• Room 03.007 - Medical Biology Centre

    United Kingdom

20032019
If you made any changes in Pure these will be visible here soon.

Research Output 2003 2019

2019

Post-streptococcal uveitis syndrome in a Caucasian population: a case series

Curragh, D. S., McAvoy, C. E., Rooney, M. & McLoone, E., 01 Mar 2019, In : Eye (Basingstoke). 33, 3, p. 380-384 5 p.

Research output: Contribution to journalArticle

Uveitis
Population
Pediatrics
Deoxyribonucleases
Case Management
1 Citation (Scopus)
43 Downloads (Pure)

The prevention and treatment of glucocorticoid-induced osteopaenia in juvenile rheumatic disease: A randomised double-blind controlled trial

British Society for Paediatric and Adolescent Rheumatology UK, 01 Jul 2019, In : EClinicalMedicine - published by THE LANCET. 12, p. 79-87 9 p.

Research output: Contribution to journalArticle

Open Access
File
Rheumatic Diseases
Glucocorticoids
Placebos
Steroids
Diphosphonates
2018
42 Downloads (Pure)

Protective parents and permissive children: What qualitative interviews with parents and children can tell us about the feasibility of juvenile idiopathic arthritis trials

Sherratt, F. C., Roper, L., Stones, S. R., McErlane, F., Peak, M., Beresford, M. W., Foster, H., Ramanan, A. V., Rooney, M., Baildam, E. & Young, B., 04 Dec 2018, In : Pediatric Rheumatology. 16, 1, 76.

Research output: Contribution to journalArticle

Open Access
File
Juvenile Arthritis
Parents
Interviews
Adrenal Cortex Hormones
Feasibility Studies
2017
Hydrogel
Methotrexate
Skin
Drug Delivery Systems
Juvenile Arthritis
3 Citations (Scopus)

Pediatric Uveitis in a Well-Defined Population: Improved Outcomes with Immunosuppressive Therapy

Curragh, D. S., O’Neill, M., McAvoy, C. E., Rooney, M. & McLoone, E., 18 Aug 2017, In : Ocular Immunology and Inflammation. 26, 6, p. 978-985

Research output: Contribution to journalArticle

Uveitis
Immunosuppressive Agents
Pediatrics
Population
Visual Acuity
2016
Open Access
Juvenile Arthritis
Hydrogel
Methotrexate
Alcohols
Therapeutics
2015
18 Citations (Scopus)

Antiviral antibody profiling by high-density protein arrays

Bian, X., Wiktor, P., Kahn, P., Brunner, A., Khela, A., Karthikeyan, K., Barker, K., Yu, X., Magee, M., Wasserfall, C. H., Gibson, D., Rooney, M. E., Qiu, J. & LaBaer, J., Jun 2015, In : Proteomics. 15, 12, p. 2136-2145 10 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
206 Downloads (Pure)
Open Access
File
Juvenile Arthritis
Methotrexate
Cross-Sectional Studies
Therapeutics
methotrexate polyglutamate
2014
9 Citations (Scopus)
318 Downloads (Pure)

A Novel Dried Blood Spot-LCMS Method for the Quantification of Methotrexate Polyglutamates as a Potential Marker for Methotrexate Use in Children

Hawwa, A. F., AlBawab, A., Rooney, M., Wedderburn, L. R., Beresford, M. W. & McElnay, J. C., Feb 2014, In : PLoS ONE. 9, 2, 11 p., e89908.

Research output: Contribution to journalArticle

Open Access
File
Dried Blood Spot Testing
methotrexate
Methotrexate
Blood
blood
15 Citations (Scopus)

A study of erosive phenotypes in lupus arthritis using magnetic resonance imaging and anti-citrullinated protein antibody, anti-RA33 and RF autoantibody status

Ball, E. M. A., Tan, A. L., Fukuba, E., McGonagle, D., Grey, A., Steiner, G., Bell, A. L. & Rooney, M. R., Oct 2014, In : Rheumatology. 53, 10, p. 1835-1843 9 p.

Research output: Contribution to journalArticle

Autoantibodies Predictive of Uveitis in Juvenile Idiopathic Arthritis (Aperture): a proof of concept study

Gibson, D., Qiu, J., Finnegan, S., Mendoza, EA., Barker, K., McAllister, K., Labaer, J. & Rooney, M., 2014, p. Rheumatology (2014) 53 (suppl 3): iii2.

