Photo of Keara Redmond

Keara Redmond

Dr

  • Room 03.006 - CCRCB

    United Kingdom

20102019
If you made any changes in Pure these will be visible here soon.

Research Output 2010 2019

  • 7 Article
  • 4 Conference contribution
2019
1 Citation (Scopus)
79 Downloads (Pure)
Open Access
File
Tumor Microenvironment
Colorectal Neoplasms
Fibroblasts
Epithelial Cells
Bone Morphogenetic Proteins
2016
51 Citations (Scopus)

EphA2 Expression Is a Key Driver of Migration and Invasion and a Poor Prognostic Marker in Colorectal Cancer

Dunne, P. D., Dasgupta, S., Blayney, J. K., McArt, D. G., Redmond, K. L., Weir, J-A., Bradley, C. A., Sasazuki, T., Shirasawa, S., Wang, T., Srivastava, S., Ong, C. W., Arthur, K., Salto-Tellez, M., Wilson, R. H., Johnston, P. G. & Van Schaeybroeck, S., 01 Jan 2016, In : Clinical Cancer Research. 22, 1, p. 230-242 13 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
EphA2 Receptor
Eph Family Receptors
Cell Line
Neoplasms
2015
28 Citations (Scopus)

Overcoming Resistance to Targeted Therapies in Cancer

Redmond, K. L., Papafili, A., Lawler, M. & Van Schaeybroeck, S., Dec 2015, In : Seminars in Oncology. 42, 6, p. 896-908 13 p.

Research output: Contribution to journalArticle

Neoplasms
Therapeutics
Precision Medicine
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Disease Progression

The role of micro-environment-derived ligands in resistance to EGFR monoclonal antibodies in KRAS wild type colorectal cancer

Weir, J-A., Redmond, K., Bradley, C. & Van Schaeybroeck, S., Nov 2015, The role of micro-environment-derived ligands in resistance to EGFR monoclonal antibodies in KRAS wild type colorectal cancer. National Cancer Research Institute, Vol. A87.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2014
47 Citations (Scopus)
295 Downloads (Pure)

ADAM17-Dependent c-MET-STAT3 Signaling Mediates Resistance to MEK Inhibitors in KRAS Mutant Colorectal Cancer

Van Schaeybroeck, S., Kalimutho, M., Dunne, P. D., Carson, R., Allen, W., Jithesh, P. V., Redmond, K. L., Sasazuki, T., Shirasawa, S., Blayney, J., Michieli, P., Fenning, C., Lenz, H-J., Lawler, M., Longley, D. B. & Johnston, P. G., 26 Jun 2014, In : Cell Reports. 7, 6, p. 1940-1955 16 p.

Research output: Contribution to journalArticle

Open Access
File
Mitogen-Activated Protein Kinase Kinases
Colorectal Neoplasms
Chemical activation
Systems Biology
Metalloproteases
59 Citations (Scopus)

AXL Is a Key Regulator of Inherent and Chemotherapy-Induced Invasion and Predicts a Poor Clinical Outcome in Early-Stage Colon Cancer

Dunne, P. D., McArt, D. G., Blayney, J. K., Kalimutho, M., Greer, S., Wang, T., Srivastava, S., Ong, C. W., Arthur, K., Loughrey, M., Redmond, K., Longley, D. B., Salto-Tellez, M., Johnston, P. G. & Van Schaeybroeck, S., 01 Jan 2014, In : Clinical Cancer Research. 20, 1, p. 164-175 12 p.

Research output: Contribution to journalArticle

Colonic Neoplasms
Colorectal Neoplasms
Drug Therapy
Receptor Protein-Tyrosine Kinases
Epidermal Growth Factor Receptor

The Role of the c-MET/HGF Signalling Axis as a Critical Regulator of Invasion and Migration in Colorectal Cancer

Bradley, C., Dunne, P., Redmond, K., McArt, D., Arthur, K., McQuaid, S., Blayney, J., Salto-Tellez, M., Johnston, P. & Van Schaeybroeck, S., Nov 2014, The Role of the c-MET/HGF Signalling Axis as a Critical Regulator of Invasion and Migration in Colorectal Cancer. National Cancer Research Institute

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hepatocyte Growth Factor
Colorectal Neoplasms
Tumor Microenvironment
Coculture Techniques
Cell Line

The role of the inflammatory microenvironment in regulating invasion, migration and drug responses in colorectal cancer

Redmond, K., Dunne, P., Forsythe, N., Longley, D., Johnston, P. & Van Schaeybroeck, S., Nov 2014, The role of the inflammatory microenvironment in regulating invasion, migration and drug responses in colorectal cancer. National Cancer Research Institute

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2013

Oncogenic Kras and p53 mutational status control chemotherapy-induced growth factor shedding via activation of ADAM17 in colorectal cancer

Redmond, K., Dunne, P., McArt, D., Longley, D., Johnston, P. & Van Schaeybroeck, S., Nov 2013, Oncogenic Kras and p53 mutational status control chemotherapy-induced growth factor shedding via activation of ADAM17 in colorectal cancer. National Cancer Research Institute

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2012
57 Citations (Scopus)

Identification of an acetylation-dependant Ku70/FLIP complex that regulates FLIP expression and HDAC inhibitor-induced apoptosis

Kerr, E., Holohan, C., McLaughlin, KM., Majkut, J., Dolan, S., Redmond, K., Riley, J., McLaughlin, K., Stasik, I., Crudden, M., Van Schaeybroeck, S., Fenning, C., O'Connor, R., Kiely, P., Sgobba, M., Haigh, D., Johnston, PG. & Longley, DB., Aug 2012, In : Cell Death and Differentiation. 19, 8, p. 1317-1327 11 p., e1745.

Research output: Contribution to journalArticle

Histone Deacetylase Inhibitors
Caspase 8
Protein Stability
Acetylation
Apoptosis
2010
42 Citations (Scopus)

T-box 2 represses NDRG1 through an EGR1-dependent mechanism to drive the proliferation of breast cancer cells

Redmond, K. L., Crawford, N., Farmer, H., D'Costa, Z. C., O'Brien, G. J., Buckley, N., Kennedy, R., Johnston, P., Harkin, P. & Mullan, P., 03 Jun 2010, In : Oncogene. 29, 22, p. 3252-3262 11 p.

Research output: Contribution to journalArticle

myc Genes
Down-Regulation
Breast Neoplasms
Growth
Breast