Lorcan McGarvey

2025

Role of voltage-gated Ca

Ghosh, S., Alkawadri, T., McGarvey, L. P., Hollywood, M. A., Thornbury, K. D. & Sergeant, G. P., 08 Jan 2025, (Early online date) In: American Journal of Physiology - Lung Cellular and Molecular Physiology.

Research output: Contribution to journal › Article › peer-review

2024

Brainstem processing of cough sensory inputs in chronic cough hypersensitivity

Moe, A. A. K., Singh, N., Dimmock, M., Cox, K., McGarvey, L., Chung, K. F., McGovern, A. E., McMahon, M., Richards, A. L., Farrell, M. J. & Mazzone, S. B., Feb 2024, In: EBioMedicine. 100, 15 p., 104976.

Research output: Contribution to journal › Article › peer-review

Open Access

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13 Citations (Scopus)

45 Downloads (Pure)

Cohort profile: post-hospitalisation COVID-19 (PHOSP-COVID) study

Elneima, O., McAuley, H. J. C., Leavy, O. C., Chalmers, J. D., Horsley, A., Ho, L.-P., Marks, M., Poinasamy, K., Raman, B., Shikotra, A., Singapuri, A., Sereno, M., Heaney, L. G., McGarvey, L., Baillie, J. K., Siddiqui, S., Beggs, M., Wilkinson, D., Armour, C. & McAuley, D. F. & 10 others, Peto, T., Scott, J. T., Brown, V., Drain, S., Robinson, L., Bell, D., Beggs, M., Wilson, I., Sharma, M. & PHOSP-COVID Study Collaborative Group, Feb 2024, In: International Journal of Epidemiology. 53, 1, 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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5 Citations (Scopus)

31 Downloads (Pure)

Easing the stress of chronic cough

Dąbrowska, M. & McGarvey, L., 30 Aug 2024, (Early online date) In: The Lancet. Respiratory medicine.

Research output: Contribution to journal › Comment/debate › peer-review

Inhaled corticosteroids for chronic cough: yes or FeNO?

McGarvey, L., 11 May 2024, (Early online date) In: Lung.

Research output: Contribution to journal › Editorial › peer-review

1 Citation (Scopus)

Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease

Liew, F., Anderson, D., Armour, C., Armstrong, N., Barker, R. E., Beggs, M., Begum, M., Bell, R., Brown, V., Brown, M., Brown, J., Brown, M., Brown, J., Burns, G., Burns, A., Busby, J., Byrne, S., Cairns, P., Carson, G. & Casey, A. & 76 others, Chen, J., Connolly, B., Cooper, B., Craig, T., Davies, M., Dobson, S. L., Drain, S., Elliott, K., Evans, D., Evans, R., Fallon, K., Fletcher, S., Fu, X., George, J., Grieve, D., Hanley, N., Heaney, L., Johnson, C., Jones, S., Jones, H., Jones, L., Jones, M., Kelly, S., Li, X., Marshall, M., Marshall, B., Martinez, L. M., McCormick, W., McCourt, P., McGarvey, L., McInnes, I. B., McMahon, M., McNeill, J., Miller, C. A., Mills, C., Milner, L., Mohammed, S., Nolan, C. M., Owen, J., Pavlides, M., Peto, T., Price, L., Price, D., Price, L., Richardson, M., Robinson, E., Rowland, M. J., Russell, E., Scott, J. T., Scott, K., Sharma, M., Siddiqui, S., Smith, D., Smith, S., Thomas, S., Walker, S., Walsh, S., Walsh, J. A., Ward, T. J. C., Watson, L., Wright, C., Wright, S., Young, A., Bakshi, S., Carson, G., Davis, C., Jones, C. B., Lyttle, M., Morgan, P., Murphy, M., Scott, J. T., Shaw, C. A., Smith, R., Takats, Z., PHOSP-COVID Study Collaborative Group & ISARIC investigators, Apr 2024, In: Nature Immunology. 25, 4, p. 607-621 15 p.

Research output: Contribution to journal › Letter › peer-review

Open Access

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28 Citations (Scopus)

9 Downloads (Pure)

Modulation of fast sodium current in airway smooth muscle cells by Exchange Protein Directly Activated by cAMP (Epac)

Matthews, R. M., Bradley, E., Hollywood, M. A., Lundy, F. T., McGarvey, L. P., Sergeant, G. P. & Thornbury, K. D., 01 Jan 2024, In: American Journal of Physiology - Cell Physiology. 326, p. C1-C9 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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23 Downloads (Pure)

Neutrophil-derived peptidyl arginine deiminase activity contributes to pulmonary emphysema by enhancing elastin degradation

Murphy, M. P., Hunt, D., Herron, M., McDonnell, J., Alshuhoumi, R., McGarvey, L. P., Fabre, A., O'Brien, H., McCarthy, C., Martin, S. L., McElvaney, N. G. & Reeves, E. P., 17 May 2024, (Early online date) In: Journal of Immunology. 213, 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Citations (Scopus)

Structural predictors of lung function decline in the British early COPD network (BEACON) cohort

Ritchie, A. I., Hoffman, E. A., Allinson, J. P., Bloom, C. I., Bolton, C. E. R., Choudhury, G., Gerard, S. E., Guo, J., Alves-Moreira, L., Mcgarvey, L., Sapey, E., Stockley, R. A., Vestbo, J., Singh, D., Yip, K. P., Wilkinson, T., Mullerova, H., Ostridge, K., Mezzi, K. & Jöns, O. & 5 others, Bucchioni, E., Calverley, P. M., Compton, C., Jones, P. W. & Wedzicha, J. A., 22 May 2024, In: American Journal of Respiratory and Critical Care Medicine. 209, 2 p., A6653.

