1988 …2020

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2020

Modifiable lifestyle and medical risk factors associated with myeloproliferative neoplasms

Duncombe, A. S., Anderson, L., James, G., De Vocht, F., Fritschi, L., Mesa, R., Clarke, M. & McMullin, M., 01 Feb 2020, In : HemaSphere. 4, 1, 6 p., 0327.

Research output: Contribution to journalArticle

Open Access
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26 Downloads (Pure)

Safety and efficacy of the maximum tolerated dose of givinostat in polycythemia vera: a two-part Phase Ib/II study

Rambaldi, A., Iurlo, A., Vannucchi, A. M., Noble, R., von Bubnoff, N., Guarini, A., Martino, B., Pezzutto, A., Carli, G., De Muro, M., Luciani, S., McMullin, M. F., Cambier, N., Marolleau, J-P., Mesa, R. A., Tibes, R., Pancrazzi, A., Gesullo, F., Bettica, P., Manzoni, S. & 1 others, Di Tollo, S., 11 Feb 2020, In : Leukemia.

Research output: Contribution to journalArticle

Open Access
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19 Downloads (Pure)
2019

A Comparison of Inpatient and Outpatient-Based Chemotherapy Regimens for the Treatment of Acute Myeloid Leukaemia In The Elderly

Daly, A. B., Cuthbert, R., Finnegan, D., Arnold, C., Craddock, C. & McMullin, M. F., Jan 2019, In : The Ulster Medical Journal. 88, 1, p. 25-29 5 p.

Research output: Contribution to journalArticle

Open Access
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26 Downloads (Pure)

A guideline for the management of specific situations in polycythaemia vera and secondary erythrocytosis: A British Society for Haematology Guideline

British Society for Haematology Guideline, 09 Jan 2019, In : British Journal of Haematology. 184, 2, p. 161-175 15 p.

Research output: Contribution to journalArticle

Open Access
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13 Citations (Scopus)
27 Downloads (Pure)

A molecular diagnostic algorithm for JAK2 V617F investigations in suspected myeloproliferative neoplasms

Catherwood, M. A., McAllister, R., McCallion, P., McGimpsey, J. E., Hindley, A., Feerick, J., Greenfield, G., Kennedy, P., Benson, G., Arnold, C., Merron, B. & McMullin, M. F., 25 Oct 2019, In : Irish journal of medical science.

Research output: Contribution to journalArticle

Arterial thrombosis in Philadelphia-negative myeloproliferative neoplasms predicts second cancer. A case-control study

De Stefano, V., Ghirardi, A., Masciulli, A., Carobbio, A., Palandri, F., Vianelli, N., Rossi, E., Betti, S., Di Veroli, A., Iurlo, A., Cattaneo, D., Finazzi, G., Bonifacio, M., Scaffidi, L., Patriarca, A., Rumi, E., Casetti, I. C., Stephenson, C. I. M., Guglielmelli, P., Elli, E. M. & 23 others, Palova, M., Rapezzi, D., Erez, D., Gomez, M., Wille, K., Perez-Encinas, M., Lunghi, F., Angona, A., Fox, M-L., Beggiato, E., Benevolo, G., Carli, G., Cacciola, R., McMullin, M. F., Tieghi, A., Recasens, V., Isfort, S., Marchetti, M., Griesshammer, M., Alvarez-Larran, A., Vannucchi, A. M., Rambaldi, A. & Barbui, T., 23 Dec 2019, In : Blood.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Diagnostic workflow for hereditary erythrocytosis and thrombocytosis

McMullin, M. F., 06 Dec 2019, In : Hematology (United States). 2019, 1, p. 391-396 6 p.

