• Room 02.009 - CCRCB

    United Kingdom

Accepting PhD Students

PhD projects

Dr Butterworth is open to wide-ranging PhD applications from candidates with a basic science or clinical background. His fields of interest include: -Radiation Biology, Radiation Oncology and Cancer Imaging. -Nanomedicine. -Preclinical models and small animal radiotherapy. Previous research experience is desirable although not essential.

20082020

Research output per year

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Research Output

2013
45 Citations (Scopus)
2012
30 Citations (Scopus)

Cell survival responses after exposure to modulated radiation fields.

Trainor, C., Butterworth, K., McGarry, C., Liberante, F., O'Sullivan, J., Hounsell, A. & Prise, K., Jan 2012, In : Radiation Research. 177, 1, p. 44-51 8 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Cell type-dependent uptake, localization, and cytotoxicity of 1.9 nm gold nanoparticles

Coulter, J. A., Jain, S., Butterworth, K. T., Taggart, L. E., Dickson, G. R., McMahon, S. J., Hyland, W. B., Muir, M. F., Trainor, C., Hounsell, A. R., O'Sullivan, J. M., Schettino, G., Currell, F. J., Hirst, D. G. & Prise, K. M., 2012, In : International Journal of Nanomedicine. 7, null, p. 2673-2685 13 p.

Research output: Contribution to journalArticle

Open Access
File
124 Citations (Scopus)
598 Downloads (Pure)
2 Citations (Scopus)

DNA damage responses following exposure to modulated radiation fields

Trainor, C., Butterworth, K. T., McGarry, C. K., McMahon, S. J., O'Sullivan, J. M., Hounsell, A. R. & Prise, K. M., 17 Aug 2012, In : PLoS ONE. 7, 8, 13 p., e43326.

Research output: Contribution to journalArticle

Open Access
File
34 Citations (Scopus)
175 Downloads (Pure)
25 Citations (Scopus)
15 Citations (Scopus)

Physical basis and biological mechanisms of gold nanoparticle radiosensitization

Butterworth, K. T., McMahon, S. J., Currell, F. J. & Prise, K. M., 21 Aug 2012, In : Nanoscale. 4, 16, p. 4830-8 9 p.

Research output: Contribution to journalArticle

225 Citations (Scopus)

Relative biological effectiveness (RBE) and out-of-field cell survival responses to passive scattering and pencil beam scanning proton beam deliveries

Butterworth, K. T., McGarry, C. K., Clasie, B., Carabe-Fernandez, A., Schuemann, J., Depauw, N., Tang, S., McMahon, S. J., Schettino, G., O'Sullivan, J. M., Lu, H-M., Kooy, H., Paganetti, H., Hounsell, A. R., Held, K. D. & Prise, K. M., 21 Oct 2012, In : Physics in Medicine and Biology. 57, 20, p. 6671-6680 10 p., 6671.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2011

Biological consequences of nanoscale energy deposition near irradiated heavy atom nanoparticles

McMahon, S., Hyland, W., Muir, M., Coulter, J., Jain, S., Butterworth, K., Schettino, G., Dickson, G., Hounsell, A., O'Sullivan, J., Prise, K., Hirst, D. & Currell, F., 20 Jun 2011, In : Nature Scientific Reports. 1, 18.

Research output: Contribution to journalArticle

File
237 Citations (Scopus)
220 Downloads (Pure)

Energy Dependence of Gold Nanoparticle Radiosensitization in Plasmid DNA

McMahon, S., Hyland, W. B., Brun, E., Butterworth, K., Coulter, J., Douki, T., Hirst, D., Jain, S., Kavanagh, A., Krpetic, Z., Mendenhall, M. H., Muir, M. F., Prise, K., Requardt, H., Sanche, L., Schettino, G., Currell, F. & Sicard-Roselli, C., 20 Oct 2011, In : Journal of Physical Chemistry C. 115, 41, p. 20160-20167 8 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Erratum: Biological consequences of nanoscale energy deposition near irradiated heavy atom nanoparticles (Scientific Reports (2011) 1 (018) DOI:10.1038/srep00018)

McMahon, S. J., Hyland, W. B., Muir, M. F., Coulter, J. A., Jain, S., Butterworth, K. T., Schettino, G., Dickson, G. R., Hounsell, A. R., O'Sullivan, J. M., Prise, K. M., Hirst, D. G. & Currell, F. J., 20 Jun 2011, In : Scientific Reports. 3, 1725.

Research output: Contribution to journalComment/debate

Nanodosimetric effects of gold nanoparticles in megavoltage radiation therapy

McMahon, S., Hyland, W., Muir, M. F., Coulter, J., Jain, S., Butterworth, K., Schettino, G., Dickson, G., Hounsell, A., O'Sullivan, J., Prise, K., Hirst, D. & Currell, F., Sep 2011, In : Radiotherapy and Oncology. 100, 3, p. 412-416 5 p.

Research output: Contribution to journalArticle

116 Citations (Scopus)
61 Citations (Scopus)
16 Citations (Scopus)
2010
19 Citations (Scopus)

Evaluation of cytotoxicity and radiation enhancement using 1.9 nm gold particles: potential application for cancer therapy.

Butterworth, K., Jain, S., Coulter, J., Folker, J., McMahon, S., Schettino, G., Prise, K., Currell, F. & Hirst, D., Jun 2010, In : Nanotechnology. 21(29), 29, p. 295101-295110 10 p., 295101.

Research output: Contribution to journalArticle

151 Citations (Scopus)
2009

Fragmentation and plasmid strand breaks in pure and gold-doped DNA irradiated by beams of fast hydrogen atoms

Wyer, J. A., Butterworth, K., Hirst, D., Latimer, C., Montenegro, E. C., Shah, M. & Currell, F., 2009, In : Physics in Medicine and Biology. 54, 15, p. 4705-4721 17 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Variation of strand break yield for plasmid DNA irradiated with high-Z metal nanoparticles.

Butterworth, K., Wyer, J. A., Brennan-Fournet, M., Latimer, C., Shah, M., Currell, F. & Hirst, D., Sep 2008, In : Radiation Research. 170, 3, p. 381-387 7 p.

Research output: Contribution to journalArticle

64 Citations (Scopus)