Research output: Contribution to journal › Meeting abstract › peer-review

Structural predictors of lung function decline in young smokers with normal spirometry

Ritchie, A. I., Donaldson, G. C., Hoffman, E. A., Allinson, J. P., Bloom, C. I., Bolton, C. E., Choudhury, G., Gerard, S. E., Guo, J., Alves-Moreira, L., McGarvey, L., Sapey, E., Stockley, R. A., Yip, K. P., Singh, D., Wilkinson, T., Fageras, M., Ostridge, K., Jöns, O. & Bucchioni, E. & 6 others, Compton, C. H., Jones, P., Mezzi, K., Vestbo, J., Calverley, P. M. A. & Wedzicha, J. A., 15 May 2024, In: American Journal of Respiratory and Critical Care Medicine. 209, 10, p. 1208-1218

Research output: Contribution to journal › Article › peer-review

Open Access

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17 Citations (Scopus)

104 Downloads (Pure)

The clinical approach to chronic cough

Satia, I., Hassan, W., McGarvey, L. & Birring, S. S., 16 Nov 2024, (Early online date) In: Journal of Allergy and Clinical Immunology: In Practice.

Research output: Contribution to journal › Article › peer-review

Open Access

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6 Downloads (Pure)

TRPV2 modulates mechanically induced ATP release from human bronchial epithelial cells

Dunne, O. M., Martin, S. L., Sergeant, G. P., McAuley, D. F., O’Kane, C. M., Button, B., McGarvey, L. P. & Lundy, F. T., 27 Apr 2024, In: Respiratory Research. 25, 10 p., 188.

Research output: Contribution to journal › Article › peer-review

Open Access

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1 Citation (Scopus)

15 Downloads (Pure)

2023

Adverse perception of cough in patients with severe asthma: a discrete choice experiment

Holmes, J., O'Neill, V., McGarvey, L. P. & Heaney, L. G., 01 Jan 2023, In: ERJ Open Research. 9, 1, 10 p., 00442-2022.

Research output: Contribution to journal › Article › peer-review

Open Access

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8 Citations (Scopus)

58 Downloads (Pure)

A real world study of cough burden and quality of life of UK patients who have undergone evaluation for chronic cough

McGarvey, L. P., Harper, G., Silvey, M. & Langerman, H., 23 Nov 2023, (Early online date) In: Current medical research and opinion. 12 p.

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

British Thoracic Society clinical statement on chronic cough in adults

Parker, S. M., Smith, J. A., Birring, S. S., Chamberlain-Mitchell, S., Gruffydd-Jones, K., Haines, J., Hennessey, S., McGarvey, L. P., Marsden, P., Martin, M. J., Morice, A., O'Hara, J. & Thomas, M., 06 Dec 2023, In: Thorax. 78, Suppl 6, p. s3-s19

Research output: Contribution to journal › Article › peer-review

Open Access

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33 Citations (Scopus)

404 Downloads (Pure)

Burden of chronic cough in the UK: results from the 2018 National Health and Wellness Survey

McGarvey, L., Morice, A. H., Martin, A., Li, V. W., Doane, M. J., Urdaneta, E., Schelfhout, J., Ding, H. & Fonseca, E., 17 Jul 2023, In: ERJ Open Research. 9, 4, 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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15 Citations (Scopus)

28 Downloads (Pure)

Consensus goals and standards for specialist cough clinics: the NEUROCOUGH international Delphi study

Song, W.-J., Dupont, L., Birring, S. S., Chung, K. F., Dąbrowska, M., Dicpinigaitis, P., Ribas, C. D., Fontana, G., Gibson, P. G., Guilleminault, L., Hull, J. H., Idzko, M., Kardos, P., Kim, H. J., Lai, K., Lavorini, F., Millqvist, E., Morice, A. H., Niimi, A. & Parker, S. M. & 4 others, Satia, I., Smith, J. A., van den Berg, J. W. & McGarvey, L. P., 20 Nov 2023, In: ERJ Open Research. 9, 6, 13 p., 00618.