Research output: Contribution to conferenceOther

28 Citations (Scopus)

Plasma IL-6 levels correlate with clinical and ultrasound measures of arthritis in patients with systemic lupus erythematosus

Ball, EMA., Gibson, DS., Bell, AL. & Rooney, MR., 01 Jan 2014, In : Lupus. 23, 1, p. 46-56

Research output: Contribution to journalArticle

Systemic Lupus Erythematosus
Arthritis
Interleukin-6
Tumor Necrosis Factor-alpha
Joints
5 Citations (Scopus)
137 Downloads (Pure)

Synovial membrane protein expression differs between juvenile idiopathic arthritis subtypes in early disease

Finnegan, S., Robson, J., Scaife, C., McAllister, C., Pennington, S. R., Gibson, D. S. & Rooney, M. E., Jan 2014, In : Arthritis Research & Therapy. 16, 1, 12 p., R8.

Research output: Contribution to journalArticle

Open Access
File
Juvenile Arthritis
Synovial Membrane
Membrane Proteins
Proteins
Proteome
2012
23 Citations (Scopus)
86 Downloads (Pure)

Circulating and synovial antibody profiling of juvenile arthritis patients by nucleic acid programmable protein arrays.

Gibson, D. S., Qiu, J., Mendoza, E. A., Barker, K., Rooney, M. E. & LaBaer, J., 17 Apr 2012, In : Arthritis research. 14, R77, 12 p.

Research output: Contribution to journalArticle

Open Access
File
Protein Array Analysis
Juvenile Arthritis
Nucleic Acids
Antibodies
Joints

Glycosylation of Vitamin D Binding Protein Reduced in Juvenile Idiopathic Arthritis Patients At Risk of Disease Extension.

Gibson, D., Finnegan, S., Manning, G., Duncan, M., Pennington, S., Moore, T. L. & Rooney, M., 2012, p. Arthritis Rheum 2012;64 Suppl 10 :321.

Research output: Contribution to conferenceAbstract

Vitamin D-Binding Protein
Juvenile Arthritis
Glycosylation
Synovial Fluid
Proteome
14 Citations (Scopus)

Hypermobility and musculoskeletal pain in children: a systematic review

McCluskey, G., O'Kane, E., Hann, D., Weekes, J. & Rooney, M., Oct 2012, In : Scandinavian journal of rheumatology. 41, 5, p. 329-38 10 p.

Research output: Contribution to journalArticle

Musculoskeletal Pain
Odds Ratio
Arthralgia
Meta-Analysis
Confidence Intervals
13 Citations (Scopus)
151 Downloads (Pure)

Vitamin D binding protein isoforms as candidate predictors of disease extension in childhood arthritis

Gibson, D. S., Newell, K., Evans, A. N., Finnegan, S., Manning, G., Scaife, C., McAllister, C., Pennington, S. R., Duncan, M. W., Moore, T. L. & Rooney, M. E., 18 Sep 2012, In : Journal of proteomics. 75, 17, p. 5479-5492 14 p.

Research output: Contribution to journalArticle

Open Access
File
Vitamin D-Binding Protein
Arthritis
Protein Isoforms
Juvenile Arthritis
Synovial Fluid
2011
27 Citations (Scopus)

Biomarkers in rheumatology, now and in the future.

Gibson, D., Rooney, M., Finnegan, S., Qiu, J., Thompson, D. C., Labaer, J., Pennington, S. R. & Duncan, M. W., Mar 2011, In : Rheumatology (Oxford, England). 51, 3, p. 423-433 11 p., ker358.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Synovial membrane immunohistology in early untreated juvenile idiopathic arthritis: differences between clinical subgroups

Finnegan, S., Clarke, S., Gibson, D., McAllister, C. & Rooney, M., Oct 2011, In : Annals of the Rheumatic Diseases. 70, 10, p. 1842-1850 9 p.

Research output: Contribution to journalArticle

T-cells
Juvenile Arthritis
Synovial Membrane
Biopsy
Membranes

Validation of Protein Biomarkers to Advance the Management of Autoimmune Disorders. Autoimmune Disorders: Current concepts & advances from bedside to mechanistic insights

Gibson, D., Finnegan, S., Pennington, S., Qiu, J., Baer, J. L., Rooney, M. & Duncan, M., Nov 2011, InTech . 28 p.

Research output: Book/ReportBook

2010
19 Citations (Scopus)

Diagnostic and prognostic biomarker discovery strategies for autoimmune disorders.

Gibson, D., Banha, J., Penque, D., Costa, L., Conrads, T. P., Cahill, D. J., O\'Brien, J. K. & Rooney, M., 18 Apr 2010, In : Journal of proteomics. 73, 6, p. 1045-1060 16 p.

Research output: Contribution to journalArticle

Biomarkers
Autoimmune Diseases
Proteomics
Clinical laboratories
Therapeutics

INCREASED VITAMIN D BINDING PROTEIN EXPRESSION IN JIA PATIENTS SUFFERING DISEASE EXTENSION

Gibson, D., Pascoli, L., McAlilister, C., Scaife, C., Dunn, M., Pennington, S. & Rooney, M., Apr 2010, In : Rheumatology. 49, p. I87-I87 1 p.

