Projects per year
Personal profile
Research Interests
Kevin Prise is Emeritus Professor of Radiation Biology, at the Johnston Cancer Research Centre (JCRC), Queen’s University Belfast, where he has been since 2007. Prior to this, he was Head of the Cell and Molecular Radiation Biology Group at the Gray Cancer Institute in Northwood, London. A Biochemistry graduate of Aberdeen University, he received his PhD in Cell Biology and Biochemistry, from the University of Aberdeen, on the mechanisms of action of the chemotherapeutic methotrexate. He joined the Gray Laboratory in 1985 working with Barry Michael, Melvyn Folkard and Boris Vojnovic, under the directorships of Jack Fowler, Julie Denekamp and Ged Adams. In 2007 he was recruited by Professor Paddy Johnston to setup a Translational Radiation Biology program at the newly opened Centre for Cancer Research and Cell Biology (now JCRC) at Queen's University Belfast. He served as Deputy Director of the Centre from 2010 to 2018 under the directorships of Professor Dennis McCance and then Professor David Waugh.
He has developed wide-ranging interests in radiation biology including research on low dose radiation risk, radiation quality, cell and tissue signalling mechanisms. He has played a major role in the application of microbeam technologies for delineating the response of cells to targeted single tracks of radiation. His seminal work defined the impact of bystander signalling after targeted irradiation and its implications for future advanced radiotherapy where immune signalling and abscopal responses have significant potential. At Queen’s he developed an Advanced Radiotherapy Group (ARG) integrating Radiation Oncology, under the leadership of Professor Joe O’Sullivan, and Clinical Radiotherapy Physics, under the leadership of Professor Alan Hounsell, with translational radiation biology. Together they are developing new biological based models for optimising advanced radiotherapies such as Intensity Modulated Radiotherapy and particle therapies. A current focus is the application of radionuclide approaches in advanced prostate cancer.
He is a Past-President of the US Radiation Research Society (RRS), a previous RRS Michael Fry award recipient and Friedrich Dessauer awardee of the German Radiation Research Societies. He was inducted as a Fellow of the RRS in 2025. He was the 2024 recipient of the Weiss Medal from the UK Association for Radiation Research, the 2018 Douglas Lea Lecturer, awarded by the Institute of Physics and Engineering in Medicine and the 2018 Bacq and Alexander awardee from the European Radiation Research Society. He has recently served on the UK Government Expert Committee on Medical Aspects of Radiation in the Environment (COMARE) and previously Editor in Chief (Scientific) of the British Journal of Radiology. He has supervised over 50 PhD students and numerous Masters and undergraduate students. He has taught on the FRCR Part 1 course at the Christie Hospital for the last 15 years and also launched this course internationally with Prof Catharine West in Kolkata, India in 2015 and Kuala Lumpur, Malaysia in 2017. He is a previous Part 1 examiner for the Royal College of Radiologists and a current Honorary Member. He has published over 400 papers (h=75), with over 18,000 citations.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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R6633CNR: ORIGIN: Optical fibRe dose ImaGINg for adaptive brachytherapy
Prise, K. (PI) & Jain, S. (CoI)
11/11/2019 → …
Project: Research
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R9247CNR: PARADIGM data analytics for information discovery
McArt, D. (CoI) & Prise, K. (CoI)
05/11/2018 → …
Project: Research
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R2459CNR: Clinical Research Fellowship in Radiotherapy
O'Sullivan, J. (PI), Cole, A. (CoI), McCloskey, K. (CoI) & Prise, K. (CoI)
05/03/2018 → …
Project: Research
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R2529CNR: Role of PTEN in regulating IR-induced CXC-chemokine signalling and it's importance
Waugh, D. (PI) & Prise, K. (CoI)
01/08/2009 → …
Project: Research
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R2336CNR: The BRCA/FA network in the radiation-induced DNA
Prise, K. (PI)
01/08/2009 → …
Project: Research
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Impact of ataxia-telangiectasia mutated (ATM) loss on radiobiological and immune response to radium-223 in prostate cancer in vitro models
