Maeliosa McCrudden

Dr

  • Room 01.006 - Pharmacy & MCI

    United Kingdom

20082020

Research output per year

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Research Output

2020

Evaluation of the clinical impact of repeat application of hydrogel-forming microneedle array patches

Al-Kasasbeh, R., Brady, A. J., Courtenay, A. J., Larrañeta, E., McCrudden, M. T. C., O'Kane, D., Liggett, S. & Donnelly, R. F., 26 Feb 2020, In : Drug Delivery and Translational Research.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
24 Downloads (Pure)

Hydrogel-forming microneedle arrays as a therapeutic option for transdermal esketamine delivery

Courtenay, A. J., McAlister, E., McCrudden, M. T. C., Vora, L., Steiner, L., Levin, G., Levy-Nissenbaum, E., Shterman, N., Kearney, M-C., McCarthy, H. O. & Donnelly, R. F., 19 Mar 2020, In : Journal of controlled release : official journal of the Controlled Release Society. 322, p. 177-186 10 p.

Research output: Contribution to journalArticle

Open Access
File
38 Downloads (Pure)
6 Downloads (Pure)
2019

Control of Klebsiella pneumoniae infection in mice using dissolving microarray patches containing gentamicin

Rodgers, A. M., McCrudden, M. T. C., Courtenay, A. J., Kearney, M-C., Edwards, K. L., Ingram, R. J., Bengoechea, J. & Donnelly, R. F., 01 May 2019, In : Antimicrobial Agents and Chemotherapy. 63, 5, p. e02612-e02618 7 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
139 Downloads (Pure)

Design, Formulation, and Evaluation of Novel Dissolving Microarray Patches Containing Rilpivirine for Intravaginal Delivery

McCrudden, M., Larrañeta, E., Clark, A., Jarrahian, C., Rein-Weston, A., Creelman, B., Moyo, Y., Lachau-Durand, S., Niemeijer, N., Williams, P., McCarthy, H. O., Zehrung, D. & Donnelly, R. F., 06 Mar 2019, In : Advanced Healthcare Materials. 0, 0, p. 1801510 1 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
151 Downloads (Pure)
Open Access
File
8 Citations (Scopus)
107 Downloads (Pure)

Novel Hydrogel-Forming Microneedle Array for Intradermal Vaccination in Mice Using Ovalbumin as a Model Protein Antigen

Courtenay, A. J., Rodgers, A. M., McCrudden, M. T. C., McCarthy, H. O. & Donnelly, R. F., 07 Jan 2019, In : Molecular Pharmaceutics. 16, 1, p. 118-127 10 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
80 Downloads (Pure)
Open Access
File
4 Citations (Scopus)
69 Downloads (Pure)

University and School Collaboration to Promote STEM Subjects

Kearney, M-C., Courtenay, A., Quinn, H., Hampson, P. & McCrudden, M., Jan 2019.

Research output: Contribution to conferencePoster

2018

Design, formulation and evaluation of novel dissolving microarray patches containing a long-acting rilpivirine nanosuspension

McCrudden, M. T. C., Larrañeta, E., Clark, A., Jarrahian, C., Rein-Weston, A., Lachau-Durand, S., Niemeijer, N., Williams, P., Haeck, C., McCarthy, H. O., Zehrung, D. & Donnelly, R. F., 01 Dec 2018, In : Journal of Controlled Release. 292, p. 119-129

Research output: Contribution to journalArticle

Open Access
File
14 Citations (Scopus)
251 Downloads (Pure)
Open Access
File
7 Citations (Scopus)
254 Downloads (Pure)

Effects of LL-37 on Gingival Fibroblasts: A Role in Periodontal Tissue Remodeling?

McCrudden, M. T. C., O'Donnell, K., Irwin, C. R. & Lundy, F. T., 23 Jul 2018, In : Vaccines. 6, 3, 11 p., 44.

