• Room 02.003 - CCRCB

    United Kingdom

Accepting PhD Students

1986 …2020

Research output per year

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Personal profile

Research Interests

Kevin Prise is Professor of Radiation Biology, Queen’s University Belfast, where he has been since 2007. Prior to this, he was Head of the Cell and Molecular Radiation Biology Group at the Gray Cancer Institute in Northwood, London. A Biochemistry graduate of Aberdeen University, he received his PhD in Cell Biology and Biochemistry, from the University of Aberdeen, on the mechanisms of action of the chemotherapeutic methotrexate. He joined the Gray Laboratory in 1985 working with Barry Michael, Melvyn Folkard and Boris Vojnovic, under the directorship of Jack Fowler, Julie Denekamp and Ged Adams.

He has developed wide-ranging interests in radiation biology including research on low dose radiation risk, radiation quality, cell and tissue signalling mechanisms. He has played a major role in the application of microbeam technologies for delineating the response of cells to targeted single tracks of radiation. His seminal work defined the impact of bystander signalling after targeted irradiation and its implications for future advanced radiotherapy where immune signalling and abscopal responses have significant potential. His recent work, at Queen’s has involved the development of an Advanced Radiotherapy Group (ARG) integrating Radiation Oncology, under the leadership of Professor Joe O’Sullivan, and Clinical Radiotherapy Physics, under the leadership of Professor Alan Hounsell, with translational radiation biology.  Together they are developing new biological based models for optimising advanced radiotherapies such as Intensity Modulated Radiotherapy and particle therapies. A current focus is the application of radionuclide approaches in advanced prostate cancer.

He is currently Immediate Past-President of the US Radiation Research Society, a previous RRS Michael Fry award recipient and Friedrich Dessauer awardee of the German Radiation Research Societies. He was the 2018 Douglas Lea Lecturer, awarded by the Institute of Physics and Engineering in Medicine and the 2018 Bacq and Alexander awardee from the European Radiation Research Society. He has recently served on the UK Government Expert Committee on Medical Aspects of Radiation in the Environment (COMARE) and is currently Editor in Chief (Scientific) of the British Journal of Radiology.  He has supervised over 45 PhD students and numerous Master and undergraduate students. He has taught on the FRCR Part 1 course at the Christie Hospital for the last 12 years and also launched this course internationally with Prof Catharine West in Kolkata, India in 2015 and Kuala Lumpur, Malaysia in 2017. He is a previous part 1 examiner for the Royal College of Radiologists and a current honorary member. He has published over 315 papers (h=57), with over 10,000 citations.

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Projects

Research Output

125 years of BJR and radiological research: a celebration of the world's oldest radiology journal

Jackson, S. A. & Prise, K. M., 01 Jan 2020, In : British Journal of Radiology. 93, 1105, 20209001.

Research output: Contribution to journalEditorial

Open Access
File
16 Downloads (Pure)

AGuIX® from bench to bedside-Transfer of an ultrasmall theranostic gadolinium-based nanoparticle to clinical medicine

Lux, F., Tran, V. L., Thomas, E., Dufort, S., Rossetti, F., Martini, M., Truillet, C., Doussineau, T., Bort, G., Denat, F., Boschetti, F., Angelovski, G., Detappe, A., Crémillieux, Y., Mignet, N., Doan, B-T., Larrat, B., Meriaux, S., Barbier, E., Roux, S. & 28 others, Fries, P., Müller, A., Abadjian, M-C., Anderson, C., Canet-Soulas, E., Bouziotis, P., Barberi-Heyob, M., Frochot, C., Verry, C., Balosso, J., Evans, M., Sidi-Boumedine, J., Janier, M., Butterworth, K., McMahon, S., Prise, K., Aloy, M-T., Ardail, D., Rodriguez-Lafrasse, C., Porcel, E., Lacombe, S., Berbeco, R., Allouch, A., Perfettini, J-L., Chargari, C., Deutsch, E., Le Duc, G. & Tillement, O., 01 Jan 2019, In : British Journal of Radiology. 92, 1093, 19 p., 20180365.

