Projects per year
Personal profile
Research Interests
Genetics, Epigenetics, Genomics, Transcriptomics, DNA Methylation, Bioinformatics, Kidney Disease, Renal Disease, Complex Diseases, Chronic Diseases, Healthy Ageing,
Teaching
- BMS2111 - Clinical Genetics, module co-ordinator (2024-Present)
- BMS1105 - Professional Skills for Scientists, mentor (2023-Present)
- BMS2102 - Professional Skills for Scientists, mentor (2023-Present)
- SCM8102 - Public Health Genetics Lecture (2021)
- SCM8095 - Genomics and Human Disease, designed and delivered several classes (2017-Present)
- BMS3112 - The Research Project, supervisor (2015-Present)
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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SDG 4 Quality Education
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SDG 10 Reduced Inequalities
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SDG 11 Sustainable Cities and Communities
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SDG 17 Partnerships for the Goals
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Collaborations and top research areas from the last five years
Projects
- 2 Active
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R5299CPH: Innovative multi-omics approaches to improve detection, diagnosis and prognosis of medical conditions and complications arising from metabolic syndrome
Smyth, L. (PI), McKay, G. (CoI) & McKnight, A. J. (CoI)
20/03/2024 → …
Project: Research
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R1267CPH: Transforming Diabetic Kidney Disease Care: Harnessing Integrative Multi-Omics Analysis for Precision Diagnosis and Management
McKay, G. (PI), Hill, C. (CoI), McKnight, A. J. (CoI) & Smyth, L. (CoI)
14/11/2023 → …
Project: Research
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Baseline epigenetic clock measures in the Northern Ireland Cohort for the Longitudinal Study of Ageing (NICOLA)
Hill, C., Potter, C., Smyth, L., Kilner, J., Scott, A., Neville, C., Kee, F., McGuinness, B. & McKnight, A. J., 28 Apr 2026, In: BMC Research Notes. 19, 1, 4 p., 192.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Downloads (Pure) -
Blood DNA methylation markers are associated with diabetic kidney disease progression in type 1 diabetes
Syreeni, A., Dahlström, E. H., Smyth, L. J., Hill, C., Mutter, S., Harjutsalo, V., Chen, Z., Natarajan, R., Krolewski, A., Hirschhorn, J. N., Florez, J. C., Consortium, G., Maxwell, A. P., Groop, P.-H., McKnight, A. J., Sandholm, N. & The FinnDiane Study Group, May 2026, In: Diabetologia. 69, 5, p. 1317-1336 20 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Link opens in a new tab Citation (Scopus)29 Downloads (Pure) -
Exome-wide analysis identifies a rare EXD3 missense variant associated with diabetic kidney disease
Sandholm, N., Cole, J. B., Nair, V., Brennan, E., Giardini, E., Haukka, J. K., Ha, E., Syreeni, A., Dahlström, E. H., Salem, R. M., Fermin, D., Mercader, J., Smyth, L., Hill, C., Mychaleckyj, J., McGurnaghan, S., Miller, R. G., Costacou, T., Klein, B. E. K. & Snell-Bergeon, J. & 27 others, , Jan 2026, In: Kidney International Reports. 11, 1, p. 219-232 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Link opens in a new tab Citations (Scopus)19 Downloads (Pure) -
Physiological health Age (PhysAge): A novel multi-system molecular timepiece predicts health and mortality in older adults
Arpawong, T. E., Hernández, B., Potter, C., Leigh, R. J., Klopak, E. T., Hill, C., Fiorito, G., Smyth, L., O'Halloran, A. M., McGuinness, B., Faul, J. D., Kenny, R. A., McKnight, A. J., Crimmins, E. M. & McCrory, C., Apr 2026, In: GeroScience. 48, p. 3115–3135Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Link opens in a new tab Citations (Scopus)168 Downloads (Pure) -
Response to the letter to the editor entitled “A missing genomic dimension: the small but central mitochondrial genome in diabetic kidney disease genetics”
Sandholm, N., Cole, J. B., Nair, V., Brennan, E., Giardini, E., Haukka, J. K., Ha, E., Syreeni, A., Dahlström, E. H., Salem, R. M., Fermin, D., Mercader, J., Smyth, L., Hill, C., Mychaleckyj, J., McGurnaghan, S., Miller, R. G., Costacou, T., Snell-Bergeon, J. & Paterson, A. D. & 19 others, , Jul 2026, In: Kidney International Reports. 11, 7, 106572.Research output: Contribution to journal › Letter › peer-review