Research output: Contribution to journalArticle

Open Access
File
139 Downloads (Pure)
Open Access
File
19 Citations (Scopus)
257 Downloads (Pure)

Microneedle-Mediated Transdermal Delivery of Bevacizumab

Courtenay, A. J., McCrudden, M. T. C., McAvoy, K. J., McCarthy, H. O. & Donnelly, R. F., 06 Aug 2018, In : Molecular Pharmaceutics. 15, 8, p. 3545-3556

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
136 Downloads (Pure)
2017

Characterisation of eppin function: expression and activity in the lung

Scott, A., Glasgow, A., Small, D., Carlile, S., McCrudden, M., McLean, D., Brown, R., Doherty, D., Lundy, F., Hamid, U., O'Kane, C., McAuley, D., Brodlie, M., Tunney, M., Elborn, J., Irwin, C., Timson, D., Taggart, C. & Weldon, S., 13 Jul 2017, In : European Respiratory Journal. 50, 1, 1601937.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
129 Downloads (Pure)

Engaging Pre-GCSE Pupils with Research

Cregan, M., McCloskey, K., McCrudden, M. & Hampson, P., 05 Oct 2017.

Research output: Contribution to conferencePaper

Open Access
File
24 Citations (Scopus)
266 Downloads (Pure)
Open Access
File
3 Citations (Scopus)
259 Downloads (Pure)

Microarray patch delivery of a long-acting antiretroviral for HIV prep or treatment.

Jarrahian, C., McCrudden, M., Rein-Weston, A., Creelman, B., Larrañeta, E., Donnelly, R. & Zehrung, D., 2017.

Research output: Contribution to conferencePoster

26 Citations (Scopus)
218 Downloads (Pure)

Transdermal delivery of gentamicin using dissolving microneedle arrays. Potential system for treating neonatal sepsis.

Gonzalez Vazquez, P., Larrañeta, E., McCrudden, M., Jarrahian, C., Rein-Weston, A., Quintanar-Solares, M., Zehrung, D., McCarthy, H. & Donnelly, R., 2017.

Research output: Contribution to conferencePoster

Transdermal delivery of gentamicin using dissolving microneedle arrays for potential treatment of neonatal sepsis

González-Vázquez, P., Larrañeta, E., McCrudden, M. T. C., Jarrahian, C., Rein-Weston, A., Quintanar-Solares, M., Zehrung, D., McCarthy, H., Courtenay, A. J. & Donnelly, R. F., 25 Jul 2017, In : Journal of Controlled Release.

Research output: Contribution to journalArticle

Open Access
File
44 Citations (Scopus)
295 Downloads (Pure)
2016

A facile system to evaluate in vitro drug release from dissolving microneedle arrays

Larrañeta, E., Stewart, S., Fallows, S. J., Birkhäuer, L. L., McCrudden, M. T. C., Woolfson, A. D. & Donnelly, R. F., 30 Jan 2016, In : International Journal of Pharmaceutics. 497, 1-2, p. 62-69 8 p.

Research output: Contribution to journalArticle

Open Access
File
22 Citations (Scopus)
423 Downloads (Pure)

Biodentine Reduces Tumor Necrosis Factor Alpha-induced TRPA1 Expression in Odontoblastlike Cells

El Karim, I. A., McCrudden, M. T. C., McGahon, M. K., Curtis, T. M., Jeanneau, C., Giraud, T., Irwin, C. R., Linden, G. J., Lundy, F. T. & About, I., Apr 2016, In : Journal of Endodontics. 42, 4, p. 589-595 7 p.

Research output: Contribution to journalArticle

File
8 Citations (Scopus)
332 Downloads (Pure)

Delivery of rilpivirine from dissolving MN arrays for HIV pre-exposure prophylaxis

McCrudden, M., Larrañeta, E., Jarrahian, C., Zehrung, D., Rein-Weston, A. & Donnelly, R., 2016.

Research output: Contribution to conferencePoster

Hydrogel-forming microneedle arrays made from light-responsive materials for on-demand transdermal drug delivery

Hardy, J. G., Larrañeta, E., Donnelly, R. F., McGoldrick, N., Migalska, K., McCrudden, M. T. C., Irwin, N. J., Donnelly, L. & McCoy, C. P., 07 Mar 2016, In : Molecular Pharmaceutics. 13, 3, p. 907-914 8 p.