Dunne, V. L., Wright, T. C., Toner, A., Wilson, M. L., Savage, K. I., O'Sullivan, J. M. & Prise, K. M., 01 Jul 2026, In: Clinical and Translational Radiation Oncology. 59, 7 p., 101206.Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Downloads (Pure) -
Investigation of image-guided in vivo irradiation on voiding patterns and bladder contractility in female mice
McDowell, S., Breen, C., McKerr, N., Srivastava, K., Crummey, D., Ghita-Pettigrew, M., Butterworth, K. T., O'Sullivan, J. M., Prise, K. M. & McCloskey, K. D., 06 Jan 2026, In: Scientific Reports. 16, 13 p., 518.Research output: Contribution to journal › Article › peer-review
Open AccessFile25 Downloads (Pure) -
Longitudinal analysis of male fertility using an Acr-Luc knock-in mouse model: a preclinical platform for reproductive toxicity testing
Fukunaga, H., Seino, R., Matsuya, Y., Takashima, H., Ishikawa, M., Onodera, Y., Shirato, H., Miyata, H. & Prise, K. M., 01 Jan 2026, In: MedComm. 7, 1, 11 p., e70568.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Link opens in a new tab Citation (Scopus)29 Downloads (Pure) -
Refining photon- and particle-induced chromosome aberration predictions for simplified and detailed radiation damage models
Thompson, S. J., Prise, K. M. & McMahon, S. J., 14 Apr 2026, In: Physics in Medicine and Biology. 71, 7, 16 p., 075014.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Downloads (Pure) -
Rethinking tissue reactions to radiation exposure: The tissue-sparing effect as a threshold for radiation-induced male infertility
Fukunaga, H. & Prise, K. M., 28 May 2026, (Early online date) In: Annals of the ICRP.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Downloads (Pure)
Datasets
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Dataset for "Cellular irradiations with laser-driven carbon ions at ultra-high dose rates"
Chaudhary, P. (Creator), Borghesi, M. (Supervisor), Prise, K. (Supervisor), Ahmed, H. (Contributor), Doria, D. (Contributor), McIlvenny, A. (Contributor) & Romagnani, L. (Contributor), Queen's University Belfast, 20 Dec 2022
DOI: 10.17034/642ccd19-b32c-4682-809f-4f34a91c8d94
Dataset
File
Prizes
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Elected Fellow of the British Institute of Radiology (FBIR)
Prise, K. (Recipient), 01 Oct 2020
Prize: National/international honour
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European Radiation Research Society: 2018 Bacq and Alexander Award
Prise, K. (Recipient), 22 Aug 2018
Prize: Prize (including medals and awards)
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Fellow of the Radiation Research Society (FRRS)
Prise, K. (Recipient), 23 Sept 2025
Prize: National/international honour
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Friedrich-Dessaur Prize -Association of Radiation Research Societies in Germany
Prise, K. (Recipient), 28 Feb 2001
Prize: Prize (including medals and awards)
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Honorary Membership Royal College of Radiologists (MRCR)
Prise, K. (Recipient), 2017
Prize: National/international honour
Activities
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John Kildea
Prise, K. (Host)
23 Sept 2024 → 22 Aug 2025Activity: Hosting a visitor types › Hosting an academic visitor
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Pietro Pisciotta
Prise, K. (Host)
01 Sept 2018 → 31 Aug 2019Activity: Hosting a visitor types › Hosting an academic visitor
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President - US Radiation Research Society
Prise, K. (Board Member)
01 Sept 2017 → 30 Sept 2018Activity: Consultancy types › Contribution to the work of national or international committees and working groups
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Vice-President US Radiation Research Society
Prise, K. (Board Member)
01 Sept 2016 → 31 Aug 2017Activity: Consultancy types › Contribution to the work of national or international committees and working groups
Press/Media
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Tumour growth models shed light on radionuclide therapy
Prise, K., Liberal, F., O'Sullivan, J., McMahon, S. & Moreira, H.
06/03/2019
1 Media contribution
Press/Media: Research
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Radiosensitivity model addresses personalized therapy
McMahon, S., McNamara, A. L., Schuemann, J., Paganetti, H. & Prise, K.
06/10/2017
1 item of Media coverage
Press/Media: Research
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Radiosensitization: which element is optimal?
McMahon, S., Paganetti, H. & Prise, K.
10/02/2016
1 item of Media coverage
Press/Media: Research