Research output: Contribution to journal › Article › peer-review

Open Access

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10 Citations (Scopus)

25 Downloads (Pure)

Demographic, clinical, and patient-reported outcome data from 2 global, phase 3 trials of chronic cough

Dicpinigaitis, P. V., Birring, S. S., Blaiss, M., McGarvey, L. P., Morice, A. H., Pavord, I. D., Satia, I., Smith, J. A., La Rosa, C., Li, Q., Nguyen, A. M., Schelfhout, J., Tzontcheva, A. & Muccino, D., 02 Jan 2023, In: Annals of Allergy, Asthma and Immunology. 130, 1, p. 60-66

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Efficacy and safety of eliapixant in refractory chronic cough: the randomized, placebo-controlled phase 2b PAGANINI study

Dicpinigaitis, P. V., Morice, A. H., Smith, J. A., Sher, M. R., Vaezi, M., Guilleminault, L., Niimi, A., Gude, K., Krahn, U., Saarinen, R., Pires, P. V., Wosnitza, M. & McGarvey, L., 01 Jun 2023, In: Lung. 12 p.

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Efficacy and safety of gefapixant for refractory or unexplained chronic cough over 52 weeks

Birring, S. S., Dicpinigaitis, P. V., Smith, J. A., Morice, A. H., McGarvey, L. P., Pavord, I. D., Martin Nguyen, A., Schelfhout, J., Li, Q., Iskold, B., Green, S. A., Philip, G., Muccino, D. R. & La Rosa, C., 30 Mar 2023, (Early online date) In: American Journal of Respiratory and Critical Care Medicine.

Research output: Contribution to journal › Article › peer-review

Open Access

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10 Citations (Scopus)

19 Downloads (Pure)

From bench to bedside: The role of cough hypersensitivity in chronic cough

Drake, M. G., McGarvey, L. P. & Morice, A. H., Aug 2023, In: Clinical and Translational Medicine. 13, 8, e1343.

Research output: Contribution to journal › Review article › peer-review

Open Access

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60 Downloads (Pure)

Higher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial

Abdullah, A., Ahmad, M., Alderdice, D., Alexander, J., Alexander, P. D. G., Ali, S., Allen, K., Anderson, J., Anderson, S., Anderson, W., Baker, M., Barlow, R., Brady, C., Brown, A., Browne, D., Burns, A., Campbell, M., Carr, S., Chambers, E. & Chapman, K. & 151 others, Clark, P., Collins, E., Comer, D., Cooper, D., Craig, V., Cunningham, N., Curran, D., Davies, B., Davies, S., Dawson, E., Doherty, C., Donnelly, E., Donnelly, R., Downey, D., Drain, M., Evans, E., Evans, J., Evans, J., Ferguson, J., Fowler, S., Gallagher, W., Gordon, C., Gosling, R., Grant, D., Green, D., Griffiths, S., Hameed, M., Harrison, T., Hart, D., Heron, E., Hewitt, R., Hughes, S., Ibrahim, A., Jackson, A., Johnson, G., Johnson, M., Johnston, J., Jones, A., Jones, L., Jones, S., Jones, S., Jones, T., Keegan, B., Kelly, D., Kelly, D., Kelly, E., Kelly, M., Kelly, M., Kelly, S., Kerr, A., Khan, W., Kinnear, D. J., Kumar, S., Lee, S., Linden, D., Malone, E., Marshall, A., McCourt, P., McDermott, J., McElwaine, F., McGarvey, L., McGettigan, C., McGrath, B., McMahon, S., McManus, T., McMaster, P., McNally, H., Millar, J., Molloy, A., Moore, D. A. J., Moore, L., Morgan, P., Morris, P., Murray, C., Murray, L., Murray, T., Nguyen, Q., Nguyen, T. T. P., North, F., Nugent, A. M., O'Gorman, C., Orr, S., Patterson, R., Quinn, J., Regan, M., Rehman, A., Reid, A., Reid, J., Rice, M., Ritchie, J., Robinson, E., Robinson, M., Rogers, J., Rowan, S., Ryan, K., Saad, M., Scott, A., Scott, S., Shah, S., Shaw, C., Simms, R., Simpson, T., Simpson, K., Sloan, B., Smith, C., Smith, C., Smith, O., Smith, R., Smith, R., Smith, S., Smith, S., Smith, S., Smith, J., Sreenivasan, S., Stevenson, A., Stewart, C., Tan, W. T., Taylor, J., Taylor, S., Taylor, V., Thompson, C., Thompson, L., Thompson, L., Tinkler, M., Walsh, E., Walters, J., Walton, M., Wang, R., Ward, C., Ward, H., Ward, N., Ward, T., Watson, J. G. R., Watson, R., Webster, D., Webster, I., White, C., White, J., Williams, G., Williams, J., Williams, J., Williams, M., Williams, R., Williamson, J. D., Wilson, A., Wilson, A., Wilson, D., Wilson, M., Zhang, J., Zhao, X. & RECOVERY Collaborative Group, 06 May 2023, In: The Lancet. 401, 10387, p. 1499-1507 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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67 Citations (Scopus)