Research output: Contribution to journalArticle

Open Access
File
37 Citations (Scopus)
379 Downloads (Pure)

Hydrogel-forming microneedle patches for gentamicin delivery: A novel approach in the treatment of neonatal sepsis.

Gonzalez Vazquez, P., McCrudden, M., Larrañeta, E., Jarrahian, C., Zehrung, D., Rein-Weston, A., Quintanar-Solares, M. & Donnelly, R., 2016.

Research output: Contribution to conferencePoster

Microneedles: A New Frontier in Nanomedicine Delivery

Larrañeta, E., McCrudden, M. T. C., Courtenay, A. & Donnelly, R. F., May 2016, In : Pharmaceutical Research. 33, 5, p. 1055-1073 19 p.

Research output: Contribution to journalReview article

Open Access
File
108 Citations (Scopus)
418 Downloads (Pure)

Stimuli-Responsive Microneedle Arrays For On-Demand Drug Delivery

Larrañeta, E., Hardy, J., McCoy, C., McGoldrick, N., Migalska, K., McCrudden, M., Donnelly, L. & Donnelly, R., 2016.

Research output: Contribution to conferencePoster

Transcending epithelial and intracellular biological barriers; a prototype DNA delivery device

McCaffrey, J., McCrudden, C. M., Ali, A. A., Massey, A. S., McBride, J. W., McCrudden, M. T. C., Vicente-Perez, E. M., Coulter, J. A., Robson, T., Donnelly, R. F. & McCarthy, H. O., 28 Mar 2016, In : Journal of controlled release : official journal of the Controlled Release Society. 226, p. 238-47 10 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Transdermal Delivery of Iron Using Soluble Microneedles: Dermal Kinetics and Safety

Modepalli, N., Shivakumar, H. N., McCrudden, M. T. C., Donnelly, R. F., Banga, A. & Murthy, S. N., 01 Mar 2016, In : Journal of Pharmaceutical Sciences. 105, 3, p. 1196-1200

Research output: Contribution to journalArticle

9 Citations (Scopus)

Two-step casting of dissolving MN arrays for use in the sustained release of rilpivirine for HIV pre-exposure prophylaxis.

McCrudden, M., Larrañeta, E., Jarrahian, C., Zehrung, D., Rein-Weston, A. & Donnelly, R., 2016.

Research output: Contribution to conferencePoster

2015

Considerations in the sterile manufacture of polymeric microneedle arrays

McCrudden, M. T. C., Zaid Alkilani, A., Courtenay, A., McCrudden, C. M., McCloskey, B., Walker, C., Alshraiedeh, N., Lutton, R. E. M., Gilmore, B. F., Woolfson, A. D. & Donnelly, R. F., Feb 2015, In : Drug Delivery and Translational Research. 5, 1, p. 3-14 12 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)
Open Access
File
45 Citations (Scopus)
351 Downloads (Pure)

Laser-engineered dissolving microneedle arrays for protein delivery: potential for enhanced intradermal vaccination

McCrudden, M. T. C., Torrisi, B. M., Al-Zahrani, S., McCrudden, C. M., Zaric, M., Scott, C. J., Kissenpfennig, A., McCarthy, H. O. & Donnelly, R. F., Mar 2015, In : Journal of Pharmacy and Pharmacology. 67, 3, p. 409-425 17 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Microneedle applications in improving skin appearance

McCrudden, M. T. C., McAlister, E., Courtenay, A., González-Vázquez, P., Raj Singh, T. R. & Donnelly, R. F., Aug 2015, In : Experimental dermatology. 24, 8, p. 561-566 6 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

TNF alpha-Induced p38MAPK Activation Regulates TRPA1 and TRPV4 Activity in Odontoblast-Like Cells

El Karim, I., McCrudden, M. T. C., Linden, G. J., Abdullah, H., Curtis, T. M., McGahon, M., About, I., Irwin, C. & Lundy, F. T., Nov 2015, In : American Journal of Pathology. 185, 11, p. 2994-3002 9 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

TNFα-induced p38 MAPK activation regulates TRPA1 and TRPV4 activity in human odontoblast-like cells

El Karim, I., McCrudden, M., Linden, G., Curtis, T., McGahon, M., Abdullah, H., About, I., Irwin, C. & Lundy, F., 2015, In : Journal of Dental Research.