Research output: Contribution to journalArticle

Open Access
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40 Downloads (Pure)

Facing erythrocytosis results of an international physician survey

Rumi, E., McMullin, M. F., Harrison, C., Ellis, M. H., Barzilai, M., Sarid, N., Mesa, R., Paoli, C., Angona, A., Sant'Antonio, E., Ferretti, V. V., Cavalloni, C., Casetti, I. C., Trotti, C. & Barbui, T., 31 May 2019, In : American Journal of Hematology.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Methylation age as a correlate for allele burden, disease status and clinical response in myeloproliferative neoplasm patients treated with Vorinostat

McPherson, S., Greenfield, G., Andersen, C., Grinfeld, J., Hasselbalch, H., Nangalia, J., Mills, K. I. & McMullin, M. F., 26 Sep 2019, In : Experimental Hematology.

Research output: Contribution to journalArticle

Open Access

Reducing the burden of MPN

McMullin, M. F., 31 Oct 2019, In : Blood. 134, 18, p. 1483-1484 2 p.

Research output: Contribution to journalArticle

Response to Imatinib therapy is inferior for e13a2 BCR-ABL1 transcript type in comparison to e14a2 transcript type in chronic myeloid leukaemia

Greenfield, G., McMullan, R., Robson, N., McGimpsey, J., Catherwood, M. & McMullin, M. F., 02 May 2019, In : EMJ Hematology. 19, p. 7

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)
80 Downloads (Pure)
Open Access
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1 Citation (Scopus)
21 Downloads (Pure)

Second cancer in Philadelphia negative myeloproliferative neoplasms (MPN-K). A nested case-control study

Barbui, T., Ghirardi, A., Masciulli, A., Carobbio, A., Palandri, F., Vianelli, N., De Stefano, V., Betti, S., Di Veroli, A., Iurlo, A., Cattaneo, D., Delaini, F., Bonifacio, M., Scaffidi, L., Patriarca, A., Rumi, E., Casetti, I. C., Stephenson, C., Guglielmelli, P., Elli, E. M. & 21 others, Palova, M., Bertolotti, L., Erez, D., Gomez, M., Wille, K., Perez-Encinas, M., Lunghi, F., Angona, A., Fox, M. L., Beggiato, E., Benevolo, G., Carli, G., Cacciola, R., McMullin, M. F., Tieghi, A., Recasens, V., Marchetti, M., Griesshammer, M., Alvarez-Larran, A., Vannucchi, A. M. & Finazzi, G., 29 May 2019, In : Leukemia. 10 p.

Research output: Contribution to journalArticle

Open Access
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15 Citations (Scopus)
79 Downloads (Pure)

Second cancers in MPN: Survival analysis from an international study

Marchetti, M., Ghirardi, A., Masciulli, A., Carobbio, A., Palandri, F., Vianelli, N., Rossi, E., Betti, S., Di Veroli, A., Iurlo, A., Cattaneo, D., Finazzi, G., Bonifacio, M., Scaffidi, L., Patriarca, A., Rumi, E., Casetti, I. C., Stephenson, C., Guglielmelli, P., Elli, E. M. & 24 others, Palova, M., Rapezzi, D., Erez, D., Gomez, M., Wille, K., Perez-Encinas, M., Lunghi, F., Angona, A., Fox, M. L., Beggiato, E., Benevolo, G., Carli, G., Cacciola, R., McMullin, M. F., Tieghi, A., Recasens, V., Isfort, S., Pane, F., De Stefano, V., Griesshammer, M., Alvarez-Larran, A., Vannucchi, A. M., Rambaldi, A. & Barbui, T., 22 Dec 2019, In : American Journal of Hematology.

Research output: Contribution to journalArticle

2 Citations (Scopus)

The histone deacetylase inhibitor Romidepsin induces as a cascade of differential gene expression and altered Histone H3K9 marks in myeloid leukaemia cells

Clarke, K., Young, C., Liberante, F., McMullin, M., Thompson, A. & Mills, K., 29 May 2019, In : Oncotarget. 10, 37, p. 3462-3471 9 p.