35 Downloads (Pure)

Long COVID research: an update from the PHOSP-COVID Scientific Summit

Evans, R. A., Bingham, M., Jenkins, R. G., McCann, G. P., Mitchell, J., Semple, M. G., Smith, N., Walker, S., Ahmad, S., Ali, M., Anderson, D., Armour, C., Armstrong, N., Baillie, J. K., Banerjee, A., Barker, R. E., Begum, M., Bell, M., Bell, R. & Bennett, K. & 192 others, Bourne, M., Brown, V., Brown, M., Brown, J. S., Brown, A., Brown, J. S., Burns, G., Burns, A., Busby, J., Butt, A., Byrne, S., Cairns, P., Carr, C., Carson, G., Casey, A., Chambers, R. C., Chapman, K., Chen, J., Cheng, Y., Clarke, J., Cole, J., Connolly, B., Cooper, S., Cooper, B., Cooper, J., Craig, T., Cross, A., Daly, P., Davies, G., Davies, G., Davies, M. J., Dawson, C., Dobson, S. L., Drain, S., Edwards, S., Elliott, A., Elliott, K., Evans, R. A., Evans, D., Evans, R. A., Evans, J., Fletcher, S., Flynn, M., Ford, A., Francis, S., Fu, X., Geddes, J. R., George, J., Glover, S., Goodwin, C., Greenwood, J., Grieve, D., Griffin, D., Gupta, A., Hall, L., Hanley, N. A., Harrington, K., Harris, E., Hart, N., Harvey, A., Harvey, M., Heaney, L. G., Hewitt, M., Holloway, L., Howard, K., Hughes, R. A., Hughes, J., Hughes, A. D., Hutchinson, J., Johnson, C., Johnson, S., Johnston, D., Jones, S., Jones, H., Jones, L., Jones, M. G., Jones, D., Kelly, S., Kerr, S., Khan, F., Kilroy, S., King, B., Kirk, J., Lee, J. H., Lewis, J., Li, X., Lynch, C., Magee, N., Marshall, M., Marshall, B., Martin, J., Martinez, L. M., Matthews, L., McArdle, A., McCormick, W., McCormick, J., McCourt, P., McCracken, C., McGarvey, L., McInnes, I. B., McIntosh, J., McIvor, K., McMahon, A., McMahon, M. J., Mcnally, T., McNeill, J., Miller, C. A., Mills, C., Mills, G., Milner, L., Mohamed, A., Mohammed, S., Morrison, L., Neill, P., Newman, T., Nolan, C. M., O'Brien, C., O'Donnell, K., O'Brien, L., Owen, J., Palmer, S., Pavlides, M., Peng, Y., Peto, T., Porter, J. C., Porter, J. C., Powell, N., Pratt, J., Price, A., Price, C., Price, L., Price, D., Richardson, M., Rahman, N. M., Reed, A., Robertson, E., Robinson, L., Robinson, E., Ross, G., Ross, A., Rowland, M. J., Roy, M., Russell, E., Scott, J. T., Scott, K., Sewell, T. A., Shah, A., Sharma, M., Shaw, A., Shaw, K., Siddiqui, S., Simpson, N., Simpson, J., Singh, S., Singh, S., Smith, D., Smith, A., Smith, J., Smith, L., Smith, S., Stewart, I., Taylor, J. P., Taylor, A., Taylor, C., Taylor, J. P., Thomas, S., Thomas, C., Thompson, A. A. R., Thompson, T., Tomlinson, J., Turner, S., Walmsley, S., Walsh, S., Walsh, J. A., Ward, T. J. C., Watson, L., Watson, E., Watson, J., White, S., Wilkinson, D., Williams, J., Wilson, A., Wilson, I., Wilson, D., Woods, J., Wright, C., Wright, S., Wright, L., Xu, M., Young, S., Young, A. & PHOSP-COVID Study Collaborative Group, 01 Nov 2023, In: The Lancet Respiratory Medicine. 11, 11, p. e93-e94 2 p.

Research output: Contribution to journal › Letter › peer-review

5 Citations (Scopus)

Multiorgan MRI findings after hospitalisation with COVID-19 in the UK (C-MORE): a prospective, multicentre, observational cohort study

Brown, J., Jones, M. G., Davies, M. J., Rowland, M. J., Scott, J. T., Heaney, L. G., Hughes, P. J. C., Smith, S., Baillie, J. K., Walker, S., Armour, C., McGarvey, L., Magee, N., Drain, S., Craig, T., Watson, L., Robertson, E., McCormick, W., Martinez, L. M. & Owen, J. & 88 others, Mills, C., Wright, C., Russell, E., Johnston, D., Mitchell, J., Price, L., Walsh, S., McMahon, A., Byrne, S., Dobson, S. L., McIvor, K., Hanley, N. A., Young, A., Price, D., Burns, G., Simpson, J., Wright, S., McMahon, M. J., Anderson, D., Grieve, D., McInnes, I. B., George, J., Mohammed, S., Chen, J., Pavlides, M., Burns, A., Connolly, B., Busby, J., Peto, T., Nolan, C. M., Walsh, J. A., Barker, R. E., Johnson, C., Milner, L., Begum, M., Marshall, M., McNeill, J., Banerjee, A., Xu, M., Bell, R., Chambers, R. C., Casey, A., Cooper, B., Wilson, D., Marshall, B., Harvey, M., Fletcher, S., Mills, G., Armstrong, N., Cairns, P., McCourt, P., Siddiqui, S., Ward, T. J. C., Mcnally, T., Wilkinson, D., Walmsley, S., O'Donnell, K., Sharma, M., McArdle, A., Khan, F., Stewart, I., Wright, L., Johnson, S., Fu, X., Li, X., Carson, G., Robinson, E., Cooper, J., Elliott, K., Brown, V., Brown, M., Brown, J., Jones, S., Jones, H., Jones, L., Howard, K., Scott, K., Thomas, S., Lewis, J., Hughes, A. D., Thompson, T., Kelly, S., Smith, D., Smith, S., Evans, D., Evans, R., Evans, J. & The C-MORE/PHOSP-COVID Collaborative Group, 01 Nov 2023, In: The Lancet Respiratory Medicine. 11, 11, p. 1003-1019 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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29 Citations (Scopus)

