Projects per year
Personal profile
Interests
I trained in haematology and general medicine in Belfast and then in the Royal Postgraduate Medical school, Hammersmith Hospital. I was appointed senior lecturer in 1991 and have been an active researcher and clinician in haematological malignancy in Belfast since that time.
Other
Key Words
Myeloproliferative Disorders, Polycythaemia Vera, Idiopathic Erythrocytosis, Acute Myeloid Leukaemia, Chronic Myeloid Leukaemia and Clinical Trials.
Grants
I have received funding for Clinical Training Fellows from the Medical Research Council, Leukaemia Research Fund and the Research and Development Office Northern Ireland.
Myeloproliferative Disorders, Polycythaemia Vera, Idiopathic Erythrocytosis, Acute Myeloid Leukaemia, Chronic Myeloid Leukaemia and Clinical Trials.
Grants
I have received funding for Clinical Training Fellows from the Medical Research Council, Leukaemia Research Fund and the Research and Development Office Northern Ireland.
Research Statement
Research
My main research interests are in myeloproliferative disorders, acute myeloid leukaemia and chronic myeloid leukaemia. I have an active clinical practice and collaborate with scientists looking at the pathogenesis of the myeloproliferative disorders and in particular investigations of patients with idiopathic erythrocytosis. I also work on the pathogenesis and treatment of Acute Myeloid Leukaemia and Chronic Myeloid Leukaemia.
My main research interests are in myeloproliferative disorders, acute myeloid leukaemia and chronic myeloid leukaemia. I have an active clinical practice and collaborate with scientists looking at the pathogenesis of the myeloproliferative disorders and in particular investigations of patients with idiopathic erythrocytosis. I also work on the pathogenesis and treatment of Acute Myeloid Leukaemia and Chronic Myeloid Leukaemia.
Clinical Trials
With the clinical trials unit we have a number of phase three and phase two trials in the areas of acute myeloid leukaemia and chronic myeloid leukaemia and myeloproliferative disorders. We continually investigate for new and improved treatments in these disorders.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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R2409CPH: Myeloproliferative neoplasmS: An In-depth Case-Control (MOSAICC) Study
31/05/2017 → …
Project: Research
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R1785CNR: The role of c-FLIP in regulating response to chemotherapy in AM Leukeumia
01/08/2006 → …
Project: Research
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R2541CPH: Myeloproliferative neoplasmS: An In-depth Case-Control (MOSAICC) study
19/11/2018 → 31/05/2021
Project: Research
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Analysis of real-world data demonstrating the efficacy of current management of polycythaemia vera in attaining and maintaining therapeutic haematocrit
Buckley, F. D., Arnold, C., Brass, D., Catherwood, M. & McMullin, M. F., 08 Sep 2023, (Early online date) In: Irish Journal of Medical Science. 4 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Downloads (Pure) -
A phase IV study evaluating QT interval, pharmacokinetics, and safety following fractionated dosing of gemtuzumab ozogamicin in patients with relapsed/refractory CD33-positive acute myeloid leukemia
Montesinos, P., Kota, V., Brandwein, J., Bousset, P., Benner, R. J., Vandendries, E., Chen, Y. & McMullin, M. F., 09 Mar 2023, (Early online date) In: Cancer Chemotherapy and Pharmacology. 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Downloads (Pure) -
A randomised evaluation of low-dose Ara-C plus pegylated recombinant arginase BCT-100 versus low dose Ara-C in older unfit patients with acute myeloid leukaemia: Results from the LI-1 trial
Mussai, F., De Santo, C., Cheng, P., Thomas, I. F., Ariti, C., Upton, L., Scarpa, U., Stavrou, V., Sydenham, M., Burnett, A. K., Knapper, S. K., Mehta, P., McMullin, M. F., Copland, M., Russell, N. H. & Dennis, M., Mar 2023, In: British Journal of Haematology. 200, 5, p. 573-578 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile77 Downloads (Pure) -
Characterization of genetic variants in the EGLN1/PHD2 gene identified in a European collection of patients with erythrocytosis
Delamare, M., Le Roy, A., Pacault, M., Schmitt, L., Garrec, C., Maaziz, N., Myllykoski, M., Rimbert, A., Karaghiannis, V., Aral, B., Catherwood, M., Airaud, F., Mansour-Hendili, L., Hoogewijs, D., Peroni, E., Idriss, S., Lesieur, V., Caillaud, A., Si-Tayeb, K., Chariau, C., & 22 others, 15 Jun 2023, (Early online date) In: HAEMATOLOGICA.Research output: Contribution to journal › Article › peer-review
Open Access -
Epigenetics in myeloproliferative neoplasms
Greenfield, G. & McMullin, M. F., 13 Jul 2023, In: Frontiers in Oncology. 13, 9 p., 1206965.Research output: Contribution to journal › Review article › peer-review
Open AccessFile8 Downloads (Pure)
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Cancers (Journal)
Mary Frances McMullin (Peer reviewer)
01 May 2020Activity: Publication peer-review and editorial work types › Editorial activity
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JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY (Journal)
Mary Frances McMullin (Associate editor)
01 Jan 2008Activity: Publication peer-review and editorial work types › Publication peer-review
Press/Media
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MPDLife June 2014
Lesley Anderson & Mary Frances McMullin
01/06/2014
1 item of Media coverage
Press/Media: Public Engagement Activities
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MPDLife November 2013
Lesley Anderson & Mary Frances McMullin
01/11/2013
1 item of Media coverage
Press/Media: Public Engagement Activities
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MPDLife March 2013
Lesley Anderson & Mary Frances McMullin
01/03/2013
1 item of Media coverage
Press/Media: Public Engagement Activities
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MPDLife May 2012
Lesley Anderson & Mary Frances McMullin
01/05/2012
1 item of Media coverage
Press/Media: Public Engagement Activities
Impact
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Identifying Patients with Rare Forms of Erythrocytosis
Mary Frances McMullin (Participant), Terence Lappin (Participant) & Anne Hughes (Participant)
Impact: Health Impact, Quality of Life Impact