Research output: Contribution to journalArticle

Open Access
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110 Downloads (Pure)

The poor outcome in high molecular risk, hydroxycarbamide resistant/intolerant ET is not ameliorated by ruxolitinib

O'Sullivan, J. M., Hamblin, A., Yap, C., Fox, S., Boucher, R., Panchal, A., Alimam, S., Dreau, H. M., Howard, K., Ware, P., Cross, N. C., McMullin, M. F., Harrison, C. N. & Mead, A. J., 02 Oct 2019, In : Blood.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2018

Absence of CALR Mutations in Idiopathic Erythrocytosis Patients with Low Serum Erythropoietin Levels

Catherwood, M. A., Graham, A., Cuthbert, R. J. G., Garrec, C., Gardie, B., Girodon, F., Laird, S., Cross, N. C. P. & McMullin, M. F., 30 May 2018, In : Acta haematologica. 139, 4, p. 217-219 3 p.

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)
210 Downloads (Pure)
Open Access
File
37 Downloads (Pure)
Open Access
File
12 Citations (Scopus)
54 Downloads (Pure)

Classification and Personalized Prognosis in Myeloproliferative Neoplasms

Grinfeld, J., Nangalia, J., Baxter, E. J., Wedge, D. C., Angelopoulos, N., Cantrill, R., Godfrey, A. L., Papaemmanuil, E., Gundem, G., MacLean, C., Cook, J., O'Neil, L., O'Meara, S., Teague, J. W., Butler, A. P., Massie, C. E., Williams, N., Nice, F. L., Andersen, C. L., Hasselbalch, H. C. & 7 others, Guglielmelli, P., McMullin, M. F., Vannucchi, A. M., Harrison, C. N., Gerstung, M., Green, A. R. & Campbell, P. J., 11 Oct 2018, In : New England Journal of Medicine. 379, 15, p. 1416-1430 15 p.

Research output: Contribution to journalArticle

Open Access
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68 Citations (Scopus)
411 Downloads (Pure)

Hydroxycarbamide plus Aspirin vs Aspirin Alone in Patients with Essential Thrombocythaemia Aged 40-59 Years Without High-Risk Features

Godfrey, A. L., Campbell, P. J., MacLean, C., Buck, G., Cook, J., Temple, J., Wheatley, K., Wilkins, B. S., Nangalia, J., Grinfield, J., McMullin, M., Forsyth, C., Kiladjian, J. J., Green, AR. & Harrison, C., 28 Aug 2018, In : Journal of Clinical Oncology. 11 p.

Research output: Contribution to journalArticle

Open Access
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6 Citations (Scopus)
331 Downloads (Pure)
Open Access
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2 Citations (Scopus)
182 Downloads (Pure)
1 Citation (Scopus)
2017
Open Access
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210 Downloads (Pure)

HFE mutations in idiopathic erythrocytosis

Biagetti, G., Catherwood, M., Robson, N., Bertozzi, I., Cosi, E., McMullin, M. F. & Randi, M. L., 07 Feb 2017, In : British Journal of Haematology.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
188 Downloads (Pure)

Outcome of azacitidine therapy in acute myeloid leukaemia is not improved by concurrent vorinostat therapy but is predicted by a diagnostic molecular signature

Craddock, C., Houlton, A. E., Quek, L. S., Ferguson, P., Gbandi, E., Roberts, C., Metzner, M., Garcia-Martin, N., Kennedy, A., Hamblin, A., Raghavan, M., Nagra, S., Dudley, L., Wheatley, K., McMullin, M., Pillai, S. P., kelly, R. J., Siddique, S., Dennis, M., Cavenagh, J. D. & 1 others, Vyas, P., 01 Aug 2017, In : Clinical Cancer Research.

Research output: Contribution to journalArticle

Open Access
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27 Citations (Scopus)
74 Downloads (Pure)

Ruxolitinib versus best available therapy for ET intolerant or resistant to hydroxycarbamide in a randomised trial

Harrison, C. N., Mead, A. J., Panchal, A., McMullin, M., Fox, S., Yap, C., Gbandi, E., Houlton, A., Alimam, S., Ewing, J., Wood, M., Chen, F., Coppell, J., Panoskaltsis, N., knapper, S., Ali, S., Hmblin, A., Scherber, R., Dueck, A. C., Cross, N. & 1 others, Rubin, M., 09 Aug 2017, In : Blood.