Research output: Contribution to journalMeeting abstract

Transdermal drug delivery: Innovative pharmaceutical developments based on disruption of the barrier properties of the stratum corneum

Alkilani, A. Z., McCrudden, M. T. C. & Donnelly, R. F., 22 Oct 2015, In : Pharmaceutics. 7, 4, p. 438-470 33 p.

Research output: Contribution to journalReview article

Open Access
File
149 Citations (Scopus)
6 Downloads (Pure)
2014

Antimicrobial and immunomodulatory properties of PGLa-AM1, CPF-AM1, and magainin-AM1: Potent activity against oral pathogens

McLean, D. T. F., McCrudden, M. T. C., Linden, G. J., Irwin, C. R., Conlon, J. M. & Lundy, F. T., Nov 2014, In : Regulatory Peptides. 194-195, p. 63-68 6 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Design and physicochemical characterisation of novel dissolving polymeric microneedle arrays for transdermal delivery of high dose, low molecular weight drugs

McCrudden, M. T. C., Alkilani, A. Z., McCrudden, C. M., McAlister, E., McCarthy, H. O., Woolfson, A. D. & Donnelly, R. F., 28 Apr 2014, In : Journal of Controlled Release. 180, p. 71-80 10 p.

Research output: Contribution to journalArticle

Open Access
File
91 Citations (Scopus)
400 Downloads (Pure)

Hydrogel-Forming Microneedle Arrays Can Be Effectively Inserted in Skin by Self-Application: A Pilot Study Centred on Pharmacist Intervention and a Patient Information Leaflet

Donnelly, R. F., Moffatt, K., Alkilani, A. Z., Vicente-Pérez, E. M., Barry, J., McCrudden, M. T. C. & Woolfson, A. D., Aug 2014, In : Pharmaceutical Research. 31, 8, p. 1989-1999

Research output: Contribution to journalArticle

67 Citations (Scopus)

Hydrogel-Forming Microneedles Increase in Volume During Swelling in Skin, but Skin Barrier Function Recovery is Unaffected

Donnelly, R. F., Mooney, K., McCrudden, M. T. C., Vicente-Pérez, E. M., Belaid, L., González-Vázquez, P., McElnay, J. C. & Woolfson, A. D., May 2014, In : Journal of Pharmaceutical Sciences. 103, 5, p. 1478-1786 9 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Hydrogel-Forming Microneedles Prepared from ‘‘Super Swelling’’ Polymers Combined with Lyophilised Wafers for Transdermal Drug Delivery

Donnelly, R. F., McCrudden, M. T. C., Zaid Alkilani, A., Larrañeta, E., McAlister, E., Courtenay, A., Kearney, M-C., Singh, T. R. R., McCarthy, H. O., Kett, V. L., Caffarel-Salvador, E., Al-Zahrani, S. & Woolfson, A. D., 31 Oct 2014, In : PLoS ONE. 9, 10, 12 p., e111547.

Research output: Contribution to journalArticle

Open Access
File
102 Citations (Scopus)
859 Downloads (Pure)
21 Citations (Scopus)
9 Citations (Scopus)

The role of microneedles for drug and vaccine delivery

Quinn, H. L., Kearney, M-C., Courtenay, A., McCrudden, M. T. C. & Donnelly, R. F., Nov 2014, In : Expert Opinion on Drug Delivery. 11, 11, p. 1769-80 12 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)
2013

Hydrogel-forming microneedle arrays exhibit antimicrobial properties: Potential for enhanced patient safety

Donnelly, R. F., Singh, T. R. R., Alkilani, A. Z., McCrudden, M. T. C., O' Neill, S., O'Mahony, C., Armstrong, K., McLoone, N., Kole, P. & Woolfson, A. D., 15 Jul 2013, In : International Journal of Pharmaceutics. 451, 1-2, p. 76-91

Research output: Contribution to journalArticle

52 Citations (Scopus)