Open AccessFile
Prizes
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European Diabetic Nephropathy Study Group (EDNSG) Rising Star Award
Smyth, L. (Recipient), 26 May 2023
Prize: Prize (including medals and awards)
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Finalist, Vice Chancellor's Research Culture Prize 2020
McKnight, A. J. (Recipient), Smyth, L. (Recipient), Cañadas Garre, M. (Recipient), McMullan, J. (Recipient), Kerr, K. (Recipient), Anderson, K. (Recipient), Bailie, C. (Recipient), Potter, C. (Recipient), Crowe, A. (Recipient), Watt, P. (Recipient) & Kilner, J. (Recipient), Dec 2020
Prize: Prize (including medals and awards)
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QUB Staff Excellence Awards: shortlisted for Making a Difference 2022 (awarded 2023)
McKnight, A. J. (Recipient), Kilner, J. (Recipient), Smyth, L. (Recipient), Hill, C. (Recipient) & Kerr, K. (Recipient), 17 Feb 2023
Prize: Prize (including medals and awards)
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QUB Staff Excellence Awards: shortlisted for Team of the Year 2019 (awarded 2020)
McKnight, A. J. (Recipient), Maxwell, P. (Recipient), Kee, F. (Recipient), Smyth, L. (Recipient), McMullan, J. (Recipient), Cañadas Garre, M. (Recipient), McAneney, H. (Recipient), Kilner, J. (Recipient), Wooster, C. (Recipient), Kerr, K. (Recipient), Crowe, A. (Recipient), Bailie, C. (Recipient), Anderson, K. (Recipient), Cappa, R. (Recipient) & Skelly, R. (Recipient), 07 Feb 2020
Prize: Prize (including medals and awards)
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Recipient of a QUB staff recognition scheme (STAR) award
Smyth, L. (Recipient), Jul 2020
Prize: Prize (including medals and awards)
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Belfast Healthy Cities
Hill, C. (Contributor), Smyth, L. (Contributor), Abdelrahman, Z. (Contributor), Quinn, K. (Contributor), Dealey, C. (Contributor), Surridge-Smith, M. (Contributor), Walsh, S. (Contributor), Glover, S. (Contributor), Illyuk, J. (Contributor), McKnight, A. J. (Contributor) & Hunter, R. (Organiser)
12 May 2026Activity: Participating in or organising an event types › Participation in Festival/Exhibition
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Show Your Kidneys Some Love @ Love Your Health – Northern Ireland Science Festival
Hill, C. (Organiser), Kee, S. (Organiser), McKnight, A. J. (Organiser), Quinn, K. (Member of the organising committee), Abdelrahman, Z. (Member of the organising committee), Jeyaraj, P. (Member of the organising committee), Wooster, C. (Member of the organising committee), Montgomery, R. (Member of the organising committee), Brown, H. (Member of the organising committee), Kilner, J. (Member of the organising committee), Smyth, L. (Member of the organising committee) & Azam, O. (Member of the organising committee)
14 Feb 2026Activity: Participating in or organising an event types › Participation in Festival/Exhibition
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The impact of accelerated epigenetic ageing in the NICOLA study
Hill, C. (Invited speaker), Potter, C. (Contributor), Smyth, L. (Contributor), McGuinness, B. (Contributor), Maxwell, P. (Contributor), McKay, G. (Contributor) & McKnight, A. J. (Contributor)
16 Sept 2025Activity: Talk or presentation types › Invited talk
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Kidney Canvas
Hill, C. (Organiser), McKnight, A. J. (Member of the organising committee), Noble, H. (Member of the organising committee), Forbes, T. (Member of the organising committee), Smyth, L. (Member of the organising committee), Wilson, A. (Member of the organising committee), Quinn, K. (Member of the organising committee), Gupta, Y. (Member of the organising committee), Abdelrahman, Z. (Member of the organising committee), Walsh, I. (Member of the organising committee), McKeaveney, C. (Member of the organising committee) & Coulter, T. (Member of the organising committee)
18 Feb 2024Activity: Participating in or organising an event types › Participation in Festival/Exhibition
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My journey exploring the dynamic world of epigenetics in diabetic kidney disease
Smyth, L. (Invited speaker)
26 May 2023Activity: Talk or presentation types › Invited talk