Research output: Contribution to journalArticle

Open Access
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46 Citations (Scopus)
119 Downloads (Pure)
2016

(32)P in the treatment of myeloproliferative disorders

Lawless, S., McMullin, M. F., Cuthbert, R. & Houston, R., May 2016, In : The Ulster Medical Journal. 85, 2, p. 83-5 3 p.

Research output: Contribution to journalArticle

Open Access
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2 Citations (Scopus)
96 Downloads (Pure)

Antiplatelet therapy versus observation in low-risk essential thrombocythemia with CALR mutation

Alvarez-Larrán, A., Pereira, A., Guglielmelli, P., Hernández-Boluda, J. C., Arellano-Rodrigo, E., Ferrer-Marín, F., Samah, A., Griesshammer, M., Kerguelen, A., Andreasson, B., Burgaleta, C., Schwarz, J., García-Gutiérrez, V., Ayala, R., Barba, P., Gómez-Casares, M. T., Paoli, C., Drexler, B., Zweegman, S., McMullin, M. F. & 5 others, Samuelsson, J., Harrison, C., Cervantes, F., Vannucchi, A. M. & Besses, C., 12 May 2016, In : HAEMATOLOGICA.

Research output: Contribution to journalArticle

Open Access
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47 Citations (Scopus)
142 Downloads (Pure)

A randomized study of pomalidomide vs placebo in persons with myeloproliferative neoplasm-associated myelofibrosis and RBC-transfusion dependence

Tefferi, A., Al-Ali, H. K., Barosi, G., Devos, T., Gisslinger, H., Jiang, Q., Kiladjian, J-J., Mesa, R., Passamonti, F., McMullin, M. F., Ribrag, V., Schiller, G., Vannucchi, A. M., Zhou, D., Reiser, D., Zhong, J. & Gale, R. P., 18 Nov 2016, In : Leukemia. 31, 5, p. 1252

Research output: Contribution to journalArticle

Open Access
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2 Citations (Scopus)
146 Downloads (Pure)

Coexistence of inversion 16 in chronic myeloid leukaemia in blast crisis

Catherwood, M. A., McGrattan, P., Lawless, S., McConville, C., Robson, N., Lundy, B., Humphreys, M., Soverini, S., Mills, K. I. & McMullin, M. F., 01 Dec 2016, In : Journal of Hematopathology. 9, 4, p. 155-160 6 p.

Research output: Contribution to journalArticle

Congenital erythrocytosis

McMullin, M. F., May 2016, In : International Journal of Laboratory Hematology. 38, s1

Research output: Contribution to journalArticle

Open Access
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5 Citations (Scopus)
177 Downloads (Pure)
Open Access
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211 Downloads (Pure)

Gene Panel Sequencing Improves The Diagnostic Work-Up Of Patients With Idiopathic Erythrocytosis And Identifies New Mutations

Camps, C., Petousi, N., Bento, C., Cario, H., Copley, R. R., McMullin, M. F., van Wijk, R., Ratcliffe, P. J., Robbins, P. A., Taylor, J. C. & WGS500 Consortium, 01 Nov 2016, In : HAEMATOLOGICA. 101, 11, p. 1306-1318 13 p.

Research output: Contribution to journalArticle

Open Access
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23 Citations (Scopus)
157 Downloads (Pure)

Investigation and Management of Erythrocytosis

McMullin, M. F., 16 Jul 2016, In : Current hematologic malignancy reports.

