Truillet, C., Doussineau, T., Bort, G., Denat, F., Boschetti, F., Angelovski, G., Detappe, A., Crémillieux, Y., Mignet, N., Doan, B-T., Larrat, B., Meriaux, S., Barbier, E., Roux, S. & 28 others, Fries, P., Müller, A., Abadjian, M-C., Anderson, C., Canet-Soulas, E., Bouziotis, P., Barberi-Heyob, M., Frochot, C., Verry, C., Balosso, J., Evans, M., Sidi-Boumedine, J., Janier, M., Butterworth, K., McMahon, S., Prise, K., Aloy, M-T., Ardail, D., Rodriguez-Lafrasse, C., Porcel, E., Lacombe, S., Berbeco, R., Allouch, A., Perfettini, J-L., Chargari, C., Deutsch, E., Le Duc, G. & Tillement, O., 01 Jan 2019, In : British Journal of Radiology. 92, 1093, 19 p., 20180365.

Research output: Contribution to journal › Article

Open Access
File
    • 12 Citations (Scopus)
    214 Downloads (Pure)

    Evolution of the Supermodel: Progress in Modelling Radiotherapy Response in Mice.

    Butterworth, K., 11 Mar 2019, In : Clinical oncology (Royal College of Radiologists (Great Britain)). doi: 10.1016/j.clon.2019.02.008.

    Research output: Contribution to journal › Review article

    Open Access
    File
    • 1 Citation (Scopus)
    9 Downloads (Pure)

    High-precision microbeam radiotherapy reveals testicular tissue-sparing effects for male fertility preservation

    Fukunaga, H., Kaminaga, K., Sato, T., Butterworth, K. T., Watanabe, R., Usami, N., Ogawa, T., Yokoya, A. & Prise, K. M., 01 Oct 2019, In : Scientific Reports. 9, 10 p., 12618.

    Research output: Contribution to journal › Article

    Open Access
    File
    • 67 Downloads (Pure)

    Integrating Small Animal Irradiators with Functional Imaging for Advanced Preclinical Radiotherapy Research.

    Butterworth, K., Ghita, M., Brown, K., Kelada, O. & Graves, E. E., 02 Feb 2019, In : Cancers. 11, 2

    Research output: Contribution to journal › Review article

    Open Access
    File
    • 1 Citation (Scopus)
    110 Downloads (Pure)

    Precision Radiotherapy and Radiation Risk Assessment: How Do We Overcome Radiogenomic Diversity?

    Fukunaga, H., Yokoya, A., Taki, Y., Butterworth, K. T. & Prise, K. M., 11 Apr 2019, In : The Tohoku Journal of Experimental Medicine. 247, 4, p. 223-235 13 p.

    Research output: Contribution to journal › Article

    Open Access
    File
    • 1 Citation (Scopus)
    51 Downloads (Pure)

    Prizes

    Early Career Investigator (ECI) Travel Award

    Karl Butterworth (Recipient), 23 Sep 2018

    Prize: Prize (including medals and awards)

    Early Career Investigator (ECI) Travel Award

    Karl Butterworth (Recipient), 15 Oct 2017

    Prize: Prize (including medals and awards)

    International Travel Workshop Award

    Karl Butterworth (Recipient), 01 Jun 2013

    Prize: Prize (including medals and awards)

    Michael Fry Research Award

    Karl Butterworth (Recipient), 04 Nov 2019

    Prize: Prize (including medals and awards)

    • NIH Scholarship

    Karl Butterworth (Recipient), 01 Jun 2013

    Prize: Prize (including medals and awards)

    • Activities

    Medical Research Council (External organisation)

    Karl Butterworth (Reviewer)
    24 Jan 2020

    Activity: Membership types › Membership of national or international committees and working groups

    Radiation Research Society (External organisation)

    Karl Butterworth (Member)
    01 Jan 2020 → 01 Aug 2020

    Activity: Membership types › Membership of peer review panel or committee

    Cancers (Journal)

    Karl Butterworth (Editor)
    19 Jan 2020

    Activity: Publication peer-review and editorial work types › Editorial activity

    Radiation Research Society (RRS) Annual Meeting

    Karl Butterworth (Participant)
    02 Nov 2019 → 07 Nov 2019

    Activity: Participating in or organising an event types › Participation in conference

    PhD Examiner

    Karl Butterworth (Examiner)
    10 Sep 2019

    Activity: Examination types › PhD external examination

    Thesis

    Personalised Risk Assessment of Low-dose Radiation Effects on Spermatogenesis

    Author: Fukunaga, H., Dec 2019

    Supervisor: Prise, K. (Supervisor) & Butterworth, K. (Supervisor)

    Student thesis: Doctoral Thesis › Doctor of Philosophy

    File