21 Downloads (Pure)

Prevalence of physical frailty, including risk factors, up to 1 year after hospitalisation for COVID-19 in the UK: a multicentre, longitudinal cohort study

McAuley, H. J. C., Evans, R. A., Bolton, C. E., Brightling, C. E., Chalmers, J. D., Docherty, A. B., Elneima, O., Greenhaff, P. L., Gupta, A., Harris, V. C., Harrison, E. M., Ho, L.-P., Horsley, A., Houchen-Wolloff, L., Jolley, C. J., Leavy, O. C., Lone, N. I., Man, W.D.-C., Marks, M. & Parekh, D. & 37 others, Poinasamy, K., Quint, J. K., Raman, B., Richardson, M., Saunders, R. M., Sereno, M., Shikotra, A., Singapuri, A., Singh, S. J., Steiner, M., Tan, A. L., Wain, L. V., Welch, C., Whitney, J., Witham, M. D., Lord, J., Greening, N. J., PHOSP-COVID Study Collaborative Group, Armour, C., Busby, J., Connolly, B., Drain, S., Grieve, D., Hart, N., Harvey, M., Heaney, L. G., Hughes, J., Jones, M. G., Magee, N., McArdle, A., McGarvey, L., Mills, C., Mitchell, J., Peto, T., Rowland, M., Sharma, M. & Siddiqui, S., 11 Mar 2023, In: eClinicalMedicine. 57, 101896.

Research output: Contribution to journal › Article › peer-review

Open Access

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14 Citations (Scopus)

63 Downloads (Pure)

Reply to Weinberger

Birring, S. S., Morice, A. H., Dicpinigaitis, P. V., McGarvey, L. P., Pavord, I. D., Green, S. A., Philip, G. & Smith, J. A., 15 Jun 2023, In: American Journal of Respiratory and Critical Care Medicine. 207, 12, p. 1650-1651

Research output: Contribution to journal › Letter

Open Access

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1 Citation (Scopus)

87 Downloads (Pure)

SARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination

Liew, F., Talwar, S., Cross, A., Willett, B. J., Scott, S., Logan, N., Siggins, M. K., Swieboda, D., Sidhu, J. K., Efstathiou, C., Moore, S. C., Davis, C., Mohamed, N., Nunag, J., King, C., Thompson, A. A. R., Rowland-Jones, S. L., Docherty, A. B., Chalmers, J. D. & Ho, L.-P. & 44 others, Horsley, A., Raman, B., Poinasamy, K., Marks, M., Kon, O. M., Howard, L., Wootton, D. G., Dunachie, S., Quint, J. K., Evans, R. A., Wain, L. V., Fontanella, S., de Silva, T. I., Ho, A., Harrison, E., Baillie, J. K., Semple, M. G., Brightling, C., Thwaites, R. S., Turtle, L., Openshaw, P. J. M., ISARIC4C Investigators, Armour, C., Carson, G., Busby, J., Connolly, B., Cooper, J., Drain, S., Grieve, D., Hart, N., Harvey, M., Heaney, L. G., Hughes, J., Jones, M. G., Magee, N., McArdle, A., McGarvey, L., Mills, C., Mitchell, J., Peto, T., Powell, N., Rowland, M., Sharma, M. & Siddiqui, S., 16 Jan 2023, In: EBioMedicine. 87, 104402.

Research output: Contribution to journal › Article › peer-review

Open Access

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73 Citations (Scopus)

32 Downloads (Pure)

Speaking the language of cough for our patients

McGarvey, L., Morice, A. & Dupont, L., Nov 2023, In: Respiratory Medicine and Research. 84, 2 p., 101036.

