Projects per year
Personal profile
Research Focus
Linda obtained both her BSc (Joint Honours) in Genetics and Microbiology (1987) and her PhD in Clinical Microbiology (1993) at Queen's University Belfast. Her PhD was based on the gut bacterium Bacteroides fragilis and investigations of its antigenic variation in clinical samples. She completed her PhD on a part time basis while employed full time as a Senior Biomedical Scientist in the Microbiology department at Craigavon Area Hospital Group Trust before returning to research at Queen’s in 2005. As a post-doctoral researcher she worked on a number of projects producing novel binders and using these to develop new technologies for the detection of harmful contaminants in food. In 2012 she was appointed as a part-time lecturer in Microbiology which was converted to a full time position in 2015. Her research at QUB focuses on: biomarker discovery; binder generation, characterisation and mapping, including monoclonal and polyclonal antibodies, phage display derived binders, scFv antibodies; epitope mapping; and immunodiagnostic assay development and validation using a range of platforms from the research laboratory to the commercial market. She has maintained her interest in the human microbiome and is involved in research into bacterial pathogenesis and antimicrobial resistance. Key achievements include production of an anti-toxin antibody currently used in a commercially available diagnostic assay, and development of a unique novel immunodiagnostic assay capable of differentiating Mycobacterium bovis from Mycobacterium tuberculosis. She is also currently mapping epitopes on a recently identified ubiquitin like protein isolated from Bacteroides fragilis.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Projects
- 1 Finished
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R1825GFS: Serological detection of Tuberculosis infection using novel phage display-derived peptides
Stewart, L. (PI) & Grant, I. R. (CoI)
16/10/2017 → 30/06/2019
Project: Research
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Culture of Mycobacterium avium subsp. paratuberculosis: challenges, limitations and future prospects
Dane, H., Stewart, L. D. & Grant, I. R., 02 Jan 2023, In: Journal of Applied Microbiology. 134, 1, 11 p., lxac017.Research output: Contribution to journal › Review article › peer-review
Open AccessFile9 Citations (Scopus)73 Downloads (Pure) -
Genomic analyses of Bacteroides fragilis: subdivisions I and II represent distinct species
English, J., Newberry, F., Hoyles, L., Patrick, S. & Stewart, L., 01 Nov 2023, In: Journal of Medical Microbiology. 72, 11, 15 p., 001768.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)127 Downloads (Pure) -
Increased intestinal permeability: an avenue for the development of autoimmune disease?
English, J., Connolly, L. & Stewart, L. D., 19 Jun 2023, (Early online date) In: Exposure and Health. 31 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile3 Citations (Scopus)64 Downloads (Pure) -
Smartphone-based immunochemical sensor exploiting peroxidase-like activity of ligand-capped gold nanostars: a proof-of-concept detection of Mycobacterium bovis
Lou-Franco, J., Zhao, Y., Neils, J. L. D., Stewart, L., Rafferty, K., Elliott, C. & Cao, C., 15 Jan 2023, In: Biosensors and Bioelectronics. 220, 10 p., 114857.Research output: Contribution to journal › Article › peer-review
Open AccessFile22 Citations (Scopus)103 Downloads (Pure) -
The potential role of molecular mimicry by the anaerobic microbiota in the aetiology of autoimmune disease
English, J., Patrick, S. & Stewart, L. D., Apr 2023, In: Anaerobe. 80, 9 p., 102721.Research output: Contribution to journal › Review article › peer-review
Open AccessFile10 Citations (Scopus)75 Downloads (Pure)
Datasets
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Dataset for "Variations in the properties of dairy cow manure – implications for the testing and efficacy of footbathing products
Palmer, M. (Creator), O'Connell, N. (Contributor), Stewart, L. (Contributor), Helyar, S. (Contributor) & Garland, M. (Contributor), Queen's University Belfast, 25 May 2023
DOI: 10.17034/50fdf8c9-788e-40b0-92a1-3e38effa98ab
Dataset
File
Prizes
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Clinical an Experimental Immunology Front page cover
Stewart, L. (Recipient), Aug 2018
Prize: Other distinction
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L'Oreal UK and Ireland Fellowships for Women in Science
Stewart, L. (Recipient), 28 Jun 2012
Prize: National/international honour
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QUB Team Teaching Award
Stewart, L. (Recipient), 28 Jun 2018
Prize: Prize (including medals and awards)
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Activities
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Epitope Mapping of Human Ubiquitin and a structural homologue from Bacteroides fragilis
Stewart, L. (Advisor), English, J. (Presenter), Patrick, S. (Advisor) & Blakely, G. (Advisor)
15 Jul 2021Activity: Talk or presentation types › Oral presentation
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Epitope Mapping of Human Ubiquitin and a structural homologue from Bacteroides fragilis
Stewart, L. (Contributor), English, J. (Presenter), Patrick, S. (Contributor), Blakely, G. (Contributor) & Connolly, L. (Contributor)
15 Jul 2021Activity: Talk or presentation types › Oral presentation
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Epitope Mapping of Human Ubiquitin and a Structural Homologue from Bacteroides fragilis.
English, J. (Presenter) & Stewart, L. (Advisor)
15 Jul 2021Activity: Talk or presentation types › Oral presentation
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Epitope Mapping of Human Ubiquitin and a Structural Homologue from Bacteroides fragilis.
English, J. (Presenter) & Stewart, L. (Advisor)
26 Apr 2021Activity: Talk or presentation types › Oral presentation
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Development of a Rapid and Simple Test to Differentiate Mycobacterium bovis from Other Mycobacterium tuberculosis complex Species: Successes and Challenges
Stewart, L. (Invited speaker)
08 Sept 2020Activity: Talk or presentation types › Invited talk
Press/Media
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Researchers Discover New Link Between Autoimmune Diseases and a Gut Bacterium
29/10/2018 → 01/11/2018
4 items of Media coverage, 1 Media contribution
Press/Media: Research
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Ground Breaking Link between Autoimmune Disease and Gut Bacterium
29/10/2018
1 item of Media coverage
Press/Media: Research