• Room 01.053 - Biological Sciences

    United Kingdom

1991 …2019

Research output per year

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Personal profile

Research Focus

Linda obtained both her BSc (Joint Honours) in Genetics and Microbiology (1987) and her PhD in Clinical Microbiology (1993) at Queen's University Belfast. Her PhD was based on the gut bacterium Bacteroides fragilis and investigations of its antigenic variation in clinical samples. She completed her PhD on a part time basis while employed full time as a Senior Biomedical Scientist in the Microbiology department at Craigavon Area Hospital Group Trust before returning to research at Queen’s in 2005. As a post-doctoral researcher she worked on a number of projects producing novel binders and using these to develop new technologies for the detection of harmful contaminants in food. In 2012 she was appointed as a part-time lecturer in Microbiology which was converted to a full time position in 2015. Her research at QUB focuses on: biomarker discovery; binder generation, characterisation and mapping, including monoclonal and polyclonal antibodies, phage display derived binders, scFv antibodies; epitope mapping; and immunodiagnostic assay development and validation using a range of platforms from the research laboratory to the commercial market. She has maintained her interest in the human microbiome and is involved in research into bacterial pathogenesis and antimicrobial resistance. Key achievements include production of an anti-toxin antibody currently used in a commercially available diagnostic assay, and development of a unique novel immunodiagnostic assay capable of differentiating Mycobacterium bovis from Mycobacterium tuberculosis. She is also currently mapping epitopes on a recently identified ubiquitin like protein isolated from Bacteroides fragilis.

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Projects

Research Output

  • Open Access
    File
  • 4 Citations (Scopus)
    129 Downloads (Pure)

    Diagnostic potential of the PMS-phage assay and PMS-culture to detect Mycobacterium avium subsp. paratuberculosis in bovine milk samples

    O'Brien, L. M., McAloon, C. G., Stewart, L. D., Strain, S. A. J. & Grant, I. R., 01 May 2018, In : Transboundary and Emerging Diseases. 65, 3, p. 719-726 8 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 1 Citation (Scopus)
    80 Downloads (Pure)

    Prizes

    Best Poster

    Linda Stewart (Recipient), 25 Mar 2014

    Prize: Prize (including medals and awards)

    Clinical an Experimental Immunology Front page cover

    Linda Stewart (Recipient), Aug 2018

    Prize: Other distinction

  • L'Oreal UK and Ireland Fellowships for Women in Science

    Linda Stewart (Recipient), 28 Jun 2012

    Prize: National/international honour

  • QUB Team Teaching Award

    Linda Stewart (Recipient), 28 Jun 2018

    Prize: Prize (including medals and awards)

    Top Downloaded Article 2018

    Linda Stewart (Recipient), 06 Jun 2019

    Prize: National/international honour

  • Activities

    Epitope Mapping of Human Ubiquitin and a structural homologue from Bacteroides fragilis

    Jamie English (Speaker), Lisa Connolly (Presenter), Garry Blakely (Presenter), Sheila Patrick (Presenter), Linda Stewart (Presenter)
    Mar 2020

    Activity: Talk or presentation typesOral presentation

    Journal of Immunoassay and Immunchemistry (Journal)

    Linda Stewart (Peer reviewer)
    2019 → …

    Activity: Publication peer-review and editorial work typesPublication peer-review

    Causeway Sensors

    Linda Stewart (Advisor), Irene R. Grant (Advisor)
    Jan 2019

    Activity: Consultancy typesKTP & Consultancy in kind

    Zoonotic Tuberculosis: A neglected food safety issue

    Linda Stewart (Invited speaker), Irene R. Grant (Presenter)
    Apr 2019

    Activity: Talk or presentation typesInvited talk

    Internal Examiner

    Linda Stewart (Examiner)
    21 Jan 2019

    Activity: Examination typesOther examination

    Press / Media

    Researchers Discover New Link Between Autoimmune Diseases and a Gut Bacterium

    Linda Stewart

    29/10/201801/11/2018

    4 items of Media coverage, 1 Media contribution

    Press/Media: Research

    Ground Breaking Link between Autoimmune Disease and Gut Bacterium

    Linda Stewart

    29/10/2018

    1 item of Media coverage

    Press/Media: Research