No photo of Maeve Rea
  • Room 02.031 - Whitla Medical Building Block 97B MBC Site

    United Kingdom

Willing to speak to media

19942019
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Personal profile

Interests

Classical Music, I listen and play piano and organ

Art and have tried my hand at painting

Walking and enjoying beautiful places

Research Statement

Background

My research work has centred around identifying factors that may contribute to ' successful ageing ', and I am particularly interested in the ' oldest old' , and the approximately 15% of 90 year olds, who seem to be ' ageing 'slowly' with the combination of long 'lifespan ' but also ' healthspan '.

My research hypothesis has been around demonstrating evidence that 'elite' 90 year olds who have ' aged both long and well' and who seem to be in robust health, should demonstrate a competent immune system, good cardiovascular risk profiles, have facilitatory genes, and a good nutritional profile .

BELFAST Study 1994-currently

I set up the B elfast E lderly L ongitudinal F ree-living A geing ST udy ( BELFAST ) , and recruited a large number of ' elite ' community living 90 year old (nonagenarians) as well as 80 year olds (octogenarians), who at recruitment met very robust health and cognition criteria.

The BELFAST study has produced a regular output of publications in the ageing field, with a particular emphasis on immunological, cardiovascular risk factors, nutrition and genetics and the interaction between genetic and life-style factors, as a contributor/s to 'healthy ageing'.

The BELFAST study has the acronym BELFAST, which both fits the study aims, but also helps our research at Queens University, to be remembered nationally and internationally.

EU funded GeHA Project 2004-2010

I became a Principal Investigator in EU-funded Ge netics of H ealthy A geing ( GeHA ) in 2004 and the GeHA research collaboration is unique in that it is collecting DNA and life-style information from 3000 brothers and sisters (sibling pairs) over the age of 90 years, who lived in 11 countries across Europe.

Finding and recruiting 2 siblings over 90 years was very challenging and time-consuming, since sibling pairs over 90 years of age, represent only 0.01% of the population, even assuming both siblings agreed to be recruited.

The Ethical differences and constraints made for further challenges, but provided important learning about consent, biobanking and ongoing responsibilities.

Recently, the mitochondrial genome of 1000 sibling pairs over 90 years of age has been sequenced by our international partner at the Beiing Genomics Institute and the output from the Linkage analysis from Leiden Genetic Centre is of interest.

ACUME2 and 'Beyond 90 Together' projects

These research collaborations, ACUME2, (an EU funded Socrates project), and ' Beyond 90 together' (Changing Ageing Partnership), have brought my research together into a creative fusion between the Arts and Sciences.

In both the ACUME2 project and ' Beyond 90 together' research projects, the GeHA participants tell us about their lives , in text, in voice and in image.

The outputs from these projects are a book ( Super Vivere: Reflection of Long life and Ageing Well, Rea & Rea, 2011 ), digitial stories and an Exhibition called Super Vivere, which has been at the Naughton Gallery in Queens, in Newcastle University, Poland during 2011, and is planned for London and the Midlands in 2012.

It is hoped these outputs will serve as dissemination tools for the GEHA and BELFAST research projects, as teaching tools for medical and nursing education and as a means of improving societal understanding about ageing.

Teaching

Phase 4 Undergraduate Medicine.

Module Co-ordinator Ageing and Health

*I was ill and unable to teach for 2 semesters 2010-11.

1994- currently

280 undergraduate medical students taught in 6 blocks of 44-46, between 1 September and 30 June each academic year.

42 hours / year for Phase 4 Ageing and Health teaching (direct teaching only.

Introduction and Welcome, Interactive Lectures x2, Ethics Seminar for each of 6 blocks of 44-46 students.

Nutrition Lecture introduced during academic year 2010-11, to increase student's awareness of need for nutritional assessment in patients. Few students had this skill completed in Phase 5 Portfolios.

Speech and Language included in Core Lectures in Week 1 of Ageing and Health Module to ensure that students know about safe swallowing ie after stroke.

Ageing Long and Ageing Well Lecture, includes digital stories ie audio files and photographs of 90 year old subjects (Changing Ageing Partnership Grant. Beyond 90 together). Associated book Super Vivere: Ageing Long Ageing Well. Rea&Rea 2011

Year 1 and 2 Undergraduate Medicine

Portfolio Module

2008-2010

-Supervision of 12-14 students in Year 1 and then the same goup in year 2, in next academic year.

-12 hours for module (direct teaching) meet and greet, explanation of requirements of module semester 1 and semester 2 update meeting

-36 hours (online feedback about portfolios, semester 1, 2 and before submission).

Year 1 -Undergraduate Medical Students

Ethics

1999-currently

Ethical Seminar -8 to 16 students, depending on staff availability.