Research output: Contribution to journal › Editorial › peer-review

The efficacy and safety of gefapixant in a phase 3b trial of patients with recent-onset chronic cough

McGarvey, L., Sher, M., Shvarts, Y. G., Lu, S., Wu, W.-C., Xu, P., Schelfhout, J., La Rosa, C., Nguyen, A. M., Reyfman, P. A. & Afzal, A. S., 06 Mar 2023, (Early online date) In: Lung. 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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19 Citations (Scopus)

64 Downloads (Pure)

The P2X3 receptor antagonist filapixant in patients with refractory chronic cough: a randomized controlled trial

Friedrich, C., Francke, K., Birring, S. S., van den Berg, J. W. K., Marsden, P. A., McGarvey, L., Turner, A. M., Wielders, P., Gashaw, I., Klein, S. & Morice, A. H., 11 Apr 2023, (Early online date) In: Respiratory Research. 24, 109.

Research output: Contribution to journal › Article › peer-review

Open Access

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16 Citations (Scopus)

32 Downloads (Pure)

2022

Airway remodelling rather than cellular infiltration characterizes both type2 cytokine biomarker‐high and ‐low severe asthma

Khalfaoui, L., Symon, F. A., Couillard, S., Hargadon, B., Chaudhuri, R., Bicknell, S., Mansur, A. H., Shrimanker, R., Hinks, T. C., Pavord, I. D., Fowler, S. J., Brown, V., McGarvey, L. P., Heaney, L. G., Austin, C. D., Howarth, P. H., Arron, J. R., Choy, D. F. & Bradding, P., 25 May 2022, (Early online date) In: Allergy.

Research output: Contribution to journal › Article › peer-review

Open Access

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19 Citations (Scopus)

362 Downloads (Pure)

An observational study to determine the relationship between cough frequency and markers of inflammation in severe asthma

Holmes, J., McGarvey, L. P., Birring, S. S., Fletcher, H. & Heaney, L. G., 01 Dec 2022, In: European Respiratory Journal. 60, 6, 9 p., 2103205.

Research output: Contribution to journal › Article › peer-review

Open Access

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7 Citations (Scopus)

41 Downloads (Pure)

A randomized, double-blind, placebo-controlled, parallel-group phase 2b trial of p2x3 receptor antagonist sivopixant for refractory or unexplained chronic cough

McGarvey, L., Smith, J. A., Morice, A., Birring, S. S., Chung, K. F., Dicpinigaitis, P. V., Niimi, A., Benninger, M. S., Sher, M., Matsunaga, Y., Miyazaki, S., Machida, M., Ishihara, H., Mahmood, A. & Gomez, J.-C., 13 Dec 2022, (Early online date) In: Lung. 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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24 Citations (Scopus)

55 Downloads (Pure)

Aspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Downey, D., Linden, D., McGarvey, L. & RECOVERY Collaborative Group, 08 Jan 2022, In: The Lancet. 399, 10320, p. 143-151 9 p.

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219 Citations (Scopus)

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Assessing cough symptom severity in refractory or unexplained chronic cough: findings from patient focus groups and an international expert panel

Kum, E., Guyatt, G. H., Munoz, C., Beaudin, S., Li, S.-A., Abdulqawi, R., Badri, H., Boulet, L.-P., Chen, R., Dicpinigaitis, P., Dupont, L., Field, S. K., French, C. L., Gibson, P. G., Irwin, R. S., Marsden, P., McGarvey, L., Smith, J. A., Song, W.-J. & O'Byrne, P. M. & 1 others, Satia, I., 14 Mar 2022, (Early online date) In: ERJ Open Research. 8, 1, 17 p.

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18 Citations (Scopus)

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Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis

Abdullah, A., Ahmad, M., Alderdice, D., Alexander, J., Alexander, P. D. G., Ali, S., Allen, K., Anderson, J., Anderson, S., Anderson, W., Baker, M., Barlow, R., Brady, C., Brown, A., Browne, D., Burns, A., Campbell, M., Carr, S., Chambers, E. & Chapman, K. & 147 others, Clark, P., Collins, E., Comer, D., Cooper, D., Craig, V., Cunningham, N., Curran, D., Davies, S., Dawson, E., Doherty, C., Donnelly, E., Donnelly, R., Downey, D., Drain, M., Evans, J., Evans, J., Ferguson, J., Fowler, S., Gallagher, W., Gordon, C., Gosling, R., Grant, D., Green, D., Griffiths, S., Hameed, M., Harrison, T., Hart, D., Heron, E., Hewitt, R., Hughes, S., Ibrahim, A., Jackson, A., Johnson, G., Johnson, M., Johnston, J., Jones, A., Jones, L., Jones, S., Jones, S., Jones, T., Keegan, B., Kelly, D., Kelly, D., Kelly, E., Kelly, M., Kelly, M., Kelly, S., Kerr, A., Khan, W., Kinnear, D. J., Kumar, S., Lee, S., Linden, D., Malone, E., Marshall, A., McCourt, P., McDermott, J., McElwaine, F., McGarvey, L., McGettigan, C., McGrath, B., McMahon, S., McManus, T., McNally, H., Millar, J., Molloy, A., Moore, D. A. J., Moore, L., Morgan, P., Morris, P., Murray, C., Murray, L., Murray, T., Nguyen, Q., North, F., Nugent, A. M., O'Gorman, C., Orr, S., Patterson, R., Quinn, J., Regan, M., Rehman, A., Reid, A., Reid, J., Rice, M., Ritchie, J., Robinson, E., Robinson, M., Rogers, J., Rowan, S., Ryan, K., Saad, M., Scott, A., Scott, S., Shah, S., Shaw, C., Simms, R., Simpson, T., Simpson, K., Sloan, B., Smith, C., Smith, C., Smith, O., Smith, R., Smith, R., Smith, S., Smith, S., Smith, S., Smith, J., Sreenivasan, S., Stevenson, A., Stewart, C., Tan, W. T., Taylor, J., Taylor, S., Taylor, V., Thompson, C., Thompson, L., Thompson, L., Tinkler, M., Walsh, E., Walters, J., Walton, M., Wang, R., Ward, C., Ward, H., Ward, N., Ward, T., Watson, J. G. R., Watson, R., Webster, D., Webster, I., White, C., White, J., Williams, G., Williams, J., Williams, J., Williams, M., Williams, R., Williamson, J. D., Wilson, A., Wilson, A., Wilson, D., Wilson, M., Zhang, J., Zhao, X. & RECOVERY Collaborative Group, 30 Jul 2022, In: The Lancet. 400, 10349, p. 359-368 10 p.