Research output: Contribution to journalArticle

KNEE JOINT IN JIA: A PROSPECTIVE EVALUATION OF CLINICAL EXAMINATION, ULTRASOUND AND MRI ASSESSMENT. A NEWLY DEVELOPED KNEE MRI SCORING SYSTEM IN JIA

Pascoli, L., Napier, W. M., Wray, R., Mc Carron, M., Mc Allister, C. & Rooney, M., Apr 2010, In : Rheumatology. 49, p. I86-I87 2 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

Prospective Evaluation of Clinical and Ultrasound Findings in Ankle Disease in Juvenile Idiopathic Arthritis: Importance of Ankle Ultrasound

Pascoli, L., Wright, S., McAllister, M. & Rooney, M., Nov 2010, In : The Journal of rheumatology. 37 (11), 11, p. 2409-2414 6 p.

Research output: Contribution to journalArticle

Juvenile Arthritis
Ankle
Tendons
Subtalar Joint
Ankle Joint
50 Citations (Scopus)

The Paediatric Rheumatology International Trials Organisation provisional criteria for the evaluation of response to therapy in juvenile dermatomyositis.

Ruperto, N., Pistorio, A., Ravelli, A., Rider, L. G., Pilkington, C., Oliveira, S., Wulffraat, N. V., Rooney, M., Pachman, L. M., Wallace, C., Hashkes, P., Lovell, D. J., Giannini, E. H., Martini, A. & The, F., Jun 2010, In : Arthritis Care and Research. 62(11), 11, p. 1533-1541 9 p.

Research output: Contribution to journalArticle

Rheumatology
Muscle Strength
Pediatrics
Myositis
Reproducibility of Results
2009
47 Citations (Scopus)

Ankle disease in juvenile idiopathic arthritis: ultrasound findings in clinically swollen ankles

Rooney, M., McAllister, C. & Burns, J. F. T., Aug 2009, In : Journal of Rheumatology. 36, 8, p. 1725-1729 5 p.

Research output: Contribution to journalArticle

Tenosynovitis
Synovitis
Juvenile Arthritis
Ankle
Ankle Joint
22 Citations (Scopus)

Comparative analysis of synovial fluid and plasma proteomes in juvenile arthritis - Proteomic patterns of joint inflammation in early stage disease

Gibson, D., Blelock, S., Curry, J., Finnegan, S., Healy, A., Scaife, C., McAllister, K., Pennington, S., Dunn, M. & Rooney, M., 02 May 2009, In : Journal of proteomics. 72, 4, p. 656-676 21 p.

Research output: Contribution to journalArticle

Juvenile Arthritis
Synovial Fluid
Proteome
Proteomics
Joints
18 Citations (Scopus)

Proteomic analysis of circulating immune complexes in juvenile idiopathic arthritis reveals disease-associated proteins

Low, J. M., Chauhan, A. K., Gibson, D., Zhu, M. M., Chen, S. X., Rooney, M., Ombrello, M. J. & Moore, T. L., 2009, In : PROTEOMICS CLINICAL APPLICATIONS. 3, 7, p. 829-840 12 p.

Research output: Contribution to journalArticle

Juvenile Arthritis
Antigen-Antibody Complex
Proteomics
Proteome
Proteins
18 Citations (Scopus)

Stratification and Monitoring of Juvenile Idiopathic Arthritis Patients by Synovial Proteome Analysis

Gibson, D. S., Finnegan, S., Jordan, G., Scaife, C., Brockbank, S., Curry, J., McAllister, K., Pennington, S., Dunn, M. & Rooney, M. E., 04 Dec 2009, In : Journal of Proteome Research. 8, 12, p. 5601-5609 9 p.

Research output: Contribution to journalArticle

Juvenile Arthritis
Proteome
Synovial Fluid
Monitoring
Fluids
2008

Juvenile idiopathic arthritis: Synovial predictors of outcome

Pascoli, L., Blelock, S., Mc Allister, C., Clarke, S., Gibson, D. & Rooney, M., Aug 2008, In : Rheumatology. 47, p. II26-II26 1 p.

Research output: Contribution to journalArticle

Synovial fluid proteome expression patterns segregate juvenile idiopathic arthritis patients

Gibson, D., Blelock, S., Curry, J., Finnegan, S., Healy, A., Scaife, C., McAllister, C., Pennington, S., Dunn, M. & Rooney, M., Apr 2008, In : Rheumatology (Oxford, England). 47, p. II27-II27 1 p.

Research output: Contribution to journalArticle

The role of growth factors and osteoclast mediators in the pathogenesis of early untreated juvenile idiopathic arthritis (JIA)

Blelock, S., Gibson, D., Clarke, S., McAllister, C., Jordan, G. & Rooney, M., Apr 2008, In : Rheumatology (Oxford, England). 47, p. II4-II4 1 p.