Research output: Contribution to journalArticle

Open Access
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10 Citations (Scopus)
248 Downloads (Pure)

LNK mutations and myeloproliferative disorders

McMullin, M. F. & Cario, H., Feb 2016, In : American Journal of Hematology. 91, 2

Research output: Contribution to journalArticle

15 Citations (Scopus)

Management of polycythaemia vera: a critical review of current data

McMullin, M. F., Wilkins, B. S. & Harrison, C. N., Feb 2016, In : British Journal of Haematology. 172, 3, p. 337–349 13 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Minor allele frequency of myeloproliferative neoplasm mutations in the Irish blood donor population

Titmarsh, G. J., McKay, G. J., Lawler, M., Anderson, L. A. & McMullin, M. F., Sep 2016, In : Hematological Oncology. 31, 3, p. 161-164 4 p.

Research output: Contribution to journalArticle

Patient perspectives of a diagnosis of myeloproliferative neoplasm in a case control study

McMullin, M., James, G., Duncombe, A. S., De Vocht, F., Fritschi, L., Clarke, M. & Anderson, L., 26 May 2016, In : Experimental hematology & oncology. 5, 14, 5 p.

Research output: Contribution to journalArticle

Open Access
File
247 Downloads (Pure)

The Calreticulin gene and myeloproliferative neoplasms

Clinton, A. & McMullin, M. F., 28 Jun 2016, In : Journal of Clinical Pathology.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
554 Downloads (Pure)

The prevalence of CALR mutations in a cohort of patients with myeloproliferative neoplasms

Grinsztejn, E., Percy, M. J., McClenaghan, D., Quintana, M., Cuthbert, R. J. G. & McMullin, M. F., Feb 2016, In : International Journal of Laboratory Hematology. 38, 1, p. 102-106 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Variabilidad de la respuesta plaquetaria a la aspirina

Translated title of the contribution: Assessing platelet response to aspirinFairley, S. L., McKeown, P. P., Kee, F., McMullin, M. F., Stevenson, M. & Muir, A. R., 01 Oct 2016, In : Salud(i)Ciencia. 22, 3, p. 229-234 6 p.

Research output: Contribution to journalArticle

Which patients with myelofibrosis should receive ruxolitinib therapy? ELN-SIE evidence-based recommendations

Marchetti, M., Barosi, G., Cervantes, F., Birgegård, G., Griesshammer, M., Harrison, C., Hehlmann, R., Kiladjian, J-J., Kröger, N., McMullin, M. F., Passamonti, F., Vannucchi, A. & Barbui, T., 14 Oct 2016, In : Leukemia. 7 p.

Research output: Contribution to journalArticle

Open Access
File
25 Citations (Scopus)
1214 Downloads (Pure)
2015

A Japanese Family with Congenital Erythrocytosis Caused by Haemoglobin Bethesda

Tamura, S., Tamura, T., Gima, H., Nishikawa, A., Okamoto, Y., Kanazawa, N., Relvas, L., Cunha, E., Frances McMullin, M. & Bento, C., 2015, In : Archives of Internal Medicine. 54, 18, p. 2389-93 5 p.

Research output: Contribution to journalArticle

A randomised comparison of daunorubicin 90mg/m2 vs 60mg/m2 in AML induction: results from the UK NCRI AML17 trial in 1206 patients

Burnett, A. K., Russell, N. H., Hills, R. K., Kell, J., Cavenagh, J., Kjeldsen, L., McMullin, M-F., Cahalin, P., Dennis, M., Friis, L., Thomas, I. F., Milligan, D. & Clark, R. E., 2015, In : Blood. p. 3878-3885 8 p.

Research output: Contribution to journalArticle

112 Citations (Scopus)

Arsenic trioxide and all-trans retinoic acid treatment for acute promyelocytic leukaemia in all risk groups (AML17): results of a randomised, controlled, phase 3 trial

Burnett, A. K., Russell, N. H., Hills, R. K., Bowen, D., Kell, J., Knapper, S., Morgan, Y. G., Lok, J., Grech, A., Jones, G., Khwaja, A., Friis, L., McMullin, M. F., Hunter, A., Clark, R. E., Grimwade, D. & UK National Cancer Research Institute Acute Myeloid Leukaemia Working Group, Oct 2015, In : Lancet Oncology. 16, 13, p. 1295-305 11 p.