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194 Citations (Scopus)

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Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Downey, D., Linden, D., McGarvey, L. & RECOVERY Collaborative Group, 12 Feb 2022, In: The Lancet. 399, 10325, p. 665-676 12 p.

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254 Citations (Scopus)

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Chronic cough and cough hypersensitivity: from mechanistic insights to novel antitussives

Mazzone, S. B., Satia, I., McGarvey, L., Song, W.-J. & Chung, K. F., 01 Dec 2022, In: The Lancet. Respiratory medicine. 10, 12, p. P1113-1115

Research output: Contribution to journal › Comment/debate › peer-review

7 Citations (Scopus)

Chronic cough in asthma is associated with increased airway inflammation, more comorbidities, and worse clinical outcomes

Deng, S. J., Wang, J., Liu, L., Zhang, X., Gibson, P. G., Chen, Z. H., Birring, S. S., Xie, M., Lai, K. F., Qin, L., Liu, D., Vertigan, A. E., Song, W.-J., McGarvey, L., Luo, F. M., Chung, K. F., Li, W. M. & Wang, G., 01 May 2022, In: Allergy and asthma proceedings. 43, 3, p. 209-219

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study

Evans, R. A., Richardson, M., Brown, J. S., Hart, N., Jones, M. G., Rahman, N. M., Shah, A. M., Davies, M. J., Geddes, J. R., Heaney, L. G., Jenkins, R. G., McCann, G. P., Porter, J. C., Rowland, M. J., Scott, J. T., Semple, M. G., Singh, S. J., Kerr, S., Ahmad, S. & Ali, M. & 179 others, Armour, C., Baillie, J. K., Banerjee, A., Barker, R. E., Begum, M., Bell, D., Bell, R., Bennett, K., Bingham, M., Bourne, M., Brown, A., Brown, J. S., Brown, M., Brown, V., Burns, G., Burns, A., Busby, J., Butt, A., Byrne, S., Cairns, P., Carr, C., Carson, G., Casey, A., Chambers, R. C., Chapman, K., Chen, J., Cheng, Y., Clarke, J., Cole, J., Connolly, B., Cooper, B., Cooper, J., Cooper, S., Craig, T., Cross, A., Daly, P., Davies, G., Davies, G., Dobson, S. L., Drain, S., Edwards, S., Elliott, A., Elliott, K., Evans, D., Evans, J., Evans, R. A., Evans, R. A., Fletcher, S., Flynn, M., Ford, A., Francis, S., Fu, X., George, J., Glover, S., Goodwin, C., Greenwood, J., Grieve, D., Griffin, D., Gupta, A., Hall, L., Hanley, N. A., Harrington, K., Harris, E., Harvey, A., Harvey, M., Hewitt, M., Holloway, L., Howard, K., Hughes, A. D., Hughes, J., Hughes, R., Hutchinson, J., Johnson, C., Johnson, S., Johnston, D., Jones, D., Jones, H., Jones, L., Jones, S., Kelly, S., Khan, F., Kilroy, S., King, B., Kirk, J., Lee, J. H., Lewis, J., Li, X., Lynch, C., Magee, N., Marshall, B., Marshall, M., Martin, J., Matthews, L., McArdle, A., McCormick, J., McCormick, W., McCourt, P., McGarvey, L., McInnes, I. B., McIntosh, J., McIvor, K., McMahon, A., McMahon, M. J., Mcnally, T., McNeill, J., Miller, C., Mills, C., Milner, L., Mitchell, J., Mohamed, A., Mohammed, S., Morrison, L., Newman, T., Nolan, C. M., O'Donnell, K., O'Brien, C., O'Brien, L., Owen, J., Palmer, S., Pavlides, M., Peng, Y., Peto, T., Porter, J. C., Powell, N., Pratt, J., Price, A., Price, D., Price, L., Reed, A., Robertson, E., Robinson, E., Robinson, L., Ross, A., Ross, G., Roy, M., Russell, E., Scott, K., Sewell, T. A., Sharma, M., Shaw, A., Siddiqui, S., Simpson, J., Simpson, N., Singh, S. J., Smith, A., Smith, D., Smith, S., Smith, J., Smith, L., Stewart, I., Taylor, A., Taylor, C., Taylor, J., Thomas, C., Thomas, S., Thompson, T., Thompson, A. A. R., Turner, S., Walker, S., Walsh, J. A., Walsh, S., Ward, T. J. C., Watson, E., Watson, L., Watson, J., White, S., Wilkinson, D., Williams, J., Wilson, A., Wilson, D., Wilson, I., Woods, J., Wright, C., Wright, L., Wright, S., Xu, M., Young, S., Young, A. & PHOSP-COVID Study Collaborative Group, 01 Aug 2022, In: The Lancet Respiratory Medicine. 10, 8, p. 761-775 15 p.