Research output: Contribution to journalArticle

Open Access
File
  • 12 Citations (Scopus)
    214 Downloads (Pure)

    Clinically Actionable Insights into Initial and Matched Recurrent Glioblastomas to Inform Novel Treatment Approaches

    Ellis, H. P., McInerney, C. E., Schrimpf, D., Sahm, F., Stupnikov, A., Wadsley, M., Wragg, C., White, P., Prise, K. M., McArt, D. G. & Kurian, K. M., 31 Dec 2019, In : Journal of Oncology. 2019, p. 4878547

    Research output: Contribution to journalArticle

    Open Access
    File
  • 32 Downloads (Pure)
  • Diversity of ATM gene variants: a population-based genome data analysis for precision medicine

    Fukunaga, H., Taki, Y. & Prise, K. M., 23 Aug 2019, In : Human genomics. 13, 1, p. 38

    Research output: Contribution to journalArticle

    Open Access
    File
  • 83 Downloads (Pure)

    Prizes

    European Radiation Research Society: 2018 Bacq and Alexander Award

    Kevin Prise (Recipient), 22 Aug 2018

    Prize: Prize (including medals and awards)

  • Friedrich-Dessaur Prize -Association of Radiation Research Societies in Germany

    Kevin Prise (Recipient), 28 Feb 2001

    Prize: Prize (including medals and awards)

  • Honorary Membership Royal College of Radiologists

    Kevin Prise (Recipient), 2017

    Prize: National/international honour

    Institute of Physics & Engineering in Medicine 2018 Douglas Lea Lecture

    Kevin Prise (Recipient), 04 Jul 2018

    Prize: National/international honour

    Activities

    • 6 Contribution to the work of national or international committees and working groups
    • 1 Editorial activity
    • 1 Membership of board

    President - US Radiation Research Society

    Kevin Prise (Board Member)
    01 Sep 201730 Sep 2018

    Activity: Consultancy typesContribution to the work of national or international committees and working groups

    Vice-President US Radiation Research Society

    Kevin Prise (Board Member)
    01 Sep 201631 Aug 2017

    Activity: Consultancy typesContribution to the work of national or international committees and working groups

    Vice-President Elect US Radiation Research Society

    Kevin Prise (Board Member)
    01 Sep 201531 Aug 2016

    Activity: Consultancy typesContribution to the work of national or international committees and working groups

    LH Gray Memorial Trust (External organisation)

    Kevin Prise (Board Member)
    2015 → …

    Activity: Membership typesMembership of board

    Member of UK Department of Health expert Committee on Medical Aspects of Radiation in the Environment (COMARE)

    Kevin Prise (Member)
    01 Jul 201530 Jun 2018

    Activity: Consultancy typesContribution to the work of national or international committees and working groups

    Press / Media

    Tumour growth models shed light on radionuclide therapy

    Kevin Prise, Francisco Liberal, Joseph O'Sullivan, Stephen McMahon & Hugo Moreira

    06/03/2019

    1 Media contribution

    Press/Media: Research

    Thesis

    Laser-Driven Acceleration of Ions: Biological Effects at Ultra-High Dose Rates

    Author: Gwynne, D., Jul 2018

    Supervisor: Borghesi, M. (Supervisor) & Prise, K. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy

    File

    Personalised Risk Assessment of Low-dose Radiation Effects on Spermatogenesis

    Author: Fukunaga, H., Dec 2019

    Supervisor: Prise, K. (Supervisor) & Butterworth, K. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy

    File

    The Role of c-FLIP in Regulating Resistance to Ionizing Radiation

    Author: McLaughlin, K. A. J., Jul 2016

    Supervisor: Longley, D. (Supervisor) & Prise, K. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy

    File