Research output: Contribution to journalArticle

194 Citations (Scopus)

Clinical end points for drug treatment trials in BCR-ABL1-negative classic myeloproliferative neoplasms: consensus statements from European LeukemiaNET (ELN) and Internation Working Group-Myeloproliferative Neoplasms Research and Treatment (IWG-MRT)

Barosi, G., Tefferi, A., Besses, C., Birgegard, G., Cervantes, F., Finazzi, G., Gisslinger, H., Griesshammer, M., Harrison, C., Hehlmann, R., Hermouet, S., Kiladjian, J-J., Kröger, N., Mesa, R., McMullin, M. F., Pardanani, A., Passamonti, F., Samuelsson, J., Vannucchi, A. M., Reiter, A. & 4 others, Silver, R. T., Verstovsek, S., Tognoni, G. & Barbui, T., 2015, In : Leukemia. 29, p. 20-26 7 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Factors influencing success of clinical genome sequencing across a broad spectrum of disorders

Taylor, J. C., Martin, H. C., Lise, S., Broxholme, J., Cazier, J-B., Rimmer, A., Kanapin, A., Lunter, G., Fiddy, S., Allan, C., Aricescu, A. R., Attar, M., Babbs, C., Becq, J., Beeson, D., Bento, C., Bignell, P., Blair, E., Buckle, V. J., Bull, K. & 90 others, Cais, O., Cario, H., Chapel, H., Copley, R. R., Cornall, R., Craft, J., Dahan, K., Davenport, E. E., Dendrou, C., Devuyst, O., Fenwick, A. L., Flint, J., Fugger, L., Gilbert, R. D., Goriely, A., Green, A., Greger, I. H., Grocock, R., Gruszczyk, A. V., Hastings, R., Hatton, E., Higgs, D., Hill, A., Holmes, C., Howard, M., Hughes, L., Humburg, P., Johnson, D., Karpe, F., Kingsbury, Z., Kini, U., Knight, J. C., Krohn, J., Lamble, S., Langman, C., Lonie, L., Luck, J., McCarthy, D., McGowan, S. J., McMullin, M. F., Miller, K. A., Murray, L., Németh, A. H., Nesbit, M. A., Nutt, D., Ormondroyd, E., Oturai, A. B., Pagnamenta, A., Patel, S. Y., Percy, M., Petousi, N., Piazza, P., Piret, S. E., Polanco-Echeverry, G., Popitsch, N., Powrie, F., Pugh, C., Quek, L., Robbins, P. A., Robson, K., Russo, A., Sahgal, N., van Schouwenburg, P. A., Schuh, A., Silverman, E., Simmons, A., Sørensen, P. S., Sweeney, E., Taylor, J., Thakker, R. V., Tomlinson, I., Trebes, A., Twigg, S. R. F., Uhlig, H. H., Vyas, P., Vyse, T., Wall, S. A., Watkins, H., Whyte, M. P., Witty, L., Wright, B., Yau, C., Buck, D., Humphray, S., Ratcliffe, P. J., Bell, J. I., Wilkie, A. O. M., Bentley, D., Donnelly, P. & McVean, G., Jul 2015, In : Nature Genetics. 47, 7, p. 717-26 10 p.

Research output: Contribution to journalArticle

163 Citations (Scopus)

Identification and validation of the dopamine agonist bromocriptine as a novel therapy for high-risk myelodysplastic syndromes and secondary acute myeloid leukemia

Liberante, F. G., Pouryahya, T., McMullin, M-F., Zhang, S-D. & Mills, K. I., 28 Dec 2015, In : Oncotarget. 7, 6, p. 6609-6619

Research output: Contribution to journalArticle

Open Access
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7 Citations (Scopus)
264 Downloads (Pure)
3 Citations (Scopus)