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249 Citations (Scopus)

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Cough hypersensitivity and chronic cough

Chung, K. F., McGarvey, L., Song, W.-J., Chang, A. B., Lai, K., Canning, B. J., Birring, S. S., Smith, J. A. & Mazzone, S. B., 30 Jun 2022, In: Nature reviews. Disease primers. 8, 45.

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153 Citations (Scopus)

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Early-phase clinical trials in a pandemic: learning from the response to COVID-19

NIHR Respiratory Translational Research Collaboration network, Jul 2022, In: The Lancet. Respiratory medicine. 10, 7, p. 625-627

Research output: Contribution to journal › Comment/debate › peer-review

2 Citations (Scopus)

Efficacy and safety of gefapixant, a P2X₃ receptor antagonist, in refractory chronic cough and unexplained chronic cough (COUGH-1 and COUGH-2): results from two double-blind, randomised, parallel-group, placebo-controlled, phase 3 trials

COUGH-1 and COUGH-2 Investigators, 05 Mar 2022, In: The Lancet. 399, 10328, p. 909-923 15 p.

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194 Citations (Scopus)

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Functional expression of Na_V1.7 channels in freshly dispersed mouse bronchial smooth muscle cells

Matthews, R. M., Bradley, E., Griffin, C. S., Lim, X. R., Mullins, N. D., Hollywood, M. A., Lundy, F. T., McGarvey, L. P., Sergeant, G. P. & Thornbury, K. D., 01 Sept 2022, In: American journal of physiology. Cell physiology. 323, 3, p. C749-C762

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3 Citations (Scopus)

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Glucocorticoid toxicity reduction with Mepolizumab using the glucocorticoid toxicity index

McDowell, P. J., Stone, J. H., Zhang, Y., Honeyford, K., Dunn, L., Logan, R. J., McGarvey, L. P. A., Butler, C. A. & Heaney, L. G., 20 Jan 2022, In: European Respiratory Journal. 59, 1

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14 Citations (Scopus)

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Improvements in Objective and Subjective Measures of Chronic Cough with Gefapixant: A Pooled Phase 3 Efficacy Analysis of Predefined Subgroups

Smith, J. A., Birring, S. S., Dicpinigaitis, P. V., McGarvey, L. P., Morice, A. H., Pavord, I. D., Satia, I., Green, S., Iskold, B., La Rosa, C., Li, Q., Martin Nguyen, A., Schelfhout, J. & Muccino, D., 01 Aug 2022, In: Lung. 200, 4, p. 423-429 7 p.

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5 Citations (Scopus)

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Large scale clinical trials: lessons from the COVID-19 pandemic

Horsley, A. R., Pearmain, L., Knight, S., Schindler, N., Wang, R., Bennett, M., Robey, R. C., Davies, J. C., Djukanović, R., Heaney, L. G., Hussell, T., Marciniak, S. J., McGarvey, L. P., Porter, J., Wilkinson, T., Brightling, C. & Ho, L.-P., 14 Jun 2022, In: BMJ Open Respiratory Research. 9, 1, e001226.

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7 Citations (Scopus)

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M2 muscarinic receptor-dependent contractions of airway smooth muscle are inhibited by activation of β-adrenoceptors

Alkawadri, T., Wong, P. Y., Fong, Z., Lundy, F. T., McGarvey, L. P., Hollywood, M. A., Thornbury, K. D. & Sergeant, G. P., 29 Oct 2022, In: Function. 3, 6, 10 p., zqac050.

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1 Citation (Scopus)

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Objective and Subjective Measurement of Cough in Asthma; A Systematic Review of the Literature

Holmes, J., Heaney, L. G. & McGarvey, L. P. A., 13 Apr 2022, In: Lung. 200, 2, p. 169-178 10 p.

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9 Citations (Scopus)

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Potent inhibition of matriptase by serpin A5 is abrogated by heparin-binding.

Kelly-Robinson, G., Tikhonova, I., Douglas, L., Reihill, J., Lundy, F., McGarvey, L., Litherland, G., Thornbury, K. & Martin, L., 17 Sept 2022, (Unpublished).

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Lorcan McGarvey

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