3- 4 hours

Discussion and case study work, to introduce students to concepts of ethics in medical practice. Feedback session to whole group.

Year 2 Undergraduate Medicine

Communication skills

1999-currently

-10-12 students, 3 hours (direct teaching session)

-preparing brief and students for video session, videoing student interviews, feedback session with students and group.

Year 2 Undergraduate Medical Students.

Clinical Skills

-2002-currently.

-6-7 medical students.

-3 x 10 weeks, 30 hours minimum.

-Bedside case presentation and skills teaching.

Year 3 Undergraduate Medicine

Special Study Modules (SSM)

- Dementia SSM with Dr David Craig

-2006-2010,

6-8 students,

3-4 hours Assessment of SSM with feedback to students.

Year 3 Undergraduate Medicine and BSc students in Therapeutics

Special Study Modules (SSM)

-Therapeutics Module -Dr David Bell.

2002-currently.

6-8 students.

2 hours (direct).

Lecture interactive -Medicines use in Older People.

Final Year Undergraduate Medical Students.

Specialty Clinical Week

2000- currently

-2-4 Medical students x 12 weeks, autumn semester

- revision in geriatric Medicine with bedside teaching, clinic assessment and supervision.

-4-6 hours weekly

Fingerprint Dive into the research topics where Maeve Rea is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Cytokines Medicine & Life Sciences
Meta-Analysis Medicine & Life Sciences
Genotype Medicine & Life Sciences
Aging of materials Chemical Compounds
Mitochondrial DNA Medicine & Life Sciences
Lymphocyte Subsets Medicine & Life Sciences
Blood Pressure Medicine & Life Sciences
Interleukin-2 Receptors Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2004 2004

R6229GRM: GEHA.

Rea, I.

01/08/200413/12/2019

Project: Research

Research Output 1994 2019

Germinal Center
B-Lymphocytes
Antibodies
Lymphopenia
Vaccination

Prompting Medical Students to Self-Assess their Learning Needs during the Ageing and Health Module: A Mixed Methods Study

Kennedy, G., Rea, J. N. M. & Rea, I. M., 02 May 2019, In : Medical Education Online. 24, 1, 12 p., 1579558.

Research output: Contribution to journalArticle

Open Access
File
Medical Students
medical student
Learning
Visual Analog Scale
Students
58 Citations (Scopus)

Age and Age-related Diseases: Role of Inflammation Triggers and Cytokines

Rea, I. M., Gibson, D. S., McGilligan, V., McNerlan, S. E. & Alexander, H. D., 09 Apr 2018, In : Frontiers in immunology. p. 1-28 586.

Research output: Contribution to journalReview article

Open Access
File
Cytokines
Inflammation
Rheumatoid Arthritis
Inflammasomes
Autophagy

Cytokine Expression and Production Changes in Very Old Age

McNerlan, S., Ross, O. & Rea, I. M., 01 Jan 2018, In: Tamas Fulop, Claudio Franceschi, Katsuiku Hirokawa, Graham Pawelec (Eds.), Handbook of Immunosenescence, 1-24, 2018. Springer, p. https://doi.org/10.1007/978-3-319-64597-1_40-1

Research output: Chapter in Book/Report/Conference proceedingChapter

Cytokines
Immune System
Life Style
Inflammation
Phenotype

Living Long and Aging Well: Are Lifestyle Factors the Epigenetic Link in the Longevity Phenotype

Rea, I. M. & Mills, K., 17 Nov 2017, Epigenetics of Aging and Longevity. Moskalev, A. & Vaiserman, A. M. (eds.). Academic Press Inc., Vol. 4. p. 137-152 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

population group
life expectancy
illness
medicine
Disease

Activities 1980 2015

The 2015 Ageing Summit

Maeve Rea (Invited speaker)
10 Feb 201512 Feb 2015

Activity: Talk or presentation typesInvited talk

File

British Society Research into Ageing

Maeve Rea (Invited speaker)
07 Jul 201409 Jul 2014

Activity: Participating in or organising an event typesParticipation in conference

International Symposium: The Challenges of the Biological Research in Aging in the 21st Century: from the cells to the clinics.

Maeve Rea (Invited speaker)
02 Nov 201404 Nov 2014

Activity: Participating in or organising an event typesParticipation in conference

Second International Medical Congress Woman and Man: Healthy Ageing

Maeve Rea (Keynote/plenary speaker)
10 Oct 201411 Oct 2014

Activity: Participating in or organising an event typesParticipation in conference

EuroScion Obesity Summit 2014

Maeve Rea (Invited speaker)
01 Apr 2014

Activity: Participating in or organising an event typesParticipation in conference