Research output: Contribution to journalMeeting abstract

Validation of JIA patient stratification by synovial proteome profiles in an independent cohort

Gibson, D., Rooney, M., Rosenkranz, M. E., Hirsch, R., Scaife, C., Dunn, M. & Pennington, S., 2008, In : Arthritis and Rheumatism. 58, p. S218-S218 1 p.

Research output: Contribution to journalArticle

2007

Fingerprinting the synovial proteome to stratify juvenile idiopathic arthritis patients

Gibson, D., Blelock, S., Finnegan, S., Curry, J., Healy, A., Scaife, C., McAllister, C., Pennington, S., Dunn, M. & Rooney, M., Jun 2007, In : Annals of the Rheumatic Diseases. 66, p. 112-112 1 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

The human synovial fluid proteome: A key factor in the pathology of joint disease

Gibson, D. & Rooney, M., Aug 2007, In : PROTEOMICS CLINICAL APPLICATIONS. 1, 8, p. 889-899 11 p.

Research output: Contribution to journalArticle

Joint Diseases
Synovial Fluid
Pathology
Proteome
Proteomics

The immunopathology of early untreated juvenile idiopathic arthritis

Blelock, S., Gibson, D., Clarke, S., McAllister, C. & Rooney, M., Jun 2007, In : Annals of the Rheumatic Diseases. 66, p. 559-559 1 p.

Research output: Contribution to journalMeeting abstract

2006

Biomarkers of disease progression in Juvenile idiopathic arthritis patients

Gibson, D., Blelock, S., Curry, J., Healy, A., Scaife, C., McAllister, C., Pennington, S., Dunn, M. & Rooney, M., 2006, In : Molecular and Cellular Proteomics. 5, p. S138-S138 1 p.

Research output: Contribution to journalArticle

Identification of proteomic biomarkers to predict progression in juvenile idiopathic arthritis.

Gibson, D., Blelock, S., Curry, J., Healy, A., Dunn, M., Pennington, S. & Rooney, M., Nov 2006, In : Arthritis and Rheumatism. 54, p. S693-S693 1 p.

Research output: Contribution to journalArticle

586 Citations (Scopus)

Juvenile idiopathic arthritis: Joint destruction vs joint repair. Clinical and histological findings in early untreated disease.

Blelock, S., McAllister, C., Gibson, D., Clarke, S. & Rooney, M., 2006, In : Arthritis and Rheumatism. 54, p. S692-S692 1 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Musculoskeletal ultrasound training in rheumatology: the belfast experience

Taggart, A., Filippucci, E., Wright, G., Rooney, M., Bell, A., Cairns, A., Meenagh, G., Pendleton, A., Wright, S., Grey, A. & Grassi, W., Jan 2006, In : Rheumatology. 45, 1, p. 102-105 4 p.

Research output: Contribution to journalArticle

Proteomic identification of a biomarker cluster associated with recurrent joint inflammation in Juvenile Idiopathic Arthritis

Gibson, D. S., Blelock, S., Brockbank, S., Curry, J., Healy, A., McCallister, C. & Rooney, M., May 2006.

Research output: Contribution to conferencePaper

Proteomic identification of a biomarker cluster associated with recurrent joint inflammation in Juvenile Idiopathic Arthritis

Gibson, D., Blelock, S., Brockbank, S., Curry, J., Healy, A., McCallister, C. & Rooney, M., May 2006, In : Rheumatology (Oxford, England). 45, p. I115-I115 1 p.

Research output: Contribution to journalArticle

2005

Analysis of the synovial proteome in juvenile idiopathic arthritis

Gibson, D., Blelock, S. & Rooney, M., Apr 2005, In : Rheumatology (Oxford, England). 44, p. I43-I43 1 p.

Research output: Contribution to journalArticle

Proteomic validation of a biomarker cluster associated with chronic joint inflammation in juvenile idiopathic arthritis.

Gibson, D., Blelock, S., Brockbank, S., Curry, J., Healy, A. & Rooney, M., Nov 2005, In : Arthritis and Rheumatism. 52, p. S417-S418 2 p.

Research output: Contribution to journalArticle

2003
42 Citations (Scopus)
129 Downloads (Pure)

Polymorphims in the Interferon-y/Interleukin 26 Gene Region Contribute to Sex Bias in Susceptibility to Rheumatoid Arthritis

Vandenbroeck, K., Cunningham, S., Goris, A., Alloza, I., Heggarty, S., Graham, C., Bell, A. & Rooney, M., Oct 2003, In : Arthritis and Rheumatism. 48, 10, p. 2773-2778 6 p.

Research output: Contribution to journalArticle

File
Sexism
Interleukins
Interferons
Rheumatoid Arthritis
Genes