Katrina Lappin

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Phone+44 (0)28 9097 2054
EmailK.Lappinqub.acuk

Room 02.012 - H.S.B
United Kingdom

Research activity per year

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10 Article
1 Abstract
1 Poster
1 Meeting abstract

13 results

2023
Combination therapies targeting apoptosis in paediatric AML: understanding the molecular mechanisms of AML treatments using phosphoproteomics
Ali, A. A., Cairns, L. V., Clarke, K. M., Blayney, J. K., Lappin, K. M. & Mills, K. I., 16 Mar 2023, In: International Journal of Molecular Sciences. 24, 6, 22 p., 5717.
Research output: Contribution to journal › Article › peer-review

Open Access
File
14 Downloads (Pure)
2022
Cancer-Associated SF3B1 Mutations Confer a BRCA-Like Cellular Phenotype and Synthetic Lethality to PARP Inhibitors
Lappin, K. M., Barros, E. M., Jhujh, S. S., Irwin, G. W., McMillan, H., Liberante, F. G., Latimer, C., LaBonte, M. J., Mills, K. I., Harkin, D. P., Stewart, G. S. & Savage, K. I., 03 Mar 2022, In: Cancer Research. 82, 5, p. 819-830 12 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
82 Downloads (Pure)
2021
Erythropoietin in bone homeostasis-Implications for efficacious anemia therapy
Lappin, K. M., Mills, K. I. & Lappin, T. R., 21 Jan 2021, (Early online date) In: Stem cells translational medicine. 8 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
53 Downloads (Pure)
Multiplex Screening for Interacting Compounds in Paediatric Acute Myeloid Leukaemia
Cairns, L. V., Lappin, K. M., Mutch, A., Ali, A., Matchett, K. B. & Mills, K. I., 21 Sep 2021, In: International Journal of Molecular Sciences. 22, 18, 19 p., 10163.
Research output: Contribution to journal › Article › peer-review

Open Access
File
65 Downloads (Pure)
2020
A compound combination screening approach with potential to identify new treatment options for paediatric acute myeloid leukaemia
Lappin, K., Davies, L., Matchett, K., Ge, Y., Mills, K. & Blayney, J., 28 Oct 2020, In: Scientific Reports. p. 18514 13 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
3 Citations (Scopus)

133 Downloads (Pure)
Chronic loss of STAG2 leads to altered chromatin structure contributiong to de-regulated transcription in AML
Smith, J., Lappin, K., Craig, S., Liberante, F., McDade, S., Thompson, A., Mills, K. & Savage, K., 03 Sep 2020, In: Journal of Translational Medicine. 18, p. 339-357 18 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
6 Citations (Scopus)

60 Downloads (Pure)
The Molecular Landscape of AML
Lappin, K., Clarke, K. & Mills, K., Jun 2020, In: HemaSphere. 4, S2, p. 112-114 3 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File

112 Downloads (Pure)
2019
Altered splicing and cytoplasmic levels of tRNA synthetases in SF3B1-mutant myelodysplastic syndromes as a therapeutic vulnerability
Liberante, F. G., Lappin, K., Barros, E. M., Vohhodina, J., Grebien, F., Savage, K. I. & Mills, K. I., 25 Feb 2019, (Early online date) In: Scientific Reports. 9, 13 p., 2678.
Research output: Contribution to journal › Article › peer-review

Open Access
File
4 Citations (Scopus)

265 Downloads (Pure)
2018
Identifying Combination Therapies Targeting Apoptosis Pathways in Pediatric Acute Myeloid Leukemia (CAuSAL Study)
Lappin, K., Matchett, K., Blayney, J. & Mills, K., 2018.
Research output: Contribution to conference › Abstract › peer-review
2017
Integrated analysis of the molecular action of Vorinostat identifies epi-sensitised targets for combination therapy
Hay, J. F., Lappin, K., Liberante, F., Kettyle, L. M., Matchett, K. B., Thompson, A. & Mills, K. I., 01 Jul 2017, In: Oncotarget. 8, 40, p. 67891-67903 13 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
2 Citations (Scopus)

233 Downloads (Pure)
Polycomb protein RING1A limits hematopoietic differentiation in myelodysplastic syndromes
Palau, A., Garz, A. K., Diesch, J., Zwick, A., Malinverni, R., Valero, V., Lappin, K., Casquero, R., Lennartsson, A., Zuber, J., Navarro, T., Mills, K. I., Götze, K. S. & Buschbeck, M., 01 Dec 2017, In: Oncotarget. 8, 70, p. 115002-115017 16 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
4 Citations (Scopus)

237 Downloads (Pure)
2015

The molecular and therapeutic relevance of SF3B1 in myelodysplastic syndrome
Lappin, K. M., Liberante, F. G., Savage, K. I. & Mills, K. I., 19 Apr 2015, p. 87. 1 p.
Research output: Contribution to conference › Poster › peer-review
The molecular and therapeutic relevance of SF3B1 in myelodysplastic syndrome
Lappin, K. M., Liberante, F. G., Savage, K. I. & Mills, K. I., 19 Apr 2015, In: British Journal of Haematology. 169, Supplement s1, p. 87 1 p.
Research output: Contribution to journal › Meeting abstract › peer-review

Katrina Lappin

Research output

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