Projects per year
Personal profile
Research Focus
Linda obtained both her BSc (Joint Honours) in Genetics and Microbiology (1987) and her PhD in Clinical Microbiology (1993) at Queen's University Belfast. Her PhD was based on the gut bacterium Bacteroides fragilis and investigations of its antigenic variation in clinical samples. She completed her PhD on a part time basis while employed full time as a Senior Biomedical Scientist in the Microbiology department at Craigavon Area Hospital Group Trust before returning to research at Queen’s in 2005. As a post-doctoral researcher she worked on a number of projects producing novel binders and using these to develop new technologies for the detection of harmful contaminants in food. In 2012 she was appointed as a part-time lecturer in Microbiology which was converted to a full time position in 2015. Her research at QUB focuses on: biomarker discovery; binder generation, characterisation and mapping, including monoclonal and polyclonal antibodies, phage display derived binders, scFv antibodies; epitope mapping; and immunodiagnostic assay development and validation using a range of platforms from the research laboratory to the commercial market. She has maintained her interest in the human microbiome and is involved in research into bacterial pathogenesis and antimicrobial resistance. Key achievements include production of an anti-toxin antibody currently used in a commercially available diagnostic assay, and development of a unique novel immunodiagnostic assay capable of differentiating Mycobacterium bovis from Mycobacterium tuberculosis. She is also currently mapping epitopes on a recently identified ubiquitin like protein isolated from Bacteroides fragilis.
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Projects
- 1 Finished
R1825GFS: Serological detection of Tuberculosis infection using novel phage display-derived peptides
16/10/2017 → 30/06/2019
Project: Research
Research Output
Biogenic Gold nanoparticles (Au NPs) as active peroxidase mimicking nanozymes for biosensing applications
Stewart, L., Cao, C., Gilbride, B., Das, B., Lou Franco, J. & Ellis, M., Oct 2019.Research output: Contribution to conference › Poster
Development of a Novel Immunoassay for differentiation of Mycobacterium bovis and Mycobacterium tuberculosis
Stewart, L., Cao, C. & Gilbride, B., Oct 2019.Research output: Contribution to conference › Poster
Retrieving Peroxidase-like Activity of Ligand-capped Gold Nanostars for the Detection of Mycobacterium bovis
Stewart, L., Cao, C., Lou Franco, J., Gilbride, B., Zhao, YJ., Elliott, C., Marco, M. -P., Ellis, M. & Salvador, J. -P., Oct 2019.Research output: Contribution to conference › Poster
Antigenic mimicry of ubiquitin by the gut bacterium Bacteroides fragilis: a potential link with autoimmune disease
Stewart, L., Edgar, D., Blakely, G. & Patrick, S., 04 Aug 2018, In : Clinical and experimental immunology.Research output: Contribution to journal › Article
Open Access
File
4
Citations
(Scopus)
129
Downloads
(Pure)
Diagnostic potential of the PMS-phage assay and PMS-culture to detect Mycobacterium avium subsp. paratuberculosis in bovine milk samples
O'Brien, L. M., McAloon, C. G., Stewart, L. D., Strain, S. A. J. & Grant, I. R., 01 May 2018, In : Transboundary and Emerging Diseases. 65, 3, p. 719-726 8 p.Research output: Contribution to journal › Article
Open Access
File
1
Citation
(Scopus)
80
Downloads
(Pure)
Prizes
Clinical an Experimental Immunology Front page cover
Linda Stewart (Recipient), Aug 2018
Prize: Other distinction
L'Oreal UK and Ireland Fellowships for Women in Science
Linda Stewart (Recipient), 28 Jun 2012
Prize: National/international honour
QUB Team Teaching Award
Linda Stewart (Recipient), 28 Jun 2018
Prize: Prize (including medals and awards)
Top Downloaded Article 2018
Linda Stewart (Recipient), 06 Jun 2019
Prize: National/international honour
Activities
Epitope Mapping of Human Ubiquitin and a structural homologue from Bacteroides fragilis
Jamie English (Speaker), Lisa Connolly (Presenter), Garry Blakely (Presenter), Sheila Patrick (Presenter), Linda Stewart (Presenter)Mar 2020
Activity: Talk or presentation types › Oral presentation
Journal of Immunoassay and Immunchemistry (Journal)
Linda Stewart (Peer reviewer)2019 → …
Activity: Publication peer-review and editorial work types › Publication peer-review
Causeway Sensors
Linda Stewart (Advisor), Irene R. Grant (Advisor)Jan 2019
Activity: Consultancy types › KTP & Consultancy in kind
Zoonotic Tuberculosis: A neglected food safety issue
Linda Stewart (Invited speaker), Irene R. Grant (Presenter)Apr 2019
Activity: Talk or presentation types › Invited talk
Press / Media
Researchers Discover New Link Between Autoimmune Diseases and a Gut Bacterium
29/10/2018 → 01/11/2018
4 items of Media coverage, 1 Media contribution
Press/Media: Research
Ground Breaking Link between Autoimmune Disease and Gut Bacterium
29/10/2018
1 item of Media coverage
Press/Media: Research